BR112014015405A2 - novo anticorpo ctgf anti-humano - Google Patents
novo anticorpo ctgf anti-humanoInfo
- Publication number
- BR112014015405A2 BR112014015405A2 BR112014015405A BR112014015405A BR112014015405A2 BR 112014015405 A2 BR112014015405 A2 BR 112014015405A2 BR 112014015405 A BR112014015405 A BR 112014015405A BR 112014015405 A BR112014015405 A BR 112014015405A BR 112014015405 A2 BR112014015405 A2 BR 112014015405A2
- Authority
- BR
- Brazil
- Prior art keywords
- human ctgf
- ctgf antibody
- human
- antibody
- amino acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011281811 | 2011-12-22 | ||
| PCT/JP2012/083206 WO2013094723A1 (ja) | 2011-12-22 | 2012-12-21 | 新規抗ヒトｃｔｇｆ抗体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112014015405A2 true BR112014015405A2 (pt) | 2017-06-13 |
Family
ID=48668601
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014015405A BR112014015405A2 (pt) | 2011-12-22 | 2012-12-21 | novo anticorpo ctgf anti-humano |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US9587015B2 (https=) |
| EP (1) | EP2796550B1 (https=) |
| JP (1) | JP6040943B2 (https=) |
| KR (1) | KR20140107507A (https=) |
| CN (1) | CN104011206B (https=) |
| AR (1) | AR089425A1 (https=) |
| BR (1) | BR112014015405A2 (https=) |
| CA (1) | CA2859627A1 (https=) |
| EA (1) | EA029290B1 (https=) |
| ES (1) | ES2665851T3 (https=) |
| IN (1) | IN2014CN04615A (https=) |
| MX (1) | MX345019B (https=) |
| PL (1) | PL2796550T3 (https=) |
| PT (1) | PT2796550T (https=) |
| TW (1) | TW201333034A (https=) |
| WO (1) | WO2013094723A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109824777A (zh) * | 2019-03-15 | 2019-05-31 | 辽宁何氏医学院 | 一种具有抑制玻璃体视网膜纤维化病变作用的单克隆抗体及其制备方法和应用 |
| US20200369759A1 (en) | 2019-05-23 | 2020-11-26 | Fibrogen, Inc. | Methods of treatment of muscular dystrophies |
| KR20220016890A (ko) * | 2019-06-04 | 2022-02-10 | 지앙수 헨그루이 메디슨 컴퍼니 리미티드 | 항-결합조직 성장인자 항체 및 이의 응용 |
| CN116391041A (zh) * | 2020-12-03 | 2023-07-04 | 江苏恒瑞医药股份有限公司 | 一种含抗结缔组织生长因子抗体的药物组合物 |
| JPWO2023238845A1 (https=) | 2022-06-07 | 2023-12-14 | ||
| AU2023373601A1 (en) | 2022-10-31 | 2025-04-03 | Astellas Pharma Inc. | Antibody-drug conjugate containing a toll-like receptor 7/8 dual agonist compound |
| WO2024188179A1 (zh) * | 2023-03-10 | 2024-09-19 | 上海济煜医药科技有限公司 | 一种靶向ctgf的抗体或其抗原结合片段及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE8808645U1 (de) | 1988-07-06 | 1988-08-25 | Hofer, Daniel, 7730 Villingen-Schwenningen | Anzeigeeinrichtung für Feuerlöscher |
| KR100337069B1 (ko) | 1993-03-11 | 2002-10-11 | 사이단호진가가쿠오요비겟세이리요호오겐큐쇼 | 항-hiv모노클로날항체 |
| JP4537507B2 (ja) * | 1997-12-25 | 2010-09-01 | アムジェン インコーポレイテッド | 結合組織増殖因子に対するモノクローナル抗体及びその医薬用途 |
| AU1682699A (en) | 1997-12-25 | 1999-07-19 | Japan Tobacco Inc. | Monoclonal antibody against connective tissue growth factor and medicinal uses thereof |
| US7115390B1 (en) | 1998-12-14 | 2006-10-03 | Fibrogen, Inc. | Connective tissue growth factor fragments and methods and uses thereof |
| CN1170849C (zh) | 1998-12-14 | 2004-10-13 | 迈阿密大学 | 结缔组织生长因子片段及其方法和用途 |
| US6596541B2 (en) | 2000-10-31 | 2003-07-22 | Regeneron Pharmaceuticals, Inc. | Methods of modifying eukaryotic cells |
| US7405274B2 (en) | 2003-06-04 | 2008-07-29 | Fibrogen, Inc. | Connective tissue growth factor antibodies |
| JP2009067678A (ja) | 2005-12-07 | 2009-04-02 | Nihon Nosan Kogyo Kk | 結合組織増殖因子に対する抗体又はそれを含む組成物 |
| US7608693B2 (en) * | 2006-10-02 | 2009-10-27 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human IL-4 receptor |
-
2012
- 2012-12-21 TW TW101148989A patent/TW201333034A/zh unknown
- 2012-12-21 US US14/367,081 patent/US9587015B2/en not_active Expired - Fee Related
- 2012-12-21 PT PT128607421T patent/PT2796550T/pt unknown
- 2012-12-21 ES ES12860742.1T patent/ES2665851T3/es active Active
- 2012-12-21 AR ARP120104933A patent/AR089425A1/es unknown
- 2012-12-21 CN CN201280063995.5A patent/CN104011206B/zh not_active Expired - Fee Related
- 2012-12-21 KR KR1020147020039A patent/KR20140107507A/ko not_active Abandoned
- 2012-12-21 CA CA2859627A patent/CA2859627A1/en not_active Abandoned
- 2012-12-21 PL PL12860742T patent/PL2796550T3/pl unknown
- 2012-12-21 EP EP12860742.1A patent/EP2796550B1/en active Active
- 2012-12-21 EA EA201491240A patent/EA029290B1/ru not_active IP Right Cessation
- 2012-12-21 WO PCT/JP2012/083206 patent/WO2013094723A1/ja not_active Ceased
- 2012-12-21 MX MX2014007681A patent/MX345019B/es active IP Right Grant
- 2012-12-21 IN IN4615CHN2014 patent/IN2014CN04615A/en unknown
- 2012-12-21 BR BR112014015405A patent/BR112014015405A2/pt unknown
- 2012-12-21 JP JP2013550349A patent/JP6040943B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AR089425A1 (es) | 2014-08-20 |
| MX2014007681A (es) | 2014-11-25 |
| ES2665851T3 (es) | 2018-04-27 |
| IN2014CN04615A (https=) | 2015-09-18 |
| EA201491240A1 (ru) | 2014-11-28 |
| WO2013094723A1 (ja) | 2013-06-27 |
| EP2796550A4 (en) | 2015-08-19 |
| EA029290B1 (ru) | 2018-03-30 |
| EP2796550B1 (en) | 2018-02-28 |
| JP6040943B2 (ja) | 2016-12-07 |
| CN104011206B (zh) | 2017-03-08 |
| PL2796550T3 (pl) | 2018-08-31 |
| US20140343258A1 (en) | 2014-11-20 |
| US9587015B2 (en) | 2017-03-07 |
| PT2796550T (pt) | 2018-04-18 |
| KR20140107507A (ko) | 2014-09-04 |
| EP2796550A1 (en) | 2014-10-29 |
| JPWO2013094723A1 (ja) | 2015-04-27 |
| CA2859627A1 (en) | 2013-06-27 |
| CN104011206A (zh) | 2014-08-27 |
| MX345019B (es) | 2017-01-11 |
| TW201333034A (zh) | 2013-08-16 |
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