BR0302594A - Animais transgênicos expressando proteìna associada ao complexo de receptor andrógeno - Google Patents

Animais transgênicos expressando proteìna associada ao complexo de receptor andrógeno

Info

Publication number
BR0302594A
BR0302594A BR0302594-2A BR0302594A BR0302594A BR 0302594 A BR0302594 A BR 0302594A BR 0302594 A BR0302594 A BR 0302594A BR 0302594 A BR0302594 A BR 0302594A
Authority
BR
Brazil
Prior art keywords
transgenic animals
animals expressing
androgen receptor
receptor complex
associated protein
Prior art date
Application number
BR0302594-2A
Other languages
English (en)
Inventor
Tai-Jay Chang
Original Assignee
Taipei Veterans General Hospit
Targetgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taipei Veterans General Hospit, Targetgen Inc filed Critical Taipei Veterans General Hospit
Publication of BR0302594A publication Critical patent/BR0302594A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"ANIMAIS TRANSGêNICOS EXPRESSANDO PROTEìNA ASSOCIADA AO COMPLEXO DE RECEPTOR ANDRóGENO". A presente invenção refere-se aos animais transgênicos expressando um gene de proteína associada ao complexo do receptor andrógeno. Esses animais servem como modelos para desenvolvimento de drogas para tratar câncer, por exemplo, câncer de fígado.
BR0302594-2A 2002-07-25 2003-07-25 Animais transgênicos expressando proteìna associada ao complexo de receptor andrógeno BR0302594A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/206,566 US20030082721A1 (en) 2001-01-17 2002-07-25 Transgenic animals expressing androgen receptor complex-associated protein

Publications (1)

Publication Number Publication Date
BR0302594A true BR0302594A (pt) 2004-08-24

Family

ID=31886545

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0302594-2A BR0302594A (pt) 2002-07-25 2003-07-25 Animais transgênicos expressando proteìna associada ao complexo de receptor andrógeno

Country Status (7)

Country Link
US (1) US20030082721A1 (pt)
EP (1) EP1398323A1 (pt)
KR (1) KR20040010402A (pt)
CN (1) CN1495195A (pt)
BR (1) BR0302594A (pt)
RU (1) RU2333959C2 (pt)
TW (1) TWI344988B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2818478T3 (en) * 2011-10-28 2017-05-22 Regeneron Pharma HUMANIZED IL-6 AND IL-6 RECEPTOR
US10349638B2 (en) * 2017-07-14 2019-07-16 Tai-Jay Chang Human ARCAP transgenic mouse
WO2020140858A1 (en) * 2019-01-03 2020-07-09 Chen Show Li Method for treating amyotrophic lateral sclerosis

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5789170A (en) * 1996-05-23 1998-08-04 Wisconsin Alumni Research Foundation Specific co-activator for human androgen receptor
US6525187B1 (en) * 1998-07-31 2003-02-25 Diagnostic Products Corporation Polynucleotide encoding autoantigens associated with endometriosis
EP1196577A2 (en) * 1999-07-21 2002-04-17 Incyte Genomics, Inc. Cell cycle and proliferation proteins
US6974683B2 (en) * 2001-01-17 2005-12-13 Veterans General Hospital Nucleic acid encoding androgen receptor complex-associated protein
US20030099976A1 (en) * 2001-01-17 2003-05-29 Tai-Jay Chang Androgen receptor complex-associated protein
US6783969B1 (en) * 2001-03-05 2004-08-31 Nuvelo, Inc. Cathepsin V-like polypeptides

Also Published As

Publication number Publication date
KR20040010402A (ko) 2004-01-31
RU2333959C2 (ru) 2008-09-20
EP1398323A1 (en) 2004-03-17
TWI344988B (en) 2011-07-11
US20030082721A1 (en) 2003-05-01
RU2003123598A (ru) 2005-02-10
TW200407433A (en) 2004-05-16
CN1495195A (zh) 2004-05-12

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5O E 6O ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2042 DE 23/02/2010.