BR0212300A - Cyclic indole and heteroindole derivatives, their preparation and their use as medicines - Google Patents

Cyclic indole and heteroindole derivatives, their preparation and their use as medicines

Info

Publication number
BR0212300A
BR0212300A BR0212300-2A BR0212300A BR0212300A BR 0212300 A BR0212300 A BR 0212300A BR 0212300 A BR0212300 A BR 0212300A BR 0212300 A BR0212300 A BR 0212300A
Authority
BR
Brazil
Prior art keywords
preparation
derivatives
medicines
heteroindole
indole
Prior art date
Application number
BR0212300-2A
Other languages
Portuguese (pt)
Inventor
Heinz Weinberger
Thomas Beckers
Mathias Schmidt
Silke Baasner
Bernd Nickel
Original Assignee
Zentaris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10143079A external-priority patent/DE10143079A1/en
Application filed by Zentaris Gmbh filed Critical Zentaris Gmbh
Publication of BR0212300A publication Critical patent/BR0212300A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D515/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D515/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D515/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D515/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D515/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D515/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

"DERIVADOS DE INDOL E HETEROINDOL CìCLICOS, SUA PREPARAçãO E SEU USO COMO MEDICAMENTOS". A presente invenção refere-se a derivados de indol e heteroindol anelados, substituídos, da fórmula geral (I), a tautómeros, estereoisómeros, misturas e seus sais farmaceuticamente aceitáveis e à sua produção e uso como medicamentos, em particular como agentes antitumor em mamíferos, em particular seres humanos."CYCLIC INDOL AND HETEROINDOL DERIVATIVES, THEIR PREPARATION, AND THEIR USE AS MEDICINAL PRODUCTS". The present invention relates to substituted ringed indole and heteroindole derivatives of general formula (I), pharmaceutically acceptable tautomers, stereoisomers, mixtures and salts thereof and their production and use as medicaments, in particular as antitumor agents in mammals. , in particular humans.

BR0212300-2A 2001-09-03 2002-08-27 Cyclic indole and heteroindole derivatives, their preparation and their use as medicines BR0212300A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10143079A DE10143079A1 (en) 2001-09-03 2001-09-03 Cyclic indole and heteroindole derivatives, their production and use as medicines
PCT/EP2002/009539 WO2003020731A1 (en) 2001-09-03 2002-08-27 Cyclic indole and heteroindole derivatives, the production and use thereof as medicaments

Publications (1)

Publication Number Publication Date
BR0212300A true BR0212300A (en) 2004-10-13

Family

ID=32239891

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0212300-2A BR0212300A (en) 2001-09-03 2002-08-27 Cyclic indole and heteroindole derivatives, their preparation and their use as medicines

Country Status (15)

Country Link
EP (1) EP1423393A1 (en)
JP (1) JP2005508898A (en)
KR (1) KR20040029463A (en)
CN (1) CN1551885A (en)
AR (1) AR036776A1 (en)
BR (1) BR0212300A (en)
CA (1) CA2458399A1 (en)
HU (1) HUP0401446A3 (en)
IL (1) IL160441A0 (en)
MX (1) MXPA04002034A (en)
NO (1) NO20040831L (en)
NZ (1) NZ531642A (en)
PL (1) PL370210A1 (en)
RU (1) RU2004110412A (en)
ZA (1) ZA200401290B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111362891A (en) * 2020-04-01 2020-07-03 杭州福斯特药业有限公司 Production device and production method of acetyl tetrahydrofuran

Also Published As

Publication number Publication date
NZ531642A (en) 2005-01-28
RU2004110412A (en) 2005-03-20
MXPA04002034A (en) 2004-07-08
CA2458399A1 (en) 2003-03-13
IL160441A0 (en) 2004-07-25
NO20040831L (en) 2004-04-13
EP1423393A1 (en) 2004-06-02
KR20040029463A (en) 2004-04-06
ZA200401290B (en) 2004-03-23
CN1551885A (en) 2004-12-01
PL370210A1 (en) 2005-05-16
JP2005508898A (en) 2005-04-07
AR036776A1 (en) 2004-10-06
HUP0401446A2 (en) 2004-11-29
HUP0401446A3 (en) 2006-11-28

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A,6A E 7A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2029 DE 24/11/2009.