BG98523A - Hla-limited cytotoxic t-lymphocytic (ctl) epitopes of the virus of hepatite b - Google Patents
Hla-limited cytotoxic t-lymphocytic (ctl) epitopes of the virus of hepatite bInfo
- Publication number
- BG98523A BG98523A BG98523A BG9852394A BG98523A BG 98523 A BG98523 A BG 98523A BG 98523 A BG98523 A BG 98523A BG 9852394 A BG9852394 A BG 9852394A BG 98523 A BG98523 A BG 98523A
- Authority
- BG
- Bulgaria
- Prior art keywords
- virus
- hepatite
- ctl
- hla
- lymphocytic
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title abstract 2
- 231100000433 cytotoxic Toxicity 0.000 title abstract 2
- 230000001472 cytotoxic effect Effects 0.000 title abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 208000006454 hepatitis Diseases 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- 108090001074 Nucleocapsid Proteins Proteins 0.000 abstract 1
- 208000037581 Persistent Infection Diseases 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 231100000283 hepatitis Toxicity 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US74956891A | 1991-08-26 | 1991-08-26 | |
US82768292A | 1992-01-29 | 1992-01-29 | |
US87449192A | 1992-04-27 | 1992-04-27 | |
PCT/US1992/007218 WO1993003764A1 (en) | 1991-08-26 | 1992-08-26 | Hla-restricted hepatitis b virus ctl epitopes |
Publications (1)
Publication Number | Publication Date |
---|---|
BG98523A true BG98523A (en) | 1995-05-31 |
Family
ID=27419385
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG98523A BG98523A (en) | 1991-08-26 | 1994-02-22 | Hla-limited cytotoxic t-lymphocytic (ctl) epitopes of the virus of hepatite b |
Country Status (16)
Country | Link |
---|---|
EP (2) | EP0534615B1 (sv) |
JP (2) | JP3738395B2 (sv) |
AU (1) | AU687725B2 (sv) |
BG (1) | BG98523A (sv) |
CA (1) | CA2115839C (sv) |
CZ (1) | CZ42794A3 (sv) |
DE (1) | DE69231621T2 (sv) |
ES (1) | ES2155060T3 (sv) |
FI (1) | FI940918A (sv) |
GR (1) | GR3035575T3 (sv) |
HU (1) | HUT68510A (sv) |
IL (1) | IL102964A0 (sv) |
NO (1) | NO940660L (sv) |
NZ (2) | NZ244103A (sv) |
OA (1) | OA09888A (sv) |
WO (1) | WO1993003764A1 (sv) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5780036A (en) * | 1991-08-26 | 1998-07-14 | The Scripps Research Institute | Peptides for inducing cytotoxic T lymphocyte responses to hepattis B virus |
US6419931B1 (en) * | 1991-08-26 | 2002-07-16 | Epimmune Inc. | Compositions and methods for eliciting CTL immunity |
US6322789B1 (en) | 1991-08-26 | 2001-11-27 | Epimmune, Inc. | HLA-restricted hepatitis B virus CTL epitopes |
US6607727B1 (en) | 1991-08-26 | 2003-08-19 | The Scripps Research Institute | Peptides for inducing cytotoxic T lymphocyte responses to hepatitus B virus |
US6689363B1 (en) | 1992-01-29 | 2004-02-10 | Epimmune Inc. | Inducing cellular immune responses to hepatitis B virus using peptide and nucleic acid compositions |
US7252829B1 (en) | 1998-06-17 | 2007-08-07 | Idm Pharma, Inc. | HLA binding peptides and their uses |
US7611713B2 (en) | 1993-03-05 | 2009-11-03 | Pharmexa Inc. | Inducing cellular immune responses to hepatitis B virus using peptide compositions |
US9340577B2 (en) | 1992-08-07 | 2016-05-17 | Epimmune Inc. | HLA binding motifs and peptides and their uses |
EP1704868A1 (en) * | 1992-08-07 | 2006-09-27 | Pharmexa Inc. | HLA binding peptides and their uses |
US6235288B1 (en) | 1992-08-26 | 2001-05-22 | The Scripps Research Institute | Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus |
US9266930B1 (en) | 1993-03-05 | 2016-02-23 | Epimmune Inc. | Inducing cellular immune responses to Plasmodium falciparum using peptide and nucleic acid compositions |
US5759551A (en) * | 1993-04-27 | 1998-06-02 | United Biomedical, Inc. | Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines |
DK0708656T3 (da) * | 1993-04-27 | 2002-12-02 | United Biomedical Inc | Antigene LHRH peptidkonstruktioner og universelle syntetiske immunstimulatorer til vacciner |
ATE415173T1 (de) | 1993-09-14 | 2008-12-15 | Pharmexa Inc | Pan dr-bindeproteinen zur erhöhung der immunantwort |
US6413935B1 (en) | 1993-09-14 | 2002-07-02 | Epimmune Inc. | Induction of immune response against desired determinants |
GB9325772D0 (en) * | 1993-12-16 | 1994-02-16 | Smithkline Beecham Biolog | Novel compounds |
US5686068A (en) * | 1994-03-24 | 1997-11-11 | Ludwig Institute For Cancer Research | Isolated peptides derived from MAGE-2, cytolytic T cells specific to complexes of peptide and HLA-A2 molecules, and uses thereof |
JP2001508054A (ja) * | 1996-12-30 | 2001-06-19 | イノジェネティックス・ナムローゼ・フェンノートシャップ | HBsAg由来アネキシンV結合ポリペプチドおよびその使用 |
NZ500287A (en) * | 1997-04-11 | 2002-10-25 | Sangstat Medical Corp | Cytomodulating lipophilic peptides for modulating immune system activity and inhibiting inflammation |
US20010019714A1 (en) * | 1998-04-07 | 2001-09-06 | Charles D. Y. Sia | Hiv-specific cytotoxic t-cell responses |
US7105164B1 (en) | 1998-04-07 | 2006-09-12 | Sanofi Pasteur Limited | HIV-specific cytotoxic T-cell responses |
CU22871A1 (es) | 1998-12-02 | 2003-10-21 | Ct Ingenieria Genetica Biotech | Formulaciones conteniendo partículas semejantes a virus como inmunopotenciadores por vía mucosal |
EP2177534A3 (en) | 1999-11-18 | 2010-07-14 | Pharmexa Inc. | Heteroclitic analogs of class i epitopes |
US7026443B1 (en) | 1999-12-10 | 2006-04-11 | Epimmune Inc. | Inducing cellular immune responses to human Papillomavirus using peptide and nucleic acid compositions |
US7462354B2 (en) | 1999-12-28 | 2008-12-09 | Pharmexa Inc. | Method and system for optimizing minigenes and peptides encoded thereby |
WO2005108416A2 (en) * | 2004-04-21 | 2005-11-17 | The University Of Chicago | Myosin light chain kinase inhibitors and their use |
CA2660830A1 (en) * | 2006-08-14 | 2008-02-21 | Gideon Goldstein | Compositions and methods for the treatment and prophylaxis of multiple strains and subtypes of hiv-1 |
CN102850435B (zh) | 2006-10-17 | 2016-02-17 | 肿瘤疗法科学股份有限公司 | 用于表达mphosph1或depdc1多肽的癌症的肽疫苗 |
US8877206B2 (en) | 2007-03-22 | 2014-11-04 | Pds Biotechnology Corporation | Stimulation of an immune response by cationic lipids |
RU2530555C2 (ru) | 2008-04-17 | 2014-10-10 | ПиДиЭс БАЙОТЕКНОЛОДЖИ КОРПОРЭЙШН | Стимуляция иммунного ответа энантиомерами катионных липидов |
WO2010086294A2 (en) | 2009-01-28 | 2010-08-05 | Epimmune Inc. | Pan-dr binding polypeptides and uses thereof |
CN102573903B (zh) | 2009-08-07 | 2015-12-02 | 特兰斯吉恩股份有限公司 | 用于治疗hbv感染的组合物 |
US10076570B2 (en) | 2009-08-07 | 2018-09-18 | Transgene S.A. | Composition for treating HBV infection |
TWI623618B (zh) | 2011-07-12 | 2018-05-11 | 傳斯堅公司 | Hbv聚合酶突變體 |
US9458447B2 (en) | 2011-08-12 | 2016-10-04 | Oncotherapy Science, Inc. | MPHOSPH1 peptides and vaccines including the same |
WO2013036201A1 (en) * | 2011-09-06 | 2013-03-14 | Agency For Science, Technology And Research | Polypeptide vaccine |
CN105101991A (zh) | 2012-09-21 | 2015-11-25 | Pds生物科技公司 | 改进的疫苗组合物和使用方法 |
CA2840937A1 (en) * | 2013-02-05 | 2014-08-05 | Nitto Denko Corporation | Vaccine composition for transdermal administration |
US20140234377A1 (en) * | 2013-02-05 | 2014-08-21 | Nitto Denko Corporation | Vaccine composition for mucosal administration |
IL257335B (en) | 2015-08-12 | 2022-08-01 | Oncotherapy Science Inc | A depdc1-derived peptide and a component containing it |
US10835600B2 (en) * | 2015-09-08 | 2020-11-17 | Universität Zürich | Compositions against cat allergy |
JP6857909B2 (ja) | 2015-10-08 | 2021-04-14 | オンコセラピー・サイエンス株式会社 | Mphosph1由来ペプチドおよびそれを含むワクチン |
CA3005251A1 (en) | 2015-11-13 | 2017-05-18 | Pds Biotechnology Corporation | Lipids as synthetic vectors to enhance antigen processing and presentation ex-vivo in dendritic cell therapy |
EP3522920A2 (en) | 2016-10-10 | 2019-08-14 | Transgene SA | Immunotherapeutic product and mdsc modulator combination therapy |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4935235A (en) * | 1979-05-24 | 1990-06-19 | The Regents Of The University Of California | Non-passageable viruses |
US5017558A (en) * | 1980-01-14 | 1991-05-21 | The Regents Of The University Of California | Synthetic vaccine peptide epitomes of hepatitis B surface antigen |
JPS60161999A (ja) * | 1984-02-02 | 1985-08-23 | Chemo Sero Therapeut Res Inst | ペプチド |
US4818527A (en) * | 1986-12-09 | 1989-04-04 | Scripps Clinic And Research Foundation | T cell epitopes of the hepatitis B virus nucleocapsid protein |
US4882145A (en) * | 1986-12-09 | 1989-11-21 | Scripps Clinic And Research Foundation | T cell epitopes of the hepatitis B virus nucleocapsid protein |
EP0420913B1 (en) * | 1988-06-14 | 1995-11-15 | Cell Med, Inc. | Heterofunctional cellular immunological reagents, vaccines containing same and methods for the use of same |
IT1238343B (it) * | 1989-10-16 | 1993-07-13 | Cesalpino Andrea Fond | Procedimento per la preparazione di vaccini capaci di generare non solo la risposta immune dei linfociti t helper,ma anche un'efficace risposta di linfociti t citotossici,e vaccini con queste caratteristiche |
US5480967A (en) * | 1990-01-05 | 1996-01-02 | United Biomedical, Inc. | HIV-1 core protein fragments |
-
1992
- 1992-08-26 EP EP92307764A patent/EP0534615B1/en not_active Expired - Lifetime
- 1992-08-26 CZ CS94427A patent/CZ42794A3/cs unknown
- 1992-08-26 WO PCT/US1992/007218 patent/WO1993003764A1/en not_active Application Discontinuation
- 1992-08-26 JP JP50466493A patent/JP3738395B2/ja not_active Expired - Lifetime
- 1992-08-26 IL IL102964A patent/IL102964A0/xx unknown
- 1992-08-26 EP EP00102538A patent/EP1018344A3/en not_active Withdrawn
- 1992-08-26 CA CA2115839A patent/CA2115839C/en not_active Expired - Lifetime
- 1992-08-26 HU HU9400581A patent/HUT68510A/hu unknown
- 1992-08-26 DE DE69231621T patent/DE69231621T2/de not_active Expired - Lifetime
- 1992-08-26 NZ NZ244103A patent/NZ244103A/en unknown
- 1992-08-26 AU AU25487/92A patent/AU687725B2/en not_active Ceased
- 1992-08-26 NZ NZ270605A patent/NZ270605A/en not_active IP Right Cessation
- 1992-08-26 ES ES92307764T patent/ES2155060T3/es not_active Expired - Lifetime
-
1994
- 1994-02-22 BG BG98523A patent/BG98523A/xx unknown
- 1994-02-25 NO NO940660A patent/NO940660L/no unknown
- 1994-02-25 OA OA60475A patent/OA09888A/en unknown
- 1994-02-25 FI FI940918A patent/FI940918A/sv not_active Application Discontinuation
-
2001
- 2001-03-14 GR GR20010400422T patent/GR3035575T3/el unknown
-
2003
- 2003-11-20 JP JP2003391442A patent/JP3586278B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
NZ270605A (en) | 1997-07-27 |
CA2115839C (en) | 2010-06-01 |
DE69231621D1 (de) | 2001-02-08 |
JP3738395B2 (ja) | 2006-01-25 |
EP1018344A3 (en) | 2000-09-20 |
HU9400581D0 (en) | 1994-05-30 |
EP1018344A2 (en) | 2000-07-12 |
EP0534615A2 (en) | 1993-03-31 |
AU2548792A (en) | 1993-03-16 |
NO940660L (no) | 1994-04-22 |
JP3586278B2 (ja) | 2004-11-10 |
WO1993003764A1 (en) | 1993-03-04 |
JP2004075693A (ja) | 2004-03-11 |
NO940660D0 (no) | 1994-02-25 |
FI940918A (sv) | 1994-04-08 |
IL102964A0 (en) | 1993-01-31 |
FI940918A0 (sv) | 1994-02-25 |
CA2115839A1 (en) | 1993-03-04 |
ES2155060T3 (es) | 2001-05-01 |
OA09888A (en) | 1994-09-15 |
HUT68510A (en) | 1995-06-28 |
NZ244103A (en) | 1997-07-27 |
CZ42794A3 (en) | 1994-11-16 |
JPH06510051A (ja) | 1994-11-10 |
GR3035575T3 (en) | 2001-06-29 |
EP0534615B1 (en) | 2001-01-03 |
EP0534615A3 (en) | 1994-05-25 |
DE69231621T2 (de) | 2001-05-31 |
AU687725B2 (en) | 1998-03-05 |
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