BR0211196A - Uso de derivados de fenila, fenol e benzoìla trifluoracetilalquila-substituìdos no tratamento e/ou na profilaxia da obesidade e suas doenças associadas e/ou decorrentes - Google Patents

Uso de derivados de fenila, fenol e benzoìla trifluoracetilalquila-substituìdos no tratamento e/ou na profilaxia da obesidade e suas doenças associadas e/ou decorrentes

Info

Publication number
BR0211196A
BR0211196A BR0211196-9A BR0211196A BR0211196A BR 0211196 A BR0211196 A BR 0211196A BR 0211196 A BR0211196 A BR 0211196A BR 0211196 A BR0211196 A BR 0211196A
Authority
BR
Brazil
Prior art keywords
phenol
benzoyl
obesity
substituted
treatment
Prior art date
Application number
BR0211196-9A
Other languages
English (en)
Inventor
Jochen Antel
Harald Waldeck
Andreas Potthoff
Sabine Irmer
Peter-Colin Gregory
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Publication of BR0211196A publication Critical patent/BR0211196A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Communicable Diseases (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"USO DE DERIVADOS DE FENILA, FENOL E BENZOìLA TRIFLUORACETILALQUILA-SUBSTITUìDOS NO TRATAMENTO E/OU NA PROFILAXIA DA OBESIDADE E SUAS DOENçAS ASSOCIADAS E/OU DECORRENTES". A presente invenção refere-se ao uso de novos e conhecidos compostos ativos inibidores de lipase da fórmula geral (I), em que A~ 1~, A~ 2~, R~ 2~ e Z possuem os significados dados na descrição, para o tratamento e/ou profilaxia de obesidade, bem como doenças associadas e/ou doenças decorrentes ligadas à obesidade.
BR0211196-9A 2001-07-18 2002-07-12 Uso de derivados de fenila, fenol e benzoìla trifluoracetilalquila-substituìdos no tratamento e/ou na profilaxia da obesidade e suas doenças associadas e/ou decorrentes BR0211196A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10135027A DE10135027A1 (de) 2001-07-18 2001-07-18 Verwendung Trifluoracetylalkyl-substituierter Phenyl-, Phenol- und Benzoylderivate in der Behandlung und/oder Prophylaxe von Obestias und deren Begleit- und/oder Folgeerkrankungen
PCT/EP2002/007782 WO2003007923A2 (de) 2001-07-18 2002-07-12 Verwendung von trifluoracetylalkyl-substituierte phenyl-, phenol- und benzoylderivate in der behandlung und/oder prophylaxe von obesitas und deren begleit- und/oder folgeerkrankungen

Publications (1)

Publication Number Publication Date
BR0211196A true BR0211196A (pt) 2004-10-26

Family

ID=7692273

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0211196-9A BR0211196A (pt) 2001-07-18 2002-07-12 Uso de derivados de fenila, fenol e benzoìla trifluoracetilalquila-substituìdos no tratamento e/ou na profilaxia da obesidade e suas doenças associadas e/ou decorrentes

Country Status (13)

Country Link
US (1) US6930207B2 (pt)
EP (1) EP1420771B9 (pt)
JP (1) JP4511172B2 (pt)
CN (1) CN1596106B (pt)
AT (1) ATE338542T1 (pt)
AU (1) AU2002328884B8 (pt)
BR (1) BR0211196A (pt)
CA (1) CA2455483C (pt)
DE (2) DE10135027A1 (pt)
HK (1) HK1073245A1 (pt)
MX (1) MXPA04000325A (pt)
PL (1) PL216996B1 (pt)
WO (1) WO2003007923A2 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA03011558A (es) * 2001-06-12 2004-03-26 Wellstat Therapeutics Corp Compuestos para el tratamiento de desordenes metabolicos.
PL377712A1 (pl) * 2003-02-13 2006-02-06 Wellstat Therapeutics Corporation Związki do leczenia zaburzeń metabolicznych
RU2403237C2 (ru) * 2004-05-14 2010-11-10 Эмисфире Текнолоджис, Инк. Составы и смеси для доставки активных агентов
KR100733516B1 (ko) 2005-09-29 2007-06-29 노키아 코포레이션 네트워크 기반 서비스들을 중개하는 네트워크 서비스 제공장치, 휴대용 전자 장치, 시스템 및 방법
US9102622B2 (en) 2006-07-28 2015-08-11 University Of Connecticut Fatty acid amide hydrolase inhibitors
AU2008210730A1 (en) * 2007-01-29 2008-08-07 Arete Therapeutics, Inc. Soluble epoxide hydrolase inhibitors for treatment of metabolic syndrome and related disorders
US20100048727A1 (en) * 2007-04-05 2010-02-25 Samuel David Perfluoroketone compounds and uses thereof

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3046300A (en) * 1960-10-21 1962-07-24 Merck & Co Inc alpha-trifluoromethyloxyphenylalanines
ZA714221B (en) * 1970-07-10 1972-03-29 Astra Ab Insecticides
US4051223A (en) * 1975-11-10 1977-09-27 General Mills Chemicals, Inc. Process for the recovery of magnesium
DE2918775A1 (de) * 1979-05-10 1980-11-20 Merck Patent Gmbh Diketone, verfahren zu ihrer herstellung und ihre verwendung als komponenten fluessigkristalliner dielektrika
US4408077A (en) * 1981-11-13 1983-10-04 Ayerst, Mckeena & Harrison, Inc. 6-(Lower alkoxy)-5-(trifluoromethyl)-1-naphthalenecarboxaldehydes
WO1987002367A2 (en) * 1985-10-18 1987-04-23 The Upjohn Company Cyclic hydrocarbons with an aminoalkyl sidechain
WO1988008002A1 (en) * 1987-04-16 1988-10-20 The Upjohn Company Cyclic hydrocarbons with an aminoalkyl sidechain
FR2614725B1 (fr) * 1987-04-28 1992-10-30 Rhone Poulenc Chimie Procede d'elimination de la radioactivite d'effluents par extraction liquide-liquide
FR2623798B1 (fr) * 1987-11-26 1990-05-04 Lucien Laboratoires Derives de trifluoromethyl-1 tetralines, leur preparation et leur application pour la synthese de composes presentant des proprietes therapeutiques
US4962024A (en) * 1988-08-11 1990-10-09 Becton, Dickinson And Company Signal enhancement in assay for an enzyme
FR2701259B1 (fr) * 1993-02-08 1995-03-24 Rhone Poulenc Agrochimie Procédé pour la préparation de dérivés phénylbenzamides fongicides agricoles.
ES2193609T3 (es) * 1993-11-30 2003-11-01 Searle & Co Pirazolil-bencenosulfonamidas sustituidas y su uso como inhibidores de la ciclooxigenasa ii.
DE19649093A1 (de) * 1996-11-27 1998-05-28 Bayer Ag Mikrobizide Mittel auf Basis von Thiophen-2-carbonsäure-Derivaten
AU730364B2 (en) * 1997-09-23 2001-03-08 Bristol-Myers Squibb Company Selective cPLA2 inhibitors
GB9900416D0 (en) * 1999-01-08 1999-02-24 Alizyme Therapeutics Ltd Inhibitors
GB9910378D0 (en) * 1999-05-05 1999-06-30 Smithkline Beecham Plc Novel compounds
CA2392931A1 (en) * 1999-12-03 2001-06-07 Pfizer Products Inc. Heterocyclo-alkylsulfonyl pyrazole derivatives as anti-inflammatory/analgesic agents
DE60001623T2 (de) * 1999-12-03 2003-12-18 Pfizer Prod Inc Sulfamoylheteroarylpyrazolverbindungen zur Verwendung als analgetisches/entzündungshemmendes Mittel
TR200001872A3 (tr) * 2000-06-26 2002-01-21 Fako Ilaclari A.S 4-[5-(4-Metilfenil-3-(triflorometil)-1H-pirazol-1-il] benzensulfonamit' in yeni kristal biçimi "Biçim I" ve bu ürünün üretilmesine iliskin yöntem.
US20020103192A1 (en) * 2000-10-26 2002-08-01 Curtin Michael L. Inhibitors of histone deacetylase

Also Published As

Publication number Publication date
WO2003007923A2 (de) 2003-01-30
CA2455483C (en) 2012-01-24
PL366933A1 (en) 2005-02-07
HK1073245A1 (en) 2005-09-30
MXPA04000325A (es) 2005-03-07
EP1420771B1 (de) 2006-09-06
AU2002328884B2 (en) 2008-02-07
PL216996B1 (pl) 2014-06-30
ATE338542T1 (de) 2006-09-15
US6930207B2 (en) 2005-08-16
EP1420771A2 (de) 2004-05-26
CN1596106A (zh) 2005-03-16
AU2002328884B8 (en) 2008-06-26
US20040214901A1 (en) 2004-10-28
CN1596106B (zh) 2011-05-11
DE50208081D1 (de) 2006-10-19
DE10135027A1 (de) 2003-02-06
JP4511172B2 (ja) 2010-07-28
CA2455483A1 (en) 2003-01-30
JP2005500329A (ja) 2005-01-06
WO2003007923A3 (de) 2004-01-08
EP1420771B9 (de) 2007-10-17

Similar Documents

Publication Publication Date Title
DK1206474T3 (da) Sulfonylphenylpyrazolforbindelser anvendelige som cox-2-inhibitorer
SE9800836D0 (sv) New Compounds
NO955256L (no) Fenylheterosykluser som syklooksygenase-2-inhibitorer
NO981628L (no) (Metylsulfonyl)fenyl-2-(5H)-furanoner som cox-2 inhibitorer
NO20055863L (no) W-karboksyarylsubstituerte difenylureaforbindelser som raf-kinaseinhibitorer
NO20045677L (no) Inhibitorer av JAK- og CDK2-proteinkinaser
NO20030381L (no) Bicyklopyrazoler som er aktive som kinaseinhibitorer, fremgangsmåte for deres fremstilling og farmasöytiske preparater som inneholder slikeforbindelser
NO20025601L (no) Arylmetylaminderivater for anvendelse som tryptaseinhibitorer
NO20061736L (no) Krystallform av epotilon B
SE0101675D0 (sv) Novel composition
TR199800759T2 (xx) Protein Kinaz C �nhibit�r�.
ECSP055525A (es) Inhibidores de cinasas de tirosina
NO20085373L (no) P38 inhibitorer, deres fremstilling og anvendelse
EA200501805A1 (ru) Фармацевтическая композиция, содержащая ингибитор фермента дипептидилпептидазы
TW200608979A (en) Pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis
ECSP055701A (es) Nuevos derivados de pirimidinamida y el uso de los mismos
ES2171723T3 (es) 3,4-diaril-2-hidroxi-2,5-dihidrofuranos como profarmacos de inhibidores de cox-2.
HK1073245A1 (en) Use of trifluoroacetyl alkyl-substituted phenyl derivatives, phenol derivatives, and benzoyl derivatives in the treatment and/or prophylaxis of obesity and accompanying diseases and/or secondary diseases
NO20065898L (no) 1-heterocyklyl-1,5-dihydro-pyrido[3,2-b]indol-2-oner
DK1307445T3 (da) Benzofuranderivater og deres anvendelse som antibakterielle midler
MXPA04005809A (es) Inhibidores de proteinas quinasas.
NO983511D0 (no) Difenylstilbener som pro-legemidler for COX-2-inhibitorer
ATE223376T1 (de) Bisarylcyclobutenderivate als cyclooxygenasehemmer
IL140768A0 (en) Chemotaxis-inhibiting protein of staphylococcus (chips) and its use
AU2001265876A1 (en) Novel use of pulmonary surfactant for the prophylaxis or early treatment of acute pulmonary diseases

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 14A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2385 DE 20-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]