BR112015002083A2 - método para a determinação da afinidade de ligação de uma droga - Google Patents

método para a determinação da afinidade de ligação de uma droga

Info

Publication number
BR112015002083A2
BR112015002083A2 BR112015002083A BR112015002083A BR112015002083A2 BR 112015002083 A2 BR112015002083 A2 BR 112015002083A2 BR 112015002083 A BR112015002083 A BR 112015002083A BR 112015002083 A BR112015002083 A BR 112015002083A BR 112015002083 A2 BR112015002083 A2 BR 112015002083A2
Authority
BR
Brazil
Prior art keywords
drug
determining
binding affinity
affinity
binding
Prior art date
Application number
BR112015002083A
Other languages
English (en)
Inventor
Jordan Gregor
Staack Roland
Dahl Uwe
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR112015002083A2 publication Critical patent/BR112015002083A2/pt

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/557Immunoassay; Biospecific binding assay; Materials therefor using kinetic measurement, i.e. time rate of progress of an antigen-antibody interaction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15Medicinal preparations ; Physical properties thereof, e.g. dissolubility

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
BR112015002083A 2012-08-08 2013-08-02 método para a determinação da afinidade de ligação de uma droga BR112015002083A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12179742 2012-08-08
PCT/EP2013/066265 WO2014023655A1 (en) 2012-08-08 2013-08-02 Immunoassay-based determination of in-solution binding kinetics

Publications (1)

Publication Number Publication Date
BR112015002083A2 true BR112015002083A2 (pt) 2017-07-04

Family

ID=48916046

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015002083A BR112015002083A2 (pt) 2012-08-08 2013-08-02 método para a determinação da afinidade de ligação de uma droga

Country Status (11)

Country Link
US (3) US20150168396A1 (pt)
EP (1) EP2883051B1 (pt)
JP (1) JP6336980B2 (pt)
KR (1) KR20150039769A (pt)
CN (1) CN104541168B (pt)
BR (1) BR112015002083A2 (pt)
CA (1) CA2876455A1 (pt)
HK (1) HK1209487A1 (pt)
MX (1) MX2015001202A (pt)
RU (1) RU2648521C2 (pt)
WO (1) WO2014023655A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2883051B1 (en) * 2012-08-08 2017-09-20 F. Hoffmann-La Roche AG Immunoassay-based determination of in-solution binding kinetics
US9498233B2 (en) 2013-03-13 2016-11-22 Biomet Manufacturing, Llc. Universal acetabular guide and associated hardware
KR101829450B1 (ko) 2016-01-15 2018-02-20 한국과학기술원 유전자 비정상 발현 모드의 규명을 통한 약물 표적적합(drug-targetable) 유전자를 평가하는 방법
EP4165409A1 (en) 2020-06-16 2023-04-19 F. Hoffmann-La Roche AG Method for determining the free antigen of an antibody in a sample

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6057160A (en) * 1997-08-06 2000-05-02 Washington State University Research Foundation Methods for preparation and use of a coomassie brilliant blue/protein complex
RU2009102155A (ru) * 2006-06-30 2010-08-10 Апплера Корпорейшн (Us) Способы анализирования связывающих взаимодействий
CN101173923B (zh) * 2007-09-27 2011-09-14 广州益善生物技术有限公司 一种检测抗体亲和力的方法
WO2011038301A2 (en) * 2009-09-25 2011-03-31 Xoma Technology Ltd. Screening methods
AU2011210840B2 (en) * 2010-01-27 2014-12-11 Massachusetts Institute Of Technology Engineered polypeptide agents for targeted broad spectrum influenza neutralization
EP2823310B1 (en) 2012-03-08 2018-06-20 F.Hoffmann-La Roche Ag Multiplexed chromatography-immunoassay method for the characterization of circulating immune complexes
EP2883051B1 (en) * 2012-08-08 2017-09-20 F. Hoffmann-La Roche AG Immunoassay-based determination of in-solution binding kinetics

Also Published As

Publication number Publication date
US20150168396A1 (en) 2015-06-18
MX2015001202A (es) 2015-04-14
HK1209487A1 (en) 2016-04-01
EP2883051A1 (en) 2015-06-17
CN104541168B (zh) 2017-04-26
CN104541168A (zh) 2015-04-22
RU2648521C2 (ru) 2018-03-26
EP2883051B1 (en) 2017-09-20
RU2015105038A (ru) 2016-09-27
US20200173989A1 (en) 2020-06-04
KR20150039769A (ko) 2015-04-13
CA2876455A1 (en) 2014-02-13
US20240102999A1 (en) 2024-03-28
WO2014023655A1 (en) 2014-02-13
JP2015525886A (ja) 2015-09-07
US11892448B2 (en) 2024-02-06
JP6336980B2 (ja) 2018-06-06

Similar Documents

Publication Publication Date Title
BR112014020304A8 (pt) terapêutica para ligação de eritrócitos
BR112014021742A2 (pt) métodos para determinar opticamente uma característica de uma substância
BR112014021741A2 (pt) métodos para determinar opticamente uma característica de uma substância
BR112014029231A2 (pt) método para o fracionamento da lignina
BR112014021740A2 (pt) dispositivos para determinar opticamente de uma característica de uma substância
DK3181128T3 (da) Farmaceutisk nilotinib-sammensætning
DK2857420T3 (da) Målvævsspecifikt antigenbindende molekyle
DK2694038T3 (da) Farmaceutisk sammensætning
DK2812000T3 (da) Flerlaget nikotinholdig farmaceutisk sammensætning
BR112012029866A2 (pt) método para a determinação da presença de uma proteína steap-1
FR2998303B1 (fr) Composition lubrifiante
FI20125875A (fi) Jarru
DK2897594T3 (da) Farmaceutisk sammensætning
FR2987086B1 (fr) Joint lineaire de plateforme inter-aubes
BR112014016744A8 (pt) agentes de ligação para moléculas-alvo intracelulares
BR112015001205A2 (pt) método para a fabricação de uma parte de metal.
BR112014024458A2 (pt) método para identificar uma composição líquida.
BR112014020602A2 (pt) método para a fabricação de uma composição de imunoglobulina igg enriquecida
BR112015000665A2 (pt) método para a determinação da quantidade de um anticorpo
DK3915659T3 (da) Affinitetsstøtte
FR2992655B1 (fr) Composition lubrifiante
ES2721400T8 (es) Composición de Diclofenaco
DK2855645T3 (da) Smøreoliesammensætning
ES2641042T8 (es) Procedimiento para la fabricación de un fármaco proteínico
BR112014014285A2 (pt) composição, e, método para fabricar uma composição

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA.

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2525 DE 28-05-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.