BR0114330A - (7-(3-carboxifenil)-4-cloroisoquinolin-1-il)guanidina - Google Patents

(7-(3-carboxifenil)-4-cloroisoquinolin-1-il)guanidina

Info

Publication number
BR0114330A
BR0114330A BR0114330-1A BR0114330A BR0114330A BR 0114330 A BR0114330 A BR 0114330A BR 0114330 A BR0114330 A BR 0114330A BR 0114330 A BR0114330 A BR 0114330A
Authority
BR
Brazil
Prior art keywords
chloroisoquinolin
guanidine
carboxyphenyl
carboxyphyl
intermediates
Prior art date
Application number
BR0114330-1A
Other languages
English (en)
Inventor
Anne Bruckner
Michael Butters
Paul Vincent Fish
Michael Paul Fitzgerald
Julie Ann Macrae
Trevor Jack Newbury
Richard Anthony Storey
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BR0114330A publication Critical patent/BR0114330A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

"(7-(3-CARBOXIFENIL)-4-CLOROISOQUINOLIN-1-IL)GUANIDINA" . A presente invenção descrita refere-se a um processo para a preparação de (7-(3-carboxifenil)-4-cloroisoquinolin-1-il)guanidina (I), com os intermediários desta e com as suas formas e formulações novas, incluindo o zwitteríon monohidrato de (I), apropriadas para utilização farmacêutica.
BR0114330-1A 2000-10-30 2001-10-16 (7-(3-carboxifenil)-4-cloroisoquinolin-1-il)guanidina BR0114330A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0026490.3A GB0026490D0 (en) 2000-10-30 2000-10-30 Process
PCT/IB2001/002004 WO2002036571A1 (en) 2000-10-30 2001-10-16 (7-(3-carboxyphenyl)-4-chloroisoquinolin-1-yl)guanidine

Publications (1)

Publication Number Publication Date
BR0114330A true BR0114330A (pt) 2003-08-26

Family

ID=9902194

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0114330-1A BR0114330A (pt) 2000-10-30 2001-10-16 (7-(3-carboxifenil)-4-cloroisoquinolin-1-il)guanidina

Country Status (16)

Country Link
US (1) US6645979B2 (pt)
EP (1) EP1330439A1 (pt)
JP (1) JP2004513119A (pt)
AP (1) AP2001002320A0 (pt)
AU (1) AU2002210820A1 (pt)
BR (1) BR0114330A (pt)
CA (1) CA2427613A1 (pt)
GB (1) GB0026490D0 (pt)
HN (1) HN2001000246A (pt)
MX (1) MXPA03003928A (pt)
PA (1) PA8528801A1 (pt)
PE (1) PE20020517A1 (pt)
SV (1) SV2003000707A (pt)
TN (1) TNSN01152A1 (pt)
UY (1) UY26986A1 (pt)
WO (1) WO2002036571A1 (pt)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2128601C (en) * 1992-01-31 2003-07-15 Hiroyuki Nagano Quinolone carboxylic acid derivatives in crystalline hydrate form
DE69431222T2 (de) 1993-06-07 2003-04-17 Mitsui Chemicals Inc Übergangsmetallverbindung, und diese enthaltender Polymerisationkatalysator
GB9721964D0 (en) * 1997-10-16 1997-12-17 Pfizer Ltd Isoquinolines

Also Published As

Publication number Publication date
HN2001000246A (es) 2002-05-08
MXPA03003928A (es) 2003-08-19
EP1330439A1 (en) 2003-07-30
AP2001002320A0 (en) 2001-12-31
PE20020517A1 (es) 2002-06-20
CA2427613A1 (en) 2002-05-10
WO2002036571A1 (en) 2002-05-10
UY26986A1 (es) 2002-06-20
TNSN01152A1 (en) 2005-11-10
GB0026490D0 (en) 2000-12-13
AU2002210820A1 (en) 2002-05-15
US20020077336A1 (en) 2002-06-20
SV2003000707A (es) 2003-01-13
US6645979B2 (en) 2003-11-11
PA8528801A1 (es) 2002-08-26
JP2004513119A (ja) 2004-04-30

Similar Documents

Publication Publication Date Title
BR0214243A (pt) Derivado de sulfonamida processo para a preparação de um derivado de sulfonamida e seus sais fisiologicamente aceitáveis, composição farmacêutica e uso de um derivado de sulfonamida
BR9808540A (pt) Composto, processo para a preparação do mesmo, composição farmacêutica e processo para preparação dos mesmos, uso de um composto, e, processo para produzir a imunossupressão
BR0111913A (pt) Análogos de gabapentina para distúrbios do sono
BRPI0407430A (pt) Sal do ácido benzenossulfÈnico com clopidogrel, processos para preparação do mesmo, e para purificação de clopidogrel, uso de um sal, formulação farmacêutica, partìculas de substância ativa, uso de partìculas de substância ativa, e, processo para preparação de partìculas de substância ativa
CL2003002683A1 (es) Enantiomeros s de compuestos derivados del acido (2s)-3-4(-{2-amino-2-oxoetoxi}fenil)-2-etoxipropanoico; proceso de preparacion; compuestos intermediarios; composicion farmaceutica; y su uso para el tratamiento o prevencion de trastornos de lipidos,
BRPI0507877A (pt) derivados de formamida, composição farmacêutica, uso dos mesmos e combinação
BRPI0415424A (pt) processo para preparação de composto de aminocrotonila
EA200100524A1 (ru) Амиды антраниловой кислоты и их применение в качестве лекарственных средств
BR9806784A (pt) Modificações do 2-amino-4-(4-fluorobenzilamino)-1-etoxicarbonilamin obenzeno, bem como processo para a sua preparação
BR0209580A (pt) Derivados de ciclohexan-1, 4 diamina substituìdos
BR0113520A (pt) Processo de preparação de ácidos n-aril-antranìlicos e seus derivados
BRPI0108395B8 (pt) derivados de pirrolopirimidinona, processos de preparação e uso
BRPI0410029B8 (pt) composto dihidroquinazolina substituído, processo para sua preparação, medicamento compreendendo o referido composto e uso do referido composto
BR0108678A (pt) Novos compostos
BR0310077A (pt) Novos compostos e sua utilização
BR0309743A (pt) Processo para a preparação de gama-butirolactamas e gama-aminoácidos altamente funcionalizados
SE0100569D0 (sv) New compounds
BR0209845A (pt) Formas de dosagem de oxcarbazepina e processo para a preparação das mesmas
BR0009411A (pt) Composto de anilina substituìda, e, processo para a preparação e uso de compostos
BRPI0410391A (pt) derivados (2-hidróxi-2-(4-hidróxi-3-hidroximetilfenil)-etilamino)- propilfenila como agonistas beta2
BR0211761A (pt) depsipeptìdeos e processos para preparar os mesmos
BR0211063A (pt) Sais de derivados anticonvulsivantes
BR0011700A (pt) Dinitrilas de ácido arilmalÈnico substituìdo como intermediários para a preparação de herbicidas
BR9812062A (pt) Composto, uso deste, processo para prepará-lo, enanciÈmero único purificado, composição farmacêutica, e, processos para tratamento de bronquite crÈnica ou de doença pulmonar obstrutiva crÈnica em um indivìduo humano ou animal, e para tratamento de asma em um indivìduo humano ou animal
SE0102440D0 (sv) New compound

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 1964 DE 26/08/2008 E CONSIDERANDO A AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS.