BR112014032198A2 - 1,1'-[[(alquil substituído)imino]bis(alquileno)]bis-ferrocenos e seus usos em ensaios electroquímicos por marcação de substratos de interesse - Google Patents
1,1'-[[(alquil substituído)imino]bis(alquileno)]bis-ferrocenos e seus usos em ensaios electroquímicos por marcação de substratos de interesseInfo
- Publication number
- BR112014032198A2 BR112014032198A2 BR112014032198A BR112014032198A BR112014032198A2 BR 112014032198 A2 BR112014032198 A2 BR 112014032198A2 BR 112014032198 A BR112014032198 A BR 112014032198A BR 112014032198 A BR112014032198 A BR 112014032198A BR 112014032198 A2 BR112014032198 A2 BR 112014032198A2
- Authority
- BR
- Brazil
- Prior art keywords
- bis
- ferrocenes
- imino
- alkylene
- substituted alkyl
- Prior art date
Links
- 239000000758 substrate Substances 0.000 title abstract 4
- 238000007812 electrochemical assay Methods 0.000 title abstract 3
- 125000002947 alkylene group Chemical group 0.000 title abstract 2
- 125000001841 imino group Chemical group [H]N=* 0.000 title abstract 2
- 238000002372 labelling Methods 0.000 title abstract 2
- 125000000547 substituted alkyl group Chemical group 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000006850 spacer group Chemical group 0.000 abstract 3
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000000058 cyclopentadienyl group Chemical group C1(=CC=CC1)* 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 125000003709 fluoroalkyl group Chemical group 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 1
- 125000005647 linker group Chemical group 0.000 abstract 1
- 125000001181 organosilyl group Chemical group [SiH3]* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 239000011574 phosphorus Substances 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F17/00—Metallocenes
- C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Furan Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1211157.1A GB201211157D0 (en) | 2012-06-22 | 2012-06-22 | Novel compounds and their use in analytical methods |
PCT/GB2013/051643 WO2013190328A1 (en) | 2012-06-22 | 2013-06-21 | 1,1 '-[[(substituted alkyl)imino]bis(alkylene)]bis-ferrocenes and their use in i electrochemical assays by labelling substrates of interest |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112014032198A2 true BR112014032198A2 (pt) | 2017-06-27 |
Family
ID=46704099
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014032198A BR112014032198A2 (pt) | 2012-06-22 | 2013-06-21 | 1,1'-[[(alquil substituído)imino]bis(alquileno)]bis-ferrocenos e seus usos em ensaios electroquímicos por marcação de substratos de interesse |
Country Status (11)
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201021896D0 (en) | 2010-12-22 | 2011-02-02 | Atlas Genetics Ltd | Novel compounds and their use in analytical methods |
GB201211157D0 (en) | 2012-06-22 | 2012-08-08 | Atlas Genetics Ltd | Novel compounds and their use in analytical methods |
GB201312995D0 (en) | 2013-07-19 | 2013-09-04 | Atlas Genetics Ltd | Methods and kits for specific nucleic acid amplification and detection |
GB2516672B (en) | 2013-07-29 | 2015-05-20 | Atlas Genetics Ltd | A system and method for expelling liquid from a fluidic cartridge |
GB2516675A (en) | 2013-07-29 | 2015-02-04 | Atlas Genetics Ltd | A valve which depressurises, and a valve system |
GB2516669B (en) | 2013-07-29 | 2015-09-09 | Atlas Genetics Ltd | A method for processing a liquid sample in a fluidic cartridge |
GB2516666B (en) | 2013-07-29 | 2015-09-09 | Atlas Genetics Ltd | Fluidic cartridge for nucleic acid amplification and detection |
GB2516667A (en) | 2013-07-29 | 2015-02-04 | Atlas Genetics Ltd | An improved cartridge, cartridge reader and method for preventing reuse |
CA2924750A1 (en) * | 2013-10-08 | 2015-04-16 | Atlas Genetics Limited | Labelling compounds and their use in assays |
GB201416459D0 (en) | 2014-09-17 | 2014-10-29 | Atlas Genetics Ltd | Detection method |
GB201501705D0 (en) | 2015-02-02 | 2015-03-18 | Atlas Genetics Ltd | Instrument for performing a diagnostic test on a fluidic cartridge |
GB2531615B (en) | 2015-02-02 | 2017-11-22 | Atlas Genetics Ltd | Instrument for performing a diagnostic test on a fluidic cartridge |
GB2531616B (en) | 2015-02-02 | 2017-11-22 | Atlas Genetics Ltd | Instrument for performing a diagnostic test on a fluidic cartridge |
CN107827936B (zh) * | 2017-11-23 | 2019-10-29 | 南京工业大学 | 二茂铁硒醚衍生物的制备及其应用 |
CN114349800B (zh) * | 2021-12-08 | 2023-08-15 | 深圳清华大学研究院 | 一种二茂铁衍生物及其合成方法和应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0820460B1 (en) * | 1995-04-11 | 1999-07-28 | Novartis AG | Dihalogenated ferrocenes and processes for the preparation thereof |
GB0205455D0 (en) * | 2002-03-07 | 2002-04-24 | Molecular Sensing Plc | Nucleic acid probes, their synthesis and use |
GB0316075D0 (en) * | 2003-07-09 | 2003-08-13 | Molecular Sensing Plc | Protease detection assay |
CA2605434A1 (en) * | 2005-04-28 | 2006-11-02 | Solvias Ag | Multiply substituted ferrocenes |
GB0922097D0 (en) * | 2009-12-17 | 2010-02-03 | Atlas Genetics Ltd | Microbial assay |
GB201021896D0 (en) | 2010-12-22 | 2011-02-02 | Atlas Genetics Ltd | Novel compounds and their use in analytical methods |
GB201211157D0 (en) * | 2012-06-22 | 2012-08-08 | Atlas Genetics Ltd | Novel compounds and their use in analytical methods |
-
2012
- 2012-06-22 GB GBGB1211157.1A patent/GB201211157D0/en not_active Ceased
-
2013
- 2013-06-21 CA CA2877220A patent/CA2877220A1/en not_active Abandoned
- 2013-06-21 EA EA201590067A patent/EA201590067A1/ru unknown
- 2013-06-21 EP EP13731474.6A patent/EP2864342B1/en active Active
- 2013-06-21 ES ES13731474T patent/ES2895525T3/es active Active
- 2013-06-21 EP EP21188839.1A patent/EP3974435B1/en active Active
- 2013-06-21 JP JP2015517861A patent/JP2015521616A/ja active Pending
- 2013-06-21 AU AU2013279049A patent/AU2013279049B2/en not_active Ceased
- 2013-06-21 US US14/410,296 patent/US20150293107A1/en not_active Abandoned
- 2013-06-21 WO PCT/GB2013/051643 patent/WO2013190328A1/en active Application Filing
- 2013-06-21 BR BR112014032198A patent/BR112014032198A2/pt not_active Application Discontinuation
- 2013-06-21 CN CN201380043830.6A patent/CN104781269B/zh not_active Expired - Fee Related
-
2018
- 2018-02-27 US US15/906,241 patent/US10502744B2/en active Active
- 2018-06-19 US US16/012,219 patent/US10613095B2/en active Active
-
2019
- 2019-10-25 US US16/664,306 patent/US10837967B2/en active Active
-
2020
- 2020-11-16 US US17/099,290 patent/US11808768B2/en active Active
-
2023
- 2023-10-12 US US18/485,575 patent/US12111320B2/en active Active
-
2024
- 2024-10-07 US US18/907,877 patent/US20250044297A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US10502744B2 (en) | 2019-12-10 |
US20250044297A1 (en) | 2025-02-06 |
EP2864342B1 (en) | 2021-08-04 |
EA201590067A1 (ru) | 2015-06-30 |
CN104781269A (zh) | 2015-07-15 |
EP2864342A1 (en) | 2015-04-29 |
GB201211157D0 (en) | 2012-08-08 |
US12111320B2 (en) | 2024-10-08 |
US10613095B2 (en) | 2020-04-07 |
JP2015521616A (ja) | 2015-07-30 |
CN104781269B (zh) | 2017-12-22 |
CA2877220A1 (en) | 2013-12-27 |
ES2895525T3 (es) | 2022-02-21 |
AU2013279049A1 (en) | 2015-01-22 |
US20150293107A1 (en) | 2015-10-15 |
US20180252723A1 (en) | 2018-09-06 |
US20210116457A1 (en) | 2021-04-22 |
EP3974435A1 (en) | 2022-03-30 |
US20180299454A1 (en) | 2018-10-18 |
WO2013190328A1 (en) | 2013-12-27 |
US11808768B2 (en) | 2023-11-07 |
US20200057071A1 (en) | 2020-02-20 |
US10837967B2 (en) | 2020-11-17 |
AU2013279049B2 (en) | 2017-11-23 |
EP3974435B1 (en) | 2023-12-27 |
US20240060984A1 (en) | 2024-02-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |