BR0113460A - Solução tópica com estabilidade a longo prazo - Google Patents

Solução tópica com estabilidade a longo prazo

Info

Publication number
BR0113460A
BR0113460A BR0113460-4A BR0113460A BR0113460A BR 0113460 A BR0113460 A BR 0113460A BR 0113460 A BR0113460 A BR 0113460A BR 0113460 A BR0113460 A BR 0113460A
Authority
BR
Brazil
Prior art keywords
term stability
long term
topical solution
chelating agent
long
Prior art date
Application number
BR0113460-4A
Other languages
English (en)
Inventor
Prakash V Parab
Original Assignee
Galderma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Sa filed Critical Galderma Sa
Publication of BR0113460A publication Critical patent/BR0113460A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/51—Chelating agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

"SOLUçãO TóPICA COM ESTABILIDADE A LONGO PRAZO". A presente invenção refere-se a uma composição de tretinoína e 4-hidroxianisol, estável de armazenamento a longo prazo que contém polietilenoglicol de baixo peso molecular, um agente quelante, um alcanol inferior e água. O agente quelante confere pelo menos duas das funções de seq³estro de oxigênio e radicais livres de terminação de cadeia e redução. A composição possui um pH de 2,5 a 5 e o teor de água de pelo menos 12%.
BR0113460-4A 2000-08-24 2001-08-03 Solução tópica com estabilidade a longo prazo BR0113460A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/644,912 US6353029B1 (en) 2000-08-24 2000-08-24 Storage stable tretinoin and 4-hydroxyanisole containing topical composition
PCT/US2001/024287 WO2002015851A2 (en) 2000-08-24 2001-08-03 Storage stable tretinoin and 4-hydroxy anisole containing topical composition

Publications (1)

Publication Number Publication Date
BR0113460A true BR0113460A (pt) 2003-07-15

Family

ID=24586862

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0113460-4A BR0113460A (pt) 2000-08-24 2001-08-03 Solução tópica com estabilidade a longo prazo

Country Status (13)

Country Link
US (1) US6353029B1 (pt)
EP (1) EP1313442A2 (pt)
JP (1) JP2004506666A (pt)
KR (1) KR20030048016A (pt)
CN (1) CN1225247C (pt)
AU (1) AU8100301A (pt)
BR (1) BR0113460A (pt)
CA (1) CA2419877C (pt)
MX (1) MXPA03001552A (pt)
PL (1) PL365681A1 (pt)
RU (1) RU2270002C2 (pt)
WO (1) WO2002015851A2 (pt)
ZA (1) ZA200300704B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7241808B2 (en) * 2002-05-01 2007-07-10 Marvin Klein Composition for treatment of skin and method for stabilizing the composition
US7491234B2 (en) * 2002-12-03 2009-02-17 Boston Scientific Scimed, Inc. Medical devices for delivery of therapeutic agents
EP1572176A2 (en) * 2002-12-12 2005-09-14 Galderma Research & Development, S.N.C. Aqueous-alcoholic depigmenting gel containing a phenolic derivative and a retinoid
FR2870123A1 (fr) * 2004-05-14 2005-11-18 Galderma Res & Dev Composition dermatologique depigmentante a base de mequinol
FR2870122A1 (fr) * 2004-05-14 2005-11-18 Galderma Res & Dev Composition pharmaceutique ou cosmetique comprenant du mequinol et au moins un agent depigmentant
FR2871377B1 (fr) * 2004-06-11 2007-08-24 Galderma Res & Dev Gel depigmentant hydroalcoolique comprenant du mequinol et de l'adapalene
JP5406531B2 (ja) * 2006-10-12 2014-02-05 ロート製薬株式会社 皮膚外用剤
US8070989B2 (en) * 2007-08-09 2011-12-06 Hallstar Innovations Corp. Photostabilization of retinoids with alkoxycrylene compounds
JP4856125B2 (ja) * 2008-06-27 2012-01-18 祐徳薬品工業株式会社 安定化されたフェンタニルまたはその塩含有組成物及びこれを用いた医薬製剤並びにフェンタニルまたはその塩の安定化方法
CN102076340B (zh) * 2008-06-27 2013-01-23 祐德药品工业株式会社 含芬太尼或其盐的经皮吸收型贴剂
RU2514414C1 (ru) * 2012-12-14 2014-04-27 Закрытое акционерное общество "Аметис" Антиоксидантный премикс и способ его производства
CA2929292C (en) 2013-10-31 2021-11-02 Sun Pharmaceutical Industries Limited Topical pharmaceutical composition of acitretin
US11826466B2 (en) * 2016-08-31 2023-11-28 Navinta, Llc Bendamustine solution formulations
WO2023015378A1 (en) * 2021-08-09 2023-02-16 CannTab Therapeutics Limited Stabilization of cannabis resin and solid oral cannabinoid formulations

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69029804T2 (de) * 1989-06-07 1997-09-04 Gail S Bazzano VEHIKEL MIT LANGSAMER FREISETZUNG ZUR VERMINDERUNG DER HAUTREIZUNG TOPISCHER retinoidhaltiger MITTEL
US5470567A (en) 1989-08-24 1995-11-28 Bristol Myers Squibb Company Synergistic skin depigmentation composition
US5194247A (en) 1989-08-24 1993-03-16 Xina Nair Synergistic skin depigmentation composition
US5326566A (en) * 1991-05-17 1994-07-05 Bristol-Myers Squibb Company Use of dibutyl adipate and isopropyl myristate in topical and transdermal products
WO1994001074A1 (en) * 1992-07-13 1994-01-20 Shiseido Company, Ltd. Composition for dermatologic preparation
CA2143515A1 (en) * 1994-03-22 1995-09-23 Prakash Parab Method for enhancing the rate of skin permeation of lactic acid through use of the l-enantiomer
US5420106A (en) * 1994-03-22 1995-05-30 Bristol-Myers Squibb Company Method and composition having enhanced alpha-hydroxy acid skin permeation and retention
FR2718021B1 (fr) * 1994-04-05 1996-06-28 Fabre Pierre Cosmetique Composition topique à base de rétinal.
US5786344A (en) * 1994-07-05 1998-07-28 Arch Development Corporation Camptothecin drug combinations and methods with reduced side effects
US6008254A (en) 1997-05-09 1999-12-28 Kligman; Douglas E. Method of treating skin disorders with high-strength tretinoin

Also Published As

Publication number Publication date
CN1225247C (zh) 2005-11-02
CA2419877C (en) 2009-11-24
ZA200300704B (en) 2004-02-17
KR20030048016A (ko) 2003-06-18
PL365681A1 (en) 2005-01-10
CA2419877A1 (en) 2002-02-28
JP2004506666A (ja) 2004-03-04
US6353029B1 (en) 2002-03-05
EP1313442A2 (en) 2003-05-28
RU2270002C2 (ru) 2006-02-20
CN1447681A (zh) 2003-10-08
WO2002015851A3 (en) 2002-07-25
MXPA03001552A (es) 2003-06-06
WO2002015851A2 (en) 2002-02-28
AU8100301A (en) 2002-03-04

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6O, 7O E 8O ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2021 DE 29/09/2009.

B15K Others concerning applications: alteration of classification

Ipc: A61K 8/67 (2006.01), A61K 8/34 (2006.01), A61K 8/3