BE838828A - Acides 6-oxo-7-substitue et 7,7-disubstitue-6h-indeno (5,4-b)-furan (et thiophene) carboxyliques - Google Patents
Acides 6-oxo-7-substitue et 7,7-disubstitue-6h-indeno (5,4-b)-furan (et thiophene) carboxyliquesInfo
- Publication number
- BE838828A BE838828A BE164538A BE164538A BE838828A BE 838828 A BE838828 A BE 838828A BE 164538 A BE164538 A BE 164538A BE 164538 A BE164538 A BE 164538A BE 838828 A BE838828 A BE 838828A
- Authority
- BE
- Belgium
- Prior art keywords
- disubstitute
- indeno
- furan
- thiophene
- oxo
- Prior art date
Links
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 title 2
- 150000001735 carboxylic acids Chemical class 0.000 title 1
- 229930192474 thiophene Natural products 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
- C07C49/755—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/552,402 US3984552A (en) | 1975-02-24 | 1975-02-24 | 6-Oxo-7-substituted and 7,7-disubstituted-6H-indeno-[5,4-b]furan (and thiophene) carboxylic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE838828A true BE838828A (fr) | 1976-08-23 |
Family
ID=24205173
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE164538A BE838828A (fr) | 1975-02-24 | 1976-02-23 | Acides 6-oxo-7-substitue et 7,7-disubstitue-6h-indeno (5,4-b)-furan (et thiophene) carboxyliques |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US3984552A (enExample) |
| JP (1) | JPS6154794B2 (enExample) |
| AU (1) | AU500514B2 (enExample) |
| BE (1) | BE838828A (enExample) |
| CA (1) | CA1072972A (enExample) |
| CH (1) | CH617689A5 (enExample) |
| DE (1) | DE2607305C2 (enExample) |
| DK (1) | DK143339C (enExample) |
| ES (1) | ES445380A1 (enExample) |
| FR (1) | FR2301246A1 (enExample) |
| GB (1) | GB1497382A (enExample) |
| HU (1) | HU177120B (enExample) |
| NL (1) | NL7601295A (enExample) |
| SE (1) | SE425605B (enExample) |
| ZA (1) | ZA761046B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4394385A (en) * | 1980-11-21 | 1983-07-19 | Merck & Co., Inc. | Treatment of gray matter edema |
| US6890363B1 (en) * | 1999-05-24 | 2005-05-10 | Showa Denko K.K. | Solid electrolytic capacitor and method for producing the same |
| US6858615B2 (en) | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenyl guanidine sodium channel blockers |
| US6858614B2 (en) * | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenolic guanidine sodium channel blockers |
| US6903105B2 (en) | 2003-02-19 | 2005-06-07 | Parion Sciences, Inc. | Sodium channel blockers |
| US7745442B2 (en) | 2003-08-20 | 2010-06-29 | Parion Sciences, Inc. | Methods of reducing risk of infection from pathogens |
| EA026149B1 (ru) | 2011-06-16 | 2017-03-31 | Корея Рисерч Инститьют Оф Кемикал Текнолоджи | Производное инданона, его фармацевтически приемлемая соль или оптический изомер, способ его получения и содержащая его фармацевтическая композиция для профилактики или лечения вирусного заболевания |
| AR086745A1 (es) | 2011-06-27 | 2014-01-22 | Parion Sciences Inc | 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida |
| PL3882244T3 (pl) | 2012-12-14 | 2025-06-16 | Korea Research Institute Of Chemical Technology | ZWIĄZEK, JEGO FARMACEUTYCZNIE DOPUSZCZALNA SÓL LUB IZOMER OPTYCZNY, SPOSÓB ICH WYTWARZANIA i ZAWIERAJĄCA JE, JAKO SKŁADNIK AKTYWNY, KOMPOZYCJA FARMACEUTYCZNA DO PROFILAKTYKI LUB LECZENIA CHORÓB WIRUSOWYCH |
| HUE032891T2 (hu) | 2012-12-17 | 2017-11-28 | Parion Sciences Inc | Klórpirazin-karboxamid-származékok nem kielégítõ nyálkahártya-hidratáció által elõsegített megbetegedések kezelésére |
| RU2671976C2 (ru) | 2012-12-17 | 2018-11-08 | Пэрион Сайенсиз, Инк. | Соединения 3,5-диамино-6-хлор-n-(n-(4-фенилбутил)карбамимидоил)пиразин-2-карбоксамида |
| US9102633B2 (en) | 2013-12-13 | 2015-08-11 | Parion Sciences, Inc. | Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds |
| CA3176727A1 (en) | 2020-04-20 | 2021-10-28 | Novartis Ag | Antiviral 1,3-di-oxo-indene compounds |
| US12286423B2 (en) | 2020-04-20 | 2025-04-29 | Novartis Ag | Antiviral 1,3-di-oxo-indene compounds |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3931239A (en) * | 1974-04-03 | 1976-01-06 | Merck & Co., Inc. | 6-Oxo-7-substituted-6H-indeno-[5,4-b]furan(and thiophene)-carboxylic acids |
-
1975
- 1975-02-24 US US05/552,402 patent/US3984552A/en not_active Expired - Lifetime
-
1976
- 1976-02-09 NL NL7601295A patent/NL7601295A/xx not_active Application Discontinuation
- 1976-02-10 SE SE7601422A patent/SE425605B/xx not_active IP Right Cessation
- 1976-02-11 DK DK56076A patent/DK143339C/da not_active IP Right Cessation
- 1976-02-13 HU HU76ME1946A patent/HU177120B/hu unknown
- 1976-02-17 CH CH193776A patent/CH617689A5/de not_active IP Right Cessation
- 1976-02-17 AU AU11179/76A patent/AU500514B2/en not_active Expired
- 1976-02-18 CA CA246,059A patent/CA1072972A/en not_active Expired
- 1976-02-19 GB GB6654/76A patent/GB1497382A/en not_active Expired
- 1976-02-20 ES ES445380A patent/ES445380A1/es not_active Expired
- 1976-02-23 DE DE2607305A patent/DE2607305C2/de not_active Expired
- 1976-02-23 ZA ZA761046A patent/ZA761046B/xx unknown
- 1976-02-23 FR FR7604937A patent/FR2301246A1/fr active Granted
- 1976-02-23 BE BE164538A patent/BE838828A/xx not_active IP Right Cessation
- 1976-02-24 JP JP51018581A patent/JPS6154794B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2301246B1 (enExample) | 1980-06-20 |
| ZA761046B (en) | 1977-03-30 |
| GB1497382A (en) | 1978-01-12 |
| DK143339B (da) | 1981-08-10 |
| AU500514B2 (en) | 1979-05-24 |
| DE2607305C2 (de) | 1987-04-30 |
| DK56076A (da) | 1976-08-25 |
| CA1072972A (en) | 1980-03-04 |
| FR2301246A1 (fr) | 1976-09-17 |
| HU177120B (en) | 1981-07-28 |
| SE425605B (sv) | 1982-10-18 |
| DE2607305A1 (de) | 1976-09-02 |
| SE7601422L (sv) | 1976-08-25 |
| AU1117976A (en) | 1977-08-25 |
| NL7601295A (nl) | 1976-08-26 |
| ES445380A1 (es) | 1977-10-01 |
| DK143339C (da) | 1981-12-07 |
| US3984552A (en) | 1976-10-05 |
| CH617689A5 (enExample) | 1980-06-13 |
| JPS51110558A (enExample) | 1976-09-30 |
| JPS6154794B2 (enExample) | 1986-11-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: MERCK & CO. INC. Effective date: 19890228 |