BR112015004695A2 - isoxazolinas espirocíclicas como agentes antiparasitários - Google Patents

isoxazolinas espirocíclicas como agentes antiparasitários

Info

Publication number
BR112015004695A2
BR112015004695A2 BR112015004695A BR112015004695A BR112015004695A2 BR 112015004695 A2 BR112015004695 A2 BR 112015004695A2 BR 112015004695 A BR112015004695 A BR 112015004695A BR 112015004695 A BR112015004695 A BR 112015004695A BR 112015004695 A2 BR112015004695 A2 BR 112015004695A2
Authority
BR
Brazil
Prior art keywords
antiparasitic agents
spirocyclic
isoxazolines
spirocyclic isoxazolines
parasiticide
Prior art date
Application number
BR112015004695A
Other languages
English (en)
Inventor
Menon Sanjay
M K Sheehan Susan
A Vailliancourt Valerie
Original Assignee
Zoetis Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zoetis Llc filed Critical Zoetis Llc
Publication of BR112015004695A2 publication Critical patent/BR112015004695A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/20—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10—Spiro-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

resumo patente de invenção: "isoxazolinas espirocíclicas como agentes antiparasitários". a invenção refere-se a derivados de isoxazolina espirocíclica de fórmula (1) estereoisômeros dos mesmos, sais veterinários ou farmacêuticos aceitáveis dos mesmos, composições dos mesmos, processos para preparar, e seu uso como um parasiticida em um animal. as variáveis w1, w2, w3, w, x, r1a, r1b, r1c, r2, r3, r4, e n são como descritas aqui.
BR112015004695A 2012-09-07 2013-09-04 isoxazolinas espirocíclicas como agentes antiparasitários BR112015004695A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261698004P 2012-09-07 2012-09-07
PCT/US2013/057935 WO2014039484A1 (en) 2012-09-07 2013-09-04 Spirocyclic isoxazolines as antiparasitic agents

Publications (1)

Publication Number Publication Date
BR112015004695A2 true BR112015004695A2 (pt) 2017-07-04

Family

ID=49170907

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015004695A BR112015004695A2 (pt) 2012-09-07 2013-09-04 isoxazolinas espirocíclicas como agentes antiparasitários

Country Status (8)

Country Link
US (1) US9131697B2 (pt)
EP (1) EP2892901A1 (pt)
CN (1) CN104603140A (pt)
AU (1) AU2013312891A1 (pt)
BR (1) BR112015004695A2 (pt)
CA (1) CA2882546A1 (pt)
HK (1) HK1210473A1 (pt)
WO (1) WO2014039484A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2881844A1 (en) * 2012-09-07 2014-03-13 Zoetis Llc Spirocyclic derivatives as antiparasitic agents
WO2014189837A1 (en) * 2013-05-20 2014-11-27 Zoetis Llc Long-acting spiro-isoxazoline antiparasitic compositions
KR20170102359A (ko) * 2015-01-16 2017-09-08 아비스타 파마 솔루션즈, 아이엔씨. 항기생충 화합물
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
CN108055825B (zh) 2015-04-08 2021-03-30 勃林格殷格翰动物保健美国公司 包含异噁唑啉活性剂的延长释放可注射制剂、其方法和用途
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
EP3426660A1 (en) * 2016-03-09 2019-01-16 Basf Se Spirocyclic derivatives
US20190082696A1 (en) * 2016-03-11 2019-03-21 Basf Se Method for controlling pests of plants
WO2017201134A1 (en) * 2016-05-20 2017-11-23 Avista Pharma Solutions, Inc. Synthetic process and novel intermediates
US20200181134A1 (en) * 2016-07-08 2020-06-11 Avista Phama Solutions, Inc. Antiparasitic Compounds
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
AU2017344097A1 (en) 2016-10-14 2019-05-02 Boehringer Ingelheim Animal Health USA Inc. Pesticidal and parasiticidal vinyl isoxazoline compounds
US11589586B2 (en) 2017-08-14 2023-02-28 Boehringer Ingelheim Animal Health USA Inc. Pesticidal and parasiticidal pyrazole-isoxazoline compounds
CN111253331B (zh) * 2020-03-17 2022-03-08 南京林业大学 一种以二氢查尔酮为原料合成螺异噁唑啉的方法
WO2021242481A1 (en) 2020-05-28 2021-12-02 Boehringer Ingelheim Animal Health USA Inc. Bi-modal release intra-ruminal capsule device and methods of use thereof
EP4262789A1 (en) 2020-12-21 2023-10-25 Boehringer Ingelheim Vetmedica GmbH Parasiticidal collar comprising isoxazoline compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101197482B1 (ko) * 2004-03-05 2012-11-09 닛산 가가쿠 고교 가부시키 가이샤 이속사졸린 치환 벤즈아미드 화합물 및 유해생물 방제제
WO2007105814A1 (ja) * 2006-03-10 2007-09-20 Nissan Chemical Industries, Ltd. 置換イソキサゾリン化合物及び有害生物防除剤
AU2009289711A1 (en) * 2008-09-04 2010-03-11 Syngenta Limited Insecticidal compounds
US20110288089A1 (en) * 2009-01-22 2011-11-24 Syngenta Crop Protection Llc Insecticidal compounds
KR101508862B1 (ko) * 2010-08-05 2015-04-07 조에티스 엘엘씨 구충제로서 이속사졸린 유도체
CA2828397C (en) * 2011-03-10 2015-10-13 Zoetis Llc Spirocyclic isoxazoline derivatives as antiparasitic agents

Also Published As

Publication number Publication date
EP2892901A1 (en) 2015-07-15
CA2882546A1 (en) 2014-03-13
US9131697B2 (en) 2015-09-15
US20150181882A1 (en) 2015-07-02
CN104603140A (zh) 2015-05-06
AU2013312891A1 (en) 2015-02-26
WO2014039484A1 (en) 2014-03-13
HK1210473A1 (en) 2016-04-22

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Legal Events

Date Code Title Description
B08F Application fees: dismissal - article 86 of industrial property law
B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)