BR112014005362A2 - vacinas de tumor com nanopartículas - Google Patents

vacinas de tumor com nanopartículas

Info

Publication number
BR112014005362A2
BR112014005362A2 BR112014005362A BR112014005362A BR112014005362A2 BR 112014005362 A2 BR112014005362 A2 BR 112014005362A2 BR 112014005362 A BR112014005362 A BR 112014005362A BR 112014005362 A BR112014005362 A BR 112014005362A BR 112014005362 A2 BR112014005362 A2 BR 112014005362A2
Authority
BR
Brazil
Prior art keywords
tumor vaccines
nanoparticle tumor
nanoparticle
vaccines
tumor
Prior art date
Application number
BR112014005362A
Other languages
English (en)
Inventor
Ramilaphilip
Rademacher Thomas
Original Assignee
Immunotope Inc
Midatech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunotope Inc, Midatech Ltd filed Critical Immunotope Inc
Publication of BR112014005362A2 publication Critical patent/BR112014005362A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A61K47/6923Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being an inorganic particle, e.g. ceramic particles, silica particles, ferrite or synsorb
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A61K47/6927Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores
    • A61K47/6929Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/80Vaccine for a specifically defined cancer
    • A61K2039/86Lung

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Ceramic Engineering (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nanotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
BR112014005362A 2011-09-07 2012-09-07 vacinas de tumor com nanopartículas BR112014005362A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161531730P 2011-09-07 2011-09-07
PCT/EP2012/067579 WO2013034741A1 (en) 2011-09-07 2012-09-07 Nanoparticle tumour vaccines

Publications (1)

Publication Number Publication Date
BR112014005362A2 true BR112014005362A2 (pt) 2017-06-13

Family

ID=46970246

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014005362A BR112014005362A2 (pt) 2011-09-07 2012-09-07 vacinas de tumor com nanopartículas

Country Status (11)

Country Link
US (1) US20140248360A1 (pt)
EP (1) EP2753361A1 (pt)
JP (1) JP2014531427A (pt)
KR (1) KR20140084020A (pt)
CN (1) CN103957943A (pt)
AU (1) AU2012306258A1 (pt)
BR (1) BR112014005362A2 (pt)
CA (1) CA2847907A1 (pt)
EA (1) EA201490520A1 (pt)
MX (1) MX2014002764A (pt)
WO (1) WO2013034741A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX345883B (es) 2011-09-07 2017-02-22 Midatech Ltd Composiciones de peptidos en nanoparticulas.
WO2014046807A1 (en) * 2012-09-20 2014-03-27 Board Of Regents, The University Of Texas System Hydrophobic shielding for enhanced nanoparticle stability
US20150064107A1 (en) * 2013-09-04 2015-03-05 King's College London Imaging agent
EP2921179A1 (en) * 2014-03-17 2015-09-23 Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) Micellar nanoparticles containing antitumoral glycosides
GB201507030D0 (en) 2015-04-24 2015-06-10 Immatics Biotechnologies Gmbh Immunotherapy against lung cancers, in particular NSCLC
CN108588020B (zh) * 2018-03-30 2021-09-14 中国科学院苏州纳米技术与纳米仿生研究所 一种含有硒元素的近红外ii区量子点的新应用
WO2020250153A1 (en) * 2019-06-11 2020-12-17 Pharmaexceed S.R.L. Nanoparticles for use in the redirection against the tumour of a non-tumour-specific immune response, based on a pre-existing immunity
EP3909612A1 (en) 2020-05-12 2021-11-17 Life Science Inkubator Betriebs GmbH & Co. KG Composition of nanoparticles

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0025414D0 (en) 2000-10-16 2000-11-29 Consejo Superior Investigacion Nanoparticles
GB0313259D0 (en) 2003-06-09 2003-07-16 Consejo Superior Investigacion Magnetic nanoparticles
ES2242528B1 (es) 2004-03-25 2006-12-01 Consejo Sup. Investig. Cientificas Nanoparticulas magneticas de metales nobles.
EP1756289B1 (en) 2004-05-24 2015-01-14 Midatech Ltd. Nanoparticles comprising rna ligands
CN101123990A (zh) * 2004-10-01 2008-02-13 Mida科技有限公司 包含抗原和佐剂的纳米颗粒,和免疫原性结构
AU2005291058B2 (en) * 2004-10-01 2011-09-29 Midatech Limited Nanoparticles comprising antigens and adjuvants and immunogenic structure
EP1919507A2 (en) 2005-08-04 2008-05-14 Thomas William Rademacher Nanoparticles comprising antibacterial ligands
EP2029120B1 (en) * 2006-04-13 2011-07-27 Midatech Ltd. Nanoparticles containing three various ligands for providing immune responses against infectious agents
EP2161279A1 (en) * 2008-08-29 2010-03-10 Centre National de la Recherche Scientifique Synthetic peptides corresponding to overlapping neutralizing determinants in the CBD1 epitope induce broadly neutralizing antibodies
CN107050440B (zh) * 2009-04-01 2021-10-29 迈阿密大学 疫苗组合物和其使用方法
CA2772551A1 (en) 2009-08-26 2011-03-03 Immunotope, Inc. Cytotoxic t-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer
EP2305310A1 (en) 2009-09-25 2011-04-06 Asociación Centro de Investigación Cooperativa en Biomateriales - CIC biomaGUNE Gold -coated magnetic glyconanoparticles functionalised with proteins for use as diagnostic and therapeutic agents
TWI485245B (zh) * 2010-01-25 2015-05-21 Oncotherapy Science Inc 經修飾之melk胜肽及含此胜肽之疫苗
MX345883B (es) * 2011-09-07 2017-02-22 Midatech Ltd Composiciones de peptidos en nanoparticulas.

Also Published As

Publication number Publication date
KR20140084020A (ko) 2014-07-04
AU2012306258A1 (en) 2014-04-17
CA2847907A1 (en) 2013-03-14
WO2013034741A1 (en) 2013-03-14
MX2014002764A (es) 2014-12-04
JP2014531427A (ja) 2014-11-27
US20140248360A1 (en) 2014-09-04
EA201490520A1 (ru) 2014-09-30
CN103957943A (zh) 2014-07-30
EP2753361A1 (en) 2014-07-16

Similar Documents

Publication Publication Date Title
FR23C1020I2 (fr) Conjugues pyrrolobenzodiazepine-anticorps
SMT201600476B (it) Tenofovir alafenammide emifumarato
BR112014007603A2 (pt) métodos de tratamento do câncer
DK2906251T3 (da) Pyrrolobenzodiazepin-anti-CD22-antistofkonjugater
DK2920304T3 (da) Oligonukleotidkonjugater
DK2707030T3 (da) Cancerbehandlinger
BR112013032887A2 (pt) cateter
BR112014012880A2 (pt) tratamento imunogênico do câncer
BR112014029111A2 (pt) inalador
BR112013033974A2 (pt) terapia de combinação
DK2841054T4 (da) Injicerbart præparat
DK2760886T3 (da) Immunocytokin-kombinationsterapi
DK2668967T3 (da) Implantat
SMT201600082B (it) Vaccino pcsk9
FI20115876A0 (fi) Yhdistelmähoito
FR2975090B1 (fr) Nanoparticules autodispersantes
BR112014005362A2 (pt) vacinas de tumor com nanopartículas
DK3446714T3 (da) Anti-nucleolinmiddel-konjugerede nanopartikler
SG11201500396TA (en) Tumor vaccination
EP2876161A4 (en) VACCINE
GB201223386D0 (en) Vaccine
CO6880064A2 (es) Métodos terapéuticos
DK3536334T3 (da) Cancer stamcelle målrettede cancer vacciner
FR2975564B1 (fr) Charrue
FI20115640A0 (fi) Yhdistelmähoito

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11N Dismissal: publication cancelled [chapter 11.14 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08H Application fees: decision cancelled [chapter 8.8 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: A61K 9/14 (2006.01), A61K 39/00 (2006.01), A61K 47

B350 Update of information on the portal [chapter 15.35 patent gazette]