BG20348A3 - Метод за получаване на 4-субституирани 1-(4,4-диарил-бутил) пиперидини - Google Patents

Метод за получаване на 4-субституирани 1-(4,4-диарил-бутил) пиперидини

Info

Publication number
BG20348A3
BG20348A3 BG021601A BG2160172A BG20348A3 BG 20348 A3 BG20348 A3 BG 20348A3 BG 021601 A BG021601 A BG 021601A BG 2160172 A BG2160172 A BG 2160172A BG 20348 A3 BG20348 A3 BG 20348A3
Authority
BG
Bulgaria
Prior art keywords
piperidines
diaryl
butyl
substituted
preparation
Prior art date
Application number
BG021601A
Other languages
English (en)
Inventor
Marcel Janssen
Henri Dhaen
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of BG20348A3 publication Critical patent/BG20348A3/bg

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • C07D307/33Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/64Acyl halides
    • C07C57/72Acyl halides containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/52Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
BG021601A 1971-11-25 1972-10-12 Метод за получаване на 4-субституирани 1-(4,4-диарил-бутил) пиперидини BG20348A3 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9485771A JPS5527915B2 (bg) 1971-11-25 1971-11-25

Publications (1)

Publication Number Publication Date
BG20348A3 true BG20348A3 (bg) 1975-11-05

Family

ID=14121686

Family Applications (2)

Application Number Title Priority Date Filing Date
BG024007A BG20349A3 (bg) 1971-11-25 1972-10-12 Метод за получаване на 1(4,4-бис (р-флуор-фенил) бутил)-4-пиперидил) -2- бензимидазолинон
BG021601A BG20348A3 (bg) 1971-11-25 1972-10-12 Метод за получаване на 4-субституирани 1-(4,4-диарил-бутил) пиперидини

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BG024007A BG20349A3 (bg) 1971-11-25 1972-10-12 Метод за получаване на 1(4,4-бис (р-флуор-фенил) бутил)-4-пиперидил) -2- бензимидазолинон

Country Status (14)

Country Link
JP (1) JPS5527915B2 (bg)
AR (2) AR198393A1 (bg)
BG (2) BG20349A3 (bg)
CA (1) CA983503A (bg)
CH (1) CH579048A5 (bg)
CS (1) CS168014B2 (bg)
ES (1) ES408926A1 (bg)
FR (1) FR2161007A1 (bg)
HU (1) HU165208B (bg)
IL (1) IL40917A (bg)
NL (1) NL7214913A (bg)
RO (2) RO63063A (bg)
SU (1) SU462333A3 (bg)
YU (1) YU35120B (bg)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4082755A (en) * 1977-02-14 1978-04-04 Janssen Pharmaceutica N.V. 1-[(Diarylmethyl)aminoalkyl]piperidimes
CN106187863A (zh) * 2016-07-15 2016-12-07 湖南中南制药有限责任公司 五氟利多的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE633495A (bg) * 1962-06-13

Also Published As

Publication number Publication date
FR2161007B1 (bg) 1976-03-05
HU165208B (bg) 1974-07-27
AR199497A1 (es) 1974-09-09
ES408926A1 (es) 1976-03-01
IL40917A (en) 1976-10-31
CH579048A5 (bg) 1976-08-31
RO63063A (fr) 1978-07-15
SU462333A3 (ru) 1975-02-28
BG20349A3 (bg) 1975-11-05
AR198393A1 (es) 1974-06-21
YU35120B (en) 1980-09-25
CA983503A (en) 1976-02-10
YU291672A (en) 1980-03-15
IL40917A0 (en) 1973-01-30
JPS4860092A (bg) 1973-08-23
CS168014B2 (bg) 1976-05-28
FR2161007A1 (en) 1973-07-06
JPS5527915B2 (bg) 1980-07-24
RO62760A (fr) 1978-02-15
NL7214913A (bg) 1973-05-29

Similar Documents

Publication Publication Date Title
BG20353A3 (bg) Метод за получаване на несиметрични 1,4-дихидропиридини
NO144568C (no) Analogifremgangsmaate til fremstilling av 3-substituerte 4-fenylpiperidiner
BG20813A3 (bg) Метод за получаване на заместени бензилпеницилини
BG21027A3 (bg) Метод за получаване на изотиоцианобензазоли
FI55194B (fi) Foerfarande foer framstaellning av 6-substituerade 4-amino-1,2-dihydro-1-hydroxi-2-iminopyrimidiner
BG19376A3 (bg) Метод за получаване на заместени бензилпеницилин
BG26526A3 (bg) Метод за получаване на 1-(бензазолилалкил)пиперидинови производни
AR199006A1 (es) Procedimiento para preparar 1,4,5,6-tetrahidropiridinas 3-sustituidas
BG18872A3 (bg) Метод за получаване на 4-амино-1,2,4-триазин-5-они
RO62790A (fr) Procede pour la preparation du 1-(2-benzothyazolil)-1,3-dialkylcarbamides
BG20792A3 (bg) Метод за получаване на /2/ фурил - метил/ 6,7 бензоморфани
SU474150A3 (ru) Способ получени производных окса-1-диаза-3,8-спиро-(4,5)-декана
BG19593A3 (bg) Метод за получаване на субституирани 3-/-2-/4- фенил-1- пиперазини
BG20330A3 (bg) Метод за получаване на 4-(4-бифенилил)-бутаноли
BG20348A3 (bg) Метод за получаване на 4-субституирани 1-(4,4-диарил-бутил) пиперидини
BG18859A3 (bg) Метод за получаване на 1-(2-циано-4-хлорфенокси)- 2-хидрокси-3-(1,1-диметил-2-хидроксилетил)- аминопропан
SE415475B (sv) Forfarande for framstellning av 4,5-didehydro-pgf?711alfa
SU430556A3 (ru) Способ получения полиарилен-1, 3, 4- -оксадиазолов
SE413504B (sv) Forfarande for framstellning av 1-(n-(p-fluorbensoylpropyl)-4-piperidyl)-karbamider
SU499260A1 (ru) Способ получени 4-замещенных 1,2-антрахинонимидазолинов
SE395148B (sv) Sett att framstella 1-((2'-alkyd-4'-aminopyrimidyl-5')-metyl)-pyridinderivat
FI48734C (fi) Tapa valmistaa 3,4-dihydroisokinoliinijohdannaisia.
SU474147A3 (ru) Способ получени 1,2-дигидро-2оксо-4-диалкиламино-пиримидо(4,5- )-хиноксалин-5,10-двуокисей
DK132320C (da) Fremgangsmade til fremstilling af 1,4-dicyanobutener
SU430554A3 (ru) Способ получения производных 2,3-бензоксазепина