BR112012016799A2 - tratamento da síndrome de apneia obstrutiva do sono com uma combinação de um inibidor da anidrase carbônica e um agente ativo adicional - Google Patents
tratamento da síndrome de apneia obstrutiva do sono com uma combinação de um inibidor da anidrase carbônica e um agente ativo adicional Download PDFInfo
- Publication number
- BR112012016799A2 BR112012016799A2 BR112012016799A BR112012016799A BR112012016799A2 BR 112012016799 A2 BR112012016799 A2 BR 112012016799A2 BR 112012016799 A BR112012016799 A BR 112012016799A BR 112012016799 A BR112012016799 A BR 112012016799A BR 112012016799 A2 BR112012016799 A2 BR 112012016799A2
- Authority
- BR
- Brazil
- Prior art keywords
- modafinil
- carbonic anhydrase
- effective amount
- therapeutically effective
- anhydrase inhibitor
- Prior art date
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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Landscapes
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| PCT/US2011/020588 WO2011085256A2 (en) | 2010-01-07 | 2011-01-07 | Treatment of obstructive sleep apnea syndrome with a combination of a carbonic anhydrase inhibitor and an additional active agent |
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| US7674776B2 (en) | 1999-06-14 | 2010-03-09 | Vivus, Inc. | Combination therapy for effecting weight loss and treating obesity |
| US8580298B2 (en) | 2008-06-09 | 2013-11-12 | Vivus, Inc. | Low dose topiramate/phentermine composition and methods of use thereof |
| US20090304789A1 (en) | 2008-06-09 | 2009-12-10 | Thomas Najarian | Novel topiramate compositions and an escalating dosing strategy for treating obesity and related disorders |
| US8652527B1 (en) | 2013-03-13 | 2014-02-18 | Upsher-Smith Laboratories, Inc | Extended-release topiramate capsules |
| US9101545B2 (en) | 2013-03-15 | 2015-08-11 | Upsher-Smith Laboratories, Inc. | Extended-release topiramate capsules |
| US20160045527A1 (en) * | 2014-08-14 | 2016-02-18 | Vivus, Inc. | Treatment of sleep apnea with a combination of a carbonic anhydrase inhibitor and an aldosterone antagonist |
| US20160367503A1 (en) * | 2015-06-20 | 2016-12-22 | Cary Erwin Fechter | Combination Medication for Neuro-Degenerative Diseases |
| WO2017007577A1 (en) | 2015-07-08 | 2017-01-12 | Gilrose Pharmaceuticals, Llc | Pre-frontal cortex processing disorder, gait and limb impairment treatment |
| DK3423062T3 (da) | 2016-05-11 | 2020-08-31 | Jan Hedner | Sultiam til behandlingen af søvnapnø |
| EP3846794A4 (en) * | 2018-09-06 | 2022-06-22 | Monash University | METHODS OF TREATMENT OF A SLEEP BREATHING DISORDER |
| US20220362221A1 (en) * | 2019-11-04 | 2022-11-17 | Apnimed, Inc. (Delaware) | Combination pharmacological interventions for multiple mechanisms of obstructive sleep apnea |
| US12046341B2 (en) | 2021-10-05 | 2024-07-23 | Bradford Rabin | Methods and systems for electronically adjusting a dosing pattern of a patient undergoing a medical regimen |
| WO2025191322A1 (en) * | 2024-03-11 | 2025-09-18 | Mousavi Mirzaei Seyed Mohammad | Therapeutic composition for improving symptoms of obstructive sleep apnea |
| WO2025207125A1 (en) * | 2024-03-26 | 2025-10-02 | The Regents Of The University Of California | Combination pharmacological interventions for obstructive sleep apnea |
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| US20080255093A1 (en) * | 1999-06-14 | 2008-10-16 | Tam Peter Y | Compositions and methods for treating obesity and related disorders |
| US7553818B2 (en) * | 1999-06-14 | 2009-06-30 | Vivus, Inc. | Combination therapy for effecting weight loss and treating obesity |
| US7056890B2 (en) * | 1999-06-14 | 2006-06-06 | Vivus, Inc. | Combination therapy for effecting weight loss and treating obesity |
| SE0000601D0 (sv) * | 2000-02-24 | 2000-02-24 | Jan Hedner | Sätt att behandla och diagnostisera andningsstörningar i sömnen och medel för att utföra sättet |
| FR2849029B1 (fr) * | 2002-12-20 | 2005-03-18 | Lafon Labor | Procede de preparation et formes cristallines des enantiomeres optiques du modafinil. |
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| EP1516869A1 (en) * | 2003-09-19 | 2005-03-23 | Cephalon France | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation |
| JP5646126B2 (ja) * | 2003-12-11 | 2014-12-24 | サノビオン ファーマシューティカルズ インクＳｕｎｏｖｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． | 鎮静剤と神経伝達物質調節剤の併用、および睡眠の質の向上方法および鬱の治療方法 |
| WO2005063248A1 (en) * | 2003-12-22 | 2005-07-14 | Sepracor Inc. | Modafinil combination therapy for improving sleep quality |
| SE0400378D0 (sv) * | 2004-02-17 | 2004-02-17 | Jan Hedner | Sätt att behandla och diagnostisera andningsstörningar i sömnen och medel för att utföra sättet |
| WO2006023702A2 (en) * | 2004-08-20 | 2006-03-02 | Cypress Bioscience, Inc. | Method for treating sleep related breathing disorders with setiptiline |
| CN101132777A (zh) * | 2004-12-20 | 2008-02-27 | 科利吉姆制药公司 | 用于睡眠障碍的药物组合物 |
| KR20080059208A (ko) * | 2005-09-16 | 2008-06-26 | 세레우사이언스 아베 | 수면 호흡 장애를 예방 및 치료하는 방법과 그 수단 |
| CA2673481A1 (en) * | 2006-12-19 | 2008-06-26 | University Of Virginia Patent Foundation | Combined effects of topiramate and ondansetron on alcohol consumption |
| WO2008095086A2 (en) * | 2007-01-31 | 2008-08-07 | University Of Virginia Patent Foundation | Topiramate plus naltrexone for the treatment of addictive disorders |
| EP2142183A2 (en) * | 2007-04-09 | 2010-01-13 | Sepracor Inc. | Methods and compositions comprising desvenlafaxine or duloxetine for treating sleep-related breathing disorders |
| EP2155664A2 (en) * | 2007-06-04 | 2010-02-24 | Generics Ýuk¨Limited | Novel process |
| US8071557B2 (en) * | 2007-06-13 | 2011-12-06 | Vivus, Inc. | Treatment of pulmonary hypertension with carbonic anhydrase inhibitors |
| US20090304789A1 (en) * | 2008-06-09 | 2009-12-10 | Thomas Najarian | Novel topiramate compositions and an escalating dosing strategy for treating obesity and related disorders |
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| AU2011203970A1 (en) | 2012-07-12 |
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| CA2786026A1 (en) | 2011-07-14 |
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| KR20120101588A (ko) | 2012-09-13 |
| IN2012DN06616A (enExample) | 2015-10-23 |
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