BR112013026909A2 - Produtos medicinais para uso em condições correlacionadas a infecções microbianas no trato aerodigestivo superior - Google Patents

Produtos medicinais para uso em condições correlacionadas a infecções microbianas no trato aerodigestivo superior

Info

Publication number
BR112013026909A2
BR112013026909A2 BR112013026909A BR112013026909A BR112013026909A2 BR 112013026909 A2 BR112013026909 A2 BR 112013026909A2 BR 112013026909 A BR112013026909 A BR 112013026909A BR 112013026909 A BR112013026909 A BR 112013026909A BR 112013026909 A2 BR112013026909 A2 BR 112013026909A2
Authority
BR
Brazil
Prior art keywords
aerodigestive tract
upper aerodigestive
medicinal products
microbial infections
infections
Prior art date
Application number
BR112013026909A
Other languages
English (en)
Inventor
Härkönen Matti
Marvola Tuuli
Salaspuro Mikko
Suovaniemi Osmo
Original Assignee
Biohit Oyj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biohit Oyj filed Critical Biohit Oyj
Publication of BR112013026909A2 publication Critical patent/BR112013026909A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

PRODUTOS MEDICINAIS PARA USO EM CONDIÇÕES CORRELACIONADAS A INFECÇÕES MICROBIANAS NO TRATO AERODIGESTIVO SUPERIOR. A presente invenção está correlacionada a produtos, tais como, composições ou dispositivos médicos, compreendendo um ou mais compostos de Fórmula (I), contendo um ou mais grupos sulfidrila, em que: - R1 é hidrogênio ou um grupo acetila; e - R2 é um grupo sulfidrila ou uma cadeia de hidrocarboneto C1-C5 reta ou ramificada, opcionalmente, contendo um ou mais heteroátomos selecionados de O, N e S, contendo ainda um ou mais grupos sulfidrila livres; para uso em conexão com infecções causadas por Helicobacter pylori ou outras infecções correlacionadas, ditos compostos sendo usados como tais ou em mistura com antibióticos, pelo que o(s) composto(s) e, opcionalmente, o(s) antibiótico(s), quando presente(s), são misturados com um ou mais veículos farmaceuticamente aceitáveis, proporcionando uma liberação local constante no estômago ou em outro local no trato aerodigestivo superior.
BR112013026909A 2011-04-18 2012-04-18 Produtos medicinais para uso em condições correlacionadas a infecções microbianas no trato aerodigestivo superior BR112013026909A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161476335P 2011-04-18 2011-04-18
FI20115377A FI20115377A (fi) 2011-04-18 2011-04-18 Ylempien hengitys- ja ruoansulatuselinten mikrobi-infektioihin liittyvissä tiloissa käytettäväksi tarkoitettuja lääketieteellisiä tuotteita
PCT/FI2012/050377 WO2012143608A2 (en) 2011-04-18 2012-04-18 Medical products for use in conditions related to microbial infections in the upper aerodigestive tract

Publications (1)

Publication Number Publication Date
BR112013026909A2 true BR112013026909A2 (pt) 2017-10-03

Family

ID=43919696

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013026909A BR112013026909A2 (pt) 2011-04-18 2012-04-18 Produtos medicinais para uso em condições correlacionadas a infecções microbianas no trato aerodigestivo superior

Country Status (8)

Country Link
US (1) US20140128336A1 (pt)
EP (1) EP2699239A2 (pt)
JP (1) JP2014511896A (pt)
BR (1) BR112013026909A2 (pt)
CA (1) CA2831650A1 (pt)
CO (1) CO6831981A2 (pt)
FI (1) FI20115377A (pt)
WO (1) WO2012143608A2 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20135097L (fi) * 2013-02-01 2014-08-02 Biohit Oyj Koostumus aldehydien sitomiseen suussa
US20160022621A1 (en) * 2013-03-12 2016-01-28 Biohit Oyj Composition for oral administration for binding aldehydes in the gastrointestinal tract
US20160022620A1 (en) * 2013-03-12 2016-01-28 Biohit Oyj Encapsulated composition for binding aldehydes in the stomach
FI20135503L (fi) * 2013-05-13 2014-11-14 Biohit Oyj Kysteiini tai sen johdannainen atrofisen gastriitin hoitamiseen
FI20145217A (fi) * 2014-03-06 2015-09-07 Biohit Oyj Koostumus aldehydien ja vapaiden radikaalien sitomiseksi ruoansulatuskanavassa

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0012487D0 (en) * 2000-05-24 2000-07-12 Pfylori Limited Use of metal compounds to treat gastrointestinal infections
AU2003904192A0 (en) * 2003-08-11 2003-08-21 Adelaide Research and Innovaiton Pty Ltd Method for inhibiting bacterial colonisation
FI20060501L (fi) * 2006-05-22 2007-11-23 Biohit Oyj Koostumus ja menetelmä asetaldehydin sitomiseksi vatsassa
KR101188746B1 (ko) * 2009-09-23 2012-10-11 주식회사파마킹 에스-알릴-엘-시스테인을 유효성분으로 포함하는 위장질환 예방 또는 치료용 조성물

Also Published As

Publication number Publication date
WO2012143608A2 (en) 2012-10-26
WO2012143608A3 (en) 2012-12-13
CA2831650A1 (en) 2012-10-26
FI20115377A (fi) 2012-10-19
JP2014511896A (ja) 2014-05-19
FI20115377A0 (fi) 2011-04-18
US20140128336A1 (en) 2014-05-08
EP2699239A2 (en) 2014-02-26
CO6831981A2 (es) 2014-01-10

Similar Documents

Publication Publication Date Title
BR112013026909A2 (pt) Produtos medicinais para uso em condições correlacionadas a infecções microbianas no trato aerodigestivo superior
EA201170772A1 (ru) Органические соединения
NI201000110A (es) Derivados bicíclicos para usar en el tratamiento de afecciones asociadas con el receptor de andrógeno.
BR112015012670A2 (pt) composições de liberação controlada e métodos de uso
EA201001205A1 (ru) Соединения, содержащие циклобутоксигруппу
UY30759A1 (es) Compuestos quimicos
BR112012014190B8 (pt) composição farmacêutica para o tratamento da síndrome do olho seco
BRPI0922220B8 (pt) uso de compostos antibacterianos, composição farmacêutica e combinação compreendendo os mesmos
BR112013002484A2 (pt) composto, composição farmacêutica, métodos para tratar esclerose múltipla e artrite reumatoide, e, uso de um composto.
ECSP12011915A (es) Derivados de purina o deazapurina útiles para el tratamiento de inter alia infecciones virales.
UY32158A (es) Derivados heterociclicos y metodos de uso de los mismos
UY32174A (es) Nuevos heterociclos sustituidos, composiciones farmaceuticas conteniendolos, procedimientos de preparacion y aplicaciones
SV2010003737A (es) Derivados de indazol sustituidos con fenilo y benzodioxinilo
BR112013025260A2 (pt) óxido do tipo p, composição para produção de óxido do tipo p, método para produzir óxido do tipo p, dispositivo semicondutor, dispositivo de exibição, aparelho de exibição de imagem, e sistema
AR104174A1 (es) Oxadiazoles sustituidos con deuterio
BR112015011031A2 (pt) moduladores de grp40 de di-hidropirazol
ECSP099620A (es) Derivados de ciclohexano espirociclico
CL2010000804A1 (es) Compuestos derivados de 3-(1 h-pirrol-2-il-metil)-1 ,3-dihidro-2h-indol-2-ona; procedimientos de preparación de dichos compuestos; composición farmacéutica y combinación farmacéutica que los comprende; y su uso para el tratamiento de cáncer.
ECSP11011558A (es) Nuevos compuestos químicos.
BRPI0908539B8 (pt) processo para a preparação de uma forma sólida rápida de dosagem da dispersão, oral de alprazolam
GEP20166444B (en) Epoxyeicosatrienoic acid analogs and methods of making and using the same
UY32131A (es) Compuestos de anillo fusionado y uso de los mismos
BR112017008794A2 (pt) inibidores de di-heteroaril histona desacetilase e seu uso em terapia
BR112018010107A8 (pt) Composição farmacêutica para o tratamento ou prevenção de nash
EA201001855A1 (ru) Соединения, содержащие циклобутоксигруппу

Legal Events

Date Code Title Description
B15I Others concerning applications: loss of priority
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]