BR0010934A - Peptìdeos n-alquilados possuindo atividade antiangiogênica - Google Patents
Peptìdeos n-alquilados possuindo atividade antiangiogênicaInfo
- Publication number
- BR0010934A BR0010934A BR0010934-7A BR0010934A BR0010934A BR 0010934 A BR0010934 A BR 0010934A BR 0010934 A BR0010934 A BR 0010934A BR 0010934 A BR0010934 A BR 0010934A
- Authority
- BR
- Brazil
- Prior art keywords
- xaa
- antiangiogenic activity
- alkylated peptides
- alkylated
- peptides
- Prior art date
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 230000001772 anti-angiogenic effect Effects 0.000 title abstract 2
- 230000033115 angiogenesis Effects 0.000 abstract 3
- 230000002401 inhibitory effect Effects 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Communicable Diseases (AREA)
- Physical Education & Sports Medicine (AREA)
- Vascular Medicine (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
"PEPTìDEOS N-ALQUILADOS POSSUINDO ATIVIDADE ANTIANGIOGêNICA". Peptídeos N-alquilados da fórmula (I) Xaa~ 1~-, Xaa~ 2~-, Xaa~ 3~-, Xaa~ 4~-, Xaa~ 5~-, Xaa~ 6~-, Xaa~ 7~-, Xaa~ 8~-, Xaa~ 9~, Xaa~ 10~-, Xaa~ 11~ são úteis para inibição da angiogenese. Também são reveladas composições para inibir a angiogenese e processos para inibir angiogenese em mamíferos.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44709999A | 1999-11-22 | 1999-11-22 | |
US70264900A | 2000-10-31 | 2000-10-31 | |
PCT/US2000/032105 WO2001038397A1 (en) | 1999-11-22 | 2000-11-22 | N-alkylated peptides having antiangiogenic activity |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0010934A true BR0010934A (pt) | 2002-12-17 |
Family
ID=27034850
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0010934-7A BR0010934A (pt) | 1999-11-22 | 2000-11-22 | Peptìdeos n-alquilados possuindo atividade antiangiogênica |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1242455A1 (pt) |
JP (1) | JP2003514920A (pt) |
AR (1) | AR026901A1 (pt) |
AU (1) | AU1791301A (pt) |
BR (1) | BR0010934A (pt) |
CA (1) | CA2386893A1 (pt) |
CO (1) | CO5261544A1 (pt) |
HK (1) | HK1050902A1 (pt) |
MX (1) | MXPA02005139A (pt) |
WO (1) | WO2001038397A1 (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020183242A1 (en) * | 2001-04-11 | 2002-12-05 | Jack Henkin | Peptide antiangiogenic drugs |
US20030125259A1 (en) | 2001-10-31 | 2003-07-03 | Fortuna Haviv | Octa- and nonapeptides having antiangiogenic activity |
US7169888B2 (en) | 2001-10-31 | 2007-01-30 | Abbott Laboratories | Tetra-, penta-, hexa- and heptapeptides having antiangiogenic activity |
US7001984B2 (en) | 2001-10-31 | 2006-02-21 | Abbott Laboratories | Di-, tri-, and tetra-peptides having antiangiogenic activity |
US20030119746A1 (en) * | 2001-10-31 | 2003-06-26 | Fortuna Haviv | Hepta-and octapeptides having antiangiogenic activity |
US7067490B2 (en) | 2001-10-31 | 2006-06-27 | Abbott Laboratories | Hepta-, Octa-and nonapeptides having antiangiogenic activity |
US7037897B2 (en) | 2001-10-31 | 2006-05-02 | Abbott Laboratories | TRI-, TETRA-, and penta-peptides having antiangiogenic activity |
US7122625B2 (en) | 2001-10-31 | 2006-10-17 | Abbott Laboratories | Hexa-, hepta-, and octapeptides having antiangiogenic activity |
US20030228365A1 (en) * | 2002-06-07 | 2003-12-11 | Fortuna Haviv | Pharmaceutical formulation |
JP5167473B2 (ja) | 2005-03-03 | 2013-03-21 | コヴェックス・テクノロジーズ・アイルランド・リミテッド | 抗血管新生化合物 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001502293A (ja) * | 1996-03-05 | 2001-02-20 | トーレイ パインズ インスティテュート フォー モレキュラー スタディーズ | 選択的にn―アルキル化されたペプチド模倣的コンビナトリアルライブラリおよびその中の化合物 |
IL126626A0 (en) * | 1996-05-03 | 1999-08-17 | Abbott Lab | Novel antiangiogenic peptides polynucleotides encoding same and methods for inhibiting angiogenesis |
PT918795E (pt) * | 1997-03-17 | 2005-02-28 | Abbott Lab | Droga antiangiogenica para tratar cancro artrite e retinopatia |
-
2000
- 2000-11-20 CO CO00088047A patent/CO5261544A1/es not_active Application Discontinuation
- 2000-11-22 EP EP00980685A patent/EP1242455A1/en active Pending
- 2000-11-22 JP JP2001540160A patent/JP2003514920A/ja not_active Withdrawn
- 2000-11-22 BR BR0010934-7A patent/BR0010934A/pt not_active IP Right Cessation
- 2000-11-22 AR ARP000106173A patent/AR026901A1/es unknown
- 2000-11-22 MX MXPA02005139A patent/MXPA02005139A/es not_active Application Discontinuation
- 2000-11-22 CA CA002386893A patent/CA2386893A1/en not_active Abandoned
- 2000-11-22 WO PCT/US2000/032105 patent/WO2001038397A1/en active Application Filing
- 2000-11-22 AU AU17913/01A patent/AU1791301A/en not_active Abandoned
-
2003
- 2003-02-17 HK HK03101124.4A patent/HK1050902A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
CO5261544A1 (es) | 2003-03-31 |
EP1242455A1 (en) | 2002-09-25 |
AU1791301A (en) | 2001-06-04 |
MXPA02005139A (es) | 2004-08-23 |
WO2001038397A1 (en) | 2001-05-31 |
HK1050902A1 (zh) | 2003-07-11 |
JP2003514920A (ja) | 2003-04-22 |
AR026901A1 (es) | 2003-03-05 |
CA2386893A1 (en) | 2001-05-31 |
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Legal Events
Date | Code | Title | Description |
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B08F | Application fees: dismissal - article 86 of industrial property law |
Free format text: REFERENTA A 6A E 7A ANUIDADES. |
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B08K | Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87) |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008. |