BR112014011108A2 - derivados de carboxamida e ureia à base de pirazolila substituída portando uma porção fenila substituída com um grupo contendo so2 como ligantes do receptor de vaniloides - Google Patents

derivados de carboxamida e ureia à base de pirazolila substituída portando uma porção fenila substituída com um grupo contendo so2 como ligantes do receptor de vaniloides

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Publication number
BR112014011108A2
BR112014011108A2 BR112014011108A BR112014011108A BR112014011108A2 BR 112014011108 A2 BR112014011108 A2 BR 112014011108A2 BR 112014011108 A BR112014011108 A BR 112014011108A BR 112014011108 A BR112014011108 A BR 112014011108A BR 112014011108 A2 BR112014011108 A2 BR 112014011108A2
Authority
BR
Brazil
Prior art keywords
substituted
group containing
receptor ligands
phenyl moiety
urea derivatives
Prior art date
Application number
BR112014011108A
Other languages
English (en)
Portuguese (pt)
Inventor
Lesch Bernhard
John Saunders Derek
Bahrenberg Gregor
Stockhausen Hannelore
Lee Jeewoo
Kim Myeong-Seop
Damann Nils
Frank-Foltyn Robert
Christoph Thomas
Kim Yong-Soo
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of BR112014011108A2 publication Critical patent/BR112014011108A2/pt

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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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BR112014011108A 2011-11-09 2012-11-08 derivados de carboxamida e ureia à base de pirazolila substituída portando uma porção fenila substituída com um grupo contendo so2 como ligantes do receptor de vaniloides BR112014011108A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11008927 2011-11-09
PCT/EP2012/072143 WO2013068464A1 (en) 2011-11-09 2012-11-08 Substituted pyrazolyl-based carboxamide and urea derivatives bearing a phenyl moiety substituted with an so2-containing group as vanilloid receptor ligands

Publications (1)

Publication Number Publication Date
BR112014011108A2 true BR112014011108A2 (pt) 2017-05-16

Family

ID=47143914

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014011108A BR112014011108A2 (pt) 2011-11-09 2012-11-08 derivados de carboxamida e ureia à base de pirazolila substituída portando uma porção fenila substituída com um grupo contendo so2 como ligantes do receptor de vaniloides

Country Status (13)

Country Link
EP (1) EP2776401A1 (zh)
JP (1) JP2014532744A (zh)
KR (1) KR20140091041A (zh)
CN (1) CN104066720A (zh)
AR (1) AR088799A1 (zh)
AU (1) AU2012334068A1 (zh)
BR (1) BR112014011108A2 (zh)
CA (1) CA2854424A1 (zh)
HK (1) HK1202117A1 (zh)
IN (1) IN2014KN00865A (zh)
MX (1) MX2014005233A (zh)
TW (1) TW201326135A (zh)
WO (1) WO2013068464A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3113772T3 (pl) 2014-03-07 2021-04-06 Biocryst Pharmaceuticals, Inc. Pirazole podstawiane trifluorometylem jako inhibitory ludzkiej kalikreiny osoczowej
JP6422589B2 (ja) * 2014-11-24 2018-11-14 メディフロン・ディービーティー・インコーポレイテッド バニロイド受容体リガンドiiとしての置換されたオキサゾール系およびチアゾール系カルボキサミドおよび尿素誘導体
CN114920697A (zh) * 2022-05-16 2022-08-19 河南应用技术职业学院 杂环基取代的茚满丙酰胺类化合物及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2427436E (pt) 2009-05-07 2013-03-04 Gruenenthal Gmbh Derivados aromáticos substituídos de carboxamida e ureia como ligantes de receptor de vanilóide
PE20120374A1 (es) 2009-05-07 2012-05-13 Gruenenthal Chemie Fenilureas y fenilamidas como ligandos del receptor de vanilloides

Also Published As

Publication number Publication date
KR20140091041A (ko) 2014-07-18
AR088799A1 (es) 2014-07-10
TW201326135A (zh) 2013-07-01
HK1202117A1 (zh) 2015-09-18
IN2014KN00865A (zh) 2015-10-02
MX2014005233A (es) 2014-08-22
EP2776401A1 (en) 2014-09-17
CA2854424A1 (en) 2013-05-16
AU2012334068A1 (en) 2014-05-22
WO2013068464A1 (en) 2013-05-16
CN104066720A (zh) 2014-09-24
JP2014532744A (ja) 2014-12-08

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B350 Update of information on the portal [chapter 15.35 patent gazette]