BR112013002321A2 - processo para a preparação do composto osi-906 - Google Patents

processo para a preparação do composto osi-906

Info

Publication number
BR112013002321A2
BR112013002321A2 BR112013002321A BR112013002321A BR112013002321A2 BR 112013002321 A2 BR112013002321 A2 BR 112013002321A2 BR 112013002321 A BR112013002321 A BR 112013002321A BR 112013002321 A BR112013002321 A BR 112013002321A BR 112013002321 A2 BR112013002321 A2 BR 112013002321A2
Authority
BR
Brazil
Prior art keywords
preparation
compound
osi
compound osi
tyrosine kinase
Prior art date
Application number
BR112013002321A
Other languages
English (en)
Inventor
J Locke Andrew
J O'obrien Andrew
Michael Stevens Andrew
L Castelhano Arlindo
I Thomas Christopher
A Cutting Gary
A Rechka Josef
Michelle Mulvihill Kristen
Norrie Robert
R Park Stuart
Original Assignee
Osi Pharmaceuticals Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osi Pharmaceuticals Llc filed Critical Osi Pharmaceuticals Llc
Publication of BR112013002321A2 publication Critical patent/BR112013002321A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

processo para a preparação do composto osi-906. a presente invenção refere-se a um processo para a preparação do inibidor de tirosina quinase osi 906 que compreende acoplamento do composto (2) com o composto (6) em condições especificadas.
BR112013002321A 2010-07-30 2011-07-29 processo para a preparação do composto osi-906 BR112013002321A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36913210P 2010-07-30 2010-07-30
PCT/US2011/045807 WO2012016095A1 (en) 2010-07-30 2011-07-29 Process for the preparation of the compound osi - 906

Publications (1)

Publication Number Publication Date
BR112013002321A2 true BR112013002321A2 (pt) 2018-04-24

Family

ID=44528146

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013002321A BR112013002321A2 (pt) 2010-07-30 2011-07-29 processo para a preparação do composto osi-906

Country Status (9)

Country Link
US (1) US20130123501A1 (pt)
EP (1) EP2598506A1 (pt)
JP (1) JP2013537534A (pt)
CN (1) CN103025734A (pt)
BR (1) BR112013002321A2 (pt)
CA (1) CA2800345A1 (pt)
EA (1) EA201390183A1 (pt)
MX (1) MX2013001197A (pt)
WO (1) WO2012016095A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109182286B (zh) * 2018-09-21 2021-07-30 泰州学院 一种改进的氰基还原酶及其在合成3-氯吡嗪-2甲胺中的应用
KR102159121B1 (ko) 2019-01-25 2020-09-23 엘티소재주식회사 화합물, 유기 광전자 소자 및 표시 장치
CN113143928A (zh) * 2021-04-02 2021-07-23 苏州普乐康医药科技有限公司 一种osi-906的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1740591E (pt) 2004-04-02 2009-09-24 Osi Pharm Inc Inibidores da proteína quinase heterobicíclicos em substituição de anel bicíclico 6,6
TW200730529A (en) 2005-12-07 2007-08-16 Osi Pharm Inc Process to prepare substituted imidazopyrazine compounds

Also Published As

Publication number Publication date
CA2800345A1 (en) 2012-02-02
JP2013537534A (ja) 2013-10-03
WO2012016095A8 (en) 2013-11-21
EA201390183A1 (ru) 2013-05-30
CN103025734A (zh) 2013-04-03
WO2012016095A1 (en) 2012-02-02
MX2013001197A (es) 2013-06-03
EP2598506A1 (en) 2013-06-05
US20130123501A1 (en) 2013-05-16

Similar Documents

Publication Publication Date Title
CR20120011A (es) Inhibidores de bace
CL2016001732A1 (es) Métodos sintéticos para compuestos espiro-oxoindol (div. sol. 3633-13).
BR112012007085B8 (pt) processos para a preparação de derivados de benzil-benzeno substituídos com glicopiranosila
CR20140232A (es) Agentes de iarn, composiciones y métodos de uso de los mismos para tratar enfermedades asociadas con transtiretina (ttr)
BRPI0816911A8 (pt) Processo para preparação de 4-aminobut-2-enolidas
DOP2010000328A (es) Inhibidores de bace
CR20110467A (es) Derivados de benzofuranilo como inhibidores de la glucoquinasa
BR112014009292A2 (pt) processo de formação de fibras e fibras produzidas pelo processo
BRPI0911254A2 (pt) processo para a preparação de um composto
CR20130233A (es) Derivados que quinazolin-4 (3h)-ona utilizados como inhibidores de pi3 cinaza
BRPI1011516A8 (pt) Aglomerado de pelo menos uma partícula p, processo para a produção de aglomerados, e, uso dos aglomerados.
CL2009000503A1 (es) Proceso de preparacion de compuestos derivados de acido 2-amino-5-cianobenzoico-3-sustituidos o 1h-pirazol-5-carboxamida.
BR112014018756A8 (pt) Processo para preparo de etil éster de ácido n-(4-ciclo-hexil-3-trifluorometil-benziloxi)-acetimídico
BR112012029925A2 (pt) pedra-pomes granulada, bem como processo para produção de pedra-pomes granulada
BR112015020716A2 (pt) processo para a preparação de (2-(4-(2-(1-isopropil-3-metil-1h-1,2,4-triazol-5-il)-5,6-diidrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-il)-1h-pirazol-1-il)-2-metilpropanamida (i) e composto
BRPI0817747A8 (pt) Processo para a preparação de derivados de ácido 2-di-halogenoacil-3-amino-acrílico
BR122018074319B8 (pt) Método para preparar um composto de fórmula 14
MX371356B (es) Profarmacos de aminoquinazolina inhibidora de cinasa.
BR112015032393A2 (pt) processo para a preparação estereosseletiva de uma pirazol-carboxamida
BR112014010061A2 (pt) processo para a preparação de n-alquil(met)acrila-midas
BR112015024859A2 (pt) processo e intermediários para a preparação de pregabalina
UY31704A (es) Compuesto heterociclico fusionado
BRPI1010571A2 (pt) processo para a preparação de um composto útil como um inibidor de tafla.
UY32075A (es) Estabilización de preparaciones acuosas de minerales mediante reuterina
BR112013002321A2 (pt) processo para a preparação do composto osi-906

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B15I Others concerning applications: loss of priority
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired
B350 Update of information on the portal [chapter 15.35 patent gazette]