BR0208532A - Vacina contra leishmania - Google Patents

Vacina contra leishmania

Info

Publication number
BR0208532A
BR0208532A BR0208532-1A BR0208532A BR0208532A BR 0208532 A BR0208532 A BR 0208532A BR 0208532 A BR0208532 A BR 0208532A BR 0208532 A BR0208532 A BR 0208532A
Authority
BR
Brazil
Prior art keywords
present
dna vaccine
vaccine
leishmania
vector encoding
Prior art date
Application number
BR0208532-1A
Other languages
English (en)
Inventor
Greg Matlashewski
Original Assignee
Univ Mcgill
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Mcgill filed Critical Univ Mcgill
Publication of BR0208532A publication Critical patent/BR0208532A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens
    • A61K39/008—Leishmania antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

"VACINA CONTRA LEISHMANIA". A presente invenção proporciona uma vacina de DNA que elícita uma resposta imune no hospedeiro em que a mesma é administrada, contra infecção por Leishmania. A presente invenção também se refere a processos para administrar a vacina de DNA. Em uma concretização, a vacina de DNA contém um vetor codificando o gene A2 da Leishmania donovani em um meio fisiologicamente aceitável. A presente invenção contém adicionalmente um adjuvante biológico que inclui um vetor codificando um gene selecionado, o gene selecionado sendo capaz de mediar a degradação da proteina celular p53.
BR0208532-1A 2001-03-29 2002-03-27 Vacina contra leishmania BR0208532A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27942301P 2001-03-29 2001-03-29
PCT/CA2002/000437 WO2002078735A2 (en) 2001-03-29 2002-03-27 Leishmania vaccines

Publications (1)

Publication Number Publication Date
BR0208532A true BR0208532A (pt) 2005-01-18

Family

ID=23068901

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0208532-1A BR0208532A (pt) 2001-03-29 2002-03-27 Vacina contra leishmania

Country Status (7)

Country Link
US (1) US20040170636A1 (pt)
EP (1) EP1372705A2 (pt)
BR (1) BR0208532A (pt)
CA (1) CA2442298A1 (pt)
IL (1) IL158124A0 (pt)
MX (1) MXPA03008832A (pt)
WO (1) WO2002078735A2 (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008009088A2 (en) 2006-07-21 2008-01-24 Universidade Federal De Minas Gerais Vaccine composition and immunization method

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10314412A1 (de) * 2003-03-28 2004-10-14 Genovac Ag Genetische Immunisierung mit multiplen Expressionskonstrukten zur Herstellung von monoklonalen Antikörpern
US8968749B2 (en) 2006-07-21 2015-03-03 Universidade Federal De Minas Gerais—Ufmg Vaccine composition and immunization method
BRPI0800485B8 (pt) * 2008-01-17 2021-05-25 Univ Minas Gerais vetores virais recombinantes, composição vacinal para leishmaniose e método de vacinação para leishmaniose
EP2300051B1 (en) * 2008-05-21 2014-11-12 Infectious Disease Research Institute Recombinant polyprotein vaccines for the treatment and diagnosis of leishmaniasis
US8410258B2 (en) 2008-05-21 2013-04-02 Infections Disease Research Institute Recombinant polyprotein vaccines for the treatment and diagnosis of leishmaniasis
US11833197B2 (en) * 2018-02-13 2023-12-05 University Of Iowa Research Foundation Immunotherapy of leishmaniasis
US10898460B1 (en) 2018-07-20 2021-01-26 University Of South Florida Leishmania inhibitors
ES2795149B2 (es) 2020-06-08 2022-07-04 Univ Madrid Complutense Quimera sintetica multiepitopica como vacuna y tratamiento frente a leishmaniosis en mamiferos

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE236252T1 (de) * 1993-09-03 2003-04-15 Univ Mcgill Differentiell exprimierte leishmania gene und proteinen
NZ512730A (en) * 1998-12-04 2003-12-19 Univ Manitoba A immunization procedure against chlamydia infection using an attenuated bacteria comprsing a plasmid with a major outer membrane protein (MOMP) from chlamydial

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008009088A2 (en) 2006-07-21 2008-01-24 Universidade Federal De Minas Gerais Vaccine composition and immunization method

Also Published As

Publication number Publication date
WO2002078735A3 (en) 2003-04-10
EP1372705A2 (en) 2004-01-02
IL158124A0 (en) 2004-03-28
US20040170636A1 (en) 2004-09-02
CA2442298A1 (en) 2002-10-10
MXPA03008832A (es) 2004-05-05
WO2002078735A2 (en) 2002-10-10

Similar Documents

Publication Publication Date Title
CY1110547T1 (el) Συμπυκνωμενα πρωτεϊνικα σκευασματα μειωμενου ιξωδους
BR9915988A (pt) Vacina para peptidase c5a estreptocócica
CY1107950T1 (el) Νεϊσσεριακες συνθεσεις εμβολιου και μεθοδοι
EP1220925B8 (en) Chlamydia antigens and corresponding dna fragments and uses thereof
NO20015073D0 (no) Vaksiner
AR032912A1 (es) Formulacion farmaceutica
BR9911163A (pt) Formulação de vacina, formulação farmacêutica, vìrus atenuado de influenza, processos para vacinar um indivìduo, para prevenir uma doença infecciosa em um indivìduo, e, para tratar ou prevenir tumores em um indivìduo
BRPI0416796A (pt) compostos orgánicos
DE60044146D1 (de) D ihre verwendungen
BR0208532A (pt) Vacina contra leishmania
NO20062948L (no) Promotere for ekspresjon i modifisert vaccinia-virus Ankara
AR024771A1 (es) Genes y vacunas efectivas contra la calicivirosis felina, en particular vacunas recombinantes
ES2146214T3 (es) Vacunas para actinobacillus pleuropneumoniae.
BRPI0409865A (pt) injeção intravenosa de ativadores de plasminogênio não neurotóxicos para o tratamento do ataque de apoplexia
BR0207018A (pt) Leptina modificada com imunogenicidade reduzida
ATE310747T1 (de) Impfstoff gegen geflügelkokzidose
DE69521007D1 (de) Impfstoff gegen Geflügelkokzidose
BR0211991A (pt) HormÈnio do crescimento humano modificado
FR2809960B1 (fr) Composition adjuvante de la reponse immunitaire comprenant la proteine fha ou un fragment de la proteine fha sous forme libre, et composition immunogene ou vaccinale contenant une telle composition adjuvante
ATE493146T1 (de) Igf-1 als impfstoffhilfsmittel für katzen, insbesondere gegen feline retroviren
ATE335507T1 (de) Impfstoff gegen infektionen mit onkoviren, wie dem felinen leukosevirus der katze
YU99603A (sh) Geni koji su povezani sa virulencijom parazita laišmanije
AR022662A1 (es) Acidos nucleicos y proteinas del gen mhp3 de mycoplasma hyopneumoniae y sus usos
FR2724385B1 (fr) Vaccin de la peritonite infectieuse feline.
MY191101A (en) Protein from photobacterium damselae and use thereof

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]