BR0011724A - ácido nucleico, sonda ou iniciador nucleotìdico, iniciador nucleotìdico, processos para amplificação de um ácido nucleico, para detecção da presença de um polipeptìdeo um ácido nucleico e para seleção de um composto ativo sobre o metabolismo do colesterol, kits de diagnóstico para a detecção da presença de um polipeptìdeo e de um ácido nucléico e para amplificação de um ácido nucleico, vetor recombinante, célula hospedeira recombinante, polipeptìdeo, anticorpo, composição farmacêutica e utilização de um ácido nucleico, de um vetor recombinante e de um polipeptìdeo - Google Patents
ácido nucleico, sonda ou iniciador nucleotìdico, iniciador nucleotìdico, processos para amplificação de um ácido nucleico, para detecção da presença de um polipeptìdeo um ácido nucleico e para seleção de um composto ativo sobre o metabolismo do colesterol, kits de diagnóstico para a detecção da presença de um polipeptìdeo e de um ácido nucléico e para amplificação de um ácido nucleico, vetor recombinante, célula hospedeira recombinante, polipeptìdeo, anticorpo, composição farmacêutica e utilização de um ácido nucleico, de um vetor recombinante e de um polipeptìdeoInfo
- Publication number
- BR0011724A BR0011724A BR0011724-2A BR0011724A BR0011724A BR 0011724 A BR0011724 A BR 0011724A BR 0011724 A BR0011724 A BR 0011724A BR 0011724 A BR0011724 A BR 0011724A
- Authority
- BR
- Brazil
- Prior art keywords
- nucleic acid
- polypeptide
- detecting
- recombinant vector
- primer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Obesity (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Child & Adolescent Psychology (AREA)
- Microbiology (AREA)
Abstract
"áCIDO NUCLéICO, SONDA OU INICIADOR NUCLEOTìDICO, INICIADOR NUCLEOTìDICO, PROCESSOS PARA AMPLIFICAçãO DE UM áCIDO NUCLEICO, PARA DETECçãO DA PRESENçA DE UM POLIPEPTìDEO UM áCIDO NUCLéICO E PARA SELEçãO DE UM COMPOSTO ATIVO SOBRE O METABOLISMO DO COLESTEROL, KITS DE DIAGNóSTICO PARA A DETECçãO DA PRESENçA DE UM POLIPEPTìDEO E DE UM áCIDO NUCLéICO E PARA AMPLIFICAçãO DE UM áCIDO NUCLéICO, VETOR RECOMBINANTE, CéLULA HOSPEDEIRA RECOMBINANTE, POLIPEPTìDEO, ANTICORPO COMPOSIçãO FARMACêUTICA E UTILIZAçãO DE UM áCIDO NUCLéICO, DE UM VETOR RECOMBINANTE E DE UM POLIPEPTìDEO". A invenção refere-se a ácidos nucleicos correspondendo a diferentes éxons e íntrons de gene ABC1 que é mostrado ser um gene causador de patologias ligadas à disfunção do metabolismo do colesterol causando doenças, como aterosclerose, mais particularmente perturbação do transporte reverso do colesterol, e, mais particularmente, de FHDs, como a doença de Tangier.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9907684A FR2795091B1 (fr) | 1999-06-17 | 1999-06-17 | Acides nucleiques et proteines du gene abc1 humain et leur application en therapie et diagnostic |
US14712899P | 1999-08-04 | 1999-08-04 | |
PCT/FR2000/001595 WO2000078970A1 (fr) | 1999-06-17 | 2000-06-08 | Acides nucleiques et proteines correspondant au gene abc1 humain |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0011724A true BR0011724A (pt) | 2002-03-26 |
Family
ID=26234994
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0011724-2A BR0011724A (pt) | 1999-06-17 | 2000-06-08 | ácido nucleico, sonda ou iniciador nucleotìdico, iniciador nucleotìdico, processos para amplificação de um ácido nucleico, para detecção da presença de um polipeptìdeo um ácido nucleico e para seleção de um composto ativo sobre o metabolismo do colesterol, kits de diagnóstico para a detecção da presença de um polipeptìdeo e de um ácido nucléico e para amplificação de um ácido nucleico, vetor recombinante, célula hospedeira recombinante, polipeptìdeo, anticorpo, composição farmacêutica e utilização de um ácido nucleico, de um vetor recombinante e de um polipeptìdeo |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1190063A1 (pt) |
JP (1) | JP2003503026A (pt) |
KR (1) | KR20020012279A (pt) |
AU (1) | AU5540800A (pt) |
BR (1) | BR0011724A (pt) |
CA (1) | CA2375771A1 (pt) |
HU (1) | HUP0204524A2 (pt) |
IL (1) | IL147071A0 (pt) |
MX (1) | MXPA01013062A (pt) |
NO (1) | NO20016089L (pt) |
WO (1) | WO2000078970A1 (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2367955C (en) | 1999-03-15 | 2009-05-19 | University Of British Columbia | Abc1 polypeptide and methods and reagents for modulating cholesterol levels |
AU2002210636A1 (en) * | 2000-10-31 | 2002-05-15 | Aventis Pharma S.A. | Polymorphic sequences of the human ABCA1 gene, their uses, detection methods and kits |
FR2815970A1 (fr) * | 2000-10-31 | 2002-05-03 | Aventis Pharma Sa | Sequences polymorphes du gene humain abca1, leurs utilisations, les methodes et kits de detection |
NZ556415A (en) * | 2002-01-02 | 2009-02-28 | Genentech Inc | Compositions and methods for the diagnosis and treatment of glioma tumor |
CN112442114A (zh) * | 2019-08-29 | 2021-03-05 | 渥太华Hdl药物研发公司 | 一种多肽及其应用 |
-
2000
- 2000-06-08 EP EP00940477A patent/EP1190063A1/fr not_active Withdrawn
- 2000-06-08 AU AU55408/00A patent/AU5540800A/en not_active Abandoned
- 2000-06-08 IL IL14707100A patent/IL147071A0/xx unknown
- 2000-06-08 BR BR0011724-2A patent/BR0011724A/pt not_active IP Right Cessation
- 2000-06-08 HU HU0204524A patent/HUP0204524A2/hu unknown
- 2000-06-08 WO PCT/FR2000/001595 patent/WO2000078970A1/fr not_active Application Discontinuation
- 2000-06-08 MX MXPA01013062A patent/MXPA01013062A/es unknown
- 2000-06-08 KR KR1020017016224A patent/KR20020012279A/ko not_active Application Discontinuation
- 2000-06-08 JP JP2001505712A patent/JP2003503026A/ja not_active Withdrawn
- 2000-06-08 CA CA002375771A patent/CA2375771A1/fr not_active Abandoned
-
2001
- 2001-12-13 NO NO20016089A patent/NO20016089L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2000078970A1 (fr) | 2000-12-28 |
NO20016089D0 (no) | 2001-12-13 |
MXPA01013062A (es) | 2002-06-04 |
IL147071A0 (en) | 2002-08-14 |
EP1190063A1 (fr) | 2002-03-27 |
NO20016089L (no) | 2002-02-15 |
AU5540800A (en) | 2001-01-09 |
JP2003503026A (ja) | 2003-01-28 |
HUP0204524A2 (hu) | 2003-04-28 |
CA2375771A1 (fr) | 2000-12-28 |
KR20020012279A (ko) | 2002-02-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Shim et al. | Nucleosome positioning by the winged helix transcription factor HNF3 | |
Colgan et al. | Adenosine and hypoxia-inducible factor signaling in intestinal injury and recovery | |
Zempleni | Uptake, localization, and noncarboxylase roles of biotin | |
Lum et al. | Expression of PKA inhibitor (PKI) gene abolishes cAMPmediated protection to endothelial barrier dysfunction | |
Ueta et al. | IKZF1, a new susceptibility gene for cold medicine–related Stevens-Johnson syndrome/toxic epidermal necrolysis with severe mucosal involvement | |
Zhang et al. | Localization of DNA protein-binding sites in the proximal and distal promoter regions of the mouse alpha-fetoprotein gene. | |
Honma et al. | Carbohydrate/fat ratio in the diet alters histone acetylation on the sucrase–isomaltase gene and its expression in mouse small intestine | |
Kikuchi et al. | Genome-wide analysis of epigenetic signatures for kidney-specific transporters | |
BR0114575A (pt) | Sonda de hibridização de ácido nucléico de filamento duplo, reação de amplificação e detecção em tempo real, e, ensaio para detectar uma seq ência alvo de ácido nucléico | |
Nan et al. | The biological functions of the methyl-CpG-binding protein MeCP2 and its implication in Rett syndrome | |
Lutz et al. | A farnesoid X receptor polymorphism predisposes to spontaneous bacterial peritonitis | |
Zimmerman et al. | Inhibition of elastase and other serine proteases by heterocyclic acylating agents. | |
NO962331D0 (no) | Beskyttelse av nukleinsyrer, samt analysefremgangsmåter | |
BR0011724A (pt) | ácido nucleico, sonda ou iniciador nucleotìdico, iniciador nucleotìdico, processos para amplificação de um ácido nucleico, para detecção da presença de um polipeptìdeo um ácido nucleico e para seleção de um composto ativo sobre o metabolismo do colesterol, kits de diagnóstico para a detecção da presença de um polipeptìdeo e de um ácido nucléico e para amplificação de um ácido nucleico, vetor recombinante, célula hospedeira recombinante, polipeptìdeo, anticorpo, composição farmacêutica e utilização de um ácido nucleico, de um vetor recombinante e de um polipeptìdeo | |
Müller et al. | A covalent protein–DNA 5′-product adduct is generated following AP lyase activity of human ALKBH1 (AlkB homologue 1) | |
Goulas et al. | An association study of a functional catalase gene polymorphism,− 262C→ T, and patients with Alzheimer's disease | |
Valiyaveettil et al. | In vitro efficacy of paraoxonase 1 from multiple sources against various organophosphates | |
Zheng et al. | Selective HAT inhibitors as mechanistic tools for protein acetylation | |
Behm et al. | Anthelmintic action—a metabolic approach (a review) | |
Hall et al. | Turnover of strains and intraclonal variation amongst Pseudomonas aeruginosa isolates from paediatric CF patients | |
Steffen et al. | Cation transport by the respiratory NADH: quinone oxidoreductase (complex I): facts and hypotheses | |
Faure et al. | Case report: Brincidofovir-induced reversible severe acute kidney injury in 2 solid-organ transplant for treatment of cytomegalovirus infection | |
Takahashi et al. | Association of SNPs and haplotypes in APOL1, 2 and 4 with schizophrenia | |
Antes et al. | The nuclear matrix protein CDP represses hepatic transcription of the human cholesterol-7α hydroxylase gene | |
Fatkins et al. | A spectrophotometric assay for histone deacetylase 8 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A, 6A, E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1929 DE 26/12/2007. |