BR0016328A - Pró-drogas de fosfato de pseudomicina - Google Patents

Pró-drogas de fosfato de pseudomicina

Info

Publication number
BR0016328A
BR0016328A BR0016328-7A BR0016328A BR0016328A BR 0016328 A BR0016328 A BR 0016328A BR 0016328 A BR0016328 A BR 0016328A BR 0016328 A BR0016328 A BR 0016328A
Authority
BR
Brazil
Prior art keywords
pseudomycin
phosphate
phosphate prodrugs
prodrug
methylenoxycarbamate
Prior art date
Application number
BR0016328-7A
Other languages
English (en)
Inventor
Shu Hui Chen
Xicheng Sun
Yanzhi Zhang
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BR0016328A publication Critical patent/BR0016328A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

"PRó-DROGAS DE FOSFATO DE PSEUDOMICINA". Um pró-droga de pseudomicina representada pela estrutura (A) onde R1 é uma ligação de benziloxicarbamato de fosfato ou metilenoxicarbamato de fosfato é descrito. A pró-droga de fosfato demonstra atividade antifúngica com menos efeitos colaterais adversos que o composto de pseudomicina de origem.
BR0016328-7A 1999-12-13 2000-11-29 Pró-drogas de fosfato de pseudomicina BR0016328A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17046699P 1999-12-13 1999-12-13
PCT/US2000/030167 WO2001041534A2 (en) 1999-12-13 2000-11-29 Pseudomycin phosphate prodrugs

Publications (1)

Publication Number Publication Date
BR0016328A true BR0016328A (pt) 2002-08-27

Family

ID=22619957

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0016328-7A BR0016328A (pt) 1999-12-13 2000-11-29 Pró-drogas de fosfato de pseudomicina

Country Status (7)

Country Link
JP (1) JP2003515610A (pt)
AU (1) AU3071801A (pt)
BR (1) BR0016328A (pt)
CA (1) CA2396513A1 (pt)
MX (1) MXPA02005791A (pt)
NO (1) NO20022798D0 (pt)
WO (1) WO2001041534A2 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60038735T2 (de) * 1999-04-15 2009-07-02 Eli Lilly And Co., Indianapolis Pseudomycin analoge
PE20211305A1 (es) 2018-01-05 2021-07-20 Cybrexa 1 Inc Compuestos, composiciones y metodos para tratar enfermedades que involucren tejidos con enfermedades acidas o hipoxicas
JP2022541747A (ja) 2019-07-10 2022-09-27 サイブレクサ ３，インコーポレイテッド 治療薬としての微小管標的化剤のペプチドコンジュゲート
US11634508B2 (en) 2019-07-10 2023-04-25 Cybrexa 2, Inc. Peptide conjugates of cytotoxins as therapeutics

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5576298A (en) * 1992-11-30 1996-11-19 Research And Development Institute, Inc. At Montana State University Peptides from pseudomonas syringae possessing broad-spectrum antibiotic activity
HUP0202267A3 (en) * 1999-07-15 2002-11-28 Lilly Co Eli Pseudomycin amide and ester analogs, method for their preparation and pharmaceutical compositions comprising thereof

Also Published As

Publication number Publication date
NO20022798L (no) 2002-06-12
WO2001041534A2 (en) 2001-06-14
AU3071801A (en) 2001-06-18
MXPA02005791A (es) 2002-09-30
JP2003515610A (ja) 2003-05-07
WO2001041534A3 (en) 2001-11-22
NO20022798D0 (no) 2002-06-12
CA2396513A1 (en) 2001-06-14

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired