BR112015012491A2 - composição de melatonina ou seus derivados com coenzima q10 e seu uso contra o envelhecimento da pele - Google Patents

composição de melatonina ou seus derivados com coenzima q10 e seu uso contra o envelhecimento da pele

Info

Publication number
BR112015012491A2
BR112015012491A2 BR112015012491A BR112015012491A BR112015012491A2 BR 112015012491 A2 BR112015012491 A2 BR 112015012491A2 BR 112015012491 A BR112015012491 A BR 112015012491A BR 112015012491 A BR112015012491 A BR 112015012491A BR 112015012491 A2 BR112015012491 A2 BR 112015012491A2
Authority
BR
Brazil
Prior art keywords
composition
melatonin
coenzyme
derivatives
skin aging
Prior art date
Application number
BR112015012491A
Other languages
English (en)
Other versions
BR112015012491B1 (pt
Inventor
Acuña Castroviejo Darío
Escames Rosa Germaine
Carlos López García Luis
Original Assignee
Univ Granada
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Granada filed Critical Univ Granada
Publication of BR112015012491A2 publication Critical patent/BR112015012491A2/pt
Publication of BR112015012491B1 publication Critical patent/BR112015012491B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • A61K8/492Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • A61K8/355Quinones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/78Enzyme modulators, e.g. Enzyme agonists

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1/1 resumo composição de melatonina ou seus derivados com coenzima q10 e seu uso contra o envelhecimento da pele a presente invenção se refere a uma composição que compreende melatonina, metabólito ou derivado da mesma e coenzima q10 e seu uso para a elaboração de uma composição cosmética ou farmacêutica para o tratamento da pele, já que esta composição potencializa a entrada de ambas as moléculas na mitocôndria e facilita uma absorção transdérmica, podendo alcançar tanto a melatonina quanto a coq10 todos os estratos da pele.
BR112015012491-7A 2012-11-28 2013-11-26 Composição de melatonina ou seus derivados com coenzima q10 e seu uso contra o envelhecimento da pele BR112015012491B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES201231849A ES2394245B2 (es) 2012-11-28 2012-11-28 Composición de melatonina o sus derivados con coenzima q10 y su uso contra el envejecimiento de la piel
ESP201231849 2012-11-28
PCT/ES2013/070817 WO2014083227A1 (es) 2012-11-28 2013-11-26 Composición de melatonina o sus derivados con coenzima q10 y su uso contra el envejecimiento de la piel

Publications (2)

Publication Number Publication Date
BR112015012491A2 true BR112015012491A2 (pt) 2017-07-11
BR112015012491B1 BR112015012491B1 (pt) 2020-03-17

Family

ID=47520437

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015012491-7A BR112015012491B1 (pt) 2012-11-28 2013-11-26 Composição de melatonina ou seus derivados com coenzima q10 e seu uso contra o envelhecimento da pele

Country Status (10)

Country Link
US (4) US10092544B2 (pt)
EP (1) EP2926800B1 (pt)
BR (1) BR112015012491B1 (pt)
ES (2) ES2394245B2 (pt)
HR (1) HRP20191256T1 (pt)
PL (1) PL2926800T3 (pt)
PT (1) PT2926800T (pt)
SI (1) SI2926800T1 (pt)
TR (1) TR201911262T4 (pt)
WO (1) WO2014083227A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2684408B1 (es) * 2017-03-31 2019-07-09 Univ Granada Uso de melatonina para el tratamiento de tumores
WO2018211297A1 (en) * 2017-05-18 2018-11-22 Pacini Nicola Improved dermatological formulations for cosmetic and pharmacological use, and cosmetic and pharmacological product prepared by means of said formulations
US11419849B1 (en) 2019-02-06 2022-08-23 Kitt Bio, Inc. Methods and products for adverse effects of air travel, jet lag, or a change to a sleep wake timing cycle

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048886A (en) * 1998-10-05 2000-04-11 Neigut; Stanley Compositions and delivery systems for the topical treatment of psoriasis and other conditions of the skin
US6689385B2 (en) * 2000-11-03 2004-02-10 Chronorx Llc Formulations for the treatment of insulin resistance and type 2 diabetes mellitus
US20030167556A1 (en) * 2002-03-05 2003-09-11 Consumers Choice Systems, Inc. Methods and devices for transdermal delivery of anti-aging compounds for treatment and prevention of facial or neck skin aging
US6815122B2 (en) 2002-03-06 2004-11-09 Valence Technology, Inc. Alkali transition metal phosphates and related electrode active materials
NZ537359A (en) * 2002-06-25 2006-10-27 Cosmeceutic Solutions Pty Ltd Topical cosmetic compositions for transdermal delivery
RU2006101991A (ru) 2003-06-25 2006-06-27 Чарлз ЭРВИН (US) Химическая композиция и способ увеличения подачи кофермента q10
US20060286046A1 (en) * 2005-01-05 2006-12-21 Haber C Andrew Skin care compositions
ITRM20060108A1 (it) * 2006-03-03 2007-09-04 Colella Gino Composizioni a base di melatonina e sostanze immunostimolanti
DE102007039741A1 (de) * 2007-08-22 2009-02-26 Henkel Ag & Co. Kgaa Haarbehandlungsmittel mit Tensid(en) und Melatonin/Agomelatin

Also Published As

Publication number Publication date
EP2926800A4 (en) 2016-05-18
ES2394245A1 (es) 2013-01-30
PL2926800T3 (pl) 2019-10-31
EP2926800B1 (en) 2019-05-29
HRP20191256T1 (hr) 2019-10-18
PT2926800T (pt) 2019-08-05
BR112015012491B1 (pt) 2020-03-17
US20180311133A1 (en) 2018-11-01
ES2394245B2 (es) 2013-12-16
SI2926800T1 (sl) 2019-09-30
US20230414470A1 (en) 2023-12-28
WO2014083227A1 (es) 2014-06-05
ES2734480T3 (es) 2019-12-10
EP2926800A1 (en) 2015-10-07
US20230031519A1 (en) 2023-02-02
TR201911262T4 (tr) 2019-08-21
US20150306072A1 (en) 2015-10-29
US10092544B2 (en) 2018-10-09

Similar Documents

Publication Publication Date Title
CO2019005287A2 (es) Compuestos de 7-feniletilamino-4h-pirimido[4,5-d][1,3]-oxazin-2-ona como inhibidores de idh1 e idh2 mutantes
BR112014018429A8 (pt) Método para tratar um paciente que sofre de não-24, e, método para o tratamento crônico de não-24 em uma pessoa que está totalmente cega
CL2015002567A1 (es) Compuestos y sus usos para modular la hemoglobina
BR112014006455A2 (pt) alquilamidotiazóis, preparações cosméticas ou dermatológicas com um teor de um ou vários alquilamidotiazóis e uso de um ou vários alquilamidotiazóis
BR112015026023A2 (pt) derivados de 2- aminopirido[4,3-d]pirimidin-5-ona e seu uso como inibidores de wee-1
BR112013000537A2 (pt) composição aquosa contendo bromexina
CL2016000950A1 (es) Composición farmacéutica acuosa que comprende insulina glulisina y metionina; kit farmacéutico; uso en el tratamiento de la diabetes tipo 1 ó 2.
CL2012000026A1 (es) Formulación farmacéutica acuosa que contiene una insulina, un análogo de insulina o un derivado insulínico, o una de sus sales farmacológicamente tolerables, y metionina; proceso para preparar dicha formulación; medicamento que la contiene; y su uso para tratar la diabetes mellitus.
BR112013024025A8 (pt) Composição fluida destinada a ser aplicada na pele
BR112017016759A2 (pt) recipiente de plástico pré-carregado, kit, uso do recipiente de plástico pré-carregado, método para o tratamento de uma doença ou condição, método para o tratamento cosmético da pele
BR112015014619A2 (pt) tratamento de transtornos do ritmo circadiano
BR112016000350A8 (pt) métodos de tratamento de lesões inflamatórias da rosácea e usos de uma composição farmacêutica
BR112015024926A2 (pt) composições, artigo de fabricação, métodos para tratar um paciente com câncer, para avaliar uma composição, para avaliar a atividade biológica, para produzir uma composição e para avaliar a fragmentação de uma composição e variante de pertuzumabe
CL2014001704A1 (es) Derivados de amida ciclica como inhibidores de 11-beta-hidroxiesteroide deshidrogenasa; composicion farmaceutica que los comprende y el uso de los mismos en la prevencion o tratamiento de enfermedades tales como la diabetes.
BR112013022961B8 (pt) Artigo absorvente
BR112015017251A8 (pt) composições farmacêuticas compreendendo doadores de nitroxil, misturas e usos das referidas composições farmacêuticas
BR112015027440A2 (pt) DERIVADO DE [1,2,4]TRIAZOL[4,3-a]PIRIDINA, MÉTODO DE PREPA-RAÇÃO OU APLICAÇÃO MÉDICA DO DERIVADO
BR112015019873A2 (pt) inibidores macrocíclicos da lrrk2 cinase
BR112014017481A8 (pt) formulação em pó seco para uso em um inalador de pó seco, inalador de pó seco e uso de uma formulação
BR112013017953A2 (pt) Composição farmacêutica, formulação tópica, método, e, composição fotossensibilizadora
CO7101244A2 (es) Fenilimidazopirazoles sustituidos y su uso
AR106364A1 (es) Derivados de insulina y sus usos médicos
BR112014027047A2 (pt) nova formulação
BR112015013783A2 (pt) quitina ou seus derivados para a prevenção e / ou tratamento de parasitoses
BR112016007487A2 (pt) composições compreendendo citrulina e leucina e seu uso no tratamento de diabetes e de síndrome meta-bólica

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA.

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 26/11/2013, OBSERVADAS AS CONDICOES LEGAIS.