BE832521A - Procede de preparation d'insuline, de ses analogues et derives - Google Patents
Procede de preparation d'insuline, de ses analogues et derivesInfo
- Publication number
- BE832521A BE832521A BE159280A BE159280A BE832521A BE 832521 A BE832521 A BE 832521A BE 159280 A BE159280 A BE 159280A BE 159280 A BE159280 A BE 159280A BE 832521 A BE832521 A BE 832521A
- Authority
- BE
- Belgium
- Prior art keywords
- analogues
- derivatives
- preparing insulin
- insulin
- preparing
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 2
- 102000004877 Insulin Human genes 0.000 title 1
- 108090001061 Insulin Proteins 0.000 title 1
- 229940125396 insulin Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2439296A DE2439296A1 (de) | 1974-08-16 | 1974-08-16 | Verfahren zur herstellung von insulin, insulin-analogen und -derivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE832521A true BE832521A (fr) | 1976-02-18 |
Family
ID=5923333
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE159280A BE832521A (fr) | 1974-08-16 | 1975-08-18 | Procede de preparation d'insuline, de ses analogues et derives |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4013628A (fr) |
| JP (1) | JPS5811428B2 (fr) |
| AU (1) | AU8397675A (fr) |
| BE (1) | BE832521A (fr) |
| CH (1) | CH616651A5 (fr) |
| DE (1) | DE2439296A1 (fr) |
| DK (1) | DK370875A (fr) |
| FR (1) | FR2283124A1 (fr) |
| GB (1) | GB1519026A (fr) |
| IL (1) | IL47920A0 (fr) |
| LU (1) | LU73207A1 (fr) |
| NL (1) | NL7509541A (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2901297A1 (de) * | 1979-01-13 | 1980-07-31 | Hoechst Ag | Neue sulfonierte insuline |
| JPS5962145A (ja) * | 1982-10-02 | 1984-04-09 | ロンシール工業株式会社 | 装飾シ−トの製造方法 |
| US5646242A (en) * | 1994-11-17 | 1997-07-08 | Eli Lilly And Company | Selective acylation of epsilon-amino groups |
| US5700904A (en) * | 1995-06-07 | 1997-12-23 | Eli Lilly And Company | Preparation of an acylated protein powder |
| US5631347A (en) * | 1995-06-07 | 1997-05-20 | Eli Lilly And Company | Reducing gelation of a fatty acid-acylated protein |
| US6323311B1 (en) | 1999-09-22 | 2001-11-27 | University Of Utah Research Foundation | Synthesis of insulin derivatives |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3907763A (en) * | 1972-03-01 | 1975-09-23 | Bayer Ag | Insulin derivatives crosslinked by a dicarboxylic acid moiety |
| US3847893A (en) * | 1972-03-01 | 1974-11-12 | Bayer Ag | Process for the preparation of insulin derivatives cross-linked by a dicarboxylic acid group at the amino a-1 glycine and amino b-29 lysine |
| DE2252157C3 (de) * | 1972-10-25 | 1976-03-18 | Hoechst Ag | Zwischenprodukte zur herstellung von insulin, insulin-analogen und -derivaten und verfahren zur herstellung von insulin, insulin analogen und derivaten |
| NL7314766A (fr) * | 1972-10-31 | 1974-05-02 | ||
| DE2253327A1 (de) * | 1972-10-31 | 1974-05-09 | Hoechst Ag | Verfahren zur herstellung von insulin, insulin-analogen und -derivaten |
-
1974
- 1974-08-16 DE DE2439296A patent/DE2439296A1/de not_active Withdrawn
-
1975
- 1975-08-11 NL NL7509541A patent/NL7509541A/xx unknown
- 1975-08-13 CH CH1055475A patent/CH616651A5/de not_active IP Right Cessation
- 1975-08-14 FR FR7525342A patent/FR2283124A1/fr active Granted
- 1975-08-14 IL IL47920A patent/IL47920A0/xx unknown
- 1975-08-14 LU LU73207A patent/LU73207A1/xx unknown
- 1975-08-14 US US05/604,667 patent/US4013628A/en not_active Expired - Lifetime
- 1975-08-14 AU AU83976/75A patent/AU8397675A/en not_active Expired
- 1975-08-15 DK DK370875A patent/DK370875A/da unknown
- 1975-08-15 JP JP50098657A patent/JPS5811428B2/ja not_active Expired
- 1975-08-15 GB GB34043/75A patent/GB1519026A/en not_active Expired
- 1975-08-18 BE BE159280A patent/BE832521A/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US4013628A (en) | 1977-03-22 |
| LU73207A1 (fr) | 1977-04-13 |
| JPS5811428B2 (ja) | 1983-03-02 |
| DK370875A (da) | 1976-02-17 |
| NL7509541A (nl) | 1976-02-18 |
| FR2283124A1 (fr) | 1976-03-26 |
| CH616651A5 (fr) | 1980-04-15 |
| JPS5148661A (en) | 1976-04-26 |
| IL47920A0 (en) | 1975-11-25 |
| GB1519026A (en) | 1978-07-26 |
| DE2439296A1 (de) | 1976-02-26 |
| AU8397675A (en) | 1977-02-17 |
| FR2283124B1 (fr) | 1978-09-22 |
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