BR112013028406A2 - método para identificar alvos de antibióticos - Google Patents
método para identificar alvos de antibióticosInfo
- Publication number
- BR112013028406A2 BR112013028406A2 BR112013028406A BR112013028406A BR112013028406A2 BR 112013028406 A2 BR112013028406 A2 BR 112013028406A2 BR 112013028406 A BR112013028406 A BR 112013028406A BR 112013028406 A BR112013028406 A BR 112013028406A BR 112013028406 A2 BR112013028406 A2 BR 112013028406A2
- Authority
- BR
- Brazil
- Prior art keywords
- antibiotic targets
- identifying antibiotic
- identifying
- targets
- antibiotic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1082—Preparation or screening gene libraries by chromosomal integration of polynucleotide sequences, HR-, site-specific-recombination, transposons, viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/06—Methods of screening libraries by measuring effects on living organisms, tissues or cells
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/50—Mutagenesis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biochemistry (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Medical Informatics (AREA)
- Evolutionary Biology (AREA)
- Microbiology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB11075150.7 | 2011-05-05 | ||
| GBGB1107515.7A GB201107515D0 (en) | 2011-05-05 | 2011-05-05 | Method for identifying antibiotic targets |
| PCT/GB2012/000402 WO2012150432A1 (en) | 2011-05-05 | 2012-05-03 | Method for identifying antibiotic targets |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR112013028406A2 true BR112013028406A2 (pt) | 2016-09-20 |
| BR112013028406B1 BR112013028406B1 (pt) | 2021-12-07 |
| BR112013028406B8 BR112013028406B8 (pt) | 2022-03-03 |
Family
ID=44243664
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013028406A BR112013028406B8 (pt) | 2011-05-05 | 2012-05-03 | Método para identificar alvos de antibióticos |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US9745572B2 (pt) |
| EP (1) | EP2705148B1 (pt) |
| JP (1) | JP6015974B2 (pt) |
| KR (1) | KR101984324B1 (pt) |
| CN (1) | CN103687948B (pt) |
| AU (1) | AU2012251521B2 (pt) |
| BR (1) | BR112013028406B8 (pt) |
| CA (1) | CA2835133C (pt) |
| DK (1) | DK2705148T5 (pt) |
| ES (1) | ES2618207T3 (pt) |
| GB (1) | GB201107515D0 (pt) |
| PT (1) | PT2705148T (pt) |
| RU (1) | RU2630622C2 (pt) |
| SG (1) | SG194777A1 (pt) |
| WO (1) | WO2012150432A1 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201107516D0 (en) | 2011-05-05 | 2011-06-22 | Discuva Ltd | Method for identifying antibiotic targets by complemented sequencing |
| GB201107515D0 (en) | 2011-05-05 | 2011-06-22 | Discuva Ltd | Method for identifying antibiotic targets |
| GB201219989D0 (en) * | 2012-11-06 | 2012-12-19 | Discuva Ltd | Bacterial engineering |
| GB201413198D0 (en) | 2014-07-25 | 2014-09-10 | Discuva Ltd | Methods For Characterizing Bacterial Mutants |
| GB201507931D0 (en) | 2015-05-08 | 2015-06-24 | Discuva Ltd | Combination therapies for combating resistance |
| US10629291B2 (en) * | 2016-03-10 | 2020-04-21 | Koninklijke Philips N.V. | Antibiotic resistance causation identification |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2241758C2 (ru) * | 1994-12-09 | 2004-12-10 | Империал Колледж Инновейшенс Лимитед, Майкросайенс Лимитед | Способ определения микроорганизма с пониженной адаптацией к конкретной окружающей среде, днк (варианты), ген вирулентности, полипептид, способ определения соединения, антисмысловая нуклеиновая кислота, способ лечения хозяина и фармацевтическая композиция |
| IL121996A0 (en) * | 1997-10-19 | 1998-03-10 | Rosenberg Peretz | Drip irrigation devices and method of making same |
| US6207384B1 (en) * | 1998-03-27 | 2001-03-27 | The General Hospital Corporation | Systematic identification of essential genes by in vitro transposon mutagenesis |
| GB9917531D0 (en) | 1999-07-26 | 1999-09-29 | Arrow Therapeutics Ltd | Transposon mediated differential hybridisation |
| US6991900B2 (en) | 2000-06-28 | 2006-01-31 | California Institute Of Technology | Methods for identifying an essential gene in a prokaryotic microorganism |
| US20020076722A1 (en) * | 2000-09-13 | 2002-06-20 | Neyfakh Alexander A. | Antibiotic hypersusceptibility mutations in bacteria |
| KR100459870B1 (ko) | 2002-02-22 | 2004-12-04 | 한국과학기술원 | 트랜스포존과 Cre/loxP 부위 특이적 재조합 방법을 이용하는 염색체의 특정부위가 제거된 미생물 변이주 제조방법 |
| AU2003278714A1 (en) | 2002-08-20 | 2004-03-11 | Chiron Corporation | Random transposon insertion in staphylococcus aureus and use thereof to identify essential genes |
| US20100247495A1 (en) | 2009-03-30 | 2010-09-30 | Tom Ichim | Treatment of Muscular Dystrophy |
| GB201107515D0 (en) | 2011-05-05 | 2011-06-22 | Discuva Ltd | Method for identifying antibiotic targets |
| GB201107516D0 (en) | 2011-05-05 | 2011-06-22 | Discuva Ltd | Method for identifying antibiotic targets by complemented sequencing |
| GB201219989D0 (en) | 2012-11-06 | 2012-12-19 | Discuva Ltd | Bacterial engineering |
| US20160201129A1 (en) | 2013-08-26 | 2016-07-14 | President And Fellows Of Harvard College | Determination of immune cells and other cells |
| GB2505819B (en) | 2013-12-13 | 2014-10-01 | Discuva Ltd | Method for identifying genes involved in antibiotic resistance and sensitivity in gram-negative bacteria |
| GB201413202D0 (en) | 2014-07-25 | 2014-09-10 | Discuva Ltd | Process for producing bacterial mutants |
| GB201413198D0 (en) | 2014-07-25 | 2014-09-10 | Discuva Ltd | Methods For Characterizing Bacterial Mutants |
| GB201421854D0 (en) | 2014-12-09 | 2015-01-21 | Discuva Ltd | Identifying genes involved in antibiotic resistance and sensitivity in bacteria using microcultures |
| GB201421850D0 (en) | 2014-12-09 | 2015-01-21 | Bactevo Ltd | Method for screening for bioactive natural products |
-
2011
- 2011-05-05 GB GBGB1107515.7A patent/GB201107515D0/en not_active Ceased
-
2012
- 2012-05-03 BR BR112013028406A patent/BR112013028406B8/pt not_active IP Right Cessation
- 2012-05-03 CA CA2835133A patent/CA2835133C/en active Active
- 2012-05-03 ES ES12723223.9T patent/ES2618207T3/es active Active
- 2012-05-03 JP JP2014508869A patent/JP6015974B2/ja active Active
- 2012-05-03 WO PCT/GB2012/000402 patent/WO2012150432A1/en active Application Filing
- 2012-05-03 SG SG2013081641A patent/SG194777A1/en unknown
- 2012-05-03 AU AU2012251521A patent/AU2012251521B2/en active Active
- 2012-05-03 CN CN201280033343.7A patent/CN103687948B/zh active Active
- 2012-05-03 DK DK12723223.9T patent/DK2705148T5/en active
- 2012-05-03 PT PT127232239T patent/PT2705148T/pt unknown
- 2012-05-03 EP EP12723223.9A patent/EP2705148B1/en active Active
- 2012-05-03 RU RU2013149303A patent/RU2630622C2/ru active
- 2012-05-03 KR KR1020137032286A patent/KR101984324B1/ko active IP Right Grant
-
2013
- 2013-11-04 US US14/071,615 patent/US9745572B2/en active Active
-
2017
- 2017-07-20 US US15/655,784 patent/US11359195B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| BR112013028406B1 (pt) | 2021-12-07 |
| KR20140057207A (ko) | 2014-05-12 |
| US20180010122A1 (en) | 2018-01-11 |
| ES2618207T3 (es) | 2017-06-21 |
| AU2012251521B2 (en) | 2016-07-14 |
| RU2630622C2 (ru) | 2017-09-11 |
| CN103687948B (zh) | 2018-12-04 |
| WO2012150432A1 (en) | 2012-11-08 |
| GB201107515D0 (en) | 2011-06-22 |
| EP2705148B1 (en) | 2016-11-23 |
| CA2835133A1 (en) | 2012-11-08 |
| US20220186211A9 (en) | 2022-06-16 |
| EP2705148A1 (en) | 2014-03-12 |
| CN103687948A (zh) | 2014-03-26 |
| KR101984324B1 (ko) | 2019-05-30 |
| US20140141979A1 (en) | 2014-05-22 |
| DK2705148T5 (en) | 2017-03-13 |
| JP2014513961A (ja) | 2014-06-19 |
| PT2705148T (pt) | 2017-03-02 |
| DK2705148T3 (en) | 2017-02-13 |
| BR112013028406B8 (pt) | 2022-03-03 |
| WO2012150432A8 (en) | 2013-01-03 |
| US11359195B2 (en) | 2022-06-14 |
| CA2835133C (en) | 2020-05-05 |
| JP6015974B2 (ja) | 2016-10-26 |
| US9745572B2 (en) | 2017-08-29 |
| AU2012251521A1 (en) | 2013-11-21 |
| SG194777A1 (en) | 2013-12-30 |
| RU2013149303A (ru) | 2015-06-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CO6950446A2 (es) | Mecanismo y método de sellado para empalme de cable de bajada | |
| BR112014005087A2 (pt) | método para detectar nucleossomas contendo nucleotídeos | |
| DE102012208877A8 (de) | System zur Erfassung bewegter Objekte | |
| CO6910200A2 (es) | Derivado de pirazoloquinolina | |
| BR112013014703A2 (pt) | mapeamento de informação eficiente para concessões de transmissão | |
| BR112014002252A2 (pt) | métodos para a detecção de modificação de nucleotídeo | |
| BR112014000451A2 (pt) | sistemas e métodos para determinar coberturas opcionais de seguro | |
| BR112014007958A2 (pt) | método | |
| CL2015000158A1 (es) | Metodo para la manipulacion de aguacates | |
| BR112014001237A2 (pt) | método | |
| BR112014001765A2 (pt) | método | |
| BR112013030423A2 (pt) | método para produção de biocoque | |
| CO6920298A2 (es) | Método para cultivar caña de azucar | |
| EP2691542A4 (en) | SCREENING METHODS FOR IDENTIFICATION OF SPECIFIC STAPHYLOCOCCUS AUREUS INHIBITORS | |
| CU24164B1 (es) | Inhibidores sustituidos de acetil-coa carboxilasa | |
| EP2678319A4 (en) | ANTIBIOTICS TOLERANCE INHIBITORS | |
| BR112014016066A2 (pt) | método para detectar micro-organismos salmonella | |
| BR112014009795A2 (pt) | método | |
| BR112015005752A2 (pt) | método para fabricação de cilindros de gás | |
| BR112012021070A2 (pt) | método para produção de cadaverina | |
| FR2969276B1 (fr) | Machine de lancement de cibles | |
| BR112013028406A2 (pt) | método para identificar alvos de antibióticos | |
| BR112014007794A2 (pt) | método para otimização de desempenho de solda | |
| BR112014012534A2 (pt) | métodos para a preparação de hidrogéis | |
| PT2705149T (pt) | Método de identificação de alvos de antibióticos por sequenciamento complementar |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B06I | Publication of requirement cancelled [chapter 6.9 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 6.21 NA RPI NO 2614 DE 09/02/2021 POR TER SIDO INDEVIDA. |
|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B09W | Correction of the decision to grant [chapter 9.1.4 patent gazette] |
Free format text: PARECER DE DEFERIMENTO COM INCORRECAO NO QUADRO 1 DO PARECER. |
|
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 03/05/2012, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: REF. RPI 2657 DE 07/12/2021 QUANTO AO QUADRO REIVINDICATORIO. |
|
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 11A ANUIDADE. |
|
| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2721 DE 28-02-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |