BR0110822A - Processo para produção de derivados de arilpoli(oxalquil)benzildimetil-amÈnio - Google Patents
Processo para produção de derivados de arilpoli(oxalquil)benzildimetil-amÈnioInfo
- Publication number
- BR0110822A BR0110822A BR0110822-0A BR0110822A BR0110822A BR 0110822 A BR0110822 A BR 0110822A BR 0110822 A BR0110822 A BR 0110822A BR 0110822 A BR0110822 A BR 0110822A
- Authority
- BR
- Brazil
- Prior art keywords
- alkyl
- oxalkyl
- production
- arylpoly
- ammonium derivatives
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- XXBDWLFCJWSEKW-UHFFFAOYSA-N dimethylbenzylamine Chemical class CN(C)CC1=CC=CC=C1 XXBDWLFCJWSEKW-UHFFFAOYSA-N 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000002877 alkyl aryl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
"PROCESSO PARA PRODUçãO DE DERIVADOS DE ARILPOLI(OXALQUIL)-BENZILDIMETIL-AMÈNIO". A invenção refere-se a um processo para produção de derivados de arilpoli(oxalquil)benzildimetil-amónio da fórmula (1) por reação de compostos das fórmulas (2) e (3), em que X = Br, CI, R-SO~ 3~, com R = alquila, alquilarila; R~ 1~ = H, C~ 1~- a C~ 16~-alquila ou O-C~ 1~ a O-C~ 16~-alquila, em posição orto, meta ou para; R~ 2~ = H, C~ 1~- a C~ 4~-alquila ou O-C~ 1~- a O-C~ 4~-alquila; R~ 3~ = H, C~ 1~- a C~ 16~-alquila ou O-C~ 1~- a O-C~ 16~-aquila em posição orto, meta ou para, e n = 1, 2, 3 ou 4, a temperaturas de 60 a 160<198>C, em um solvente, sob a pressão que se forma em um recipiente de reação fechado.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10023955A DE10023955C2 (de) | 2000-05-16 | 2000-05-16 | Verfahren zur Herstellung von Arylpoly(oxalkyl)benzyldimethylammoniumderivaten |
| PCT/EP2001/004963 WO2001087818A1 (de) | 2000-05-16 | 2001-05-03 | Verfahren zur herstellung von arylpoly(oxalkyl)-benzyldimethyl-ammoniumderivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0110822A true BR0110822A (pt) | 2003-02-11 |
Family
ID=7642252
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0110822-0A BR0110822A (pt) | 2000-05-16 | 2001-05-03 | Processo para produção de derivados de arilpoli(oxalquil)benzildimetil-amÈnio |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6794543B2 (pt) |
| EP (1) | EP1286950B1 (pt) |
| JP (1) | JP2003533501A (pt) |
| AT (1) | ATE309976T1 (pt) |
| BR (1) | BR0110822A (pt) |
| CA (1) | CA2401588A1 (pt) |
| DE (2) | DE10023955C2 (pt) |
| DK (1) | DK1286950T3 (pt) |
| ES (1) | ES2254449T3 (pt) |
| WO (1) | WO2001087818A1 (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7642323B2 (en) * | 1997-11-06 | 2010-01-05 | Nektar Therapeutics | Heterobifunctional poly(ethylene glycol) derivatives and methods for their preparation |
| EP1892235A1 (en) * | 2006-08-24 | 2008-02-27 | Dishman Pharmaceuticals & Chemicals Ltd. | Method for preparing arylpoly(oxyalkyl) amines |
| CN102993031B (zh) | 2011-09-19 | 2014-03-26 | 北京桑普生物化学技术有限公司 | 一种制备芳基多氧烷基季铵类化合物的方法 |
| CN113372227A (zh) * | 2021-06-29 | 2021-09-10 | 扬州虹光生物科技有限公司 | 一种高纯度苄索氯铵合成工艺 |
| CN117384050A (zh) * | 2023-10-12 | 2024-01-12 | 扬州市普林斯医药科技有限公司 | 一种医药级苄索氯铵的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2098203A (en) | 1937-11-02 | Aromatic polyether chloride | ||
| US2170111A (en) * | 1936-05-28 | 1939-08-22 | Rohm & Haas | Manufacture of amines |
| NL45585C (pt) * | 1936-05-28 | 1900-01-01 | ||
| US3875215A (en) * | 1971-07-19 | 1975-04-01 | Dow Chemical Co | Substituted phenoxyalkyl quaternary ammonium compounds |
| WO1993002040A1 (en) * | 1991-07-18 | 1993-02-04 | Eastman Kodak Company | Ether-containing quaternary ammonium salts |
-
2000
- 2000-05-16 DE DE10023955A patent/DE10023955C2/de not_active Expired - Fee Related
-
2001
- 2001-05-03 DE DE50108091T patent/DE50108091D1/de not_active Expired - Lifetime
- 2001-05-03 WO PCT/EP2001/004963 patent/WO2001087818A1/de active IP Right Grant
- 2001-05-03 JP JP2001584216A patent/JP2003533501A/ja not_active Withdrawn
- 2001-05-03 BR BR0110822-0A patent/BR0110822A/pt not_active IP Right Cessation
- 2001-05-03 US US10/276,210 patent/US6794543B2/en not_active Expired - Fee Related
- 2001-05-03 DK DK01951474T patent/DK1286950T3/da active
- 2001-05-03 CA CA002401588A patent/CA2401588A1/en not_active Abandoned
- 2001-05-03 EP EP01951474A patent/EP1286950B1/de not_active Expired - Lifetime
- 2001-05-03 ES ES01951474T patent/ES2254449T3/es not_active Expired - Lifetime
- 2001-05-03 AT AT01951474T patent/ATE309976T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2401588A1 (en) | 2001-11-22 |
| ES2254449T3 (es) | 2006-06-16 |
| WO2001087818A1 (de) | 2001-11-22 |
| DE10023955C2 (de) | 2002-08-14 |
| EP1286950A1 (de) | 2003-03-05 |
| DE10023955A1 (de) | 2001-11-22 |
| DK1286950T3 (da) | 2006-02-13 |
| US6794543B2 (en) | 2004-09-21 |
| US20030114533A1 (en) | 2003-06-19 |
| EP1286950B1 (de) | 2005-11-16 |
| DE50108091D1 (de) | 2005-12-22 |
| JP2003533501A (ja) | 2003-11-11 |
| ATE309976T1 (de) | 2005-12-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A, 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1963 DE 19/08/2008. |