BR0300997A - Compostos arilidenotiazolidinadiÈnicos com atividade hipoglicêmica - Google Patents

Compostos arilidenotiazolidinadiÈnicos com atividade hipoglicêmica

Info

Publication number
BR0300997A
BR0300997A BR0300997-1A BR0300997A BR0300997A BR 0300997 A BR0300997 A BR 0300997A BR 0300997 A BR0300997 A BR 0300997A BR 0300997 A BR0300997 A BR 0300997A
Authority
BR
Brazil
Prior art keywords
compounds
hypoglycemic activity
thiazolidine
antidiabetic
arylidenethiazolidinedinic
Prior art date
Application number
BR0300997-1A
Other languages
English (en)
Inventor
Ivan Da Rocha Pitta
Maria Do Carmo Alves De Lima
Suely Lins Galdino
Jacques Honor Augustin Barbe
Original Assignee
Conselho Nacional Cnpq
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Conselho Nacional Cnpq filed Critical Conselho Nacional Cnpq
Priority to BR0300997-1A priority Critical patent/BR0300997A/pt
Priority to PCT/BR2004/000053 priority patent/WO2004089276A2/en
Publication of BR0300997A publication Critical patent/BR0300997A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"COMPOSTOS ARILIDENOTIAZOLIDINADIÈNICOS COM ATIVIDADE HIPOGLICêMICA". Os compostos inventados constituem novas séries de derivados tiazolidínicos, 5-arilideno-3-(4-metil-benzil)-tiazolidina-2,4-dionas (ATDZs) substituídos na posição 5 do anel tiazolidínico por grupamentos benzilideno substituídos ou indolideno; todos com usos farmacológicos e efeitos antidiabéticos. Constituem, assim, nova serie de agentes antidiabéticos agonistas do PPARg, hormónio nuclear receptor, com atividade hipoglicêmica e potencial uso terapêutico como drogas antidiabéticas.
BR0300997-1A 2003-04-10 2003-04-10 Compostos arilidenotiazolidinadiÈnicos com atividade hipoglicêmica BR0300997A (pt)

Priority Applications (2)

Application Number Priority Date Filing Date Title
BR0300997-1A BR0300997A (pt) 2003-04-10 2003-04-10 Compostos arilidenotiazolidinadiÈnicos com atividade hipoglicêmica
PCT/BR2004/000053 WO2004089276A2 (en) 2003-04-10 2004-04-08 Thiazolidinedione compounds with hypoglycemic properties

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BR0300997-1A BR0300997A (pt) 2003-04-10 2003-04-10 Compostos arilidenotiazolidinadiÈnicos com atividade hipoglicêmica

Publications (1)

Publication Number Publication Date
BR0300997A true BR0300997A (pt) 2005-05-10

Family

ID=33136631

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0300997-1A BR0300997A (pt) 2003-04-10 2003-04-10 Compostos arilidenotiazolidinadiÈnicos com atividade hipoglicêmica

Country Status (2)

Country Link
BR (1) BR0300997A (pt)
WO (1) WO2004089276A2 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9115122B2 (en) * 2012-12-20 2015-08-25 University Of Maryland, Baltimore Non-ATP dependent inhibitors of extracellular signal-regulated kinase (ERK)
EP4142795A4 (en) * 2020-04-27 2024-05-22 The Res Institute At Nationwide Childrens Hospital PPAR AGONISTS FOR THE TREATMENT OF KIDNEY DISEASE

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020052396A1 (en) * 2001-04-23 2002-05-02 Bailey Thomas R. Compounds, compositions and methods for treating or preventing viral infections and associated diseases

Also Published As

Publication number Publication date
WO2004089276A2 (en) 2004-10-21
WO2004089276A3 (en) 2005-01-27

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according art. 34 industrial property law
B25A Requested transfer of rights approved

Owner name: UNIVERSIDADE FEDERAL DE PERNAMBUCO - UFPE (BR/PE)

Free format text: TRANSFERIDO DE: CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTIFICO E TECNOLOGICO - CNPQ

B07D Technical examination (opinion) related to article 229 of industrial property law
B08E Application fees: requirement for complementation of annuity fee

Free format text: COMPLEMENTAR A RETRIBUICAO DA(S) 12A. ANUIDADE(S), DE ACORDO COM TABELA VIGENTE, REFERENTE A(S) GUIA(S) DE RECOLHIMENTO 22140385491-7 E COMPROVAR O RECOLHIMENTO DA 14A. ANUIDADE(S).

B08G Application fees: restoration
B07E Notice of approval relating to section 229 industrial property law
B06A Notification to applicant to reply to the report for non-patentability or inadequacy of the application according art. 36 industrial patent law
B09A Decision: intention to grant
B16A Patent or certificate of addition of invention granted
B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 16A ANUIDADE.

B24D Patent annual fee: restoration after fee payment