BR0103001A - Comprimido e processo para produção do mesmo - Google Patents

Comprimido e processo para produção do mesmo

Info

Publication number
BR0103001A
BR0103001A BR0103001-9A BR0103001A BR0103001A BR 0103001 A BR0103001 A BR 0103001A BR 0103001 A BR0103001 A BR 0103001A BR 0103001 A BR0103001 A BR 0103001A
Authority
BR
Brazil
Prior art keywords
tablet
binder
producing
granular agglomerate
melt
Prior art date
Application number
BR0103001-9A
Other languages
English (en)
Inventor
Joseph R Luber
Frank J Bunick
Original Assignee
Johnson & Johnson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson & Johnson filed Critical Johnson & Johnson
Publication of BR0103001A publication Critical patent/BR0103001A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/265Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic, or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Patente de Invenção: "COMPRIMIDO E PROCESSO PARA PRODUçãO DO MESMO". Um comprimido e processo para produzir a mesma são fornecidos. O comprimido é feito de um aglomerado granular compreendendo uma mistura de pelo menos um ingrediente ativo e um aglutinante. O aglomerado granular é aquecido para fundir o aglutinante somente em ou próximo de sua superfície, e então resfriado tal que o aglutinante solidifique em uma fase substancialmente contínua, desse modo formando a camada fundida no lado externo do comprimido.
BR0103001-9A 2000-02-11 2001-02-12 Comprimido e processo para produção do mesmo BR0103001A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/502,594 US6258381B1 (en) 2000-02-11 2000-02-11 Tablet and process for making the same

Publications (1)

Publication Number Publication Date
BR0103001A true BR0103001A (pt) 2002-03-05

Family

ID=23998514

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0103001-9A BR0103001A (pt) 2000-02-11 2001-02-12 Comprimido e processo para produção do mesmo

Country Status (9)

Country Link
US (1) US6258381B1 (pt)
EP (1) EP1123699B1 (pt)
AR (1) AR027525A1 (pt)
AT (1) ATE361058T1 (pt)
BR (1) BR0103001A (pt)
CA (1) CA2335179C (pt)
DE (1) DE60128168T2 (pt)
ES (1) ES2286077T3 (pt)
PT (1) PT1123699E (pt)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
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US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
US20030060422A1 (en) 2001-08-31 2003-03-27 Balaji Venkataraman Tannate compositions and methods of treatment
US7049435B2 (en) 2002-03-08 2006-05-23 Tate & Lyle Public Limited Company Extractive methods for purifying sucralose
US6998480B2 (en) 2002-03-08 2006-02-14 Tate & Lyle Public Limited Company Process for improving sucralose purity and yield
US20050031686A1 (en) * 2002-03-25 2005-02-10 Truffini & Regge' Farmaceutici Srl Gastroresistant tablets for alimentary, dietetic and therapeutic use
US20040109889A1 (en) * 2002-12-04 2004-06-10 Bunick Frank J. Surface treatment composition for soft substrates
US20040258822A1 (en) * 2003-06-16 2004-12-23 Shyhyuan Liao Chilsonated sucralose product
US9241902B2 (en) * 2003-12-17 2016-01-26 R.P. Scherer Technologies, Llc Chewable soft capsules containing ungelatinized starch
US7750146B2 (en) * 2005-03-18 2010-07-06 Tate & Lyle Plc Granular sucralose
GB0515492D0 (en) * 2005-07-28 2005-08-31 Reckitt Benckiser Healthcare Improvements in or relating to compositions,articles and methods
US20070077300A1 (en) * 2005-09-30 2007-04-05 Wynn David W Oral compositions containing a salivation inducing agent
US20070264403A1 (en) * 2006-05-11 2007-11-15 Nehmer Warren L Sparkling agglomerated sweetener, and method of making it
US20090060983A1 (en) * 2007-08-30 2009-03-05 Bunick Frank J Method And Composition For Making An Orally Disintegrating Dosage Form
EP2217213B1 (en) * 2007-10-31 2017-05-24 Johnson & Johnson Consumer Inc. Orally disintegrative dosage form
AR070082A1 (es) * 2008-01-04 2010-03-10 Tate & Lyle Technology Ltd Metodo para la produccion de sucralosa
CN101977664B (zh) * 2008-03-20 2014-02-26 塔特和莱利技术有限公司 从叔酰胺溶剂中去除酸
US8436157B2 (en) * 2008-03-26 2013-05-07 Tate & Lyle Technology Limited Method for the production of sucralose
JP5653341B2 (ja) * 2008-04-03 2015-01-14 テート アンド ライル テクノロジー リミテッド スクラロース抽出効率に対する炭水化物濃度の影響
AR071134A1 (es) * 2008-04-03 2010-05-26 Tate & Lyle Technology Ltd Cristalizacion de sucralosa a partir de chorros que contienen sucralosa
WO2009124113A1 (en) * 2008-04-03 2009-10-08 Tate & Lyle Technology Ltd. Extraction of less polar impurities from sucralose containing aqueous feed streams
US8497367B2 (en) * 2008-04-03 2013-07-30 Tate & Lyle Technology Limited Sucralose purification process
GB2469158B (en) 2009-03-31 2011-09-28 Peter J Seaberg Base-assisted formation of tin-sucrose adducts
US8858210B2 (en) 2009-09-24 2014-10-14 Mcneil-Ppc, Inc. Manufacture of variable density dosage forms utilizing radiofrequency energy
US20110070286A1 (en) * 2009-09-24 2011-03-24 Andreas Hugerth Process for the manufacture of nicotine-comprising chewing gum and nicotine-comprising chewing gum manufactured according to said process
US8313768B2 (en) * 2009-09-24 2012-11-20 Mcneil-Ppc, Inc. Manufacture of tablet having immediate release region and sustained release region
US8343533B2 (en) 2009-09-24 2013-01-01 Mcneil-Ppc, Inc. Manufacture of lozenge product with radiofrequency
AU2015203155B2 (en) * 2009-09-24 2017-05-11 Mcneil-Ppc, Inc. Orally transformable tablets
GB2474311B (en) * 2009-10-12 2012-10-17 Tate & Lyle Technology Ltd Low temperature, single solvent process for the production of sucrose-6-ester
GB2474310B (en) 2009-10-12 2012-02-29 Tate & Lyle Technology Ltd Process for the production of sucrose-6-ester
GB201110520D0 (en) 2011-05-10 2011-08-03 Tate & Lyle Technology Ltd Extraction of carboxylic acids with tin compounds
US9511028B2 (en) 2012-05-01 2016-12-06 Johnson & Johnson Consumer Inc. Orally disintegrating tablet
US9445971B2 (en) 2012-05-01 2016-09-20 Johnson & Johnson Consumer Inc. Method of manufacturing solid dosage form
US9233491B2 (en) 2012-05-01 2016-01-12 Johnson & Johnson Consumer Inc. Machine for production of solid dosage forms
MX368159B (es) 2014-01-10 2019-09-20 Johnson & Johnson Consumer Inc Proceso para elaborar tabletas con el uso de radiofrecuencia y partículas disipativas revestidas.
US10493026B2 (en) 2017-03-20 2019-12-03 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles
CN108853038A (zh) * 2018-08-06 2018-11-23 成都通德药业有限公司 一种对乙酰氨基酚片及其制备工艺
WO2023200954A1 (en) 2022-04-13 2023-10-19 Aprecia Pharmaceuticals LLC System and method for additive manufacturing using an omnidirectional magnetic movement apparatus

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DK123806B (da) * 1970-06-08 1972-08-07 Pharmacia As Fremgangsmåde til fremstilling af tabletter eller piller med langsom afgivelse af et aktivt stof.
US4327076A (en) 1980-11-17 1982-04-27 Life Savers, Inc. Compressed chewable antacid tablet and method for forming same
EP0070127A3 (en) 1981-07-10 1983-08-17 Beecham Group Plc Tablets
US4609543A (en) 1983-11-14 1986-09-02 Nabisco Brands, Inc. Soft homogeneous antacid tablet
HU191246B (en) * 1984-02-21 1987-01-28 Alkaloida Vegyeszeti Gyara,Hu Process for producing oral pharmaceutical compositions of retaed activity
US4684534A (en) 1985-02-19 1987-08-04 Dynagram Corporation Of America Quick-liquifying, chewable tablet
US4828845A (en) 1986-12-16 1989-05-09 Warner-Lambert Company Xylitol coated comestible and method of preparation
NZ234587A (en) * 1989-08-04 1991-11-26 Mcneil Ppc Inc A chewable pharmaceutical tablet of compressed coated granules
JP2948317B2 (ja) 1991-05-28 1999-09-13 マクニール―ピーピーシー・インコーポレーテツド 噛める薬物投与用組成物
ES2096103T3 (es) 1992-01-13 1997-03-01 Pfizer Preparacion de comprimidos de resistencia incrementada.
US6177104B1 (en) * 1994-01-27 2001-01-23 The Board Of Regents Of The University Of Oklahoma Particulate support matrix for making a rapidly dissolving dosage form
US6024981A (en) 1997-04-16 2000-02-15 Cima Labs Inc. Rapidly dissolving robust dosage form
EP1017386A1 (en) 1997-10-02 2000-07-12 H. Lundbeck A/S GRANULAR PREPARATIONS OF 5-(2-ETHYL- 2$i(H)-TETRAZOL- 5-YL)-1-METHYL-1, 2,3,6-TETRAHYDROPYRIDINE
US6060078A (en) 1998-09-28 2000-05-09 Sae Han Pharm Co., Ltd. Chewable tablet and process for preparation thereof

Also Published As

Publication number Publication date
CA2335179A1 (en) 2001-08-11
EP1123699A3 (en) 2003-01-22
DE60128168T2 (de) 2008-01-03
DE60128168D1 (de) 2007-06-14
CA2335179C (en) 2008-12-02
US6258381B1 (en) 2001-07-10
ES2286077T3 (es) 2007-12-01
EP1123699A2 (en) 2001-08-16
ATE361058T1 (de) 2007-05-15
AR027525A1 (es) 2003-04-02
EP1123699B1 (en) 2007-05-02
PT1123699E (pt) 2007-06-22

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DA INT.CL: A61K 9/20

Ipc: A61K 9/20 (2009.01), A61K 47/44 (2009.01), A61K 47

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 11,13, 24 E 25 DA LPI

B15K Others concerning applications: alteration of classification

Free format text: PARA: INT. CI 461K 9/20, A61K 47/44, A61K 47/30, A61P 29/00

Ipc: A61K 9/20 (2010.01), A61K 47/44 (2010.01), A61K 47

B12B Appeal against refusal [chapter 12.2 patent gazette]