BR0113330A - Method for producing one or more proteins, library of labeled proteins, method for producing a protein array, arrangement, methods for screening one or more compounds for biological activity, one or more proteins for protein-protein interactions and specific nucleic acid protein, use of an array, methods of generating an antibody array, and screening for abundance or function of proteins, and use of a labeled protein - Google Patents

Method for producing one or more proteins, library of labeled proteins, method for producing a protein array, arrangement, methods for screening one or more compounds for biological activity, one or more proteins for protein-protein interactions and specific nucleic acid protein, use of an array, methods of generating an antibody array, and screening for abundance or function of proteins, and use of a labeled protein

Info

Publication number
BR0113330A
BR0113330A BR0113330-6A BR0113330A BR0113330A BR 0113330 A BR0113330 A BR 0113330A BR 0113330 A BR0113330 A BR 0113330A BR 0113330 A BR0113330 A BR 0113330A
Authority
BR
Brazil
Prior art keywords
protein
proteins
array
methods
labeled
Prior art date
Application number
BR0113330-6A
Other languages
Portuguese (pt)
Inventor
Jonathan Michael Blackburn
Michele Anne Mulder
Mitali Samaddar
Roland Zbignieiw Kozlowski
Original Assignee
Procognia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0020357A external-priority patent/GB0020357D0/en
Application filed by Procognia Ltd filed Critical Procognia Ltd
Publication of BR0113330A publication Critical patent/BR0113330A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)

Abstract

"MéTODO PARA PRODUçãO DE UMA OU MAIS PROTEìNAS, BIBLIOTECA DE PROTEìNAS ROTULADAS, MéTODO PARA A PRODUçãO DE UM ARRANJO DE PROTEìNAS, ARRANJO, MéTODOS DE TRIAGEM DE UM OU MAIS COMPOSTOS PARA ATIVIDADE BIOLóGICA DE UMA OU MAIS PROTEìNAS PARA INTERAçõES DE PROTEìNA-PROTEìNA E DE PROTEìNA-áCIDO NUCLEICO ESPECìFICAS, USO DE UM ARRANJO, MéTODOS DE GERAçãO DE UM ARRANJO DE ANTICORPOS, E DE TRIAGEM DE ABUND NCIA OU FUNçãO DE PROTEìNA, E USO DE UMA PROTEìNA ROTULADA". A presente invenção refere-se aos novos métodos de produção de proteínas nas quais um ou mais domínios são de comprimento total e estão corretamente dobrados e estão, cada um, rotulados ou na terminação N ou na terminação C com um ou mais grupos rotuladores, e aos arranjos contendo tais proteínas, bem como ao uso de tais proteínas em arranjos de triagem rápida."METHOD FOR PRODUCTION OF ONE OR MORE PROTEINS, LIBRARY OF LABELED PROTEINS, METHOD FOR PRODUCTION OF A PROTEIN ARRANGEMENT, ARRANGEMENT, METHODS FOR SCREENING ONE OR MORE COMPOSITION FOR INTERNAL PROTOIN BIOGRAPHY SPECIFIC NUCLEIC ACID PROTECTION, USE OF A ARRANGEMENT, METHODS FOR GENERATING AN ANTIBODY ARRANGEMENT, AND ABUNDANCE OR PROTEIN FUNCTION SCREENING, AND USE OF A LABELED PROTEIN ". The present invention relates to novel protein production methods in which one or more domains are full length and correctly folded and are each labeled either at the N-terminus or C-terminus with one or more labeling groups, and arrangements containing such proteins as well as the use of such proteins in rapid sorting arrangements.

BR0113330-6A 2000-08-17 2001-08-17 Method for producing one or more proteins, library of labeled proteins, method for producing a protein array, arrangement, methods for screening one or more compounds for biological activity, one or more proteins for protein-protein interactions and specific nucleic acid protein, use of an array, methods of generating an antibody array, and screening for abundance or function of proteins, and use of a labeled protein BR0113330A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0020357A GB0020357D0 (en) 2000-08-17 2000-08-17 Method
US24799500P 2000-11-14 2000-11-14
PCT/GB2001/003693 WO2002027327A2 (en) 2000-08-17 2001-08-17 Rapid profiling of the interactions between a chemical entity and proteins in a given proteome

Publications (1)

Publication Number Publication Date
BR0113330A true BR0113330A (en) 2003-12-30

Family

ID=26244855

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0113330-6A BR0113330A (en) 2000-08-17 2001-08-17 Method for producing one or more proteins, library of labeled proteins, method for producing a protein array, arrangement, methods for screening one or more compounds for biological activity, one or more proteins for protein-protein interactions and specific nucleic acid protein, use of an array, methods of generating an antibody array, and screening for abundance or function of proteins, and use of a labeled protein

Country Status (10)

Country Link
EP (1) EP1326970A2 (en)
JP (1) JP2004509645A (en)
KR (1) KR20030043933A (en)
CN (1) CN1494589A (en)
AU (1) AU2001279948A1 (en)
BR (1) BR0113330A (en)
CA (1) CA2420415A1 (en)
GB (1) GB2384779B (en)
IL (1) IL154486A0 (en)
WO (1) WO2002027327A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0202018D0 (en) 2002-01-29 2002-03-13 Sense Proteomic Ltd Tag and method
ES2290556T3 (en) * 2002-10-25 2008-02-16 Sense Proteomic Limited NEW USES OF PROTEINS CODED BY BLE GENES AND ANTIBIOTICS OF THE BLEOMYCINE FAMILY.
US20060094059A1 (en) * 2004-09-22 2006-05-04 Odyssey Thera, Inc. Methods for identifying new drug leads and new therapeutic uses for known drugs
GB2460717A (en) 2008-06-11 2009-12-16 Sense Proteomic Ltd Autoantibodies for the detection of a predisposition to Lupus
GB2478734A (en) 2010-03-15 2011-09-21 Sense Proteomic Ltd Auto-antibody biomarkers of prostate cancer
GB201017520D0 (en) 2010-10-15 2010-12-01 Sense Proteomic Ltd Biomarkers

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE311443T1 (en) * 1997-09-03 2005-12-15 Biovation Ltd METHODS FOR SCREENING PROTEINS
CA2319828A1 (en) * 1998-01-29 1999-08-05 Miller, Samuel High density arrays for proteome analysis and methods and compositions therefor
CA2323638A1 (en) * 1998-04-03 1999-10-14 Phylos, Inc. Addressable protein arrays
US6406921B1 (en) * 1998-07-14 2002-06-18 Zyomyx, Incorporated Protein arrays for high-throughput screening
CA2339817A1 (en) * 1998-08-12 2000-02-24 Zycos Inc. Profiling and cataloging expressed protein tags
AU778194B2 (en) * 1999-07-12 2004-11-18 Bristol-Myers Squibb Company C-terminal protein tagging
IL145689A0 (en) * 2000-01-31 2002-06-30 Sense Proteomic Ltd Methods

Also Published As

Publication number Publication date
CN1494589A (en) 2004-05-05
EP1326970A2 (en) 2003-07-16
GB2384779A (en) 2003-08-06
AU2001279948A1 (en) 2002-04-08
GB2384779B (en) 2004-09-29
CA2420415A1 (en) 2002-04-04
GB0306057D0 (en) 2003-04-23
JP2004509645A (en) 2004-04-02
KR20030043933A (en) 2003-06-02
WO2002027327A3 (en) 2003-04-17
IL154486A0 (en) 2003-09-17
WO2002027327A2 (en) 2002-04-04

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A,6AE7A ANUIDADE

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1963 DE 19.08.2008.