BE906034A - WATER-SOLUBLE PHARMACEUTICAL COMPOSITIONS CONTAINING UBIQUINONE AS ACTIVE INGREDIENT USEFUL IN DIFFERENT THERAPEUTIC APPLICATIONS - Google Patents

WATER-SOLUBLE PHARMACEUTICAL COMPOSITIONS CONTAINING UBIQUINONE AS ACTIVE INGREDIENT USEFUL IN DIFFERENT THERAPEUTIC APPLICATIONS

Info

Publication number
BE906034A
BE906034A BE0/217600A BE217600A BE906034A BE 906034 A BE906034 A BE 906034A BE 0/217600 A BE0/217600 A BE 0/217600A BE 217600 A BE217600 A BE 217600A BE 906034 A BE906034 A BE 906034A
Authority
BE
Belgium
Prior art keywords
water
active ingredient
pharmaceutical compositions
compositions containing
therapeutic applications
Prior art date
Application number
BE0/217600A
Other languages
French (fr)
Inventor
Pierre-Noel Brasey
Original Assignee
Seuref Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seuref Ag filed Critical Seuref Ag
Publication of BE906034A publication Critical patent/BE906034A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Compositions pharmaceutiques aqueuses contenant de l'ubiquinone, un émulsifiant non ionique, un solvant hydroxylé, des agents anti-oxydants et éventuellement du diméthylacétamide. L'administration des compositions selon l'invention par les voies orales, parentérales et topiques sont hydrosolubles et stables, n'entrainant pas de phénomènes de précipitation du principe actif. Leur biodisponibilité améliorée (meilleure absorption du principe actif) entraine une efficacité thérapeutique accrue.Aqueous pharmaceutical compositions containing ubiquinone, a nonionic emulsifier, a hydroxylated solvent, antioxidants and optionally dimethylacetamide. The administration of the compositions according to the invention by the oral, parenteral and topical routes are water-soluble and stable, not causing precipitation phenomena of the active principle. Their improved bioavailability (better absorption of the active ingredient) leads to increased therapeutic efficacy.

BE0/217600A 1985-12-24 1986-12-23 WATER-SOLUBLE PHARMACEUTICAL COMPOSITIONS CONTAINING UBIQUINONE AS ACTIVE INGREDIENT USEFUL IN DIFFERENT THERAPEUTIC APPLICATIONS BE906034A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH5525/85A CH667387A5 (en) 1985-12-24 1985-12-24 UBICHINONE AQUEOUS PHARMACEUTICAL FORMULATIONS.

Publications (1)

Publication Number Publication Date
BE906034A true BE906034A (en) 1987-04-16

Family

ID=4295081

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/217600A BE906034A (en) 1985-12-24 1986-12-23 WATER-SOLUBLE PHARMACEUTICAL COMPOSITIONS CONTAINING UBIQUINONE AS ACTIVE INGREDIENT USEFUL IN DIFFERENT THERAPEUTIC APPLICATIONS

Country Status (7)

Country Link
JP (1) JPS62158209A (en)
BE (1) BE906034A (en)
CH (1) CH667387A5 (en)
DE (1) DE3643330A1 (en)
FR (1) FR2598320B1 (en)
GB (1) GB2184355B (en)
IT (1) IT1198247B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002076433A1 (en) * 2001-03-27 2002-10-03 C.S. Bioscience, Inc. Dental formulation

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1250672B (en) * 1991-07-11 1995-04-21 Idb Holding Spa ORAL FORMULATIONS OF UBIDECARENONE IN AQUEOUS SOLUTION
ES2051643B1 (en) * 1992-10-13 1995-02-16 Inverni Della Beffa Farma ORAL FORMULATIONS OF UBIDECARENONE IN THE FORM OF AQUEOUS SOLUTIONS.
GR1001364B (en) * 1992-10-16 1993-10-29 Inverni Della Beffa Farma Ubidecarenone oral formulations in the form of aqueous solutions.
EP1398026B1 (en) * 1997-02-12 2006-06-21 MSE Pharmazeutika GmbH The use of 2,3-dimethoxy-5-methyl-6-decaprenyl-1,4-benzoquinone in the treatment of incontinence
EP1007018B1 (en) * 1997-02-12 2003-10-08 MSE Pharmazeutika GmbH The use of 2,3-dimethoxy-5-methyl-6-decaprenyl-1,4-benzoquinone in the treatment of tinnitus
US5925335A (en) * 1997-06-12 1999-07-20 C.S. Bioscience Inc. Dental formulation
EP0888774A3 (en) * 1997-06-30 1999-11-10 Soft Gel Technologies, Inc. Soft gel Coenzyme Q10 formulation
US6200550B1 (en) * 1998-12-11 2001-03-13 Q-Pharma, Inc. Oral care compositions comprising coenzyme Q10
DE19944137A1 (en) * 1999-09-15 2001-03-22 Beiersdorf Ag O / W emulsions containing one or more biochinones and increased glycerin content
JP3742602B2 (en) * 2001-05-09 2006-02-08 株式会社カネカ Stable solution of reduced coenzyme Q
WO2005035477A1 (en) * 2003-10-08 2005-04-21 Kaneka Corporation Method of stabilizing compound having quinone skeleton and stabilized composition
JP2008520563A (en) * 2004-11-16 2008-06-19 バイオアバイラビリティ，インク． High concentration self-microemulsifying coenzyme Q10 preparation for nutritional use
JP5722299B2 (en) * 2012-12-07 2015-05-20 バイオアバイラビリティ，インク． High concentration self-microemulsifying coenzyme Q10 preparation for nutritional use
JP5999765B2 (en) * 2012-12-07 2016-09-28 バイオアバイラビリティ，インク． High concentration self-microemulsifying coenzyme Q10 preparation for nutritional use

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1334961A (en) * 1961-03-06 1963-08-16 Merck & Co Inc Stable aqueous solutions based on substituted benzoquinone
NL275602A (en) * 1961-03-06
JPS498246B1 (en) * 1965-07-15 1974-02-25
GB1225979A (en) * 1967-03-23 1971-03-24
GB1317865A (en) * 1971-11-15 1973-05-23 Jujo Paper Co Ltd Biologically active composition
JPS5218811A (en) * 1975-08-01 1977-02-12 Eisai Co Ltd Preparation of aqueous solution of fat- soluble substances
JPS58113127A (en) * 1981-12-28 1983-07-05 Ajinomoto Co Inc Aqueous solution containing ubidecarenone
JPS6025918A (en) * 1983-07-25 1985-02-08 Ajinomoto Co Inc Aqueous solution containing fat-soluble drug

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002076433A1 (en) * 2001-03-27 2002-10-03 C.S. Bioscience, Inc. Dental formulation

Also Published As

Publication number Publication date
GB2184355B (en) 1990-03-28
JPH0455404B2 (en) 1992-09-03
JPS62158209A (en) 1987-07-14
GB2184355A (en) 1987-06-24
DE3643330A1 (en) 1987-06-25
GB8630158D0 (en) 1987-01-28
IT1198247B (en) 1988-12-21
FR2598320A1 (en) 1987-11-13
IT8622844A1 (en) 1988-06-23
FR2598320B1 (en) 1990-11-02
IT8622844A0 (en) 1986-12-23
CH667387A5 (en) 1988-10-14

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: SEUREF A.G.

Effective date: 19931231