BR112012011224A2 - theobromine and agent combined with an antitussive opioid and its therapeutic use - Google Patents

theobromine and agent combined with an antitussive opioid and its therapeutic use

Info

Publication number
BR112012011224A2
BR112012011224A2 BR112012011224A BR112012011224A BR112012011224A2 BR 112012011224 A2 BR112012011224 A2 BR 112012011224A2 BR 112012011224 A BR112012011224 A BR 112012011224A BR 112012011224 A BR112012011224 A BR 112012011224A BR 112012011224 A2 BR112012011224 A2 BR 112012011224A2
Authority
BR
Brazil
Prior art keywords
theobromine
opioid
antitussive
therapeutic use
agent combined
Prior art date
Application number
BR112012011224A
Other languages
Portuguese (pt)
Inventor
Robin Mark Bannister
John Brew
Original Assignee
Biocopea Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocopea Ltd filed Critical Biocopea Ltd
Publication of BR112012011224A2 publication Critical patent/BR112012011224A2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • A61K31/522Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

teobromina e agente combinado com um opióide antitussígeno e seu uso terapêutico. um agente que compreende teobromina e um opióide antisussígeno, para um simultâneo, sequencial ou separado, em terapias. preferivelmente em terapias da tosse.theobromine and agent combined with an antitussive opioid and its therapeutic use. an agent comprising theobromine and an antisussive opioid for simultaneous, sequential or separate in therapies. preferably in cough therapies.

BR112012011224A 2009-11-13 2010-11-12 theobromine and agent combined with an antitussive opioid and its therapeutic use BR112012011224A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0919893.8A GB0919893D0 (en) 2009-11-13 2009-11-13 Drug composition and its use in therapy
PCT/GB2010/051896 WO2011058374A1 (en) 2009-11-13 2010-11-12 Drug combination with theobromine and its use in therapy

Publications (1)

Publication Number Publication Date
BR112012011224A2 true BR112012011224A2 (en) 2017-03-01

Family

ID=41509327

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012011224A BR112012011224A2 (en) 2009-11-13 2010-11-12 theobromine and agent combined with an antitussive opioid and its therapeutic use

Country Status (18)

Country Link
EP (1) EP2498776A1 (en)
JP (2) JP2013510842A (en)
CN (1) CN102740853B (en)
AU (1) AU2010317668C1 (en)
BR (1) BR112012011224A2 (en)
CA (1) CA2780704C (en)
CO (1) CO6551745A2 (en)
EC (2) ECSP12011893A (en)
GB (1) GB0919893D0 (en)
IL (1) IL219769A0 (en)
MX (1) MX2012005538A (en)
NZ (1) NZ599957A (en)
PE (1) PE20121472A1 (en)
RU (1) RU2587329C2 (en)
SG (1) SG10201407496SA (en)
UA (1) UA105940C2 (en)
WO (1) WO2011058374A1 (en)
ZA (1) ZA201204247B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9308211B2 (en) 2009-06-16 2016-04-12 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
GB0910375D0 (en) 2009-06-16 2009-07-29 Biocopea Ltd Drug composition and its use in therapy
US9314465B2 (en) 2009-06-16 2016-04-19 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
US10016437B2 (en) 2009-06-16 2018-07-10 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
GB201111485D0 (en) * 2011-07-05 2011-08-17 Biocopea Ltd Drug composition and its use in therapy

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3850568D1 (en) * 1987-10-08 1994-08-11 Andor Bilas FABRIC MIXTURE TO STABILIZE THE METABOLISM LOCATION.
BR9407414A (en) * 1993-09-07 1996-11-12 Procter & Gamble Compositions containing a non-steroidal propionic acid anti-inflammatory agent amino acid salt and at least one decongestant an expectorant an antihistamine and an antitussive
HUP9700654A2 (en) 1997-03-26 1999-09-28 Dezső Korbonits Antitussive compositions containing theobromine
US6608073B1 (en) * 1998-10-14 2003-08-19 New Millennium Pharmaceutical Research, Inc. Intranasal codeine for the rapid suppression of cough and rapid relief of pain
HUP9802716A3 (en) * 1998-11-25 2000-08-28 Chinoin Gyogyszer Es Vegyeszet Pharmaceutical composition of analgesic activity
US8080554B2 (en) * 2001-12-12 2011-12-20 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Methods for using extracellular adenosine inhibitors and adenosine receptor inhibitors to enhance immune response and inflammation
EP1603533B1 (en) * 2003-02-28 2009-04-15 YM Biosciences Inc. Opioid delivery system
CN1593451A (en) * 2003-09-12 2005-03-16 杨喜鸿 Externally applied medicine for promoting male erection
EP1844792A4 (en) * 2004-12-14 2008-05-21 Shionogi & Co Therapeutic agent for constipation
US20080003280A1 (en) * 2006-06-26 2008-01-03 Levine Brian M Combination cough treatment compounds and method of treating common coughs
KR20080009994A (en) * 2006-07-25 2008-01-30 안국약품 주식회사 Compositions for treating of cough

Also Published As

Publication number Publication date
GB0919893D0 (en) 2009-12-30
JP2013510842A (en) 2013-03-28
WO2011058374A1 (en) 2011-05-19
RU2587329C2 (en) 2016-06-20
UA105940C2 (en) 2014-07-10
JP2016041748A (en) 2016-03-31
EP2498776A1 (en) 2012-09-19
AU2010317668A1 (en) 2012-06-07
AU2010317668B2 (en) 2015-01-22
AU2010317668C1 (en) 2016-02-11
SG10201407496SA (en) 2015-02-27
ECSP12011893A (en) 2012-10-30
CA2780704C (en) 2018-07-17
ECSP12011892A (en) 2012-09-28
CA2780704A1 (en) 2011-05-19
NZ599957A (en) 2014-05-30
RU2012124063A (en) 2013-12-20
IL219769A0 (en) 2012-07-31
PE20121472A1 (en) 2012-11-30
ZA201204247B (en) 2013-02-27
CO6551745A2 (en) 2012-10-31
CN102740853B (en) 2015-04-08
CN102740853A (en) 2012-10-17
MX2012005538A (en) 2012-09-28

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO ARQUIVAMENTO PUBLICADO NA RPI 2493 DE 16/10/2018.