BR102016023137A2 - NON-MINERAL OR SYNTHETIC EXTRACREDITED OIL, ITS USE, PERSONAL CARE COMPOSITION, COSMETIC, FOOD COMPOSITION, PHARMACEUTICAL COMPOSITION, ANIMAL CARE COMPOSITION AND DENTAL INDIRECT CARE COMPOSITION - Google Patents

Abstract

The present invention relates to an extrarrefined oil of non-mineral or synthetic origin with high antioxidant stability capable of being a substitute for the widely used mineral or synthetic oil while providing greater stability compared to the present invention. food grade refined vegetable oil. In particular, the present invention is directed to the application of extra-refined vegetable oil in personal, cosmetic, food, pharmaceutical, animal care or home care compositions.

Description

(54) Title: EXTRARRINATED OIL OF NON-MINERAL OR SYNTHETIC ORIGIN, ITS USE, COMPOSITION FOR PERSONAL CARE, COSMETICS, FOOD COMPOSITION, COMPOSITION

PHARMACEUTICAL, COMPOSITION FOR ANIMAL CARE AND COMPOSITIONS FOR HOME CARE UNDERSTANDING THAT OIL AND PRODUCT UNDERSTANDING EXTRARRINATED OIL OF NON-MINERAL OR SYNTHETIC ORIGIN (51) Int. Cl .: C11B 1/10 (73) Holder (s): CARGILL, INCORPOR (72) Inventor (s): CINTIA BARADEL; HELIO HARUO USHIJIMA (74) Attorney (s): DANNEMANN, SIEMSEN, BIGLER & IPANEMA MOREIRA (57) Abstract: The present invention relates to an extrarrefined oil of non-mineral or synthetic origin, with high antioxidative stability, capable of being a substitute for mineral or synthetic oil, currently used on a large scale, while providing greater stability compared to refined vegetable oil of food standard (food grade). The present invention aims, in particular, the application of extra-refined vegetable oil in personal care, cosmetic, food, pharmaceutical, animal or home care compositions.

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Invention Patent Descriptive Report for EXTRARREFINED OIL OF NON-MINERAL OR SYNTHETIC ORIGIN, ITS USE, COMPOSITION FOR PERSONAL CARE, COSMETICS, FOOD COMPOSITION, PHARMACEUTICAL COMPOSITION, COMPOSITION FOR ANIMAL CARE AND COMPOSITION OF OUR MEASURES TO MEASURES AND UNDERSTANDINGS FOR MEASURES AND MEASURES. EXTRAR REFINED FROM NON-MINERAL OR SYNTHETIC ORIGIN. Technical Field [001] The present invention relates to an oil which does not derive from an extrarrefined mineral or synthetic source, with high antioxidative stability, with the potential to be a substitute for mineral oil or oil of synthetic origin, currently used on a large scale, while providing greater stability compared to refined vegetable oil of food standard (food grade), in addition to, as a rule, having more accessible costs.

[002] The present invention aims, in particular, the application of oil of non-mineral or synthetic extrarrefined origin in personal care, cosmetic, food, pharmaceutical, animal or home care compositions.

Description of the State of the Art [003] Among the oils considered as not being derived from a mineral or synthetic source, the most commonly used is vegetable oil.

[004] Vegetable oils have been known for a long time and their applications are diverse, varying from the food, cosmetic, animal, home and even being used in the pharmaceutical area.

[005] Oils are part of the family of lipids, more precisely the group of glycerides, which fits both oils, liquids at room temperature, and fats, solid at the time6 / 45

2/25 ambient rature.

[006] Vegetable oils are extracted from different raw materials, and each source generates oils with particular properties according to the concentration of each fatty acid present in its composition.

[007] Thus, vegetable oils are a renewable source with several possibilities of application.

[008] Vegetable oils are natural, therefore, they do not harm the environment and can mimic the lipid composition of the skin and hair, this characteristic makes vegetable oils easily absorbed. They promote the protection of the skin against the excessive loss of water and nutrients, without interfering with the natural functions of the skin, they also help in the hydration and structure of the tissues.

[009] However, a major barrier currently found for the use and application of vegetable oils is their oxidative stability.

[0010] The extraction and purification process of a standard food grade oil, that is, an oil with acceptable characteristics for application in food, which is the oil of greatest use due to its cost / benefit ratio, brings with it elements and traits that act as catalysts for oil oxidation. One can mention as an example of these elements sterols, metals, aldehydes, ketones and peroxides, the latter formed by the natural degradation of the oil during the mentioned processes.

[0011] It is important to note that food grade or food grade oil is understood to mean one that comprises only substances known to be safe for food use in its composition, in addition to respecting the maximum percentages of these components described in the composition. In addition, the term food grade or food grade is widely used in the field of oils and is therefore well known to a person skilled in the art.

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3/25 [0012] Therefore, products that use vegetable oils generally have a short shelf life (1 year on average, including their performance in the final application), causing problems such as loss of active properties of the formulations, instability in formulations such as phase separation and organoleptic changes, in the medium or long term, compromising even the quality of the products.

[0013] Therefore, the use of this oil is restricted to products with reduced shelf life (food products that inherently have a shorter shelf life), or else they need the addition of large amounts of antioxidants to improve stabilization, which is not desirable in a base ingredient of a formulation, as it greatly restricts the possibility of adding other components necessary for the manufacture of a final product ready for consumption.

[0014] In addition, antioxidants have a limited shelf life after which they are degraded and lose their ability to capture electrons, thus losing their effect. Furthermore, the by-products of the degradation of antioxidants are often undesirable, as they alter the main properties and activities of the formulations and even alter the organoleptic characteristics of the product, such as texture, color and odor.

[0015] Especially in the area of personal care and cosmetics, the oil most commonly used is food grade oil, which has an acceptable degree of refining for the category. However, the use of vegetable oil is restricted by the points discussed above when applied in more complex formulations. The oxidation of vegetable oil, together with the degradation of added antioxidants to maintain its stability, end up causing the product to acquire the aforementioned undesirable characteristics, and even lose its

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4/25 effect after a relatively short period of shelf life.

[0016] The same occurs in other areas, such as pharmaceutical, animal health and care, human health and nutrition, home care and even in the food industry itself.

[0017] For this reason, the industries currently prefer the use of mineral oils, nonpolar, silicones, synthetic esters, since these have a longer shelf life, preserving the desirable characteristics of the product for a longer time.

[0018] However, several studies have shown the harmful effects of using mineral oils in products for human or animal application and, in addition, it was found that mineral oil, when exposed to high temperature, around 80 ° C, can degrade, generating by-products that are even more harmful to health.

[0019] Mineral oil is linked to the category of comedogenic products. The comedogenicity scale measures the ability of an ingredient to clog pores and ranges from 0 to 5, so the lower the comedogenic value of an oil (as well as any other substance), the more easily absorbed by the skin and the less comedogenic it is, in other words, less likely to cause acne and blackheads and comedones on the skin.

[0020] Mineral oil has no nutritional value, is not absorbed by the skin and hair and also does not promote hydration. In fact, it only lubricates the dermis superficially, prevents water loss and gives a false feeling of hydration. Because it is inert and does not dissolve in water or alcohol, mineral oil accumulates in the skin and hair and this accumulation makes the face lose its luster and the hair becomes heavy, without balance, in addition to hindering the absorption of other essential substances for the skin and hair health.

[0021] Some references that mention the harmful effects of mineral oil are the documents: AOEC (Association of Oc9 / 45

5/25 cupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation, EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry, FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: The Food Additive Database. FDA Office of Food Safety and Applied Nutrition and NLM (National Library of Medicine). 2006. HazMap - Occupational Exposure to Hazardous Agents.

[0022] Another important factor refers to ecotoxicity and biodegradability, since oils of mineral origin are not biodegradable and can potentially pollute the environment in addition to being from a non-renewable source.

[0023] For this reason, there remains a need to develop clean label products, that is, products that do not use only raw materials from natural renewable sources.

[0024] The present invention provides an oil for application in compositions in the area of personal care, cosmetics, food, pharmaceuticals, for the care of animals or the home, said oil being derived from a dissipation process that eliminates or significantly reduces the catalyst components degradation, significantly increasing its stability, without losing the intrinsic characteristics of the oil, greatly reducing, or even eliminating, the need to use antioxidants in the oil.

[0025] The present invention also has the advantage of the fact that extra-refined vegetable oil has the same composition as food grade vegetable oil, and, therefore, facilitating its replacement in the industrial plant given the need for no major adjustments to the process. [0026] Additionally, this fact also facilitates the regularization of products in the regulatory bodies, as the oils can be considered identical.

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Objectives of the Invention [0027] It is a first objective of the present invention to provide a highly stable oil, replacing the mineral oil or food grade oil currently used in several applications.

[0028] It is a second objective of the present invention to use oil in the preparation of compositions for personal, cosmetic, food, pharmaceutical, animal or home care.

[0029] It is a third objective of the present invention to provide a personal care, cosmetic composition.

[0030] It is a fourth objective of the present invention to provide a food composition.

[0031] It is a fifth objective of the present invention to provide a pharmaceutical composition.

[0032] It is a sixth objective of the present invention to provide a composition for animal care.

[0033] It is a seventh objective of the present invention to provide a composition for home care.

[0034] Finally, it is an eighth objective of the present invention to provide a product containing said oil.

Brief Description of the Invention [0035] The first objective of the present invention is achieved by means of an extrarrefined non-mineral or synthetic oil that has a dissipation factor varying, at most, 0.20% at 25 ° C, 3.60 % at 90 ° C and 4.0% at 100 ° C.

[0036] The second objective of the present invention is achieved through the use of extra-refined oil, as defined herein, for the preparation of a composition for personal, cosmetic, food, pharmaceutical, animal or home care.

[0037] The third objective of the present invention is achieved by means of a composition for personal care, cosmetic, with 11/45

7/25 comprising said extra-refined oil and a cosmetically acceptable vehicle.

[0038] The fourth objective of the present invention is achieved by means of a food composition, comprising said extra-refined oil and one or more acceptable food-grade excipients selected from water, alcohols, oils, vegetable fats, glycerin, natural and synthetic esters, maltodextrin , polyols, glucose, glucose, propylene glycol, native and modified starches, anionic, cationic, nonionic surfactants, emulsifiers of all kinds and HLBs, natural, synthetic or polymeric, thickeners and texturizers of natural origin (hydrocolloids) or synthetic, as well as any other components not described above, but which will perform such activity.

[0039] The fifth objective of the present invention is achieved by means of a pharmaceutical composition, comprising said extrarrefined oil and one or more pharmaceutically acceptable excipients selected from water, alcohols, oils, glycerin, natural and synthetic esters, maltodextrin, polyols, glucose, glucose, propylene glycol, native and modified starches, anionic, cationic, non-ionic surfactants, emulsifiers of all kinds and natural and synthetic or polymeric HLBs, thickeners and texturizers of natural origin (hydrocolloids) or synthetic, active for sun protection (physical filters and chemicals), dermatological actives (anti-aging, whitening, rejuvenating, cationic polymers, reducing agents or hair oxidizer). [0040] The sixth objective of the present invention is achieved by means of a composition for animal care, comprising said extrarrefined oil and one or more pharmaceutically acceptable excipients selected from water, alcohols, oils, glycerin, natural and synthetic esters, maltodextrin, polyols, glucose, glucose, propylene glycol, native and modified starches, anionic, cationic surfactants,

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8/25 non-ionic, emulsifiers of all kinds and HLBs (natural and synthetic or polymeric, thickeners and texturizers of natural origin (hydrocolloids) or synthetic, active for sun protection (physical and chemical filters), dermatological actives (anti-aging, whitening, rejuvenating, cationic polymers, reducing agents or hair oxidizer).

[0041] The seventh objective of the present invention is achieved by means of a composition for home care, comprising said extra-refined oil and one or more chemically acceptable excipients selected from water, alcohols, oils, glycerin, natural and synthetic esters, maltodextrin, polyols , glucose, glucose, propylene glycol, native and modified starches, anionic, cationic, nonionic surfactants, emulsifiers of all kinds and HLBs (natural and synthetic or polymeric, thickeners and texturizers of natural origin (hydrocolloids) or synthetic, active for sun protection (physical and chemical filters), dermatological actives (anti-aging, whitening, rejuvenating, cationic polymers, reducing agents or hair oxidizer).

[0042] Finally, the eighth objective of the present invention is achieved by means of a product comprising an extra-refined oil as defined herein, this product being, preferably, a composition for personal care, cosmetic, food, pharmaceutical, for animal or animal care. home.

Brief description of the figures [0043] The following is a brief description of the figures:

[0044] Figure 1 - Comparative curve of Oxidation Induction Time (OIT) analysis by Differential Scanning Calorimetry (DSC) for several oil samples.

[0045] Figure 2 - Comparative curve of Oxidation Onset Temperature (OOT) analysis by Var13 / 45

9/25 Differential Calorimetry (Differential Scanning Calorimetry DSC) for oil samples with respect to the time to start oxidation (figure 2a) and the temperature to start oxidation (figure 2b). [0046] Figure 3 - Quantification of peroxide generation by time for food grade oil samples, with and without antioxidants, compared to oil samples of the invention, with and without antioxidants.

[0047] Figure 4 - Schematic flowchart representing the chemical and physical processes of refining a food grade oil.

[0048] Figure 5 - Comparative Curve of Oxidation Induction Time (OIT) by Differential Scanning Calorimetry (DSC) for body lotion samples.

[0049] Figure 6 - Comparative Curve of Oxidation Induction Time (OIT) by Differential Scanning Calorimetry (DSC) for hair conditioner samples.

[0050] Figure 7 - Oxidation Induction Time (OIT) comparative curve by Differential Scanning Calorimetry (DSC) for oil samples mixed with BZC.

Detailed Description of the Invention [0051] The present invention relates to an extra-refined oil, hereinafter also called the oil of the invention.

[0052] Oil is all glyceride from plants that are liquid at room temperature, regardless of their method of extraction.

[0053] In addition, the methods of extracting vegetable oils are widely known in the state of the art and well known to those skilled in the subject.

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10/25 [0054] The oils used in the present invention are preferably, but not restricted to, any oil selected from the plant, animal, fungi, monera or protist kingdom, including fats, butters and / or any lipid compositions containing the previous combinations, including, among others, soybean oil, sunflower, canola, cotton, palm and derivatives, flaxseed, corn, sesame, babassu, cocoa, chia, tallow, lipids from fermentation processes.

[0055] As already mentioned, vegetable oils bring from their extraction and purification processes several components that act as catalysts for their oxidation.

[0056] Thus, for medium or long term applications, it is necessary to add high concentrations of antioxidants which ends up generating additional costs and undesired effects, especially considering that this is a base product for several compositions, these which often require the addition of other antioxidants, and are therefore always very close to the maximum allowed by legislation.

[0057] Vegetable oils are subjected to refining or purification processes so that they reach the standards necessary for their acceptance in food, pharmaceutical or cosmetic use. Currently, the oil most commonly produced is that of a food grade standard.

[0058] The traditional refining process can take place by chemical or physical means, which are as follows.

[0059] The chemical refining process has essentially 4 stages: (a) degumming; (b) neutralization; (c) clarification; and (d) deodorization. Each step is responsible for the partial removal of impurities. Since, at the end of the deodorization process, there is the refined oil of food grade or food grade.

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11/25 [0060] The physical process has only 3 stages: (a) degumming; (b) clarification; and (c) steam refining. Likewise, at the end of the steam refining stage, there is food grade oil.

[0061] As a technician in the subject knows, each step has the purpose of extracting certain substances present in the oil. More specifically, the degumming step removes phosphatides and solids, the neutralization step removes free fatty acids, metals (Ca + 2, Mg + 2, Fe + 2, Cu + 2, etc.) and pigments, the clarification step removes pigments, soaps, metals and contaminants, the winterization step removes waxes, sterols and saturated fatty acids and, finally, the deodorization step removes pigments, free fatty acids, pesticides and tocopherols.

[0062] The processes are schematically represented in figure 4 for better visualization.

[0063] The oil refining processes end in the steps above. On the other hand, the present invention goes beyond the traditional process.

[0064] After obtaining the refined oil or food grade, the present invention makes use of an extrarrefining process, in which super-absorbent particles are applied, for example, the filtering earth or the synthetic hydrated magnesium silicate, which adsorb the impurities that then they are removed by simple filtration, and are therefore responsible for removing said impurities from the oil.

[0065] Impurity means any substance that is not a fatty acid and acts as a possible electron conductor, especially sterols, metals, phospholipids and peroxides, which are catalysts of the oil oxidation process. These impurities are intrinsic substances in vegetable oils or have been added, directly or indirectly, by extraction and purification processes.

[0066] Alternatively, extrarrefining can also be performed

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12/25 by methods that are capable of separating the impurities present in the oil, for example, chromatography or extrafiltration processes. [0067] The use of super-absorbent particles is preferred because it is more economically viable on an industrial scale. The other extra-refining methods generate excessive expenses in the production process and, therefore, would end up greatly increasing the added value of the final product.

[0068] As it is a physical process without the use of high temperatures or pressures, the extrarrefining carried out in the present invention has the characteristics of keeping the concentration of fatty acids in the oil unchanged and, thus, preserves the intrinsic characteristics of the oil, therefore being able to be replaced directly without the need for relevant adjustments to the production line.

[0069] Additionally, this fact also facilitates the regularization of products in the regulatory bodies, as the oils can be considered structurally identical in relation to the fatty acid content.

[0070] The oil obtained by the above process can be characterized by its dissipation factor or power factor. Traditional methods such as quantification of acidity or peroxides by rancimat are not sufficient to differentiate between a fresh oil of the invention and a fresh food grade oil since the composition of fatty acids is identical. [0071] In addition, the rancimat test has the characteristic of generating peroxides by the equipment itself, which can alter the results obtained and, given the need for high precision, rancimat is not suggested for differentiating the oil from the invention of the oil food grade.

[0072] The preferred method for the evaluation of the oil of the invention is, as mentioned above, the measurement of its dissipation factor, or, in addition, its analysis by Differential Scanning of

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Differential scanning calorimetry - DSC.

[0073] The DSC analysis methodology can be divided into 2 main methods, the Oxidation Induction Time (OIT) and Oxidation Onset Temperature - OOT.

[0074] In the OIT method, the samples are heated under a protective condition, either inert gas or pressure, in this case pressure, at a constant temperature for several minutes until an equilibrium is established. Subsequently, the samples are exposed to oxygen or air. The measured time is that between the contact of the sample with oxygen or air until the beginning of oxidation.

[0075] The OOT method is a dynamic method, where the samples are heated at a constant rate and oxidizing conditions until oxidation begins.

[0076] Therefore, the extrarrefined oil of the present invention has as its peculiar characteristic a dissipation factor of, at most 0.20% at 25 ° C, 3.60% at 90 ° C and 4.0% at 100 ° C , measured under the standard methodology ABNT NBR 12133.

[0077] Once the catalysts are removed from the oil oxidation process, it acquires much greater stability, even without the addition of antioxidants.

[0078] Thus, the oil becomes plausible in applications that currently find it very difficult to use the oil to replace mineral oil, due to the problems of rapid oxidation and consequent loss of property of the products.

[0079] In particular, it was observed that the oil of the invention can be applied to products in the area of personal care, cosmetics, food, pharmaceuticals, animal or home care, replacing mineral oil or food grade, which currently represents the vast majority of the application.

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Thus, the present invention also relates to the use of oil, as defined herein, for the preparation of a composition, preferably a composition in the area of personal care, cosmetic, food, pharmaceutical, for animal care. and home.

[0081] It also refers to personal care, cosmetic, food, animal and home care compositions.

[0082] Said personal care, cosmetic composition, additionally also comprises at least one cosmetically acceptable vehicle and, optionally, a natural or synthetic antioxidant agent and / or combinations thereof.

[0083] Said cosmetically acceptable vehicle is preferably at least one selected from the group comprising water, alcohols, oils, glycerin, natural and synthetic esters, maltodextrin, polyols, glucose, glucose, propylene glycol, native and modified starches, anionic surfactants, cationic, non-ionic, emulsifiers of all kinds and natural and synthetic or polymeric hydrophilic / lipophilic balance (HLBs), thickeners and texturizers of natural origin (hydrocolloids) or synthetic, active for sun protection (physical and chemical filters), dermatological actives ( anti-aging, whitening, rejuvenating, cationic polymers, hair reducing or oxidizing agents, hydrogen peroxide, organic and inorganic acids).

[0084] The said antioxidant is preferably selected from the group comprising natural and synthetic antioxidant molecules, including butylated hydroxytoluene (BHT), butylated hydroxyanisole (BHA), tertiary hydroquinone (TBHQ), its derivatives and triazinnas, for example, Tinogard TL .

[0085] Said food composition additionally comprises one or more excipients of acceptable food grade, among which, optionally be water, alcohols, oils, vegetable fats, glycerin, natural and synthetic esters, maltodextrin, polyols, glucose, glucose,

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15/25 propylene glycol, native and modified starches, anionic, cationic, nonionic surfactants, emulsifiers of all kinds and natural and synthetic or polymeric HLBs, thickeners and texturizers of natural origin (hydrocolloids) or synthetic, organic and inorganic acids, and / or products of animal origin.

[0086] Said pharmaceutical composition further comprises one or more pharmaceutically acceptable excipients selected from water, alcohols, oils, glycerin, natural and synthetic esters, maltodextrin, polyols, glucose, glucose, propylene glycol, native and modified starches, anionic, cationic surfactants , non-ionic, emulsifiers of all kinds and natural and synthetic or polymeric HLBs, thickeners and texturizers of natural origin (hydrocolloids) or synthetic, active for sun protection (physical and chemical filters), dermatological actives (anti-aging, whitening, rejuvenating) , cationic polymers, reducing agents or hair oxidizer).

[0087] Said animal care composition additionally comprises one or more pharmaceutically acceptable excipients selected from water, alcohols, oils, glycerin, natural and synthetic esters, maltodextrin, polyols, glucose, glucose, propylene glycol, native and modified starches, anionic surfactants , cationic, non-ionic, emulsifiers of all kinds and HLBs (natural and synthetic or polymeric, thickeners and texturizers of natural origin (hydrocolloids) or synthetic, active for sun protection (physical and chemical filters), dermatological active (anti-aging, whitening, rejuvenating, cationic polymers, reducing agents or hair oxidizer).

[0088] Said home care composition additionally comprises one or more chemically acceptable excipients selected from water, alcohols, oils, glycerin, natural and synthetic esters, maltodextrin, polyols, glucose, glucose, propylene glycol, native and modified starches, surfactants anionic, cationic, nonionic, emul20 / 45

16/25 Zionists of all types and HLBs (natural and synthetic or polymeric, thickeners and texturizers of natural origin (hydrocolloids) or synthetic, active for sun protection (physical and chemical filters), dermatological active (anti-aging, whitening, rejuvenating) , cationic polymers, reducing agents or hair oxidizer).

[0089] Finally, the present invention also relates to a product comprising said extrarrefined oil of non-mineral or synthetic origin, where this product is, in a preferred embodiment, a personal care, cosmetic, food, pharmaceutical composition, for animal or home care.

Examples [0090] It is important to note that the examples below were conducted using soybean oil, hereinafter called oil, but the application of any oil of origin from the vegetable, animal, monera, protista or fungi kingdoms, and / or their combinations, it's possible.

[0091] The choice of oil to be applied is made by a technician on the subject who, based on the fatty acid content characteristic of each oil, has the ability to predict the best field for its application. Composition of extrarrefined soybean oil - ASTM D924 Methodology [0092] Crude soybean oil was purified using the conventional method as already described, being subjected to the steps of: (a) degumming; (b) neutralization; (c) clarification; and (d) deodorization, to obtain oil in the food grade standard.

[0093] The food grade oil was then subjected to extrarrefining by adding an adsorbent material, more specifically synthetic hydrated magnesium silicate, to remove the remaining impurities. Gas chromatography was carried out to verify whether the extrarrefining process would cause a change in the composition of the soy oil. Chromatography was performed using the Cc725 AOCS methodology.

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17/25 [0094] The main constituents of soybean oil are palmitic, oleic and linoleic acids. The results are shown in table 1 below.

Table 1 - Concentration of the main fatty acids from samples of natural and extrarrefined soybean oil

Natural Oil Extrarrefined Oil Palmitic acid 11.04% 10.94% Oleic acid 26.17% 25.67% Linoleic acid 50.36% 51.54%

[0095] As can be seen, the concentration of the main fatty acids that make up and characterize soybean oil, palmitic acid, oleic acid and linoleic acid, have no significant changes. Although not mentioned, there was also no significant change in the concentration of other fatty acids that make up soybean oil.

[0096] Therefore, a great advantage of the invention is that the extra-refined oil, in addition to the great acquired stability, keeps the fatty acid composition unchanged, conserving the properties of the oil.

Oxidation Induction Time - OIT [0097] To test the stability of the soybean oil of the present invention, the Oxidation Induction Time (OIT) test was performed using the DSC2920 - TA instruments - equipment Differential Scanning Calorimetry - DSC, where the time that each oil sample starts to oxidize at a constant temperature, in this case 130 ° C, is determined. The methodology used was the standard for OIT analysis of oils, EN 14112 (European standard).

[0098] It is important to note that the DSC was particularly chosen since the traditional technique for assessing oxidation via rancimat is subject to the interference of free radicals formed by

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18/25 method and, therefore, does not have sufficient sensitivity for the purposes of the present invention.

[0099] The tested samples sought to compare expired traditional vegetable oils (old samples), fresh traditional vegetable oils (new), the oil of the present invention (Ultra-oil - UT) old and fresh and the standard mineral oil. Vegetable oils, traditional and from the invention, were also tested with the addition of antioxidant, in this case butylated hydroxytoluene (BHT), at a concentration of 100ppm. [00100] Some samples were even subjected to stress conditions to simulate a longer shelf life.

[00101] Stress induction consists of heating the sample to 250 ° C, so it is expected that the sample is cooled to 100 ° C so that it is again heated to 250 ° C. This methodology is frequently used in the cosmetic area in order to evaluate the behavior of oils in their final formulations.

[00102] The data obtained are illustrated in figure 1 and the table below.

Table 2 - ILO results for oil samples

Number of Sample Sample Time 1 Vegetable Oil from the Old Sample 21.61 2 Vegetable oil Fab. Jun 16 25.99 3 Vegetable oil with BHT Jun 16 30.32 4 New Stress Vegetable Oil 13.11 5 New vegetable oil Stress BHT 19.63 6 Old vegetable oil with BHT 28.48 7 Fresh vegetable oil 25.98 8 Fresh vegetable oil with BHT 28.80 9 Fresh vegetable oil with BHT - Stress 21.06 10 Old UT vegetable oil 27.64 11 UT Old Vegetable Oil with BHT 30.75

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Number of Sample Sample Time 12 UT Fresh Vegetable Oil 27.71 13 UT Fresh Vegetable Oil with BHT 30.56 14 UT Fresh Vegetable Oil with BHT - Stress 26.48 15 Mineral oil 40.00

[00103] As can be seen, there is a significant difference between the oxidation onset time (onset) of the expired oil compared to the oil of the present invention. More precisely, the onset of the expired oil was only 21.61 minutes, while the control of the oil of the invention and the oil of the invention with antioxidant after stress have an onset of 27.71 and 26.48 minutes, respectively. [00104] Furthermore, it is still possible to observe that even after the simulation of 1 year of shelf life (stress procedure), the oil of the invention maintained an onset very close to the fresh oil, thus demonstrating its high stability given its resistance to oxidation.

[00105] In order to better visualize the results obtained by the present invention, a comparative graph was also drawn up between samples 4, 13, 12 and 15, as shown in figure 2, where the improvement in the OIT time obtained by the oil of the present is evident invention. Oxidation Onset Temperature - OOT [00106] In order to corroborate the above results, an Oxidation Onset Temperature (OOT) test was also performed on DSC. The methodology used was the standard for OOT analysis of oils, EN 14112 (European standard).

[00107] Unlike the OIT test, where the temperature is unique from the beginning, in this test the temperature is gradually increased in order to measure at which temperature the samples begin to oxidize.

[00108] The same 4 samples compared above, samples 4, 13,

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20/25 and 15 were tested.

[00109] The results obtained are shown in Figures 2a and 2b and in the table below.

Table 3 - OOT results of oil samples

Sample number Time (min) Temperature ° C 4 18.12 94.83 13 20.79 166.78 12 20.47 163.88 15 25.06 188.36

[00110] As expected, the expired oil (sample 4) is the one with the lowest oxidation time and temperature (onset), 18.12 min and 94.83 ° C, respectively. It is also possible to observe that the samples of the oil of the invention (samples 13 and 12) have significantly larger onsets in comparison with the expired oil, and are even close to mineral oil (sample 15).

Peroxide Quantification [00111] Finally, to ensure that the stability of the oil of the invention is associated with its ability to prevent the generation of free radicals responsible for its oxidation, the peroxide generation of (1) control oil ( food grade), (2) control oil with antioxidant, (3) oil of the invention and (4) oil of the invention with antioxidant BHT at a concentration of 100 ppm. The methodology used followed the AOCS Cb 8b-90 protocol. The results are shown in figure 3.

[00112] As can be seen, the results obtained corroborate the other results, demonstrating that the control oil without antioxidants is the one with the highest production of peroxides and the oil of the invention with the addition of antioxidants has the lowest.

[00113] It is also important to note that the oil of the invention without antioxidants has a statistically identical result to the control oil with the addition of antioxidants. In other words, the oil of the invention, even

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21/25 without the addition of antioxidants, it achieves the same effects as the control oil with antioxidants, thus demonstrating its stability.

Tests on final products [00114] In order to verify whether the better stability properties of the oil of the present invention would be reflected in finished products that make use of this, tests were carried out by incorporating the oil of the present invention in a body lotion and in a hair conditioner as below.

[00115] Still, despite the DSC being routinely used only for the evaluation of raw materials, and not for final formulations that include several components, the use of the same methodology and the same equipment enabled a comparison of results between oils and products where these were applied.

Body lotion test - Skin care compositions [00116] Non-ionic body lotion formulations were prepared using different samples of vegetable oils.

[00117] The body lotion formulations all followed the composition of: 0.10% ethylenediamine tetraacetic acid (EDTA), 5.00% Olivem® 1000, 1.00% PEHG (phenoxyethanol and ethylhexylglycerine), 10 , 00% of oil and deionized water qsp 100.

[00118] The oils used were: sample 4 (traditional oil after stress) as a negative control, sample 13 (UT with and without BHT - Antioxidant) to represent the present invention and sample 15 (mineral oil) as a positive control.

[00119] The compositions are illustrated in table 4 below. Table 4 - Body lotion formulations tested

Code of Sample Number of oil sample Used Oil F 4 New Stress Vegetable Oil H 13 UT Fresh Vegetable Oil with BHT J 15 Mineral oil

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22/25 [00120] In a first ILO test performed with samples F, H and J above, none of the samples showed degradation up to 40 minutes.

[00121] In this sense, an extraction process was carried out in order to accelerate the oxidation process.

[00122] Said extraction process consists of mixing the formulations F to J, in a ratio of 1: 1 with the oil used. For example, in sample F, 2.5 g of formulation F were mixed for 3 minutes with 2.5 g of new vegetable oil Stress and then the mixture was allowed to stand for 12 hours.

[00123] The same process was carried out for formulations H and J, giving rise to samples K, L and M according to table 5 below.

Table 5 - Body lotion formulations with accelerated oxidation

Sample Code Formulation K Sample F + New Stress Vegetable Oil (1: 1) L Sample H + UT Fresh Vegetable Oil with BHT (1: 1) M Sample J + mineral oil (1: 1)

[00124] The OIT test was then performed for samples K, L and M. The results obtained are shown in figure 5 and table 6 below. Table 6 - OIT test result for samples K, L and M

Sample Code ILO - Onset time - min K 14.95 L 29.40 M There was no degradation until the time of 100.00

[00125] As expected, the OIT test of samples K, L and M revealed a longer Onset time (onset of oxidation) for the sample referring to the present invention, thus proving its better stability in the final product, compared to oil traditional vegetable.

[00126] Also, the comparison of organoleptic characteristics between formulations K and L showed that formulation K presented mi27 / 45

23/25 phase growth, as well as yellowing and odor, more prominently when compared to formulation L. Hair conditioner test - Hair care compositions [00127] Hair conditioner formulations were prepared_using different samples of vegetable oils.

[00128] The body lotion formulations all followed the composition of: 0.10% EDTA, 5.00% Olivem 1000, 1.00% PEHG Preservative, 2.00% cationic surfactant Benzalkonium Chloride (BZC) , 10.00% oil and deionized water qsp 100.

[00129] The oils used were: sample 4 (traditional oil after stress) as a negative control, sample 13 (UT with BHT) to represent the present invention and sample 15 (mineral oil) as a positive control.

[00130] The compositions are illustrated in table 7 below. Table 7 - Conditioner formulations for tested hair

Sample Code Oil sample number Used Oil O 4 New Stress Vegetable Oil P 13 UT Fresh Vegetable Oil with BHT Q 15 Mineral oil

[00131] In a first ILO test performed with samples O, P and Q above, none of the samples showed degradation up to 40 minutes.

[00132] In this sense, an extraction process was carried out in order to accelerate the oxidation process.

[00133] Said extraction process consists of mixing the formulations F to J, in a ratio of 1: 1 with the oil used. For example, in sample O, 2.5 g of formulation O were mixed for 3 minutes with 2.5 g of new vegetable oil Stress and then the mixture was allowed to stand for 12 hours.

[00134] The same process was carried out for formulations P and

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Q, giving rise to samples R, S and T as shown in table 8 below. Table 8 - Conditioner formulations for hair with accelerated oxidation

Sample Code Formulation R Sample O + New vegetable oil Stress (1: 1) s Sample P + UT Fresh Vegetable Oil with BHT (1: 1) T Sample Q + mineral oil (1: 1)

[00135] Additionally, solutions were formulated containing only the oil and BZC in the proportion of 2: 1 according to table 9 below.

Table 9 - Vegetable oil and BZC formulations

Sample Code Formulation U New vegetable oil Stress + BZC (2: 1) V UT Fresh Vegetable Oil with BHT + BZC (2: 1) X mineral oil + BZC (2: 1)

[00136] The OIT test was then performed for samples K, L and M. The results obtained are shown in figures 6 and 7 and in tables 10 and 11 below.

Table 10 - OIT test result for samples R, S and T

Sample Code ILO - OnSet time - min R 14.15 s 29.52 T There was no degradation until the time of 100.00

Table 11 - OIT test result for samples U, V and X

Sample Code ILO - OnSet time - min U 3.55 V 11.79 X There was no degradation until the time of 100.00

[00137] As expected, the OIT test of the samples above revealed a longer Onset time (onset of oxidation) for the sample referring to the present invention, thus proving its better stability in the final product, compared to traditional vegetable oil.

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25/25 [00138] Also, the comparison of organoleptic characteristics between formulations R and S showed that formulation R showed phase migration, yellowing and odor appearance, more prominently when compared to formulation S.

Determination of the Dissipation Factor [00139] The determination of the dissipation factor was carried out according to standard procedure ABNT NBR 12133, using the DTL C equipment.

[00140] The temperatures of 25, 90 and 100 ° C were used as parameters, in addition to a voltage of 500 VAC and a frequency of 60 Hz. [00141] It was observed that vegetable oil, when satisfactorily extrarrefined, it has a dissipation factor varying, at most, 0.20% at 25 ° C, 3.60% at 90 ° C and 4.0% at 100 ° C.

[00142] Having described examples of preferred embodiments, it should be understood that the scope of the present invention covers other possible variations, being limited only by the content of the appended claims, including possible equivalents therein.

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Claims (15)

1. Extra-refined oil of non-mineral or synthetic origin, characterized by the fact that it has a dissipation factor varying, at most, 0.20% at 25 ° C, 3.60% at 90 ° C and 4.0% at 100 ° C. 2. Extrarrefined oil, according to claim 1, characterized by the fact that it originates from the vegetable, animal, fungi, monera or protist kingdom, including fats, butters and / or any lipid compositions containing the previous combinations, comprising, among others , soybean oil, sunflower, canola, cotton, palm and derivatives, flaxseed, corn, sesame, babassu, cocoa, chia, tallow, lipids from fermentation processes. 3. Extra-refined oil according to any one of claims 1 and 2, characterized by the fact that it is obtained through an extrarrefining process. 4. Extrarrefined oil, according to claim 3, characterized by the fact that the process comprises the addition of superabsorbent particles, preferably of filtering earth or synthetic hydrated magnesium silicate, to remove the electron conducting components present in the lipid compositions. 5. Use of extra-refined oil, as defined in claims 1 to 4, characterized by the fact that it is for the preparation of a composition for personal, cosmetic, food, pharmaceutical, animal or home care. 6. Personal care, cosmetic composition, characterized by the fact that it comprises an extra-refined oil as defined in any one of claims 1 to 4, and a cosmetically acceptable vehicle. 7. Composition according to claim 6, characterized by the fact that the cosmetically acceptable vehicle is selected from water, alcohols, oils, glycerin, natural and synthetic esters31 / 45 2/4 cos, maltodextrin, polyols, glucose, glucose, propylene glycol, native and modified starches, anionic, cationic, nonionic surfactants, emulsifiers of all kinds and natural and synthetic or polymeric HLBs, thickeners and texturizers of natural origin (hydrocolloids) or synthetic, active for sun protection (physical and chemical filters), dermatological actives (anti-aging, lightening, rejuvenating, cationic polymers, hair reducing or oxidizing agents, hydrogen peroxide, organic and inorganic acids). Composition according to claim 6, characterized in that it can additionally comprise an antioxidant agent. 9. Composition according to claim 8, characterized by the fact that the antioxidant is selected from the group consisting of natural and / or synthetic antioxidant molecules, or combinations thereof, including butylated hydroxytoluene (BHT), butylated hydroxyanisol (BHA), hydroquinone tertiary (TBHQ), its derivatives and triazinnas. 10. Food composition, characterized by the fact that it comprises an extra-refined oil as defined in any one of claims 1 to 4, and one or more acceptable food-grade excipients, among which, optionally be water, alcohols, oils, vegetable fats, glycerin, natural and / or synthetic esters, maltodextrin, polyols, glucose, glucose, propylene glycol, native and modified starches, anionic, cationic, non-ionic surfactants, emulsifiers of all kinds and natural and synthetic or polymeric, thickeners and texturizing HLBs of origin natural (hydrocolloids) or synthetic, organic and inorganic acids, and / or products of animal origin. 11. Pharmaceutical composition, characterized by the fact that it comprises an extra-refined oil as defined in qual32 / 45 3/4 or one of claims 1 to 4, and one or more pharmaceutically acceptable excipients selected from water, alcohols, oils, glycerin, natural and synthetic esters, maltodextrin, polyols, glucose, glucose, propylene glycol, native and modified starches, anionic surfactants , cationic, non-ionic, emulsifiers of all kinds and natural and synthetic or polymeric HLBs, thickeners and texturizers of natural origin (hydrocolloids) or synthetic, active for sun protection (physical and chemical filters), dermatological actives (antiaging, whitening, rejuvenating) , cationic polymers, reducing agents or hair oxidizer). 12. Animal care composition, characterized in that it comprises an extra-refined oil as defined in any of claims 1 to 4, and one or more pharmaceutically acceptable excipients selected from water, alcohols, oils, glycerin, natural and synthetic esters, maltodextrin , polyols, glucose, glucose, propylene glycol, native and modified starches, anionic, cationic, nonionic surfactants, emulsifiers of all kinds and HLBs (natural and synthetic or polymeric, thickeners and texturizers of natural origin (hydrocolloids) or synthetic, active for sun protection (physical and chemical filters), dermatological actives (anti-aging, whitening, rejuvenating, cationic polymers, reducing agents or hair oxidizer). 13. Home care composition, characterized by the fact that it comprises an extra-refined oil as defined in any of claims 1 to 4, and one or more chemically acceptable excipients selected from water, alcohols, oils, glycerin, natural and synthetic esters, maltodextrin, polyols, glucose, glucose, propylene glycol, native and modified starches, anionic, cationic, non-ionic surfactants, emulsifiers of all kinds and HLBs (natural and synthetic or polymeric, thickeners and texturizers) 33/45 4/4 of natural origin (hydrocolloids) or synthetic, active for sun protection (physical and chemical filters), dermatological actives (anti-aging, bleaching, rejuvenating, cationic polymers, reducing agents or hair oxidizer). 14. Product, characterized by the fact that it comprises an extra-refined oil of non-mineral or synthetic origin as defined in any one of claims 1 to 4. 15. Product according to claim 14, characterized by the fact that it is a composition for personal care, cosmetic, food, pharmaceutical, for animal or home care. 34/45 1/6 ο Q. Ε ω ι— {