BR112013018845A2 - expressão de glicoproteínas de fusão viral solúveis em células de mamífero - Google Patents

expressão de glicoproteínas de fusão viral solúveis em células de mamífero

Info

Publication number
BR112013018845A2
BR112013018845A2 BR112013018845A BR112013018845A BR112013018845A2 BR 112013018845 A2 BR112013018845 A2 BR 112013018845A2 BR 112013018845 A BR112013018845 A BR 112013018845A BR 112013018845 A BR112013018845 A BR 112013018845A BR 112013018845 A2 BR112013018845 A2 BR 112013018845A2
Authority
BR
Brazil
Prior art keywords
expression
mammalian cell
viral fusion
fusion glycoproteins
cell soluble
Prior art date
Application number
BR112013018845A
Other languages
English (en)
Inventor
Gregory M Hayes
Hearther Lawlor
Peifeng Chen
Roderick Tang
Yi Liu
Original Assignee
Medimmune Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimmune Llc filed Critical Medimmune Llc
Publication of BR112013018845A2 publication Critical patent/BR112013018845A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18511Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18522New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00Nucleic acids vectors
    • C12N2800/22Vectors comprising a coding region that has been codon optimised for expression in a respective host
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/48Vector systems having a special element relevant for transcription regulating transport or export of RNA, e.g. RRE, PRE, WPRE, CTE

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BR112013018845A 2011-01-28 2012-01-27 expressão de glicoproteínas de fusão viral solúveis em células de mamífero BR112013018845A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161437531P 2011-01-28 2011-01-28
PCT/US2012/022997 WO2012103496A2 (en) 2011-01-28 2012-01-27 Expression of soluble viral fusion glycoproteins in mammalian cells

Publications (1)

Publication Number Publication Date
BR112013018845A2 true BR112013018845A2 (pt) 2016-07-19

Family

ID=46581434

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013018845A BR112013018845A2 (pt) 2011-01-28 2012-01-27 expressão de glicoproteínas de fusão viral solúveis em células de mamífero

Country Status (8)

Country Link
US (1) US20140024076A1 (pt)
EP (1) EP2668282A2 (pt)
JP (1) JP2014505477A (pt)
CN (1) CN103339140A (pt)
AU (1) AU2012211126A1 (pt)
BR (1) BR112013018845A2 (pt)
CA (1) CA2825722A1 (pt)
WO (1) WO2012103496A2 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2968518A4 (en) * 2013-03-15 2016-08-24 Vlp Biotech Inc VIRAL TYPE PARTICLES BASED ON PALIVIZUMAB EPITOPE
HUE059127T2 (hu) 2015-10-22 2022-10-28 Modernatx Inc Légúti vírusok elleni vakcinák
MA50335A (fr) 2016-12-08 2020-08-19 Modernatx Inc Vaccins à acide nucléique contre des virus respiratoires
CN106754677A (zh) * 2016-12-24 2017-05-31 严志海 一种体外骨髓间充质干细胞培养基
US20200030432A1 (en) 2017-03-17 2020-01-30 Modernatx, Inc. Zoonotic disease rna vaccines
WO2019066437A1 (ko) * 2017-09-29 2019-04-04 에스케이바이오사이언스 주식회사 가용성 변형 호흡기 융합세포 바이러스 (rsv) f 단백질 항원
US11351242B1 (en) 2019-02-12 2022-06-07 Modernatx, Inc. HMPV/hPIV3 mRNA vaccine composition
CN110894215B (zh) * 2019-12-16 2021-08-27 中国农业大学 一种小反刍兽疫病毒抗原以及检测小反刍兽疫病毒抗体的胶体金免疫层析试纸卡
TW202330922A (zh) * 2021-11-19 2023-08-01 美商Rna免疫公司 核糖核酸呼吸道融合病毒(rsv)疫苗之組合物及方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9200117D0 (en) * 1992-01-06 1992-02-26 Connaught Lab Production of recombinant chimeric proteins for vaccine use
WO2002042326A1 (en) * 2000-11-22 2002-05-30 Biota Scientific Management Pty Ltd A method of expression and agents identified thereby
DE102004037611B4 (de) * 2004-08-03 2013-10-02 Geneart Ag Induzierbare Genexpression
WO2008114149A2 (en) * 2007-03-21 2008-09-25 Id Biomedical Corporation Of Quebec Chimeric antigens
CN101293098A (zh) * 2007-04-28 2008-10-29 北京迪威华宇生物技术有限公司 一种重组牛o型口蹄疫病毒融合蛋白疫苗
CN104080475A (zh) * 2008-04-18 2014-10-01 法克斯因内特公司 鞭毛蛋白的缺失突变体以及使用方法
US20110181345A1 (en) * 2008-08-01 2011-07-28 President And Fellows Of Harvard College Phase transition devices and smart capacitive devices
WO2010149743A2 (en) * 2009-06-24 2010-12-29 Id Biomedical Corporation Of Quebec Vaccine

Also Published As

Publication number Publication date
CA2825722A1 (en) 2012-08-02
WO2012103496A2 (en) 2012-08-02
WO2012103496A3 (en) 2013-03-21
AU2012211126A1 (en) 2013-07-18
US20140024076A1 (en) 2014-01-23
JP2014505477A (ja) 2014-03-06
CN103339140A (zh) 2013-10-02
EP2668282A2 (en) 2013-12-04

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2395 DE 29-11-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.