BR112015002083A2 - método para a determinação da afinidade de ligação de uma droga - Google Patents
método para a determinação da afinidade de ligação de uma drogaInfo
- Publication number
- BR112015002083A2 BR112015002083A2 BR112015002083A BR112015002083A BR112015002083A2 BR 112015002083 A2 BR112015002083 A2 BR 112015002083A2 BR 112015002083 A BR112015002083 A BR 112015002083A BR 112015002083 A BR112015002083 A BR 112015002083A BR 112015002083 A2 BR112015002083 A2 BR 112015002083A2
- Authority
- BR
- Brazil
- Prior art keywords
- drug
- determining
- binding affinity
- affinity
- binding
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/557—Immunoassay; Biospecific binding assay; Materials therefor using kinetic measurement, i.e. time rate of progress of an antigen-antibody interaction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12179742 | 2012-08-08 | ||
| PCT/EP2013/066265 WO2014023655A1 (en) | 2012-08-08 | 2013-08-02 | Immunoassay-based determination of in-solution binding kinetics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112015002083A2 true BR112015002083A2 (pt) | 2017-07-04 |
Family
ID=48916046
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112015002083A BR112015002083A2 (pt) | 2012-08-08 | 2013-08-02 | método para a determinação da afinidade de ligação de uma droga |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US20150168396A1 (pt) |
| EP (1) | EP2883051B1 (pt) |
| JP (1) | JP6336980B2 (pt) |
| KR (1) | KR20150039769A (pt) |
| CN (1) | CN104541168B (pt) |
| BR (1) | BR112015002083A2 (pt) |
| CA (1) | CA2876455A1 (pt) |
| HK (1) | HK1209487A1 (pt) |
| MX (1) | MX2015001202A (pt) |
| RU (1) | RU2648521C2 (pt) |
| WO (1) | WO2014023655A1 (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2883051B1 (en) * | 2012-08-08 | 2017-09-20 | F. Hoffmann-La Roche AG | Immunoassay-based determination of in-solution binding kinetics |
| US9498233B2 (en) | 2013-03-13 | 2016-11-22 | Biomet Manufacturing, Llc. | Universal acetabular guide and associated hardware |
| KR101829450B1 (ko) | 2016-01-15 | 2018-02-20 | 한국과학기술원 | 유전자 비정상 발현 모드의 규명을 통한 약물 표적적합(drug-targetable) 유전자를 평가하는 방법 |
| EP4165409A1 (en) | 2020-06-16 | 2023-04-19 | F. Hoffmann-La Roche AG | Method for determining the free antigen of an antibody in a sample |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6057160A (en) * | 1997-08-06 | 2000-05-02 | Washington State University Research Foundation | Methods for preparation and use of a coomassie brilliant blue/protein complex |
| RU2009102155A (ru) * | 2006-06-30 | 2010-08-10 | Апплера Корпорейшн (Us) | Способы анализирования связывающих взаимодействий |
| CN101173923B (zh) * | 2007-09-27 | 2011-09-14 | 广州益善生物技术有限公司 | 一种检测抗体亲和力的方法 |
| WO2011038301A2 (en) * | 2009-09-25 | 2011-03-31 | Xoma Technology Ltd. | Screening methods |
| AU2011210840B2 (en) * | 2010-01-27 | 2014-12-11 | Massachusetts Institute Of Technology | Engineered polypeptide agents for targeted broad spectrum influenza neutralization |
| EP2823310B1 (en) | 2012-03-08 | 2018-06-20 | F.Hoffmann-La Roche Ag | Multiplexed chromatography-immunoassay method for the characterization of circulating immune complexes |
| EP2883051B1 (en) * | 2012-08-08 | 2017-09-20 | F. Hoffmann-La Roche AG | Immunoassay-based determination of in-solution binding kinetics |
-
2013
- 2013-08-02 EP EP13745066.4A patent/EP2883051B1/en active Active
- 2013-08-02 KR KR20157003358A patent/KR20150039769A/ko not_active Application Discontinuation
- 2013-08-02 CA CA2876455A patent/CA2876455A1/en not_active Abandoned
- 2013-08-02 RU RU2015105038A patent/RU2648521C2/ru not_active IP Right Cessation
- 2013-08-02 MX MX2015001202A patent/MX2015001202A/es unknown
- 2013-08-02 US US14/419,984 patent/US20150168396A1/en not_active Abandoned
- 2013-08-02 CN CN201380041606.3A patent/CN104541168B/zh active Active
- 2013-08-02 WO PCT/EP2013/066265 patent/WO2014023655A1/en active Application Filing
- 2013-08-02 JP JP2015525837A patent/JP6336980B2/ja active Active
- 2013-08-02 BR BR112015002083A patent/BR112015002083A2/pt not_active IP Right Cessation
-
2015
- 2015-10-20 HK HK15110304.3A patent/HK1209487A1/xx unknown
-
2019
- 2019-07-10 US US16/508,254 patent/US11892448B2/en active Active
-
2023
- 2023-11-29 US US18/523,859 patent/US20240102999A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20150168396A1 (en) | 2015-06-18 |
| MX2015001202A (es) | 2015-04-14 |
| HK1209487A1 (en) | 2016-04-01 |
| EP2883051A1 (en) | 2015-06-17 |
| CN104541168B (zh) | 2017-04-26 |
| CN104541168A (zh) | 2015-04-22 |
| RU2648521C2 (ru) | 2018-03-26 |
| EP2883051B1 (en) | 2017-09-20 |
| RU2015105038A (ru) | 2016-09-27 |
| US20200173989A1 (en) | 2020-06-04 |
| KR20150039769A (ko) | 2015-04-13 |
| CA2876455A1 (en) | 2014-02-13 |
| US20240102999A1 (en) | 2024-03-28 |
| WO2014023655A1 (en) | 2014-02-13 |
| JP2015525886A (ja) | 2015-09-07 |
| US11892448B2 (en) | 2024-02-06 |
| JP6336980B2 (ja) | 2018-06-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06I | Publication of requirement cancelled [chapter 6.9 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA. |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2525 DE 28-05-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |