BR0206680A - Cell or tissue culture reactors, for implant preparation, use, and implant manufacturing process - Google Patents

Cell or tissue culture reactors, for implant preparation, use, and implant manufacturing process

Info

Publication number
BR0206680A
BR0206680A BR0206680-7A BR0206680A BR0206680A BR 0206680 A BR0206680 A BR 0206680A BR 0206680 A BR0206680 A BR 0206680A BR 0206680 A BR0206680 A BR 0206680A
Authority
BR
Brazil
Prior art keywords
implant
culture
reactor
cell
tissues
Prior art date
Application number
BR0206680-7A
Other languages
Portuguese (pt)
Inventor
Philippe Gault
Original Assignee
Natural Implant
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Natural Implant filed Critical Natural Implant
Publication of BR0206680A publication Critical patent/BR0206680A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04—Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/20—Material Coatings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0003—Not used, see subgroups
    • A61C8/0004—Consolidating natural teeth
    • A61C8/0006—Periodontal tissue or bone regeneration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0087—Means for sterile storage or manipulation of dental implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Mechanical Engineering (AREA)
  • Cell Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

"REATORES PARA A CULTURA CELULAR OU TISSULAR, PARA A PREPARAçãO DE UM IMPLANTE,. UTILIZAçãO DOS MESMOS, E, PROCESSO DE FABRICAçãO DE UM IMPLANTE". A invenção refere-se a um reator de cultura celular e tissular, particularmente adaptado à cultura de células ou tecidos de estrutura em camada fina, e compreende meios permitindo assegurar uma estimulação fisiológica e uma alimentação em meio de cultura adaptado à espessura reduzida da cultura. O reator pode servir à preparação de um implante e comporta, igualmente, meios permitindo assegurar uma estimulação mecânica dos tecidos ou células e uma alimentação em meio de cultura adaptada aos tecidos de estrutura. O reator comporta, igualmente, de modo vantajoso, meios ou uma forma permitindo facilitar a introdução do tecido ou da parte sólida de um implante na câmara de cultura, e por exemplo uma parede ou um elemento deformável elasticamente. O reator pode, por outro lado, comportar meios de regulagem da temperatura. O reator é utilizável para a cultura de diferentes tipos celulares e a preparação de implantes de formas, composições e aplicações variadas."REACTORS FOR CELL OR CISSULAR CULTURE, FOR PREPARATION OF AN IMPLANT, USE OF THE SAME AND, PROCESS FOR MANUFACTURING AN IMPLANT". The invention relates to a cell and tissue culture reactor, particularly adapted to the culture of thin-layered cells or tissues, and comprises means for ensuring physiological stimulation and feeding in culture medium adapted to the reduced thickness of the culture. The reactor can be used to prepare an implant and also includes means for ensuring mechanical stimulation of tissues or cells and feeding in culture medium adapted to the structural tissues. The reactor also advantageously comprises means or a shape which facilitates the introduction of tissue or solid part of an implant into the culture chamber, and for example a resiliently deformable wall or element. The reactor may, on the other hand, include temperature regulating means. The reactor is usable for culturing different cell types and preparing implants of various shapes, compositions and applications.

BR0206680-7A 2001-03-09 2002-03-08 Cell or tissue culture reactors, for implant preparation, use, and implant manufacturing process BR0206680A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0103242A FR2821853B1 (en) 2001-03-09 2001-03-09 BIOREACTOR FOR THIN FILM CULTIVE TISSUE AND USES
PCT/FR2002/000834 WO2002072750A1 (en) 2001-03-09 2002-03-08 Bio-reactor for tissue cultivated in the form of a thin layer and uses thereof

Publications (1)

Publication Number Publication Date
BR0206680A true BR0206680A (en) 2004-02-10

Family

ID=8860937

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0206680-7A BR0206680A (en) 2001-03-09 2002-03-08 Cell or tissue culture reactors, for implant preparation, use, and implant manufacturing process

Country Status (9)

Country Link
US (1) US7163825B2 (en)
EP (1) EP1366145A1 (en)
JP (1) JP2004528832A (en)
CN (1) CN100408670C (en)
BR (1) BR0206680A (en)
CA (1) CA2439731A1 (en)
FR (1) FR2821853B1 (en)
PL (1) PL362575A1 (en)
WO (1) WO2002072750A1 (en)

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DE10222896A1 (en) * 2002-05-23 2003-12-11 Biotissue Technologies Ag Process for the production of a three-dimensional and flat tissue graft
DE102004012010A1 (en) * 2004-03-10 2005-09-29 Fachhochschule Gießen-Friedberg Invention concerning bioreactors and bioreactor systems
US20080274545A1 (en) * 2005-03-02 2008-11-06 Government Of The Us, As Represented By The Secret Bioreactor Chamber Apparatus, and Method and System for Fabricating and Mechanically Stimulating Natural and Engineered Tissues
GB0520021D0 (en) * 2005-10-01 2005-11-09 Univ Liverpool A reactor
US8951784B2 (en) * 2005-12-14 2015-02-10 Sepragen Corporation Cell culture bioreactor
US7981668B2 (en) * 2006-01-18 2011-07-19 Kci Licensing Inc. System and method for applying reduced pressure to cell culture
ATE531792T1 (en) * 2006-03-30 2011-11-15 Mark Clarke THREE-DIMENSIONAL MINERALIZED BONE CONSTRUCTS
KR100799988B1 (en) 2006-11-30 2008-01-31 연세대학교 산학협력단 The bio-reactor which exerts various mechanical stimula for nurturing of stem cell and the method of nuturing of stem cell which uses it
EP1953220A1 (en) * 2007-02-01 2008-08-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for applying mechanical loading to cells and apparatus for implementing such method
EP2288688A2 (en) * 2008-03-25 2011-03-02 Novatissue Gmbh Perfusable bioreactor for the production of human or animal tissues
CN101676382B (en) * 2008-09-18 2013-03-27 中国人民解放军第三军医大学 Biomimetic tissue culture room
DE102008058782A1 (en) * 2008-11-24 2010-05-27 Rheinische Friedrich-Wilhelms-Universität Bonn Device for physiological, dynamic in vitro cell dilatation
JP5476562B2 (en) * 2009-03-17 2014-04-23 公益財団法人ヒューマンサイエンス振興財団 Cell differentiation device, cell differentiation method, and odontoblast
US8492135B2 (en) * 2009-04-03 2013-07-23 Tissue Growth Technologies Corporation Deformable transportable bioreactor chamber
KR101131303B1 (en) 2009-06-08 2012-03-30 한국과학기술원 Device and system for culturing cells and method of culturing cells using the same
EP2500410A1 (en) * 2011-03-18 2012-09-19 Ludwig-Maximilians-Universität München Bioreactor with mechanical and electrical stimulation means
US9606035B2 (en) 2011-12-21 2017-03-28 Ta Instruments-Waters Llc System for mechanical stimulation and characterization of biologic samples
US8685241B1 (en) 2011-12-21 2014-04-01 Sepragen Corporation Axial and radial flow columns with inflatable seals to facilitate packing and unpacking
DE102012101078A1 (en) * 2012-02-09 2013-10-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Stimulation cell and method for in vitro stimulation of cells or tissues
CN102727317B (en) * 2012-07-17 2015-05-20 四川大学 Oral implant device
WO2017180762A1 (en) * 2016-04-12 2017-10-19 Thrive Bioscience, Inc. Vessel for culturing cells
CN115044471A (en) 2016-08-27 2022-09-13 三维生物科技有限公司 Bioreactor
CN110129253A (en) * 2016-09-14 2019-08-16 四川蓝光英诺生物科技股份有限公司 Artificial organ precursor and the method for preparing it
FR3078712B1 (en) * 2018-03-12 2020-03-06 Centre D'etude Des Cellules Souches (Cecs) PROCESS AND DEVICE FOR THE PREPARATION OF AN IMPLANT FROM A STEM CELL CULTURE
JP2021522982A (en) * 2018-05-15 2021-09-02 エファレント ラブス，インコーポレイテッド Embeddable devices and usage
CN109444344B (en) * 2018-12-17 2020-06-23 中国矿业大学 Experimental device and method for micro-motion stimulation of bone growth of artificial joint biological fixation interface
US20220195368A1 (en) * 2020-12-21 2022-06-23 Upside Foods, Inc. Fluid conduit with radial expansion of fluid flow

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JPH037575A (en) * 1989-03-30 1991-01-14 Shimadzu Corp Apparatus for cell culture
US5217899A (en) * 1990-08-24 1993-06-08 The General Hospital Corporation Cell stretching apparatus
US6228635B1 (en) * 1995-06-07 2001-05-08 Aastrom Bioscience, Inc. Portable cell growth cassette for use in maintaining and growing biological cells
CN2236493Y (en) * 1995-11-07 1996-10-02 许晓增 Biologic reactor for cell culture
WO1997026023A1 (en) * 1996-01-19 1997-07-24 Eth, Eidgenössische Technische Hochschule Zürich Wound dressing and apparatus
WO1997046665A1 (en) * 1996-06-04 1997-12-11 Sulzer Orthopedics Ltd. Method for making cartilage and implants
US5919702A (en) * 1996-10-23 1999-07-06 Advanced Tissue Science, Inc. Production of cartilage tissue using cells isolated from Wharton's jelly
US5882929A (en) * 1998-04-07 1999-03-16 Tissue Engineering, Inc. Methods and apparatus for the conditioning of cartilage replacement tissue
FR2784284B1 (en) * 1998-10-13 2000-12-15 Natural Implant Sa PROCESS FOR THE PREPARATION OF A DENTAL IMPLANT BY IMMERSION IN A CULTURE OF MESENCHYMAL CELLS, CELL CULTURE DEVICE FOR THE PREPARATION OF SAID IMPLANT AND IMPLANT OBTAINED

Also Published As

Publication number Publication date
CN1507488A (en) 2004-06-23
FR2821853B1 (en) 2003-05-16
FR2821853A1 (en) 2002-09-13
EP1366145A1 (en) 2003-12-03
US7163825B2 (en) 2007-01-16
PL362575A1 (en) 2004-11-02
JP2004528832A (en) 2004-09-24
CN100408670C (en) 2008-08-06
US20040058434A1 (en) 2004-03-25
CA2439731A1 (en) 2002-09-19
WO2002072750A1 (en) 2002-09-19

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A E 9A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2103 DE 26/04/2011.