BR0209552A - Dispositivo de modulação de imunidade para uso em animais - Google Patents

Dispositivo de modulação de imunidade para uso em animais

Info

Publication number
BR0209552A
BR0209552A BR0209552-1A BR0209552A BR0209552A BR 0209552 A BR0209552 A BR 0209552A BR 0209552 A BR0209552 A BR 0209552A BR 0209552 A BR0209552 A BR 0209552A
Authority
BR
Brazil
Prior art keywords
modulation device
animal immunity
immunity modulation
lymphokines
cytokines
Prior art date
Application number
BR0209552-1A
Other languages
English (en)
Other versions
BRPI0209552B1 (pt
Inventor
Kevor S Tenhuisen
Joel Rosenblatt
Ilya S Koyfmann
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of BR0209552A publication Critical patent/BR0209552A/pt
Publication of BRPI0209552B1 publication Critical patent/BRPI0209552B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"DISPOSITIVO DE MODULAçãO DE IMUNIDADE PARA USO EM ANIMAIS". A presente invenção refere-se a um dispositivo de modulação de imunidade que pode ser implantado que é útil para modulação de uma resposta imunológica nos mamíferos, compreendendo uma pluralidade de fibras, dentro de um revestimento poroso. O enchimento de fibra é carregado com antígenos únicos ou múltiplos, e opcionalmente um ou mais compostos biologicamente ativos tais como citocinas (por exemplo linfocinas, quimiocinas, etc.), fatores de fixação, genes, peptídios, proteínas, nucleotídeos, carboidratos ou células dependendo da aplicação.
BRPI0209552A 2001-05-11 2002-03-21 dispositivo de modulação de imunidade e método para fabrica-lo BRPI0209552B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29054201P 2001-05-11 2001-05-11
PCT/US2002/008872 WO2002092054A2 (en) 2001-05-11 2002-03-21 Immune modulation device for use in animals

Publications (2)

Publication Number Publication Date
BR0209552A true BR0209552A (pt) 2004-05-04
BRPI0209552B1 BRPI0209552B1 (pt) 2016-05-10

Family

ID=23116478

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0209552A BRPI0209552B1 (pt) 2001-05-11 2002-03-21 dispositivo de modulação de imunidade e método para fabrica-lo

Country Status (11)

Country Link
US (3) US6958158B2 (pt)
EP (1) EP1387670B1 (pt)
JP (1) JP4866535B2 (pt)
KR (1) KR20030096381A (pt)
CN (1) CN1289063C (pt)
AT (1) ATE411001T1 (pt)
AU (1) AU2002305079B8 (pt)
BR (1) BRPI0209552B1 (pt)
CA (1) CA2447030C (pt)
DE (1) DE60229375D1 (pt)
WO (1) WO2002092054A2 (pt)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7399751B2 (en) * 1999-11-04 2008-07-15 Sertoli Technologies, Inc. Production of a biological factor and creation of an immunologically privileged environment using genetically altered Sertoli cells
US20030118630A1 (en) * 2001-12-07 2003-06-26 Anthony Cerami Immune modulation device for use in animals
DE10203644A1 (de) * 2002-01-30 2003-08-07 Fraunhofer Ges Forschung Kryokonservierung an textilen Geweben
US20040156878A1 (en) * 2003-02-11 2004-08-12 Alireza Rezania Implantable medical device seeded with mammalian cells and methods of treatment
US6974862B2 (en) * 2003-06-20 2005-12-13 Kensey Nash Corporation High density fibrous polymers suitable for implant
US20050118145A1 (en) * 2003-07-03 2005-06-02 Jannette Dufour Compositions containing sertoli cells and myoid cells and use thereof in cellular transplants
US20050260258A1 (en) * 2003-12-18 2005-11-24 The Texas A&M University System Use of vitelline protein B as a microencapsulating additive
US8067237B2 (en) 2005-12-13 2011-11-29 President And Fellows Of Harvard College Scaffolds for cell transplantation
US20100055154A1 (en) * 2006-07-24 2010-03-04 I-Chien Liao Coaxial electrospun fibers and structures and methods of forming the same
CA2658951A1 (en) * 2006-07-28 2008-01-31 Sertocell Biotechnology (Us) Corp. Adult sertoli cells and uses thereof
CN101522232B (zh) * 2006-09-29 2012-03-21 东丽株式会社 细胞吸附柱
US10328133B2 (en) 2008-02-13 2019-06-25 President And Fellows Of Harvard College Continuous cell programming devices
EP2276420B1 (en) 2008-04-04 2021-10-06 Journey1, Inc. Device to treat an eye having an epithelium with a defect
US9498385B2 (en) 2009-10-23 2016-11-22 Nexisvision, Inc. Conformable therapeutic shield for vision and pain
NO2490635T3 (pt) 2009-10-23 2018-02-03
EP2515877B1 (en) 2009-12-21 2016-08-10 Janssen Sciences Ireland UC Degradable removable implant for the sustained release of an active compound
CA2793959C (en) 2010-03-25 2019-06-04 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
US20110270168A1 (en) * 2010-05-03 2011-11-03 Izhar Halahmi Releasing device for administering a bio-active agent
WO2012012162A2 (en) * 2010-06-30 2012-01-26 Surmodics Pharmaceuticals, Inc. Core-sheath implant device having an inner core lobe
DK2624873T3 (da) 2010-10-06 2020-03-02 Harvard College Injicerbare, pore-dannende hydrogeler til materiale-baserede celleterapier
WO2014210186A2 (en) 2013-06-26 2014-12-31 Nexisvision, Inc. Contact lenses for refractive correction
US12044905B2 (en) 2011-04-28 2024-07-23 Journey1 Inc Contact lenses for refractive correction
KR101275163B1 (ko) * 2011-05-26 2013-06-17 한국생산기술연구원 다공질의 3차원 지지체 및 그의 제조방법
EP2691530B1 (en) 2011-06-10 2018-03-07 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
US20130189754A1 (en) 2011-09-12 2013-07-25 International Aids Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
US9402894B2 (en) 2011-10-27 2016-08-02 International Aids Vaccine Initiative Viral particles derived from an enveloped virus
CA2870309C (en) 2012-04-16 2024-02-20 President And Fellows Of Harvard College Mesoporous silica compositions for modulating immune responses
ES2631608T3 (es) 2012-06-27 2017-09-01 International Aids Vaccine Initiative Variante de la glicoproteína Env del VIH-1
US20150065381A1 (en) 2013-09-05 2015-03-05 International Aids Vaccine Initiative Methods of identifying novel hiv-1 immunogens
EP2873423B1 (en) 2013-10-07 2017-05-31 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
CN107073090A (zh) 2014-04-30 2017-08-18 哈佛学院董事会 结合的疫苗装置和杀死癌细胞的方法
CA3012602A1 (en) 2015-01-30 2016-08-04 President And Fellows Of Harvard College Peritumoral and intratumoral materials for cancer therapy
US10174292B2 (en) 2015-03-20 2019-01-08 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
EP3072901A1 (en) 2015-03-23 2016-09-28 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
EP3280464A4 (en) 2015-04-10 2018-09-26 President and Fellows of Harvard College Immune cell trapping devices and methods for making and using the same
WO2017136837A1 (en) 2016-02-06 2017-08-10 President And Fellows Of Harvard College Recapitulating the hematopoietic niche to reconstitute immunity
CN115305229A (zh) 2016-07-13 2022-11-08 哈佛学院院长等 抗原呈递细胞模拟支架及其制备和使用方法
CN111001226B (zh) * 2018-10-07 2023-02-10 嘉兴启净涂装科技有限公司 一种在管状物中填充纤维材料的方法
WO2020170961A1 (ja) * 2019-02-22 2020-08-27 東レ株式会社 神経再生誘導チューブ
CN111202836A (zh) * 2020-02-07 2020-05-29 嫦娥创新(武汉)生物科技有限公司 鲟鱼蛋白肽在制备免疫调节制剂中的应用
WO2021185373A1 (zh) * 2020-03-20 2021-09-23 苏州医本生命科技有限公司 载药用微粒、载药微粒、蓄粒管及其植入系统

Family Cites Families (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US118630A (en) * 1871-08-29 Improvement in ice-pitchers
US3887699A (en) 1969-03-24 1975-06-03 Seymour Yolles Biodegradable polymeric article for dispensing drugs
US4052550A (en) 1973-06-06 1977-10-04 Rhone-Poulenc-Textile Poly(vinylidene fluoride) yarns and fibers
US3937223A (en) * 1974-04-19 1976-02-10 American Cyanamid Company Compacted surgical hemostatic felt
US4052988A (en) 1976-01-12 1977-10-11 Ethicon, Inc. Synthetic absorbable surgical devices of poly-dioxanone
US4164560A (en) 1977-01-05 1979-08-14 Folkman Moses J Systems for the controlled release of macromolecules
US4141087A (en) 1977-01-19 1979-02-27 Ethicon, Inc. Isomorphic copolyoxalates and sutures thereof
US4208511A (en) 1977-01-19 1980-06-17 Ethicon, Inc. Isomorphic copolyoxalates and sutures thereof
US4105034A (en) 1977-06-10 1978-08-08 Ethicon, Inc. Poly(alkylene oxalate) absorbable coating for sutures
US4140678A (en) 1977-06-13 1979-02-20 Ethicon, Inc. Synthetic absorbable surgical devices of poly(alkylene oxalates)
US4205399A (en) 1977-06-13 1980-06-03 Ethicon, Inc. Synthetic absorbable surgical devices of poly(alkylene oxalates)
US4130639A (en) 1977-09-28 1978-12-19 Ethicon, Inc. Absorbable pharmaceutical compositions based on isomorphic copolyoxalates
US4224946A (en) 1978-08-14 1980-09-30 American Cyanamid Company Surgical sutures derived from segmented polyether-ester block copolymers
US5102419A (en) 1978-12-08 1992-04-07 Ethicon, Inc. Elastomeric surgical sutures comprising segmented copolyether/esters
US5147382A (en) 1978-12-08 1992-09-15 Ethicon, Inc. Elastomeric surgical sutures comprising segmented copolyether/esters
US4314561A (en) 1979-01-29 1982-02-09 American Cyanamid Company Surgical suture derived from segmented polyether-ester block copolymers
US4919929A (en) 1984-02-01 1990-04-24 Stolle Research & Development Corporation Mammal immunization
US4700704A (en) 1982-10-01 1987-10-20 Ethicon, Inc. Surgical articles of copolymers of glycolide and ε-caprolactone and methods of producing the same
US4605730A (en) 1982-10-01 1986-08-12 Ethicon, Inc. Surgical articles of copolymers of glycolide and ε-caprolactone and methods of producing the same
US4520822A (en) 1982-10-04 1985-06-04 Ethicon, Inc. Ethylene-propylene copolymer sutures
US4689220A (en) * 1984-02-16 1987-08-25 Unigene Laboratories, Inc. Immunization by immunogenic implant
US4557264A (en) 1984-04-09 1985-12-10 Ethicon Inc. Surgical filament from polypropylene blended with polyethylene
US4564013A (en) 1984-05-24 1986-01-14 Ethicon, Inc. Surgical filaments from vinylidene fluoride copolymers
US4732155A (en) 1985-08-27 1988-03-22 The Children's Medical Center Corporation Implantable chemoattractant system
EP0287899A3 (en) 1987-04-23 1989-12-27 American Cyanamid Company Surgical closure device
DE3785033T2 (de) 1987-07-21 1993-10-07 Stolle Res & Dev Verfahren zum Erhalten von immunregulierenden Faktoren mittels Säugetierimmunisierung.
DE19975054I2 (de) 1987-08-08 2000-04-13 Akzo Nobel Nv Kontrazeptives Implantat
CA1329100C (en) * 1988-05-16 1994-05-03 Arnold Kastner Portable manually operable cigarette making machine
US5133739A (en) 1990-02-06 1992-07-28 Ethicon, Inc. Segmented copolymers of ε-caprolactone and glycolide
EP0448840A3 (en) 1990-02-26 1993-03-10 American Cyanamid Company Bicomponent or blended wound closure device
WO1991019464A1 (en) * 1990-06-15 1991-12-26 E.I. Du Pont De Nemours And Company Crimped fiber composite articles and processes for the preparation thereof
DE69121587T3 (de) * 1990-12-06 2000-05-31 W.L. Gore & Associates, Newark Implantierbare bioresorbierbare artikel
WO1993017662A1 (en) 1992-03-02 1993-09-16 Daratech Pty. Ltd. Improved implants
JPH05312065A (ja) * 1992-05-06 1993-11-22 Nippondenso Co Ltd 内燃機関のバイパス空気量制御装置
US5269807A (en) 1992-08-27 1993-12-14 United States Surgical Corporation Suture fabricated from syndiotactic polypropylene
CA2114290C (en) 1993-01-27 2006-01-10 Nagabushanam Totakura Post-surgical anti-adhesion device
AU7568094A (en) * 1993-08-12 1995-03-14 Cytotherapeutics, Inc. Improved compositions and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules
US5542594A (en) 1993-10-06 1996-08-06 United States Surgical Corporation Surgical stapling apparatus with biocompatible surgical fabric
US5431679A (en) 1994-03-10 1995-07-11 United States Surgical Corporation Absorbable block copolymers and surgical articles fabricated therefrom
US5442032A (en) 1994-03-15 1995-08-15 Ethicon, Inc. Copolymers of 1,4-dioxepan-2-one and 1,5,8,12-tetraoxacyclotetradecane-7-14-dione
ATE212230T1 (de) 1994-04-13 2002-02-15 Res Corp Technologies Inc Methoden zur krankheitsbehandlung unter verwendung von sertoli-zellen und allotransplantat oder xenotransplantat
TW369414B (en) * 1994-09-30 1999-09-11 Yamanouchi Pharma Co Ltd Bone formation transplant
US5648088A (en) 1995-03-06 1997-07-15 Ethicon, Inc. Blends of absorbable polyoxaesters containing amines and/or amide groups
US5595751A (en) 1995-03-06 1997-01-21 Ethicon, Inc. Absorbable polyoxaesters containing amines and/or amido groups
US5607687A (en) 1995-03-06 1997-03-04 Ethicon, Inc. Polymer blends containing absorbable polyoxaesters
US5597579A (en) 1995-03-06 1997-01-28 Ethicon, Inc. Blends of absorbable polyoxaamides
US5859150A (en) 1995-03-06 1999-01-12 Ethicon, Inc. Prepolymers of absorbable polyoxaesters
US5698213A (en) 1995-03-06 1997-12-16 Ethicon, Inc. Hydrogels of absorbable polyoxaesters
US5618552A (en) 1995-03-06 1997-04-08 Ethicon, Inc. Absorbable polyoxaesters
US5464929A (en) 1995-03-06 1995-11-07 Ethicon, Inc. Absorbable polyoxaesters
US5696213A (en) * 1995-04-21 1997-12-09 Exxon Chemical Patents Inc. Ethylene-α-olefin-diolefin elastomers solution polymerization process
US5700533A (en) 1995-10-05 1997-12-23 You; Chin-San Fiber Braid Material
ATE244024T1 (de) * 1996-02-05 2003-07-15 Asahi Medical Co Sterilisationsschutzmittel und verfahren zur sterilisation
US5703200A (en) 1996-03-15 1997-12-30 Ethicon, Inc. Absorbable copolymers and blends of 6,6-dialkyl-1,4-dioxepan-2-one and its cyclic dimer
US5796584A (en) 1996-04-30 1998-08-18 Telefonaktiebolaget Lm Ericsson Bridge for power transistors with improved cooling
IL118376A0 (en) * 1996-05-22 1996-09-12 Univ Ben Gurion Polysaccharide sponges for cell culture and transplantation
US6200589B1 (en) * 1996-09-13 2001-03-13 The University Of Akron Biological implants of semipermeable amphiphilic membranes
US5854383A (en) 1997-10-06 1998-12-29 Ethicon, Inc. Aliphatic polyesters of trimethylene carbonate epsilon-caprolactone and glycolide
WO1999044583A2 (en) * 1998-03-02 1999-09-10 Applied Vaccine Technologies Corp. Methods and devices for modulating the immune response
US6303136B1 (en) * 1998-04-13 2001-10-16 Neurotech S.A. Cells or tissue attached to a non-degradable filamentous matrix encapsulated by a semi-permeable membrane
US6551355B1 (en) * 1998-08-14 2003-04-22 Cambridge Scientific, Inc. Tissue transplant coated with biocompatible biodegradable polymer
US20030118630A1 (en) 2001-12-07 2003-06-26 Anthony Cerami Immune modulation device for use in animals

Also Published As

Publication number Publication date
EP1387670B1 (en) 2008-10-15
JP2004532243A (ja) 2004-10-21
US20040086517A1 (en) 2004-05-06
US6958158B2 (en) 2005-10-25
CN1527697A (zh) 2004-09-08
US7094419B2 (en) 2006-08-22
ATE411001T1 (de) 2008-10-15
WO2002092054A3 (en) 2003-03-27
CN1289063C (zh) 2006-12-13
JP4866535B2 (ja) 2012-02-01
WO2002092054A2 (en) 2002-11-21
KR20030096381A (ko) 2003-12-24
BRPI0209552B1 (pt) 2016-05-10
US20030068812A1 (en) 2003-04-10
US20050106129A1 (en) 2005-05-19
AU2002305079B2 (en) 2006-05-11
EP1387670A2 (en) 2004-02-11
DE60229375D1 (de) 2008-11-27
CA2447030C (en) 2010-07-13
CA2447030A1 (en) 2002-11-21
AU2002305079B8 (en) 2006-05-25

Similar Documents

Publication Publication Date Title
BR0209552A (pt) Dispositivo de modulação de imunidade para uso em animais
WO2003020161A3 (en) Immune modulation device for use in animals
DE58907079D1 (de) (Meth)acryloxygruppen enthaltende flüssigkristalline Polyorganosiloxane.
DK1511845T3 (da) Immunstimulatoriske oligonukleotider og anvendelser deraf
DE69734882D1 (de) Dna immunisierung gegen chlamydia infektion
CY1108013T1 (el) Dna εμβολια για τους ιππους που περιεχουν ανοσοενισχυτικους παραγοντες με πολυμερη του ακρυλικου ή μεθακρυλικου οξεος ή του εμα(r)
DE69822495D1 (de) Nadellose injektionsstelle
ES2180538T3 (es) Suministro dirigido de vector virico a celulas de mamiferos.
FR2741806B1 (fr) Vaccin vivant recombinant a base d'herpesvirus felin de type 1, notamment contre la peritonite infectieuse feline
DE19982971T1 (de) Bewahren von Schleifen-Fairneß mit dynamischem Halbduplexbetrieb
BR0207775A (pt) Lipossomos anfotéricos métodos para carregamento dos mesmos com ingredientes ativos e sua utilização
CO5590973A2 (es) Acido nucleico de adenovirus de simio y secuiencias de aminoacidos, vectores que contienen los mismos y metodos de uso
DE69942072D1 (de) Von der Telomerase abgeleitete antigene Peptide
ID18351A (id) Vaksin hidup rekombinan avian, yang sebagai vektor menggunakan virus laringotracheitis menular avian
PT942901E (pt) Iminas ciclicas utilizadas como pesticidas
DE69836557D1 (de) Rekombinanten des infektiösen vogel-herpesvirus und rekombinante impfstoffe, die unter dessen verwendung hergestellt wurden
NO992916D0 (no) Fosfodiesterase 8A
DE68907419D1 (de) Stabile, waessrige faellungskieselsaeuresuspension.
ES2194455T3 (es) Hendidura de derivacion longitudinal centrada alimentada mediante diafragma resonante de reborde desplazado.
TR199802573A3 (tr) Bir etken madde içeren çökelmis silisler.
ATE309356T1 (de) Konstruierte fluoreszenzproteine mit langen wellenlängen
DE69804774D1 (de) Neutral-gealterte, hydrophobische organosilikat-modifizierte kieselsäuregele
DE69812304D1 (de) Härtbare Silikonelastomere mit niedrigem Druckverformungsrest
DE60106222D1 (de) Herpesviren für die modulation einer immunantwort
EA200300417A1 (ru) Пестицидная композиция

Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Free format text: JOHNSON & JOHNSON (US)

B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DA INT.CL: A61K 9/00, A61K 39/39

Ipc: A61K 9/00 (2011.01), A61K 39/39 (2011.01), A61P 37

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]

Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI.

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]

Free format text: EXIGENCIAS FORMAIS, FALTA DE CLAREZA DAS REIVINDICACOES (ART.25)

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 10/05/2016, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 20A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2662 DE 11-01-2022 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.