BR112012011224A2 - teobromina e agente combinado com um opióide antitussígeno e seu uso terapêutico - Google Patents
teobromina e agente combinado com um opióide antitussígeno e seu uso terapêuticoInfo
- Publication number
- BR112012011224A2 BR112012011224A2 BR112012011224A BR112012011224A BR112012011224A2 BR 112012011224 A2 BR112012011224 A2 BR 112012011224A2 BR 112012011224 A BR112012011224 A BR 112012011224A BR 112012011224 A BR112012011224 A BR 112012011224A BR 112012011224 A2 BR112012011224 A2 BR 112012011224A2
- Authority
- BR
- Brazil
- Prior art keywords
- theobromine
- opioid
- antitussive
- therapeutic use
- agent combined
- Prior art date
Links
- YAPQBXQYLJRXSA-UHFFFAOYSA-N theobromine Chemical compound CN1C(=O)NC(=O)C2=C1N=CN2C YAPQBXQYLJRXSA-UHFFFAOYSA-N 0.000 title abstract 6
- 229960004559 theobromine Drugs 0.000 title abstract 3
- 230000000954 anitussive effect Effects 0.000 title abstract 2
- 229940124584 antitussives Drugs 0.000 title abstract 2
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical compound C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 238000002560 therapeutic procedure Methods 0.000 abstract 2
- 206010011224 Cough Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0919893.8A GB0919893D0 (en) | 2009-11-13 | 2009-11-13 | Drug composition and its use in therapy |
| PCT/GB2010/051896 WO2011058374A1 (en) | 2009-11-13 | 2010-11-12 | Drug combination with theobromine and its use in therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112012011224A2 true BR112012011224A2 (pt) | 2017-03-01 |
Family
ID=41509327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112012011224A BR112012011224A2 (pt) | 2009-11-13 | 2010-11-12 | teobromina e agente combinado com um opióide antitussígeno e seu uso terapêutico |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP2498776A1 (https=) |
| JP (2) | JP2013510842A (https=) |
| CN (1) | CN102740853B (https=) |
| AU (1) | AU2010317668C1 (https=) |
| BR (1) | BR112012011224A2 (https=) |
| CA (1) | CA2780704C (https=) |
| CO (1) | CO6551745A2 (https=) |
| EC (2) | ECSP12011893A (https=) |
| GB (1) | GB0919893D0 (https=) |
| IL (1) | IL219769A0 (https=) |
| MX (1) | MX2012005538A (https=) |
| NZ (1) | NZ599957A (https=) |
| PE (1) | PE20121472A1 (https=) |
| PH (1) | PH12012500955A1 (https=) |
| RU (1) | RU2587329C2 (https=) |
| SG (1) | SG10201407496SA (https=) |
| UA (1) | UA105940C2 (https=) |
| WO (1) | WO2011058374A1 (https=) |
| ZA (1) | ZA201204247B (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201111485D0 (en) * | 2011-07-05 | 2011-08-17 | Biocopea Ltd | Drug composition and its use in therapy |
| US10016437B2 (en) | 2009-06-16 | 2018-07-10 | Infirst Healthcare Limited | Drug combinations and uses in treating a coughing condition |
| US9314465B2 (en) | 2009-06-16 | 2016-04-19 | Infirst Healthcare Limited | Drug combinations and uses in treating a coughing condition |
| GB0910375D0 (en) | 2009-06-16 | 2009-07-29 | Biocopea Ltd | Drug composition and its use in therapy |
| US9308211B2 (en) | 2009-06-16 | 2016-04-12 | Infirst Healthcare Limited | Drug combinations and uses in treating a coughing condition |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0339054B1 (de) * | 1987-10-08 | 1994-07-06 | Andor Bilas | Stoffgemisch zur stabilisierung der stoffwechsel-lage |
| WO1995007103A1 (en) * | 1993-09-07 | 1995-03-16 | The Procter & Gamble Company | Compositions containing an amino acid salt of propionic acid non-steroidal anti-inflammatory agent and at least one of a decongestant, an expectorant, an antihistamine and an antitussive |
| HUP9700654A2 (hu) * | 1997-03-26 | 1999-09-28 | Dezső Korbonits | Teobromin tartalmú köhögéscsillapító készítmények |
| US6608073B1 (en) * | 1998-10-14 | 2003-08-19 | New Millennium Pharmaceutical Research, Inc. | Intranasal codeine for the rapid suppression of cough and rapid relief of pain |
| HUP9802716A3 (en) * | 1998-11-25 | 2000-08-28 | Chinoin Gyogyszer Es Vegyeszet | Pharmaceutical composition of analgesic activity |
| EP1465634B1 (en) * | 2001-12-12 | 2014-10-22 | The Government of the United States of America, as represented by the Secretary Department of Health and Human Services | Methods for using adenosine receptor inhibitors to enhance immune response and inflammation |
| AU2004216550B2 (en) * | 2003-02-28 | 2010-06-03 | Ym Biosciences Inc. | Opioid delivery system |
| CN1593451A (zh) * | 2003-09-12 | 2005-03-16 | 杨喜鸿 | 促进男性勃起的外用药物 |
| CA2594987A1 (en) * | 2004-12-14 | 2006-06-22 | Shionogi & Co., Ltd. | Therapeutic agent for constipation |
| US20080003280A1 (en) * | 2006-06-26 | 2008-01-03 | Levine Brian M | Combination cough treatment compounds and method of treating common coughs |
| KR20080009994A (ko) * | 2006-07-25 | 2008-01-30 | 안국약품 주식회사 | 기침 치료용 조성물 |
-
2009
- 2009-11-13 GB GBGB0919893.8A patent/GB0919893D0/en not_active Ceased
-
2010
- 2010-11-12 BR BR112012011224A patent/BR112012011224A2/pt not_active IP Right Cessation
- 2010-11-12 JP JP2012538416A patent/JP2013510842A/ja active Pending
- 2010-11-12 CA CA2780704A patent/CA2780704C/en not_active Expired - Fee Related
- 2010-11-12 PE PE2012000650A patent/PE20121472A1/es not_active Application Discontinuation
- 2010-11-12 UA UAA201207163A patent/UA105940C2/uk unknown
- 2010-11-12 NZ NZ599957A patent/NZ599957A/en not_active IP Right Cessation
- 2010-11-12 MX MX2012005538A patent/MX2012005538A/es unknown
- 2010-11-12 WO PCT/GB2010/051896 patent/WO2011058374A1/en not_active Ceased
- 2010-11-12 EP EP10778715A patent/EP2498776A1/en not_active Ceased
- 2010-11-12 CN CN201080051628.4A patent/CN102740853B/zh not_active Expired - Fee Related
- 2010-11-12 AU AU2010317668A patent/AU2010317668C1/en not_active Ceased
- 2010-11-12 SG SG10201407496SA patent/SG10201407496SA/en unknown
- 2010-11-12 PH PH1/2012/500955A patent/PH12012500955A1/en unknown
- 2010-11-12 RU RU2012124063/15A patent/RU2587329C2/ru not_active IP Right Cessation
-
2012
- 2012-05-11 CO CO12078022A patent/CO6551745A2/es not_active Application Discontinuation
- 2012-05-11 EC ECSP12011893 patent/ECSP12011893A/es unknown
- 2012-05-11 EC ECSP12011892 patent/ECSP12011892A/es unknown
- 2012-05-13 IL IL219769A patent/IL219769A0/en unknown
- 2012-06-11 ZA ZA2012/04247A patent/ZA201204247B/en unknown
-
2015
- 2015-12-04 JP JP2015237086A patent/JP2016041748A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2013510842A (ja) | 2013-03-28 |
| RU2012124063A (ru) | 2013-12-20 |
| SG10201407496SA (en) | 2015-02-27 |
| AU2010317668B2 (en) | 2015-01-22 |
| UA105940C2 (uk) | 2014-07-10 |
| GB0919893D0 (en) | 2009-12-30 |
| IL219769A0 (en) | 2012-07-31 |
| AU2010317668C1 (en) | 2016-02-11 |
| ZA201204247B (en) | 2013-02-27 |
| PE20121472A1 (es) | 2012-11-30 |
| AU2010317668A1 (en) | 2012-06-07 |
| CA2780704A1 (en) | 2011-05-19 |
| ECSP12011892A (es) | 2012-09-28 |
| EP2498776A1 (en) | 2012-09-19 |
| CN102740853B (zh) | 2015-04-08 |
| PH12012500955A1 (en) | 2013-01-07 |
| RU2587329C2 (ru) | 2016-06-20 |
| ECSP12011893A (es) | 2012-10-30 |
| WO2011058374A1 (en) | 2011-05-19 |
| JP2016041748A (ja) | 2016-03-31 |
| NZ599957A (en) | 2014-05-30 |
| CA2780704C (en) | 2018-07-17 |
| CN102740853A (zh) | 2012-10-17 |
| MX2012005538A (es) | 2012-09-28 |
| CO6551745A2 (es) | 2012-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO ARQUIVAMENTO PUBLICADO NA RPI 2493 DE 16/10/2018. |