BR112014028618A2 - veliparib em combinação com terapia de radiação cerebral total para o tratamento de metástases cerebrais. - Google Patents

veliparib em combinação com terapia de radiação cerebral total para o tratamento de metástases cerebrais.

Info

Publication number
BR112014028618A2
BR112014028618A2 BR112014028618A BR112014028618A BR112014028618A2 BR 112014028618 A2 BR112014028618 A2 BR 112014028618A2 BR 112014028618 A BR112014028618 A BR 112014028618A BR 112014028618 A BR112014028618 A BR 112014028618A BR 112014028618 A2 BR112014028618 A2 BR 112014028618A2
Authority
BR
Brazil
Prior art keywords
brain
veliparib
treatment
combination
radiation therapy
Prior art date
Application number
BR112014028618A
Other languages
English (en)
Inventor
Louis Giranda Vincent
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48576528&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112014028618(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of BR112014028618A2 publication Critical patent/BR112014028618A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092—Details
    • A61N2005/1098—Enhancing the effect of the particle by an injected agent or implanted device

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BR112014028618A 2012-05-15 2013-05-15 veliparib em combinação com terapia de radiação cerebral total para o tratamento de metástases cerebrais. BR112014028618A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261647329P 2012-05-15 2012-05-15
PCT/US2013/041095 WO2013173428A1 (en) 2012-05-15 2013-05-15 Veliparib in combination with whole brain radiation therapy for the treatment of brain metastases

Publications (1)

Publication Number Publication Date
BR112014028618A2 true BR112014028618A2 (pt) 2017-06-27

Family

ID=48576528

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014028618A BR112014028618A2 (pt) 2012-05-15 2013-05-15 veliparib em combinação com terapia de radiação cerebral total para o tratamento de metástases cerebrais.

Country Status (18)

Country Link
US (1) US20130310625A1 (pt)
EP (1) EP2849750A1 (pt)
JP (1) JP2015521188A (pt)
KR (1) KR20150017355A (pt)
CN (1) CN104602688A (pt)
AU (1) AU2013262906A1 (pt)
BR (1) BR112014028618A2 (pt)
CA (1) CA2873119A1 (pt)
CL (1) CL2014003072A1 (pt)
DO (1) DOP2014000258A (pt)
HK (1) HK1207984A1 (pt)
IL (1) IL235389A0 (pt)
MX (1) MX2014013903A (pt)
PH (1) PH12014502464A1 (pt)
RU (1) RU2014150506A (pt)
SG (1) SG11201407498RA (pt)
TW (1) TW201400113A (pt)
WO (1) WO2013173428A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107073015B (zh) * 2014-09-16 2020-07-21 艾伯维公司 用于治疗吸烟者中的非小细胞肺癌的维利帕尼与卡铂和紫杉醇的组合

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI375673B (en) 2005-04-11 2012-11-01 Abbott Lab 1h-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position are potent parp inhibitors
US20070265324A1 (en) 2006-01-17 2007-11-15 Wolfgang Wernet Combination Therapy with Parp Inhibitors
US20130030237A1 (en) * 2010-04-15 2013-01-31 Charles Theuer Potentiation of anti-cancer activity through combination therapy with ber pathway inhibitors

Also Published As

Publication number Publication date
PH12014502464A1 (en) 2014-12-22
IL235389A0 (en) 2014-12-31
MX2014013903A (es) 2015-01-16
CL2014003072A1 (es) 2015-02-27
WO2013173428A1 (en) 2013-11-21
AU2013262906A1 (en) 2014-11-20
SG11201407498RA (en) 2014-12-30
JP2015521188A (ja) 2015-07-27
KR20150017355A (ko) 2015-02-16
US20130310625A1 (en) 2013-11-21
EP2849750A1 (en) 2015-03-25
CA2873119A1 (en) 2013-11-21
RU2014150506A (ru) 2016-07-10
DOP2014000258A (es) 2015-01-15
HK1207984A1 (en) 2016-02-19
TW201400113A (zh) 2014-01-01
CN104602688A (zh) 2015-05-06

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]