BE892908A - Procede de preparation de derives de l'acide vincaminique par transposition oxydative de la tabersonine ou de la dihydrotabersonine - Google Patents
Procede de preparation de derives de l'acide vincaminique par transposition oxydative de la tabersonine ou de la dihydrotabersonineInfo
- Publication number
- BE892908A BE892908A BE0/207875A BE207875A BE892908A BE 892908 A BE892908 A BE 892908A BE 0/207875 A BE0/207875 A BE 0/207875A BE 207875 A BE207875 A BE 207875A BE 892908 A BE892908 A BE 892908A
- Authority
- BE
- Belgium
- Prior art keywords
- dihydrotabersonine
- tabersonine
- transposition
- oxidative
- preparation
- Prior art date
Links
- JSLDLCGKZDUQSH-RTBUJCADSA-N 19-epivindolinine Natural products O=C(OC)[C@H]1[C@@]23[C@H](C)[C@]4([C@@H]5N(CC=C4)CC[C@]25c2c(N3)cccc2)C1 JSLDLCGKZDUQSH-RTBUJCADSA-N 0.000 title 1
- KILNDJCLJBOWAN-UHFFFAOYSA-N Tabersonine Natural products CCC12CC(=C3N(C)c4cc(OC)ccc4C35CCN(CC=C1)C25)C(=O)OC KILNDJCLJBOWAN-UHFFFAOYSA-N 0.000 title 1
- UXMCFEBDJVHVNH-HOJAQTOUSA-N ac1l52id Chemical class C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C[C@](O)(C(O)=O)N5C2=C1 UXMCFEBDJVHVNH-HOJAQTOUSA-N 0.000 title 1
- 230000001590 oxidative effect Effects 0.000 title 1
- FNGGIPWAZSFKCN-ACRUOGEOSA-N tabersonine Chemical group N1C2=CC=CC=C2[C@]2([C@H]34)C1=C(C(=O)OC)C[C@]3(CC)C=CCN4CC2 FNGGIPWAZSFKCN-ACRUOGEOSA-N 0.000 title 1
- 230000017105 transposition Effects 0.000 title 1
- FNGGIPWAZSFKCN-UHFFFAOYSA-N xi-tabersonine Natural products N1C2=CC=CC=C2C2(C34)C1=C(C(=O)OC)CC3(CC)C=CCN4CC2 FNGGIPWAZSFKCN-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU105281A HU185255B (en) | 1981-04-23 | 1981-04-23 | New process preparing compounds with eburnane skeleton by means of the oxidative transformation of tabersonine or dihydrotabersonine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE892908A true BE892908A (fr) | 1982-08-16 |
Family
ID=10952644
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE0/207875A BE892908A (fr) | 1981-04-23 | 1982-04-20 | Procede de preparation de derives de l'acide vincaminique par transposition oxydative de la tabersonine ou de la dihydrotabersonine |
Country Status (4)
| Country | Link |
|---|---|
| BE (1) | BE892908A (enrdf_load_html_response) |
| DE (1) | DE3214942A1 (enrdf_load_html_response) |
| FR (1) | FR2504531A1 (enrdf_load_html_response) |
| HU (1) | HU185255B (enrdf_load_html_response) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106749230B (zh) * | 2016-12-20 | 2019-01-08 | 东北制药集团股份有限公司 | 一种长春胺的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2332280A1 (fr) * | 1975-11-20 | 1977-06-17 | Kunesch Nicole | Procede de preparation de vincamine et d'epivincamine a partir de la (-) tabersonine |
| FR2358412A1 (fr) * | 1976-07-13 | 1978-02-10 | Parcor | Procede de preparation de la vincamine et d'alcaloides apparentes |
| DE2745415C2 (de) * | 1977-10-08 | 1983-06-23 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur Herstellung von (-)-Vincamin |
| FR2423493A1 (fr) * | 1977-10-19 | 1979-11-16 | Omnium Chimique Sa | Nouveaux composes heterocycliques derives de l'apo-vincamine, leur preparation et leur application comme medicaments, notamment dans le domaine des insuffisances cardio-circulatoires, cerebro-vasculaires et respiratoires |
-
1981
- 1981-04-23 HU HU105281A patent/HU185255B/hu not_active IP Right Cessation
-
1982
- 1982-04-20 BE BE0/207875A patent/BE892908A/fr not_active IP Right Cessation
- 1982-04-21 FR FR8206868A patent/FR2504531A1/fr active Granted
- 1982-04-22 DE DE19823214942 patent/DE3214942A1/de active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2504531A1 (fr) | 1982-10-29 |
| HU185255B (en) | 1984-12-28 |
| FR2504531B1 (enrdf_load_html_response) | 1985-01-04 |
| DE3214942A1 (de) | 1983-02-10 |
| DE3214942C2 (enrdf_load_html_response) | 1992-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: RICHTER GEDEON VEGYESZETI GYAR RT Effective date: 19950430 |