BE792096A - Nouvelles benzylpyrimidines - Google Patents

Nouvelles benzylpyrimidines

Info

Publication number
BE792096A
BE792096A BE792096DA BE792096A BE 792096 A BE792096 A BE 792096A BE 792096D A BE792096D A BE 792096DA BE 792096 A BE792096 A BE 792096A
Authority
BE
Belgium
Prior art keywords
benzylpyrimidines
new
new benzylpyrimidines
Prior art date
Application number
Other languages
English (en)
French (fr)
Inventor
E Grunberg
M Hoffer
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication date
Publication of BE792096A publication Critical patent/BE792096A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/60Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
BE792096D 1971-12-01 Nouvelles benzylpyrimidines BE792096A (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US20386971A 1971-12-01 1971-12-01
US00404954A US3850962A (en) 1971-12-01 1973-10-10 2,4-diamino-5-(3-alkoxy-4,5-methylene-dioxybenzyl)pyrimidine
US404953A US3867527A (en) 1971-12-01 1973-10-10 2,4-Diamino-5-(3-alkoxy-4,5-methylenedioxybenzyl)pyrimidine
US05/531,135 US3962435A (en) 1971-12-01 1974-12-09 Combination of oxytetracycline and 2,4-diamino-5-(3-alkoxy-4,5-methylenedioxybenzyl)pyrimidine

Publications (1)

Publication Number Publication Date
BE792096A true BE792096A (fr) 1973-05-30

Family

ID=27498515

Family Applications (1)

Application Number Title Priority Date Filing Date
BE792096D BE792096A (fr) 1971-12-01 Nouvelles benzylpyrimidines

Country Status (12)

Country Link
US (3) US3867527A (sv)
JP (1) JPS5523830B2 (sv)
AT (1) AT321310B (sv)
AU (1) AU467566B2 (sv)
BE (1) BE792096A (sv)
CA (1) CA994345A (sv)
CH (1) CH569009A5 (sv)
DE (1) DE2252807A1 (sv)
FR (1) FR2162177B1 (sv)
GB (2) GB1388180A (sv)
NL (1) NL176563C (sv)
SE (3) SE397349B (sv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA738760B (en) * 1972-12-21 1974-08-28 Hoffmann La Roche Process for the manufacture of benzyl pyrimidines
US3978086A (en) * 1973-04-13 1976-08-31 Sandoz, Inc. 2-Amino-4,5-methylenedioxyphenyl nitriles
US3996355A (en) * 1975-01-02 1976-12-07 American Home Products Corporation Permanent suspension pharmaceutical dosage form
US4075209A (en) * 1977-02-07 1978-02-21 Hoffmann-La Roche, Inc. Process for preparing substituted 2,4-diaminopyrimidines and isoxazole intermediate
AT384023B (de) * 1980-11-11 1987-09-25 Wellcome Found Verfahren zur herstellung von neuen 2,4-diamino-5-(subst.)pyrimidinen und deren salzen, n-oxiden und n-acylderivaten
US4438267A (en) * 1980-11-11 1984-03-20 Daluge Susan M Monoheteroring compounds and their use
WO2020067442A1 (ja) 2018-09-27 2020-04-02 テルモ株式会社 細胞の凍結保存方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2628236A (en) * 1953-02-10 S-benzyl
DE1303727B (de) * 1959-09-03 1976-02-05 Ausscheidung aus: 14 45 176 The Wellcome Foundation Ltd., London Alpha-Arylidensubstituierte Propioni-Irile
NL122146C (sv) * 1960-09-02
US3485840A (en) * 1964-11-12 1969-12-23 Hoffmann La Roche 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes
FR1453056A (fr) * 1964-11-12 1966-04-15 Hoffmann La Roche Procédé pour la préparation de dérivés de pyrimidine
DE1620729A1 (de) * 1965-07-08 1970-08-20 Wellcome Found Verfahren zur Herstellung von substituierten Benzylpyrimidinen
DK120706B (da) * 1969-01-27 1971-07-05 Egyt Gyogyszervegyeszeti Gyar Fremgangsmåde til fremstilling af 2,4-diamino-5-(3',4',5'-trimethoxybenzyl)-pyrimidin.
CH513181A (de) * 1969-06-12 1971-09-30 Hoffmann La Roche Verfahren zur Herstellung von N-Oxyden von Benzylpyrimidinen
US3787409A (en) * 1970-09-14 1974-01-22 Hoffmann La Roche 2,4-diamino-5-(3-alkoxy-4,5-methylenedioxybenzyl)pyrimidine
RO67383A (ro) * 1970-10-22 1981-07-30 The Wellcome Foundation Ltd,Gb Procedeu pentru prepararea unor 2,4-diamino-5-benzilpirimidine
GB1375162A (sv) * 1970-10-22 1974-11-27
DE2165363A1 (de) * 1970-12-29 1972-07-27 Nisshin Flour Milling Co. Ltd., Tokio Verfahren zur Herstellung von Pyrimidinderivaten

Also Published As

Publication number Publication date
US3867527A (en) 1975-02-18
AT321310B (de) 1975-03-25
DE2252807A1 (de) 1973-06-07
SE7513517L (sv) 1975-12-01
CH569009A5 (sv) 1975-11-14
FR2162177B1 (sv) 1975-08-08
US3850962A (en) 1974-11-26
JPS5523830B2 (sv) 1980-06-25
GB1388180A (en) 1975-03-26
AU4846272A (en) 1974-05-02
NL176563C (nl) 1985-05-01
NL7215587A (sv) 1973-06-05
CA994345A (en) 1976-08-03
SE397349B (sv) 1977-10-31
FR2162177A1 (sv) 1973-07-13
SE7507943L (sv) 1975-07-10
GB1388178A (en) 1975-03-26
JPS4862769A (sv) 1973-09-01
NL176563B (nl) 1984-12-03
US3962435A (en) 1976-06-08
AU467566B2 (en) 1975-12-04

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: F. HOFFMANN-LA ROCHE & CIE S.A.

Effective date: 19861130