BR0009712A - Uso de um análogo de esteróide sexual que rompe o esteróide sexual que sinaliza ao timo, e composição para aumentar uma resposta imune a um antìgeno - Google Patents
Uso de um análogo de esteróide sexual que rompe o esteróide sexual que sinaliza ao timo, e composição para aumentar uma resposta imune a um antìgenoInfo
- Publication number
- BR0009712A BR0009712A BR0009712-8A BR0009712A BR0009712A BR 0009712 A BR0009712 A BR 0009712A BR 0009712 A BR0009712 A BR 0009712A BR 0009712 A BR0009712 A BR 0009712A
- Authority
- BR
- Brazil
- Prior art keywords
- sex steroid
- thymus
- antigen
- immune response
- increase
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Transplantation (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Mycology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
"USO DE UM ANáLOGO DE ESTERóIDE SEXUAL QUE ROMPE O ESTERóIDE SEXUAL QUE SINALIZA AO TIMO, E COMPOSIçãO PARA AUMENTAR UMA RESPOSTA IMUNE A UM ANTìGENO". A presente invenção fornece um método de modificação da constituição da população de células-T ou de aumento do numero de células-T em um indivíduo tendo população ou função de células-T deprimida ou anormal, o método compreendendo a interrupção da sinalização de esteróide sexual ao timo no indivíduo. A invenção pode ser usada para tratar um indivíduo que sofre de uma ampla ordem de doenças, por exemplo, câncer, infecção por HIV, doença auto-imune e de hipersensibilidade. Em adição, a presente invenção fornece métodos para aumentar uma resposta imune a um antígeno, para tratar uma doença auto-imune, e para diminuir a reação receptor-enxerto em um doador de transplante.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPP9778A AUPP977899A0 (en) | 1999-04-15 | 1999-04-15 | Improvement of t cell mediated immunity |
PCT/AU2000/000329 WO2000062657A2 (en) | 1999-04-15 | 2000-04-17 | Improvement of t cell mediated immunity |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0009712A true BR0009712A (pt) | 2002-04-30 |
Family
ID=3813977
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0009712-8A BR0009712A (pt) | 1999-04-15 | 2000-04-17 | Uso de um análogo de esteróide sexual que rompe o esteróide sexual que sinaliza ao timo, e composição para aumentar uma resposta imune a um antìgeno |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1191975A4 (pt) |
JP (1) | JP2002542174A (pt) |
KR (1) | KR20020007371A (pt) |
CN (1) | CN100376288C (pt) |
AU (2) | AUPP977899A0 (pt) |
BR (1) | BR0009712A (pt) |
CA (1) | CA2370296A1 (pt) |
HK (1) | HK1046249A1 (pt) |
NZ (1) | NZ514975A (pt) |
WO (1) | WO2000062657A2 (pt) |
ZA (1) | ZA200108451B (pt) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020086000A1 (en) * | 1999-04-15 | 2002-07-04 | Richard Boyd | Stimulation of thymus for vaccination development |
US20040258672A1 (en) * | 1999-04-15 | 2004-12-23 | Monash University | Graft acceptance through manipulation of thymic regeneration |
AUPR074500A0 (en) * | 2000-10-13 | 2000-11-09 | Monash University | Treatment of t cell disorders |
US20020071829A1 (en) * | 1999-04-15 | 2002-06-13 | Richard Boyd | Normalization of defective T cell responsiveness through manipulation of thymic regeneration |
AU2001295270B2 (en) * | 2000-10-13 | 2007-08-09 | Norwood Immunology Ltd | Treatment of T cell disorders |
AU2002216323C1 (en) * | 2000-10-13 | 2008-05-29 | Norwood Immunology Ltd | Disease prevention by reactivation of the thymus |
WO2002030256A2 (en) * | 2000-10-13 | 2002-04-18 | Monash University | Diagnostic indicator of thymic function |
IL155413A0 (en) * | 2000-10-13 | 2003-11-23 | Univ Monash | Hematopoietic stem cell gene therapy |
AU2002225245C1 (en) * | 2000-10-13 | 2008-07-17 | Norwood Immunology Ltd | Improvement of graft acceptance through manipulation of thymic regeneration |
AU2002216320C1 (en) * | 2000-10-13 | 2008-04-03 | Norwood Immunology Ltd | Hematopoietic stem cell gene therapy |
JP2004510795A (ja) * | 2000-10-13 | 2004-04-08 | モナッシュ・ユニバーシティ | 胸腺の再生を操作することによる移植片受容の改善 |
IL155414A0 (en) * | 2000-10-13 | 2003-11-23 | Univ Monash | Disease prevention by reactivation of the thymus |
IL147138A0 (en) * | 2001-12-17 | 2002-08-14 | Yeda Res & Dev | Methods of and pharmaceutical compositions for modulating cell adhesion, migration and extravasation |
WO2004103271A2 (en) * | 2003-04-18 | 2004-12-02 | Norwood Immunology, Ltd. | Disease prevention and vaccination prior to thymic reactivations |
CA2699012A1 (en) * | 2007-09-11 | 2009-03-19 | Mondobiotech Laboratories Ag | Use of a peptide as a therapeutic agent |
CA2840424C (en) * | 2011-07-01 | 2022-02-01 | Beckman Coulter, Inc. | Regulatory t cells and methods of identifying, obtaining and using to treat immuno-based disorders |
CN103235135B (zh) * | 2013-04-26 | 2015-02-04 | 史其新 | 一种用于表征外周调节性t细胞抑制活性的特征细胞群的检测方法及其应用 |
AU2017358042A1 (en) * | 2016-11-11 | 2019-05-30 | Longeveron Inc. | Methods of using human mesenchymal stem cells to effect cellular and humoral immunity |
AU2019225151A1 (en) * | 2018-02-23 | 2020-08-20 | Duke University | Cultured thymus tissue transplantation promotes donor-specific tolerance to allogeneic solid organ transplants |
US11819520B2 (en) | 2018-02-23 | 2023-11-21 | Duke University | Cultured thymus tissue transplantation promotes donor-specific tolerance to allogeneic solid organ transplants |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH01500663A (ja) * | 1986-08-18 | 1989-03-09 | バンジ・(オーストラリア)・プロプライアタリー・リミテッド | 動物の生殖機能の調節 |
AU634379B2 (en) * | 1991-04-29 | 1993-02-18 | Csl Limited | Recombinant immunocastration vaccine |
-
1999
- 1999-04-15 AU AUPP9778A patent/AUPP977899A0/en not_active Abandoned
-
2000
- 2000-04-17 EP EP00916705A patent/EP1191975A4/en not_active Withdrawn
- 2000-04-17 CA CA002370296A patent/CA2370296A1/en not_active Abandoned
- 2000-04-17 KR KR1020017013148A patent/KR20020007371A/ko not_active Application Discontinuation
- 2000-04-17 BR BR0009712-8A patent/BR0009712A/pt not_active Application Discontinuation
- 2000-04-17 WO PCT/AU2000/000329 patent/WO2000062657A2/en not_active Application Discontinuation
- 2000-04-17 AU AU37977/00A patent/AU779067B2/en not_active Ceased
- 2000-04-17 CN CNB008089663A patent/CN100376288C/zh not_active Expired - Fee Related
- 2000-04-17 JP JP2000611797A patent/JP2002542174A/ja active Pending
- 2000-04-17 NZ NZ514975A patent/NZ514975A/xx unknown
-
2001
- 2001-10-15 ZA ZA200108451A patent/ZA200108451B/en unknown
-
2002
- 2002-09-30 HK HK02107213.4A patent/HK1046249A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
EP1191975A4 (en) | 2005-05-25 |
HK1046249A1 (zh) | 2003-01-03 |
WO2000062657A2 (en) | 2000-10-26 |
AU779067B2 (en) | 2005-01-06 |
WO2000062657A3 (en) | 2001-01-11 |
CA2370296A1 (en) | 2000-10-26 |
CN1364093A (zh) | 2002-08-14 |
EP1191975A2 (en) | 2002-04-03 |
KR20020007371A (ko) | 2002-01-26 |
NZ514975A (en) | 2004-03-26 |
AUPP977899A0 (en) | 1999-05-13 |
JP2002542174A (ja) | 2002-12-10 |
CN100376288C (zh) | 2008-03-26 |
AU3797700A (en) | 2000-11-02 |
ZA200108451B (en) | 2003-01-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25A | Requested transfer of rights approved |
Owner name: NORWOOD IMMUNOLOGY LTD. (AU) Free format text: TRANSFERIDO DE: MONASH UNIVERSITY |
|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8, 11 24 E 25 DA LPI |
|
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |
|
B15K | Others concerning applications: alteration of classification |
Ipc: A61K 38/09 (2006.01), A61P 37/06 (2006.01), A61P 3 |