BR112015004791A8 - processo para preparar seletivamente diidroxietil piperazina, método para a síntese de diidroxietil piperazina, produto e diidroxietil piperazina sintética - Google Patents

processo para preparar seletivamente diidroxietil piperazina, método para a síntese de diidroxietil piperazina, produto e diidroxietil piperazina sintética

Info

Publication number
BR112015004791A8
BR112015004791A8 BR112015004791A BR112015004791A BR112015004791A8 BR 112015004791 A8 BR112015004791 A8 BR 112015004791A8 BR 112015004791 A BR112015004791 A BR 112015004791A BR 112015004791 A BR112015004791 A BR 112015004791A BR 112015004791 A8 BR112015004791 A8 BR 112015004791A8
Authority
BR
Brazil
Prior art keywords
dihydroxyethyl piperazine
piperazine
dihydroxyethyl
synthesis
synthetic
Prior art date
Application number
BR112015004791A
Other languages
English (en)
Other versions
BR112015004791A2 (pt
Inventor
Macdonald Jason
Arrowood Tina
Original Assignee
Dow Global Technologies Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Global Technologies Llc filed Critical Dow Global Technologies Llc
Publication of BR112015004791A2 publication Critical patent/BR112015004791A2/pt
Publication of BR112015004791A8 publication Critical patent/BR112015004791A8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J27/00—Catalysts comprising the elements or compounds of halogens, sulfur, selenium, tellurium, phosphorus or nitrogen; Catalysts comprising carbon compounds
    • B01J27/20—Carbon compounds
    • B01J27/232—Carbonates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/0215—Sulfur-containing compounds
    • B01J31/0225—Sulfur-containing compounds comprising sulfonic acid groups or the corresponding salts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/0234—Nitrogen-, phosphorus-, arsenic- or antimony-containing compounds
    • B01J31/0235—Nitrogen containing compounds
    • B01J31/0244—Nitrogen containing compounds with nitrogen contained as ring member in aromatic compounds or moieties, e.g. pyridine
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)

Abstract

resumo “processo para preparar seletivamente diidroxietil piperazina, método para a síntese de diidroxietil piperazina, produto e diidroxietil piperazina sintética” processo para seletivamente preparar diidroxietil piperazina, reagindo hidroxietiloxazolidinona com um catalisador ácido, sendo que a seletividade de hidroxietiloxazolidinona a diidroxietil piperazina é de pelo menos 55%. 1/1
BR112015004791A 2012-09-05 2013-09-04 processo para preparar seletivamente diidroxietil piperazina, método para a síntese de diidroxietil piperazina, produto e diidroxietil piperazina sintética BR112015004791A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261697094P 2012-09-05 2012-09-05
PCT/US2013/058054 WO2014039551A1 (en) 2012-09-05 2013-09-04 Preparation of dihydroxyethyl piperazine

Publications (2)

Publication Number Publication Date
BR112015004791A2 BR112015004791A2 (pt) 2017-07-04
BR112015004791A8 true BR112015004791A8 (pt) 2017-12-12

Family

ID=49474680

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015004791A BR112015004791A8 (pt) 2012-09-05 2013-09-04 processo para preparar seletivamente diidroxietil piperazina, método para a síntese de diidroxietil piperazina, produto e diidroxietil piperazina sintética

Country Status (11)

Country Link
US (1) US9328080B2 (pt)
EP (1) EP2892883B1 (pt)
CN (1) CN104755466B (pt)
AU (1) AU2013312767B2 (pt)
BR (1) BR112015004791A8 (pt)
CA (1) CA2881689A1 (pt)
MX (1) MX2015002903A (pt)
RU (1) RU2015112310A (pt)
SA (1) SA515360071B1 (pt)
WO (1) WO2014039551A1 (pt)
ZA (1) ZA201501113B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106543104B (zh) * 2016-11-04 2019-02-01 山东铂源药业有限公司 一种1-(2-羟基乙基)哌嗪的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4338443A (en) 1980-08-15 1982-07-06 Texaco Inc. Synthesis of N-(2-hydroxyethyl)piperazine
US5098681A (en) 1990-08-16 1992-03-24 The Dow Chemical Company Process for absorption of sulfur compounds from fluids
US5491263A (en) 1993-12-21 1996-02-13 The Dow Chemical Company Aminoethylation process for production of substituted ethylene diamines
US8436169B2 (en) * 2010-10-29 2013-05-07 Basf Se Process for preparing 1,4-bishydroxyethylpiperazine

Also Published As

Publication number Publication date
MX2015002903A (es) 2015-06-03
US9328080B2 (en) 2016-05-03
RU2015112310A (ru) 2016-10-27
ZA201501113B (en) 2016-04-28
CN104755466B (zh) 2016-08-17
SA515360071B1 (ar) 2015-11-03
BR112015004791A2 (pt) 2017-07-04
AU2013312767A1 (en) 2015-03-19
EP2892883A1 (en) 2015-07-15
AU2013312767B2 (en) 2017-06-15
WO2014039551A1 (en) 2014-03-13
CN104755466A (zh) 2015-07-01
US20150274682A1 (en) 2015-10-01
CA2881689A1 (en) 2014-03-13
EP2892883B1 (en) 2016-10-26

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA.

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2530 DE 02-07-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.