BG108153A - Composition of liquid medicamentous form of anti-ulcer effect and method for the production thereof - Google Patents

Abstract

The medicamentous form comprises an active effective substance of aluminium sucrososulphate. The suitably selected auxiliary substances and technological regime for the preparation of the medicamentous form result in the production of suspension with optimum particles sizes of the active substance, even covering of the ulcerous surface and guaranteed microbial purity. The medicamentous form comprises aluminium sucrososulphate as active substance and a mixture of wheat starch and xanthan gum as stabilizer of the suspension, preservative including a combination of sodium benzoate, methyl parahydroxybenzoate and ethyl parahydroxybenzoate, sweetener - saccharine natrium and solvent, mixture of glycerol and treated water, in the following quantitative ratios of the components, in g: aluminium sucrososulphate 20, wheat starch from 1 to 5; xanthan gum from 0.05 to 0.5; sodium benzoate 0.1, methyl parahydroxybenzoate 0.1, propyl parahydroxybenzoate 0.02, saccharine natrium from 0.02 to 1, 30%, simeticon emulsion from 0.1 to 0.5, aromatizer from 0.02 to 0.05, glycerol from 5 to 15 and purified water up to 100 ml. Gel is prepared for producing the form, of xanthan gum, starch glue and concentrated suspension of sucralphate, which are mixed successively, the mixture is homogenized, is ground in a colloid mill and is dosed.