BG4460U1 - Dietary supplement of medicinal plants beneficial in heart failure conditions - Google Patents

Abstract

The dietary supplement of medicinal plants beneficial in heart failure conditions according to the present utility model contains only de-hydrolyzed bioactive extracts, packaged in cellulose capsules, that are easily accepted and assimilated in the body. Said dietary supplement does not contain additional fillers, preservatives or artificial dyestuffs. The ten medicinal plants included in the dietary supplement and the weight ratios between them have been selected in a precise manner, having regard to their chemical composition, effects and known uses, as well as to the strong synergies derived when these plants are combined. In the combination proposed according to the present utility model, the dry extracts of medicinal plants interact coherently to improve the functioning of the cardiovascular system, support the evacuation of water built up in the limbs and abdomen through intensified diuresis, normalize the muscular functions, and produce soothing effect.

Description

(54) DIETARY SUPPLEMENT FROM MEDICINAL PLANTS IN HEART FAILURE

Field of technique

The utility model relates to a dietary supplement of medicinal plants that is suitable for taking by individuals with heart failure, valvular disease, angina pectoris, atherosclerosis of the coronary arteries and cardiac neurosis.

Prior art

Heart failure is a serious medical condition in which the heart does not pump enough blood for the body's needs. As a result, the blood cannot deliver the necessary oxygen and nutrients to all parts of the body and transport waste products from many organs to the lungs and kidneys, where they are eliminated or excreted. Heart failure usually causes muscle fatigue/weakness, water accumulation in the lungs, limbs and abdomen, shortness of breath, rapid heartbeat, increased blood pressure, neuropsychiatric disorders.

In addition to the many drugs for the treatment of heart failure distributed in the pharmacy network, many nutritional supplements and herbal compositions are also known that support heart activity and are suitable for taking by persons with heart failure.

From patent US 11,077,162 B2, a heart-protecting herbal preparation for preventing and ameliorating coronary heart disease is known, which includes an ethanolic extract of roots, leaves, stems, flowers and seeds of 21 different plants used in Chinese traditional medicine.

Bulgarian folk medicine uses a number of medicinal plants that support the heart, help maintain healthy blood pressure levels and have a calming effect on the nervous system. Currently, in specialized herbal shops and pharmacies in the country, herbal mixtures and nutritional supplements are available, including combinations of different medicinal plants, suitable for taking in heart problems.

A herbal mixture prepared according to the recipe of the folk healer Petar Dimkov is offered for the treatment of hypertension. The known composition includes eight medicinal plants in the following weight % of the drug: mint (Mentha) 20%; white mistletoe (Viscum album) 15%; lemon balm (Melissa cjicinalis) 15%; Communiga (Melilotus Officinalis) 10%; willow leaves (Salix alba) 10%; horsetail (Equisetum arvense) 10%; hawthorn flower (Crataegus monogyna) 10% and rosehip (Fumaria officinalis) 10%. The composition is taken in the form of a decoction. To prepare the decoction, soak 2 tablespoons of the herbal mixture in 500 g of boiling water for 10 minutes, then filter the decoction. Drink 100 g 3 times a day before meals.

For the treatment of heart failure, an herbal mixture is offered, including: 100 g of hawthorn flowers; 50 g of blood geranium rhizomes; 50 g of nettle roots; 30 g of lemon balm stalks; 30 g lavender flowers; 20 g of lily of the valley leaves and 40 g of Icelandic lichen. The composition is taken in the form of a decoction. To prepare the decoction, 2 tablespoons of the herbs are boiled for 2 minutes in 400 ml of water. After the liquid has cooled, it is filtered and drunk 1 glass of wine before meals 3 times a day.

For the treatment of atherosclerosis and myocardiosclerosis, a herbal mixture is offered, including: 200 g of horsetail stalks; 20 g of hawthorn flowers; 20 g of dilliana roots; 20 g of white mistletoe stalks; 20 g lavender flowers; 20 g of lemon balm leaves; 20 g of birch leaves; 20 g of whip stalks; 20 g stalks of blue gentian and 20 g stalks of wild flower. The composition is taken in the form of a decoction. To prepare the decoction, boil 1 tablespoon of horsetail stalks for 10 minutes in 0.5 l of water. Then add one tablespoon of the pre-mixed remaining herbs. Let it soak for 1 hour. Strain the decoction and drink 1 glass of wine 4 times a day, before meals.

From the description of a useful model BG 3186 U1 is a known dietary supplement to improve heart function, which is used in heart failure and improves the pumping function of the left ventricle of the heart. It is a capsule including ribose 360 mg, creatine 360 mg, co-enzyme Q-10 - 30 mg and vitamin E - 2 mg, and the ingredients are in powder form. Take from 1 to 9 capsules, three times a day, half an hour before meals.

Also known is the nutritional supplement "Cardio Formula", a tincture that is a combination of herbal extracts designed to support the heart, help maintain healthy blood pressure levels and have a calming effect on the nervous system. It contains alcoholic extracts of the following medicinal plants: roots of blood geranium (Geranium sanguineum); hawthorn (Crataegus monogyna); lemon balm (Melissa Officinalis), thyme (Thymus vulgaris); Allium ursinum (Allium ursinum); corn cob (Stigmata maydis) and common nettle (Urtica dioica). Take 40 drops, dissolved in 50 ml of water or juice, 2-3 times a day, before meals.

From the foregoing, it can be seen that various herbal mixtures as well as nutritional supplements comprising combinations of phytoextracts or other components are known to improve cardiac function. Known herbal mixtures consist only of medicinal plants, but preparing a decoction from them daily takes time and causes inconvenience to those taking them, especially since the finished decoction should usually be taken three times a day. The two famous nutritional supplements also make it difficult for those who take them, because they must be taken three times a day and the time and method of taking them must be taken into account (capsules are taken half an hour before meals, and the drops are dissolved in water or juice).

Technical nature of the utility model

The task of the useful model is to create a food supplement from medicinal plants, with rapid absorption by the body, easy and convenient to use, which improves the cardiac activity of persons with heart failure, valvular defects, angina pectoris, atherosclerosis of the coronary arteries and cardiac neurosis .

The task is solved by a nutritional supplement of medicinal plants for heart failure, containing extracts of the roots of blood geranium (Geranium sanguineum), common hawthorn (Crataegus monogyna) and common nettle (Urtica dioica). According to the useful model, the extract of common hawthorn (Crataegus monogyna) is from its flowers, and the extract of common nettle (Urtica dioica) is from its rhizomes. willow (Salix alba), rosehip berries (Cynosbati), lazarine stalks (Asperula odorata), medicinal whip stalks (Agrimonia eupatoria), valerian rhizomes (Valeriana ojficinalis) and comfrey roots (Inula helenium). In addition, all extracts are dry, placed in a cellulose capsule and are in the following amounts (in mg):

- flowers of common hawthorn (Crataegus monogyna) 32 - 38;

- stalks of horsetail (Equisetum arvense) 32 - 38;

- roots of blood geranium (Geranium sanguineum) 32 - 38;

- rhizomes of common nettle (Urtica dioica) 32 - 38;

- white willow bark (Salix alba) 17 - 23;

- rosehip fruits (Cynosbati) 17 - 23;

- stalks of lazarkina (Asperula odorata) 14 - 20;

- stalks of medicinal whip (Agrimonia eupatoria) 14 - 20;

- rhizomes of valerian (Valeriana officinalis) 14 - 20;

- roots of white comfrey (Inula helenium) 14 - 20.

In a preferred embodiment of the utility model, the nutritional supplement of medicinal plants for heart failure, the total content of dry extracts of medicinal plants in the capsule is 250 mg, such as the flowers of common hawthorn (Crataegus monogyna), the stalks of field horsetail (Equisetum arvense), the roots of blood geranium (Geranium sanguineum) and common nettle rhizomes (Urtica dioica) are 35 mg each, white willow bark (Salix alba) and rosehip berries (Cynosbati) are 20 mg each, and lazarine stalks (Asperula odorata), stalks of medicinal whip (Agrimonia eupatoria), the rhizomes of valerian (Valeriana officinalis) and the roots of white comfrey (Inula helenium) are 17.5 mg each.

The extracts of stalks, roots, rhizomes, peels, flowers and fruits of ten medicinal plants included in the food supplement have the following content and effects on the human body.

Hawthorn flowers (Crataegus monogyna) contain over 15 flavonoid compounds, biogenic amines, triterpenes, quercetin, C-glycosides, essential oil, etc. Common hawthorn has a cardiotonic, vasodilator, lowering arterial pressure and sedative (calming) effect. Hawthorn flower extract improves the activity of the heart muscle, slows down heart activity and regulates abnormal heart rhythms, improves sleep and lowers blood cholesterol.

Horsetail stalks (Equisetum arvense) contain flavonoids, caffeic acid esters, salicylic acid, pyridine alkaloids, vitamins A and C, etc. Horsetail has astringent, diuretic, anti-inflammatory and antispasmodic effects. Horsetail stalk extract increases the normal tone, elasticity and permeability of blood vessels, lowers blood pressure, reduces uric acid in the blood, has a beneficial effect on kidney function and strengthens the immune system.

The roots of blood geranium (Geranium sanguineum) include a large amount of tannins, essential oils, organic acids, vitamin C, etc. It has mainly hemostatic, astringent, antiviral and anti-inflammatory effects, which are due to tannins. The extract from the roots of the blood geranium has a hematopoietic effect, strengthens the immune system, lowers blood pressure, acts as a sedative and improves sleep.

The rhizomes of common nettle (Urtica dioica) contain histamine, serotonin, flavonoids, carotene, essential oil, vitamin C, potassium, calcium, etc. They have anti-inflammatory, pain-relieving, hemostatic, hematopoietic, anti-allergic and diuretic effects. By taking an extract from the rhizomes of common nettle, the hematopoietic function of the body is improved, the feeling of fatigue, exhaustion and weakness is overcome, the body is toned and invigorated. In addition, it improves the function of the kidneys, acts as a herbal diuretic and helps to release the water accumulated in the body due to heart failure.

White willow bark (Salix alba) contains glucosides and esters, salicylic acid, tannins, flavonoids, etc. They have anti-rheumatic, anti-inflammatory, analgesic and strong antiviral effects. White willow bark is a source of salicin, which is a natural means of reducing the risk of developing cardiovascular disease. White willow bark extract reduces thrombus formation and minimizes the possibility of clogging blood vessels, reduces uric acid and contributes to normal muscle function.

Rosehip fruits (Cynosbati) contain tocopherol, flavonoids, tannins, essential oils, fruit acids, pectin, vitamins C, B, K and P, etc. They have antispasmodic, antibacterial, caustic, hemostatic and diuretic effects. Rosehip fruit extract enhances the formation of red blood cells, increases physical performance, improves digestion, lowers blood sugar. Thanks to its mineral composition, in particular the content of vitamin P, rose hips strengthen blood vessels and lower cholesterol levels.

The stalks of lazarquina (Asperula odorata) contain glucosides - asperuloside, coumarin, tannins, essential oils, vitamin C, etc. They have antispasmodic, antimicrobial, pain-relieving, lymphokinetic and anti-edema effect. The extract of lazarkina stalks tones the heart activity, relaxes the smooth muscles, increases diuresis and acts as a sedative in cardiac neurosis.

The stalks of medicinal whip (Agrimonia eupatoria) contain catechin tannins, essential oil, flavonoids, silicates, vitamins K, P and C, nicotinic acid, etc. They are astringent, antibacterial, anti-inflammatory, hemostatic, caustic and diuretic. The extract from the stems of the medicinal whip increases diuresis and has a well-expressed capillarotonic effect due to vitamins P and C.

The rhizomes of valerian (Valeriana officinalis) contain iridoids, essential oils, alkaloids, resins, tannins, tannins, sugars, etc. They have an antidepressant, sedative, antispasmodic and muscle relaxant effect. The extract from the roots of the medicinal dilanka normalizes the heart rhythm, lowers blood pressure, calms and improves sleep.

Inula helenium roots contain essential oil, sesquiterpene lactones, inulin, triterpenes, etc. They have antibacterial, anti-inflammatory, mucolytic, anthelmintic and antitumor effects. Wormwood root extract relieves muscle spasms and tension, soothes the bronchial passages, and is a nourishing agent that helps reduce chronic bronchial secretions.

The advantage of the herbal supplement for heart failure, according to the utility model, is that it is completely plant-based. It is a cellulose capsule containing only dehydrolyzed biologically active plant extracts that are easily accepted and absorbed by the body. The supplement does not contain additional fillers, preservatives and artificial colors. In addition, it is easy and convenient to take, as it is taken once, 1 or 2 capsules per day.

The selection of the medicinal plants described above, used in the dietary supplement for heart failure, has been made precisely, both on the basis of their chemical compositions, actions and known applications, and on the highly pronounced synergistic effect of their combination. The dry extracts of medicinal plants in the proposed combination act interrelatedly, improving the activity of the cardiovascular system, supporting the release of accumulated water in the limbs and abdomen, through intensified diuresis, normalizing the work of the muscles and having a sedative effect.

The effect of taking the food supplement from medicinal plants in heart failure is confirmed by the clinical studies. Women and men with a verified diagnosis of heart failure and valvular defects participate in them. The participants in the clinical studies, during the period of taking the nutritional supplement, continued to take the drugs prescribed by their cardiologists without changing their doses or type. It is found that after taking 1-2 capsules per day of the nutritional supplement described in the below presented example of the implementation of the useful model, for a period of 3 to 12 months, an improvement in the functional state of 93% of those who participated in the research was found persons, resulting in a reduction of clinical pathological symptoms. A decrease in physical weakness and an increase in physical activity were observed in 93% of individuals. In 90% of individuals, complete control of pain in the heart area and reduction of cardiac dyspnea is observed. In 68%, complete compensation of the arrhythmia was observed, and in 22%, a reduction in the frequency and intensity of the arrhythmia was observed.

It is important to note that no gastrointestinal complaints (such as nausea, vomiting, constipation or diarrhea) or allergic reactions were observed during the period of taking the food supplement.

Example implementation of the utility model

According to an exemplary embodiment of the utility model, the nutritional supplement of medicinal plants in heart failure is a cellulose capsule of 250 mg containing dry extracts of the following components, in the respective amounts in (mg):

- flowers of common hawthorn (Crataegus monogyna) 35;

- stalks of horsetail (Equisetum arvense) 35;

- roots of blood geranium (Geranium sahguineum) 35;

- rhizomes of common nettle (Urtica dioica) 35;

- bark of white willow (Salix alba) 20;

- rosehip fruits (Cynosbati) 20;

- stalks of lazarkin (Asperula odorata) 17.5;

- stalks of medicinal whip (Agrimonia eupatoria) 17.5;

- rhizomes of valerian (Valeriana cjficinalis) 17.5;

- roots of white comfrey (Inula helenium) 17.5.

The way to prepare the nutritional supplement from medicinal plants for heart failure is by using commonly known methods, including the following stages: mixing the indicated parts of the ten medicinal plants according to a recipe, according to the weight ratios between them in the final product; obtaining an aqueous extract from the mixture by boiling; vacuum extraction of the aqueous extract to obtain a dry extract; sealing in a cellulose capsule 250 mg of dry extract and packaging the capsules.

Claims (1)

Food supplement of medicinal plants for heart failure containing extracts of the roots of blood geranium (Geranium sanguineum), common hawthorn (Crataegus monogyna) and common nettle (Urtica dioica), characterized in that the extract of common hawthorn (Crataegus monogyna) is from the flowers, the extract of common nettle (Urtica dioica) is from the rhizomes, and additionally contains extracts of: horsetail stalks (Equisetum arvense), white willow bark (Salix alba), rosehip berries (Cynosbati), lazarine stalks (Asperula odorata), stalks of medicinal whip (Agrimonia eupatoria), rhizomes of medicinal valerian (Valeriana officinalis) and roots of white comfrey (Inula helenium), and all extracts are dry, placed in a cellulose capsule and are in the following amounts (in mg): - flowers of common hawthorn (Crataegus monogyna) 32 - 38; - stalks of horsetail (Equisetum arvense) 32 - 38; - roots of blood geranium (Geranium sanguineum) 32 - 38; - rhizomes of common nettle (Urtica dioica) 32 - 38; - white willow bark (Salix alba) 17 - 23; - rosehip fruits (Cynosbati) 17 - 23; - stalks of lazarkina (Asperula odorata) 14 - 20; - stalks of medicinal whip (Agrimonia eupatoria) 14 - 20; - rhizomes of valerian (Valeriana officinalis) 14 - 20; - roots of white comfrey (Inula helenium) 14 - 20