BE843950A - Nouveaux derives anhydro d'alcaloides de vinca - Google Patents

Nouveaux derives anhydro d'alcaloides de vinca

Info

Publication number
BE843950A
BE843950A BE1007493A BE1007493A BE843950A BE 843950 A BE843950 A BE 843950A BE 1007493 A BE1007493 A BE 1007493A BE 1007493 A BE1007493 A BE 1007493A BE 843950 A BE843950 A BE 843950A
Authority
BE
Belgium
Prior art keywords
new
vinca alkaloids
anhydro derivatives
anhydro
derivatives
Prior art date
Application number
BE1007493A
Other languages
English (en)
French (fr)
Inventor
G E Gutowski
J C Miller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE843950A publication Critical patent/BE843950A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BE1007493A 1975-07-10 1976-07-09 Nouveaux derives anhydro d'alcaloides de vinca BE843950A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/594,915 US4029663A (en) 1975-07-10 1975-07-10 Dimeric anhydro-vinca derivatives

Publications (1)

Publication Number Publication Date
BE843950A true BE843950A (fr) 1977-01-10

Family

ID=24380952

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1007493A BE843950A (fr) 1975-07-10 1976-07-09 Nouveaux derives anhydro d'alcaloides de vinca

Country Status (12)

Country Link
US (1) US4029663A (pm)
JP (1) JPS5210300A (pm)
BE (1) BE843950A (pm)
CA (1) CA1057750A (pm)
CH (1) CH625530A5 (pm)
DE (1) DE2630392A1 (pm)
FR (1) FR2316950A1 (pm)
GB (1) GB1548621A (pm)
HU (1) HU179457B (pm)
IE (1) IE43113B1 (pm)
IL (1) IL49706A (pm)
NL (1) NL7607549A (pm)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2296418B1 (pm) * 1974-12-30 1978-07-21 Anvar
US4279817A (en) * 1975-05-30 1981-07-21 The United States Of America As Represented By The Department Of Health & Human Services Method for producing dimer alkaloids
USRE30561E (en) * 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
US4160767A (en) * 1976-12-06 1979-07-10 Eli Lilly And Company Vinca alkaloid intermediates
US4143041A (en) * 1977-01-19 1979-03-06 Eli Lilly And Company 4'-Deoxyvincristine and related compounds
US4166810A (en) * 1978-04-20 1979-09-04 Eli Lilly And Company Derivatives of 4-desacetyl VLB C-3 carboxyhydrazide
AR225153A1 (es) * 1978-10-10 1982-02-26 Lilly Co Eli Un procedimiento para la preparacion de sulfato de vindesina
US4639456A (en) * 1980-06-10 1987-01-27 Omnichem S.A. Vinblastin-23-oyl amino acid derivatives
US4322351A (en) * 1980-08-25 1982-03-30 Eli Lilly And Company Antineoplastic 4'-formylamino and 4'-acetylamino VLB, and derivatives thereof
US4320058A (en) * 1980-12-29 1982-03-16 Eli Lilly And Company 20'-Hydroxyvinblastine and related compounds
HU185691B (en) * 1982-02-09 1985-03-28 Richter Gedeon Vegyeszet Process for preparing a new analgetic pharmaceutical composition
DK167984A (da) * 1983-03-30 1984-10-01 Lilly Industries Ltd Alkaloidderivater
HU193772B (en) * 1985-06-12 1987-11-30 Richter Gedeon Vegyeszet Process for producing new nitro-bis-indole derivatives
US6011041A (en) * 1995-07-28 2000-01-04 University Of British Columbia Use of anhydrovinblastine
CA2219095A1 (en) 1997-03-04 1998-09-04 Bruce Schmidt Anhydrovinblastine for the treatment of cervical and lung cancer
US20030162803A1 (en) * 1997-03-04 2003-08-28 Bruce Schmidt Anhydrovinblastine for the treatment of cancer
AU783029B2 (en) * 1997-03-04 2005-09-15 University Of British Columbia, The Anhydrovinblastine for the treatment of cervical and lung cancer
US6841538B1 (en) 1998-04-22 2005-01-11 Inex Pharmaceuticals Corporation Combination therapy using nucleic acids and radio therapy
US6841537B1 (en) 1998-04-22 2005-01-11 Protiva Biotherapeutics Inc. Combination therapy using nucleic acids and conventional drugs
CA2325561A1 (en) * 1998-04-22 1999-10-28 Inex Pharmaceuticals Corporation Combination therapy using nucleic acids and conventional drugs
EP2289549A3 (en) 1999-10-01 2011-06-15 Immunogen, Inc. Immunoconjugates for treating cancer
WO2005086922A2 (en) * 2004-03-10 2005-09-22 Board Of Regents, University Of Texas System Oncolytic adenovirus armed with therapeutic genes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3097137A (en) * 1960-05-19 1963-07-09 Canadian Patents Dev Vincaleukoblastine
US3392173A (en) * 1964-03-09 1968-07-09 Lilly Co Eli Novel acyl derivatives of desacetyl-vincaleukoblastine and processes for their preparation
US3352868A (en) * 1964-04-01 1967-11-14 Lilly Co Eli Dihydrovinblastine

Also Published As

Publication number Publication date
NL7607549A (nl) 1977-01-12
FR2316950A1 (fr) 1977-02-04
US4029663A (en) 1977-06-14
JPS6220192B2 (pm) 1987-05-06
IL49706A (en) 1979-09-30
CA1057750A (en) 1979-07-03
IL49706A0 (en) 1976-08-31
DE2630392A1 (de) 1977-02-03
CH625530A5 (pm) 1981-09-30
HU179457B (en) 1982-10-28
IE43113L (en) 1977-01-10
IE43113B1 (en) 1980-12-17
JPS5210300A (en) 1977-01-26
FR2316950B1 (pm) 1980-10-17
GB1548621A (en) 1979-07-18

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: ELI LILLY AND CY

Effective date: 19880731