BR102015019724A2 - projeto de sensor de papel - Google Patents
projeto de sensor de papel Download PDFInfo
- Publication number
- BR102015019724A2 BR102015019724A2 BR102015019724A BR102015019724A BR102015019724A2 BR 102015019724 A2 BR102015019724 A2 BR 102015019724A2 BR 102015019724 A BR102015019724 A BR 102015019724A BR 102015019724 A BR102015019724 A BR 102015019724A BR 102015019724 A2 BR102015019724 A2 BR 102015019724A2
- Authority
- BR
- Brazil
- Prior art keywords
- test
- test zones
- area
- axially
- paper sensor
- Prior art date
Links
- 238000013461 design Methods 0.000 title abstract description 9
- 238000012360 testing method Methods 0.000 claims abstract description 155
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 26
- 230000004888 barrier function Effects 0.000 claims abstract description 17
- 239000012530 fluid Substances 0.000 claims abstract description 17
- 239000012620 biological material Substances 0.000 claims abstract description 13
- 239000003973 paint Substances 0.000 claims abstract description 13
- 239000012528 membrane Substances 0.000 claims description 14
- 238000000926 separation method Methods 0.000 claims description 11
- 239000000758 substrate Substances 0.000 claims description 7
- 239000005001 laminate film Substances 0.000 claims description 5
- 230000015572 biosynthetic process Effects 0.000 claims description 2
- 238000000034 method Methods 0.000 abstract description 14
- 239000008280 blood Substances 0.000 abstract description 10
- 210000004369 blood Anatomy 0.000 abstract description 10
- 230000008901 benefit Effects 0.000 abstract description 8
- 230000008569 process Effects 0.000 abstract description 6
- 210000002700 urine Anatomy 0.000 abstract description 4
- 210000003296 saliva Anatomy 0.000 abstract description 3
- 230000010354 integration Effects 0.000 abstract description 2
- 238000011002 quantification Methods 0.000 abstract 1
- 230000008859 change Effects 0.000 description 8
- 239000012491 analyte Substances 0.000 description 6
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 6
- 230000015654 memory Effects 0.000 description 5
- 230000003287 optical effect Effects 0.000 description 5
- 239000011148 porous material Substances 0.000 description 5
- 238000012545 processing Methods 0.000 description 5
- 108010010234 HDL Lipoproteins Proteins 0.000 description 4
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 4
- 239000003086 colorant Substances 0.000 description 4
- 238000004590 computer program Methods 0.000 description 4
- 230000002209 hydrophobic effect Effects 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 3
- 238000004166 bioassay Methods 0.000 description 3
- 238000010276 construction Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 230000001052 transient effect Effects 0.000 description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- 108010023302 HDL Cholesterol Proteins 0.000 description 2
- 102000001554 Hemoglobins Human genes 0.000 description 2
- 108010054147 Hemoglobins Proteins 0.000 description 2
- 239000013060 biological fluid Substances 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 235000012000 cholesterol Nutrition 0.000 description 2
- 238000007405 data analysis Methods 0.000 description 2
- 239000008103 glucose Substances 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 239000011159 matrix material Substances 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 238000010992 reflux Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 150000003626 triacylglycerols Chemical class 0.000 description 2
- 102000017011 Glycated Hemoglobin A Human genes 0.000 description 1
- 108010014663 Glycated Hemoglobin A Proteins 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 238000011948 assay development Methods 0.000 description 1
- 238000011088 calibration curve Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 231100001261 hazardous Toxicity 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 230000001678 irradiating effect Effects 0.000 description 1
- 238000003475 lamination Methods 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
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- 239000000463 material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000005055 memory storage Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
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- 239000007787 solid Substances 0.000 description 1
- 238000013517 stratification Methods 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/525—Multi-layer analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/069—Absorbents; Gels to retain a fluid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0803—Disc shape
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0887—Laminated structure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
- B01L2300/126—Paper
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/16—Surface properties and coatings
- B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
- B01L2300/165—Specific details about hydrophobic, oleophobic surfaces
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Clinical Laboratory Science (AREA)
- Plasma & Fusion (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Biophysics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462041174P | 2014-08-25 | 2014-08-25 | |
| US14/799,832 US9586204B2 (en) | 2014-06-23 | 2015-07-15 | Paper sensor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR102015019724A2 true BR102015019724A2 (pt) | 2016-03-01 |
Family
ID=54064130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR102015019724A BR102015019724A2 (pt) | 2014-08-25 | 2015-08-17 | projeto de sensor de papel |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9586204B2 (enExample) |
| EP (1) | EP2990118B1 (enExample) |
| JP (1) | JP6494033B2 (enExample) |
| KR (1) | KR102266347B1 (enExample) |
| CN (1) | CN105388143B (enExample) |
| BR (1) | BR102015019724A2 (enExample) |
| RU (1) | RU2698818C2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9933359B2 (en) * | 2014-06-23 | 2018-04-03 | Xerox Corporation | Vendor exclusivity security feature for paper-based diagnostic solution |
| WO2017122178A1 (en) * | 2016-01-14 | 2017-07-20 | King Abdullah University Of Science And Technology | Paper based electronics platform |
| NO341514B1 (en) * | 2016-04-15 | 2017-11-27 | Univ College Of Southeast Norway | Passive body fluid screening and analysis device for diapers, methods of realizing same, and methods of using same |
| WO2018140568A1 (en) * | 2017-01-27 | 2018-08-02 | Becton, Dickinson And Company | Vertical flow assay device for detecting glucose concentration in a fluid sample |
| EP3697537A4 (en) | 2017-10-18 | 2021-10-20 | Group K Diagnostics, Inc. | SINGLE-LAYER MICROFLUIDIC DEVICE AND ITS MANUFACTURING AND USE METHODS |
| CN108802402A (zh) * | 2018-06-15 | 2018-11-13 | 重庆大学 | 一种快速鉴别呼吸道感染类型的试剂盒及其应用 |
| KR102401909B1 (ko) * | 2018-08-30 | 2022-05-24 | 주식회사 엘지화학 | 반응 최적화를 위한 고속 스크리닝 분석 시스템 |
| USD879999S1 (en) | 2018-11-02 | 2020-03-31 | Group K Diagnostics, Inc. | Microfluidic device |
| BR112022002527A2 (pt) | 2019-08-29 | 2022-05-10 | Canon Kk | Método para produção de dispositivo de microcanal |
| CN110806489B (zh) * | 2019-10-15 | 2023-04-25 | 南京大树生物医疗技术股份有限公司 | 一种抗干扰的干化学联合检测装置 |
| WO2021092595A1 (en) * | 2019-11-07 | 2021-05-14 | Essenlix Corporation | Improvements of lateral flow assay and vertical flow assay |
| KR102169175B1 (ko) * | 2020-01-02 | 2020-10-22 | 박동진 | 간이 질병검진도구 |
| US20210231646A1 (en) * | 2020-01-28 | 2021-07-29 | Purdue Research Foundation | Multifluidic device and processing system for colorimetric multiplexed detection of a substance |
| RU200112U1 (ru) * | 2020-01-29 | 2020-10-07 | Федеральное государственное учреждение "Федеральный исследовательский центр "Фундаментальные основы биотехнологии" Российской академии наук" (ФИЦ Биотехнологии РАН) | Карта сравнения для количественной интерпретации результатов иммунохроматографических тестов |
| US11498069B2 (en) * | 2020-08-31 | 2022-11-15 | International Business Machines Corporation | Rapid testing device for wastewater analysis |
| US11618032B2 (en) * | 2020-08-31 | 2023-04-04 | International Business Machines Corporation | Multiplexed testing strip device |
| JP7748644B2 (ja) * | 2021-08-26 | 2025-10-03 | 島根県 | 味覚センサ用プローブ |
| US12140534B2 (en) | 2023-01-05 | 2024-11-12 | Sequitur Health Corp. | Devices, methods, and systems for deriving a permeate from a feed solution |
| US12030045B1 (en) * | 2023-01-05 | 2024-07-09 | Sequitur Health Corp. | Devices, methods, and systems for deriving ammonia gas from whole blood |
| WO2025143227A1 (ja) * | 2023-12-28 | 2025-07-03 | Ｚａｃｒｏｓ株式会社 | 反応性物質が塗布された反応部を備えた検査デバイス |
| PL450227A1 (pl) * | 2024-11-07 | 2025-07-14 | Politechnika Warszawska | Sposób wytwarzania obszarów kontrolnych przepływu cieczy w czujnikach typu lab-on-paper |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3891507A (en) * | 1974-05-30 | 1975-06-24 | American Cyanamid Co | Organ function test cards |
| US7373300B1 (en) | 2002-12-18 | 2008-05-13 | At&T Corp. | System and method of providing a spoken dialog interface to a website |
| US8200775B2 (en) | 2005-02-01 | 2012-06-12 | Newsilike Media Group, Inc | Enhanced syndication |
| US7972859B2 (en) * | 2006-06-27 | 2011-07-05 | Authentix, Inc. | Authentication of ingestible products using saccharides as markers |
| CN101578520B (zh) * | 2006-10-18 | 2015-09-16 | 哈佛学院院长等 | 基于形成图案的多孔介质的横向流动和穿过生物测定装置、及其制备方法和使用方法 |
| US7969624B2 (en) | 2006-12-11 | 2011-06-28 | Xerox Corporation | Method and system for identifying optimal media for calibration and control |
| JP4868409B2 (ja) * | 2007-05-29 | 2012-02-01 | 富士フイルム株式会社 | 検査シート |
| US7454880B1 (en) | 2007-05-31 | 2008-11-25 | Xerox Corporation | Personalized medication packaging |
| JP2009039350A (ja) * | 2007-08-09 | 2009-02-26 | Hitachi Chem Co Ltd | 血球分離材及び血球分離材の製造方法 |
| EP2257819A4 (en) | 2008-03-27 | 2017-10-11 | President and Fellows of Harvard College | Three-dimensional microfluidic devices |
| CN102016596B (zh) | 2008-03-27 | 2014-09-17 | 哈佛学院院长等 | 纸基微流体系统 |
| AU2010221117A1 (en) * | 2009-03-06 | 2011-09-29 | President And Fellows Of Harvard College | Methods of micropatterning paper-based microfluidics |
| WO2010102279A1 (en) | 2009-03-06 | 2010-09-10 | President And Fellows Of Harvard College | Microfluidic, electromechanical devices |
| CN102472745B (zh) * | 2009-06-30 | 2015-08-05 | 莫纳什大学 | 使用纸基微流体系统的定量和自校准化学分析 |
| US8821810B2 (en) | 2010-02-03 | 2014-09-02 | President And Fellows Of Harvard College | Devices and methods for multiplexed assays |
| BRPI1003876B1 (pt) | 2010-10-07 | 2019-12-03 | Cbr Participacoes Ltda | processo para produção de eletrodo com baixa teor de hidrogênio e baixa absorção de umidade |
| EP2681538B1 (en) * | 2011-03-11 | 2019-03-06 | Mc10, Inc. | Integrated devices to facilitate quantitative assays and diagnostics |
| US8730460B2 (en) | 2011-04-08 | 2014-05-20 | William Marsh Rice University | Paper based spectrophotometric detection of blood hemoglobin concentration |
| WO2012160857A1 (ja) * | 2011-05-20 | 2012-11-29 | 学校法人慶應義塾 | 紙ベース反応用チップ及びその製造方法 |
| US9354181B2 (en) * | 2011-08-04 | 2016-05-31 | Saint Mary's College | Analytical devices for detection of low-quality pharmaceuticals |
| EP2761279A4 (en) * | 2011-09-27 | 2015-08-12 | Diagnostics For All Inc | QUANTITATIVE MICROFLUIDIC DEVICES |
| US9557274B2 (en) * | 2012-08-17 | 2017-01-31 | St. Mary's College | Analytical devices for detection of low-quality pharmaceuticals |
-
2015
- 2015-07-15 US US14/799,832 patent/US9586204B2/en not_active Expired - Fee Related
- 2015-08-17 JP JP2015160364A patent/JP6494033B2/ja not_active Expired - Fee Related
- 2015-08-17 BR BR102015019724A patent/BR102015019724A2/pt not_active Application Discontinuation
- 2015-08-19 CN CN201510512555.9A patent/CN105388143B/zh active Active
- 2015-08-20 EP EP15181870.5A patent/EP2990118B1/en not_active Not-in-force
- 2015-08-21 RU RU2015135403A patent/RU2698818C2/ru active
- 2015-08-21 KR KR1020150117798A patent/KR102266347B1/ko active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP6494033B2 (ja) | 2019-04-03 |
| RU2015135403A3 (enExample) | 2019-03-25 |
| EP2990118A1 (en) | 2016-03-02 |
| JP2016045199A (ja) | 2016-04-04 |
| US9586204B2 (en) | 2017-03-07 |
| RU2015135403A (ru) | 2017-03-03 |
| KR102266347B1 (ko) | 2021-06-18 |
| EP2990118B1 (en) | 2018-04-25 |
| KR20160024780A (ko) | 2016-03-07 |
| CN105388143A (zh) | 2016-03-09 |
| CN105388143B (zh) | 2019-06-25 |
| RU2698818C2 (ru) | 2019-08-30 |
| US20160051980A1 (en) | 2016-02-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B03A | Publication of a patent application or of a certificate of addition of invention [chapter 3.1 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |