BR0112267A - Compound, pharmaceutical formulation, use of a compound, method of prophylaxis or treatment of an arrhythmia, and process for the preparation of a compound - Google Patents

Compound, pharmaceutical formulation, use of a compound, method of prophylaxis or treatment of an arrhythmia, and process for the preparation of a compound

Info

Publication number
BR0112267A
BR0112267A BR0112267-3A BR0112267A BR0112267A BR 0112267 A BR0112267 A BR 0112267A BR 0112267 A BR0112267 A BR 0112267A BR 0112267 A BR0112267 A BR 0112267A
Authority
BR
Brazil
Prior art keywords
compound
treatment
prophylaxis
pharmaceutical formulation
arrhythmia
Prior art date
Application number
BR0112267-3A
Other languages
Portuguese (pt)
Inventor
Kjell Andersson
Annika Bj Re
Magnus Bjorsne
Fritiof Ponten
Gert Strandlund
Peder Svensson
Louise Tottie
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0002603A external-priority patent/SE0002603D0/en
Priority claimed from SE0002788A external-priority patent/SE0002788D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BR0112267A publication Critical patent/BR0112267A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"COMPOSTO, FORMULAçãO FARMACêUTICA, USO DE UM COMPOSTO, MéTODO DE PROFILAXIA OU TRATAMENTO DE UMA ARRITMIA, E, PROCESSO PARA A PREPARAçãO DE UM COMPOSTO". São fornecidos compostos de fórmula (I) em que R^ 1^, R^ 2^, R^ 3a^ e R^ 3b^ e R^ 41^ a R^ 46^ possuem os significados dados na descrição, que são úteis na profilaxia e no tratamento de arritmias, em particular, em arritmias atriais e ventriculares."COMPOUND, PHARMACEUTICAL FORMULATION, USE OF A COMPOUND, PROPHYLAXY METHOD OR TREATMENT OF AN ARRYTHMIA, AND PROCESS FOR PREPARING A COMPOUND". Compounds of formula (I) are provided wherein R 1, R 2, R 3a and R 3b and R 41 a to R 46 have the meanings given in the description which are useful in prophylaxis and treatment of arrhythmias, in particular in atrial and ventricular arrhythmias.

BR0112267-3A 2000-07-07 2001-07-04 Compound, pharmaceutical formulation, use of a compound, method of prophylaxis or treatment of an arrhythmia, and process for the preparation of a compound BR0112267A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0002603A SE0002603D0 (en) 2000-07-07 2000-07-07 New compounds
SE0002788A SE0002788D0 (en) 2000-07-27 2000-07-27 New compounds
PCT/SE2001/001544 WO2002004446A1 (en) 2000-07-07 2001-07-04 New bispidine compounds and their use in the treatment of cardiac arrhythmias

Publications (1)

Publication Number Publication Date
BR0112267A true BR0112267A (en) 2003-05-20

Family

ID=26655177

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0112267-3A BR0112267A (en) 2000-07-07 2001-07-04 Compound, pharmaceutical formulation, use of a compound, method of prophylaxis or treatment of an arrhythmia, and process for the preparation of a compound

Country Status (20)

Country Link
EP (1) EP1301510A1 (en)
JP (1) JP2004502772A (en)
KR (1) KR20030014426A (en)
CN (1) CN1440407A (en)
AR (1) AR030302A1 (en)
AU (1) AU2001271161A1 (en)
BR (1) BR0112267A (en)
CA (1) CA2412848A1 (en)
CZ (1) CZ200332A3 (en)
EE (1) EE200300013A (en)
HU (1) HUP0301304A2 (en)
IL (1) IL153485A0 (en)
IS (1) IS6660A (en)
MX (1) MXPA02012942A (en)
NO (1) NO20030057L (en)
NZ (1) NZ523540A (en)
PL (1) PL360474A1 (en)
RU (1) RU2002134450A (en)
SK (1) SK42003A3 (en)
WO (1) WO2002004446A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004103991A1 (en) * 2003-05-20 2004-12-02 'chemical Diversity Research Institute', Ltd. 2-substituted piperidines, focused library and a pharmaceutical compound
US7399765B2 (en) 2003-09-19 2008-07-15 Abbott Laboratories Substituted diazabicycloalkane derivatives
SE0302775D0 (en) * 2003-10-20 2003-10-20 Astrazeneca Ab Chemical compound and assay
RU2472793C1 (en) * 2011-07-20 2013-01-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет тонких химических технологий имени М.В. Ломоносова" (МИТХТ им.М.В.Ломоносова) 1,5-bis[(tert-butylamino)methyl]-n,n'-di-tert-butylbispidin-9-one and method for production thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3732094A1 (en) * 1987-09-24 1989-04-06 Basf Ag BISPID DERIVATIVES AS CLASS III ANTIARRHYTHMICS
US5110933A (en) * 1989-11-13 1992-05-05 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
US5468858A (en) * 1993-10-28 1995-11-21 The Board Of Regents Of Oklahoma State University Physical Sciences N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents
DE4402931A1 (en) * 1994-02-01 1995-08-03 Kali Chemie Pharma Gmbh New drugs containing 3-phenylsulfonyl-3,7-diazabicyclo [3,3,1] nonane compounds
DE4402933A1 (en) * 1994-02-01 1995-08-03 Kali Chemie Pharma Gmbh New drugs containing 3-benzoyl-3,7-diazabicyclo [3,3,1] nonane compounds
SE9704709D0 (en) * 1997-12-17 1997-12-17 Astra Ab Pharmaceutically active compounds
SE9902269D0 (en) * 1999-06-16 1999-06-16 Astra Ab Pharmaceutically active compounds
SE9902268D0 (en) * 1999-06-16 1999-06-16 Astra Ab Pharmaceutically active compounds
SE9902271D0 (en) * 1999-06-16 1999-06-16 Astra Ab Pharmaceutically active compounds
SE9902270D0 (en) * 1999-06-16 1999-06-16 Astra Ab Pharmaceutically active compounds

Also Published As

Publication number Publication date
EE200300013A (en) 2004-10-15
MXPA02012942A (en) 2003-10-06
KR20030014426A (en) 2003-02-17
AU2001271161A1 (en) 2002-01-21
CN1440407A (en) 2003-09-03
CZ200332A3 (en) 2003-04-16
EP1301510A1 (en) 2003-04-16
JP2004502772A (en) 2004-01-29
NZ523540A (en) 2004-07-30
NO20030057L (en) 2003-01-31
IS6660A (en) 2002-12-19
IL153485A0 (en) 2003-07-06
CA2412848A1 (en) 2002-01-17
RU2002134450A (en) 2004-07-10
AR030302A1 (en) 2003-08-20
HUP0301304A2 (en) 2003-08-28
PL360474A1 (en) 2004-09-06
WO2002004446A1 (en) 2002-01-17
SK42003A3 (en) 2003-07-01
NO20030057D0 (en) 2003-01-06

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A,6A E 7A ANUIDADE

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1963 DE 19.08.2008.