BR112014002631A2 - soluções antiinflamatórias estáveis para injeção - Google Patents

soluções antiinflamatórias estáveis para injeção

Info

Publication number
BR112014002631A2
BR112014002631A2 BR112014002631A BR112014002631A BR112014002631A2 BR 112014002631 A2 BR112014002631 A2 BR 112014002631A2 BR 112014002631 A BR112014002631 A BR 112014002631A BR 112014002631 A BR112014002631 A BR 112014002631A BR 112014002631 A2 BR112014002631 A2 BR 112014002631A2
Authority
BR
Brazil
Prior art keywords
injection
stable anti
inflammatory
inflammatory solutions
solutions
Prior art date
Application number
BR112014002631A
Other languages
English (en)
Other versions
BR112014002631B1 (pt
Inventor
A Demopulos Gregory
Shen Hui-Rong
R Gombotz Wayne
Original Assignee
Omeros Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47627326&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112014002631(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Omeros Corp filed Critical Omeros Corp
Publication of BR112014002631A2 publication Critical patent/BR112014002631A2/pt
Publication of BR112014002631B1 publication Critical patent/BR112014002631B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/4174Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
BR112014002631-9A 2011-08-04 2012-08-03 Formulação farmacêutica líquida estável compreendendo cetoprofeno, amitriptilina e oximetazolina BR112014002631B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161515234P 2011-08-04 2011-08-04
US61/515,234 2011-08-04
PCT/US2012/049463 WO2013020021A1 (en) 2011-08-04 2012-08-03 Stable anti-inflammatory solutions for injection

Publications (2)

Publication Number Publication Date
BR112014002631A2 true BR112014002631A2 (pt) 2017-03-07
BR112014002631B1 BR112014002631B1 (pt) 2022-04-19

Family

ID=47627326

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014002631-9A BR112014002631B1 (pt) 2011-08-04 2012-08-03 Formulação farmacêutica líquida estável compreendendo cetoprofeno, amitriptilina e oximetazolina

Country Status (21)

Country Link
US (3) US20130035362A1 (pt)
EP (1) EP2739266B1 (pt)
JP (2) JP6174579B2 (pt)
KR (1) KR101951064B1 (pt)
CN (1) CN103957886B (pt)
AR (1) AR089203A1 (pt)
AU (1) AU2012289968B2 (pt)
BR (1) BR112014002631B1 (pt)
CA (1) CA2844152C (pt)
CL (1) CL2014000267A1 (pt)
DK (1) DK2739266T3 (pt)
ES (1) ES2600153T3 (pt)
HK (1) HK1198911A1 (pt)
IL (1) IL230779B (pt)
MX (1) MX347373B (pt)
NZ (1) NZ621484A (pt)
PL (1) PL2739266T3 (pt)
PT (1) PT2739266T (pt)
RU (1) RU2635521C2 (pt)
WO (1) WO2013020021A1 (pt)
ZA (1) ZA201401344B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2968992B8 (en) 2013-03-15 2020-01-15 Tonix Pharma Holdings Limited Eutectic formulations of cyclobenzaprine hydrochloride and mannitol
WO2016014408A1 (en) * 2014-07-21 2016-01-28 Board Of Regents, The University Of Texas System Formulations of intraarticular pharmaceutical agents and methods for preparing and using the same
TWI809304B (zh) 2014-12-01 2023-07-21 奥默羅斯公司 用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液
US20170049134A1 (en) * 2015-08-18 2017-02-23 Empire Technology Development Llc Meat tendering using food grade natural products for reducing muscle contraction
JP7023690B2 (ja) 2017-12-06 2022-02-22 株式会社東芝 道路維持管理システム、道路維持管理方法及びコンピュータプログラム
US20220347122A1 (en) * 2019-03-15 2022-11-03 Ftf Pharma Private Limited Solutions for oral dosage
WO2021084730A1 (ja) 2019-11-01 2021-05-06 三菱電機株式会社 劣化状態判定装置、劣化状態検査システム、及び、劣化状態検査方法
FR3123563A1 (fr) * 2021-06-03 2022-12-09 Algotherapeutix Utilisation de l’amitriptyline et/ou l’un de ses sels pharmaceutiquement acceptable comme agent conservateur
CN116165306B (zh) * 2023-04-25 2023-11-17 湖南九典制药股份有限公司 酮洛芬凝胶贴膏中有关物质的分析测定方法及应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5624893A (en) * 1993-10-14 1997-04-29 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment of the cornea following laser irradiation
IT1269583B (it) * 1994-04-26 1997-04-08 Bayer Italia Spa Preparazioni farmaceutiche a base di una soluzione di ketoprofene in capsule di gelatina molle e metodo per la loro produzione
KR100517210B1 (ko) 1994-12-12 2006-06-07 오메로스 코포레이션 통증,염증및경련억제용관주용액
US7091181B2 (en) * 1994-12-12 2006-08-15 Omeros Corporation Method of inhibition of pain and inflammation during surgery comprising administration of soluble TNF receptors
CA2206119C (en) * 1994-12-12 2008-05-13 Omeros Medical Systems, Inc. Irrigation solution and method for inhibition of pain, inflammation and spasm
IT1277741B1 (it) * 1995-12-28 1997-11-12 Dompe Spa Composizioni farmaceutiche parenterali contenenti sali di alchilammonio di acidi 2-arilpropionici
US7973068B2 (en) * 1998-10-20 2011-07-05 Omeros Corporation Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation
US7022740B2 (en) * 2004-04-29 2006-04-04 Leonard Mackles Lubricious ophthalmic solutions
US20070053868A1 (en) * 2005-03-08 2007-03-08 Banner Pharmacaps, Inc. Solvent system for enhancing the solubility of pharmaceutical agents
WO2006127096A2 (en) * 2005-05-20 2006-11-30 Omeros Corporation Cyclooxygenase inhibitor and calcium channel antagonist compositions and methods for use in urological procedures
JP2009528382A (ja) * 2006-03-01 2009-08-06 トリストラータ・インコーポレイテッド タール応答性皮膚疾患の局所治療のための組成物及び方法
CN101677957A (zh) * 2007-02-05 2010-03-24 卡比兰生物外科公司 用于递送生物活性试剂的聚合物制剂
WO2008115572A1 (en) * 2007-03-21 2008-09-25 Theraquest Biosciences, Inc. Methods and compositions of nsaids
CN107007546A (zh) * 2011-02-15 2017-08-04 阿勒根公司 用于治疗红斑痤疮的症状的羟甲唑啉药物乳膏组合物

Also Published As

Publication number Publication date
US20160166696A1 (en) 2016-06-16
US20130035362A1 (en) 2013-02-07
ZA201401344B (en) 2016-10-26
CL2014000267A1 (es) 2014-08-29
KR101951064B1 (ko) 2019-02-21
JP2017014288A (ja) 2017-01-19
IL230779A0 (en) 2014-03-31
AU2012289968A1 (en) 2013-03-28
EP2739266A1 (en) 2014-06-11
MX347373B (es) 2017-04-25
AU2012289968B2 (en) 2014-01-16
RU2635521C2 (ru) 2017-11-13
JP6174579B2 (ja) 2017-08-02
CN103957886A (zh) 2014-07-30
ES2600153T3 (es) 2017-02-07
KR20140057579A (ko) 2014-05-13
PT2739266T (pt) 2016-10-04
EP2739266B1 (en) 2016-07-27
CA2844152A1 (en) 2013-02-07
HK1198911A1 (zh) 2015-06-19
US20180344855A1 (en) 2018-12-06
JP2014521694A (ja) 2014-08-28
CN103957886B (zh) 2016-03-30
NZ621484A (en) 2016-05-27
AR089203A1 (es) 2014-08-06
BR112014002631B1 (pt) 2022-04-19
MX2014001368A (es) 2014-06-11
IL230779B (en) 2019-05-30
EP2739266A4 (en) 2014-12-31
DK2739266T3 (en) 2016-10-03
PL2739266T3 (pl) 2017-07-31
WO2013020021A1 (en) 2013-02-07
RU2014108159A (ru) 2015-09-10
CA2844152C (en) 2020-04-14

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 03/08/2012, OBSERVADAS AS CONDICOES LEGAIS.