BR112012001159A2 - benzenossulfonato de 2 - [[[2 -[(hidroxiacetil) amino]- 4 -piridinil] metil] tio]- n -[4 - (trifluorometóxi) fenil]- 3 - piridinacarboxamida, cristal do mesmo, cristal polimorfo do mesmo, e métodos para produção do mesmo - Google Patents
benzenossulfonato de 2 - [[[2 -[(hidroxiacetil) amino]- 4 -piridinil] metil] tio]- n -[4 - (trifluorometóxi) fenil]- 3 - piridinacarboxamida, cristal do mesmo, cristal polimorfo do mesmo, e métodos para produção do mesmoInfo
- Publication number
- BR112012001159A2 BR112012001159A2 BR112012001159A BR112012001159A BR112012001159A2 BR 112012001159 A2 BR112012001159 A2 BR 112012001159A2 BR 112012001159 A BR112012001159 A BR 112012001159A BR 112012001159 A BR112012001159 A BR 112012001159A BR 112012001159 A2 BR112012001159 A2 BR 112012001159A2
- Authority
- BR
- Brazil
- Prior art keywords
- hydroxyacetyl
- trifluoromethoxy
- pyridinyl
- thio
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/32—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of salts of sulfonic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/29—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton of non-condensed six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009169130 | 2009-07-17 | ||
| PCT/JP2010/062071 WO2011007870A1 (ja) | 2009-07-17 | 2010-07-16 | ２－［［［２－［（ヒドロキシアセチル）アミノ］－４－ピリジニル］メチル］チオ］－ｎ－［４－（トリフルオロメトキシ）フェニル］－３－ピリジンカルボキサミドのベンゼンスルホン酸塩、その結晶、その結晶多形およびそれらの製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112012001159A2 true BR112012001159A2 (pt) | 2016-03-01 |
Family
ID=43449480
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112012001159A BR112012001159A2 (pt) | 2009-07-17 | 2010-07-16 | benzenossulfonato de 2 - [[[2 -[(hidroxiacetil) amino]- 4 -piridinil] metil] tio]- n -[4 - (trifluorometóxi) fenil]- 3 - piridinacarboxamida, cristal do mesmo, cristal polimorfo do mesmo, e métodos para produção do mesmo |
Country Status (17)
| Country | Link |
|---|---|
| US (4) | US9029398B2 (pt) |
| EP (1) | EP2455368B1 (pt) |
| JP (1) | JP5662719B2 (pt) |
| KR (1) | KR101710740B1 (pt) |
| CN (1) | CN102471273B (pt) |
| AU (1) | AU2010271746B2 (pt) |
| BR (1) | BR112012001159A2 (pt) |
| CA (1) | CA2767992C (pt) |
| EA (1) | EA019689B1 (pt) |
| ES (1) | ES2554360T3 (pt) |
| HK (2) | HK1167644A1 (pt) |
| IN (1) | IN2012DN01152A (pt) |
| MX (1) | MX2012000749A (pt) |
| MY (1) | MY157122A (pt) |
| NZ (1) | NZ597495A (pt) |
| SG (1) | SG177576A1 (pt) |
| WO (1) | WO2011007870A1 (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201606271RA (en) | 2012-01-31 | 2016-09-29 | Santen Pharmaceutical Co Ltd | Non-aqueous liquid composition |
| JP5856264B2 (ja) * | 2013-09-20 | 2016-02-09 | 参天製薬株式会社 | ポリエチレングリコール含有組成物 |
| TW201609145A (zh) | 2013-12-25 | 2016-03-16 | 參天製藥股份有限公司 | 注射劑及形成緩釋（ｄｅｐｏｔ）之方法 |
| EP3272360B1 (en) * | 2015-03-17 | 2022-11-23 | Santen Pharmaceutical Co., Ltd. | Pharmaceutical composition comprising polypeptide |
| KR20230104762A (ko) * | 2015-03-18 | 2023-07-10 | 산텐 세이야꾸 가부시키가이샤 | 서방성 의약 조성물 |
| TW201639568A (zh) * | 2015-03-18 | 2016-11-16 | 參天製藥股份有限公司 | 醫藥組成物之安定保存 |
| WO2016178900A1 (en) * | 2015-05-01 | 2016-11-10 | Odin Biotech | Ocular implant for delivery of pyridinecarboxamide derivative |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4626353B2 (ja) * | 2004-02-17 | 2011-02-09 | 参天製薬株式会社 | 置換又は無置換アミノ基を導入した４−ピリジルアルキルチオ基を有する新規環式化合物 |
| ATE512950T1 (de) | 2004-02-17 | 2011-07-15 | Santen Pharmaceutical Co Ltd | Neue cyclische verbindung mit 4- pyridylalkylthiogruppe mit darin eingeführtem (un)substituiertem amino |
| CN1918127B (zh) * | 2004-02-17 | 2012-02-15 | 参天制药株式会社 | 具有引入了取代或无取代氨基的4-吡啶基烷硫基的环状化合物 |
| EP1864977B1 (en) * | 2005-03-31 | 2015-07-29 | Santen Pharmaceutical Co., Ltd. | Novel cyclic compound having pyrimidinylalkylthio group |
| JP4834441B2 (ja) | 2005-03-31 | 2011-12-14 | 参天製薬株式会社 | ピリミジニルアルキルチオ基を有する新規環式化合物 |
-
2010
- 2010-07-16 EA EA201200146A patent/EA019689B1/ru not_active IP Right Cessation
- 2010-07-16 EP EP10799928.6A patent/EP2455368B1/en not_active Not-in-force
- 2010-07-16 AU AU2010271746A patent/AU2010271746B2/en not_active Ceased
- 2010-07-16 MX MX2012000749A patent/MX2012000749A/es active IP Right Grant
- 2010-07-16 CA CA2767992A patent/CA2767992C/en not_active Expired - Fee Related
- 2010-07-16 KR KR1020127003670A patent/KR101710740B1/ko active IP Right Grant
- 2010-07-16 WO PCT/JP2010/062071 patent/WO2011007870A1/ja active Application Filing
- 2010-07-16 US US13/384,590 patent/US9029398B2/en not_active Expired - Fee Related
- 2010-07-16 SG SG2012001467A patent/SG177576A1/en unknown
- 2010-07-16 NZ NZ597495A patent/NZ597495A/xx not_active IP Right Cessation
- 2010-07-16 BR BR112012001159A patent/BR112012001159A2/pt not_active IP Right Cessation
- 2010-07-16 MY MYPI2011006369A patent/MY157122A/en unknown
- 2010-07-16 CN CN201080031652.1A patent/CN102471273B/zh not_active Expired - Fee Related
- 2010-07-16 IN IN1152DEN2012 patent/IN2012DN01152A/en unknown
- 2010-07-16 JP JP2010161881A patent/JP5662719B2/ja not_active Expired - Fee Related
- 2010-07-16 ES ES10799928.6T patent/ES2554360T3/es active Active
-
2012
- 2012-08-23 HK HK12108284.4A patent/HK1167644A1/xx not_active IP Right Cessation
- 2012-08-28 HK HK12108386.1A patent/HK1167647A1/xx not_active IP Right Cessation
-
2015
- 2015-04-14 US US14/686,577 patent/US9359328B2/en not_active Expired - Fee Related
-
2016
- 2016-05-10 US US15/150,901 patent/US9546140B2/en not_active Expired - Fee Related
- 2016-12-02 US US15/368,028 patent/US9902698B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US9546140B2 (en) | 2017-01-17 |
| EP2455368B1 (en) | 2015-09-16 |
| KR101710740B1 (ko) | 2017-02-27 |
| US20160251314A1 (en) | 2016-09-01 |
| EP2455368A1 (en) | 2012-05-23 |
| MX2012000749A (es) | 2012-01-27 |
| US20170081286A1 (en) | 2017-03-23 |
| US9359328B2 (en) | 2016-06-07 |
| JP2011037844A (ja) | 2011-02-24 |
| US9029398B2 (en) | 2015-05-12 |
| US20150291560A1 (en) | 2015-10-15 |
| CA2767992C (en) | 2017-03-21 |
| HK1167647A1 (en) | 2012-12-07 |
| NZ597495A (en) | 2013-08-30 |
| IN2012DN01152A (en) | 2015-04-10 |
| CN102471273B (zh) | 2014-07-16 |
| CN102471273A (zh) | 2012-05-23 |
| EA019689B1 (ru) | 2014-05-30 |
| KR20130025857A (ko) | 2013-03-12 |
| EP2455368A4 (en) | 2013-01-09 |
| JP5662719B2 (ja) | 2015-02-04 |
| EA201200146A1 (ru) | 2012-06-29 |
| US20120116088A1 (en) | 2012-05-10 |
| CA2767992A1 (en) | 2011-01-20 |
| AU2010271746B2 (en) | 2014-07-03 |
| US9902698B2 (en) | 2018-02-27 |
| MY157122A (en) | 2016-05-13 |
| WO2011007870A1 (ja) | 2011-01-20 |
| SG177576A1 (en) | 2012-02-28 |
| AU2010271746A1 (en) | 2012-02-02 |
| ES2554360T3 (es) | 2015-12-18 |
| HK1167644A1 (en) | 2012-12-07 |
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| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2523 DE 14-05-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |
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