BE899542A - Composition associant un aminoglycoside ayant une nephrotoxicite avec un agent inhibiteur de nephrotoxicite. - Google Patents

Composition associant un aminoglycoside ayant une nephrotoxicite avec un agent inhibiteur de nephrotoxicite.

Info

Publication number
BE899542A
BE899542A BE0/212851A BE212851A BE899542A BE 899542 A BE899542 A BE 899542A BE 0/212851 A BE0/212851 A BE 0/212851A BE 212851 A BE212851 A BE 212851A BE 899542 A BE899542 A BE 899542A
Authority
BE
Belgium
Prior art keywords
nephrotoxicity
aminoglycoside
composition combining
inhibitor agent
composition
Prior art date
Application number
BE0/212851A
Other languages
English (en)
Inventor
P D Williams
G H Hottendorf
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of BE899542A publication Critical patent/BE899542A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/29—Polyamino acid or polypeptide with an uninterrupted series of peptide repeating units

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyamides (AREA)

Abstract

Composition associant un aminoglycoside ayant une néphrotoxicité avec un agent inhibiteur de néphrotoxicité à base de polymère d'asparagine ou d'acide aspartique ou des copolymères de ceux-ci et l'unité de dosage réalisée sur la base d'une telle combinaison. La composition comprend notamment un aminoglycoside ou un sel pharmaceutiquement acceptable de celui-ci ayant un potentiel néphrotoxique et au moins 0,002 mole par mole d'aminoglycoside de polyasparagine ou d'acide polyaspartique.
BE0/212851A 1983-04-29 1984-04-27 Composition associant un aminoglycoside ayant une nephrotoxicite avec un agent inhibiteur de nephrotoxicite. BE899542A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/489,999 US4526888A (en) 1983-04-29 1983-04-29 Nephrotoxicity inhibitors for aminoglycoside antibiotics

Publications (1)

Publication Number Publication Date
BE899542A true BE899542A (fr) 1984-10-29

Family

ID=23946189

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/212851A BE899542A (fr) 1983-04-29 1984-04-27 Composition associant un aminoglycoside ayant une nephrotoxicite avec un agent inhibiteur de nephrotoxicite.

Country Status (16)

Country Link
US (1) US4526888A (fr)
JP (1) JPS59206311A (fr)
AU (1) AU560158B2 (fr)
BE (1) BE899542A (fr)
CA (1) CA1227135A (fr)
CH (1) CH660457A5 (fr)
DE (1) DE3415805C2 (fr)
FR (1) FR2544986B1 (fr)
GB (1) GB2139087B (fr)
HK (1) HK74791A (fr)
IE (1) IE57409B1 (fr)
IT (1) IT1218044B (fr)
MY (1) MY100388A (fr)
NL (1) NL8401322A (fr)
SE (1) SE466288B (fr)
ZA (1) ZA843075B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH667874A5 (fr) * 1985-12-19 1988-11-15 Battelle Memorial Institute Polypeptide synthetique biodegradable et son utilisation pour la preparation de medicaments.
US5079234A (en) * 1989-03-23 1992-01-07 Bristol-Myers Squibb Co. Inhibitors of aminoglycoside nephrotoxicity
US5010092A (en) * 1989-12-22 1991-04-23 Wisconsin Alumni Research Foundation Protection against chemically-induced kidney damage by methimazole
CA2048309A1 (fr) * 1990-08-28 1992-03-01 Donald N. Mcgregor Methode et composition inhibant la nephrotoxicite des aminoglycosides
US5663152A (en) * 1995-01-19 1997-09-02 Asahi Kasei Kogyo Kabushiki Kaisha Potentiators for aminoglycosides
US5876623A (en) * 1996-09-20 1999-03-02 Nalco Chemical Company Biodegradable aspartic acid polymers for preventing scale formation in boilers
US5858367A (en) * 1997-03-27 1999-01-12 Case Western Reserve University Methods for screening for antimicrobials utilizing AarC and compositions thereof
US8003595B2 (en) * 2000-03-01 2011-08-23 Cellectis Amino acid sequences facilitating penetration of a substance of interest into cells and/or cell nuclei
JP2004506664A (ja) 2000-08-23 2004-03-04 ウォックハート・リミテッド 無水アジトロマイシンの製造法
JP2004522763A (ja) * 2001-02-20 2004-07-29 ユーエイビー リサーチ ファンデーション リソソーム蓄積症のアミノグリコシド治療
US7345018B2 (en) 2002-04-25 2008-03-18 Reception Aps Method of treating side effects induced by therapeutic agents
WO2004091495A2 (fr) * 2003-04-09 2004-10-28 University Of Utah Research Foundation Compositions et procedes associes a la production d'erythropoietine
FR2858772A1 (fr) * 2003-08-14 2005-02-18 Diatos Composition anti bacterienne, plus particulierement contre les bacteries gram negatif, comprenant un peptide et un agent anti-bacterien avantageusement hydrophobe
ATE533786T1 (de) * 2003-08-14 2011-12-15 Cellectis Aminosäuresequenzen, die das eindringen einer substanz von interesse in zellen und/oder zellkerne erleichtern

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3927204A (en) * 1969-07-03 1975-12-16 Sclavo Inst Sieroterapeut Use of {60 ,{62 -poly-(aspartic acid)-hydroxyalkylamides as a plasma expander
IT1045109B (it) * 1969-07-03 1980-05-10 Inst Sieroterapico E Vaccino G Foli idrossi etil asparagina e metodo per la sua produzione
US4356166A (en) * 1978-12-08 1982-10-26 University Of Utah Time-release chemical delivery system
FR2483748A1 (fr) * 1980-06-06 1981-12-11 Corning Glass Works Procede d'hydrolyse du lactose contenu dans les lactoserums a l'aide de lactase immobilisee

Also Published As

Publication number Publication date
MY100388A (en) 1990-09-17
ZA843075B (en) 1984-12-24
GB2139087A (en) 1984-11-07
IT8420727A0 (it) 1984-04-27
IT1218044B (it) 1990-03-30
SE466288B (sv) 1992-01-27
SE8402333L (sv) 1984-10-30
NL8401322A (nl) 1984-11-16
AU2744284A (en) 1984-11-01
US4526888A (en) 1985-07-02
GB8410804D0 (en) 1984-06-06
JPS59206311A (ja) 1984-11-22
DE3415805C2 (de) 1993-11-25
DE3415805A1 (de) 1985-02-28
HK74791A (en) 1991-09-27
IE841053L (en) 1984-10-29
FR2544986B1 (fr) 1987-06-19
JPH0553776B2 (fr) 1993-08-10
IE57409B1 (en) 1992-08-26
AU560158B2 (en) 1987-04-02
CA1227135A (fr) 1987-09-22
SE8402333D0 (sv) 1984-04-27
GB2139087B (en) 1987-03-25
CH660457A5 (de) 1987-04-30
FR2544986A1 (fr) 1984-11-02

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: *BRISTOL-MYERS CY

Effective date: 20040427