BE763689A - Composes de 2-thiomethyl- et 2-thiomethylene-delta3-cephalosporine et leurs sulfoxydes - Google Patents

Composes de 2-thiomethyl- et 2-thiomethylene-delta3-cephalosporine et leurs sulfoxydes

Info

Publication number
BE763689A
BE763689A BE763689A BE763689A BE763689A BE 763689 A BE763689 A BE 763689A BE 763689 A BE763689 A BE 763689A BE 763689 A BE763689 A BE 763689A BE 763689 A BE763689 A BE 763689A
Authority
BE
Belgium
Prior art keywords
delta3
thiomethylene
thiomethyl
sulfoxides
cephalosporin compounds
Prior art date
Application number
BE763689A
Other languages
English (en)
French (fr)
Inventor
I G Wright
G V Kaiser
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BE763689A publication Critical patent/BE763689A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE763689A 1970-03-04 1971-03-03 Composes de 2-thiomethyl- et 2-thiomethylene-delta3-cephalosporine et leurs sulfoxydes BE763689A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1656170A 1970-03-04 1970-03-04

Publications (1)

Publication Number Publication Date
BE763689A true BE763689A (fr) 1971-09-03

Family

ID=21777764

Family Applications (1)

Application Number Title Priority Date Filing Date
BE763689A BE763689A (fr) 1970-03-04 1971-03-03 Composes de 2-thiomethyl- et 2-thiomethylene-delta3-cephalosporine et leurs sulfoxydes

Country Status (9)

Country Link
US (1) US3660395A (enExample)
JP (1) JPS55162792A (enExample)
BE (1) BE763689A (enExample)
CH (1) CH585759A5 (enExample)
DE (1) DE2110387C3 (enExample)
ES (1) ES388866A1 (enExample)
FR (1) FR2128096B1 (enExample)
GB (1) GB1300718A (enExample)
NL (1) NL7102928A (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3852282A (en) * 1969-04-01 1974-12-03 Squibb & Sons Inc Certain 2-substituted cephalosporins
US4123612A (en) * 1970-08-10 1978-10-31 Eli Lilly And Company 7-(5-Amino-5-carboxyvaleramido)-3-(carbamoyoloxymethyl)-3-cephem-4-carboxylic acid
US3932393A (en) * 1971-02-25 1976-01-13 Eli Lilly And Company 3-Methylenecephalosporins and process for production thereof
US3923795A (en) * 1972-06-19 1975-12-02 Lilly Co Eli 2-Alkoxycephalosporins
US4098999A (en) * 1972-10-16 1978-07-04 E. R. Squibb & Sons, Inc. Certain 2-substituted cephalosporins
JPS49116087A (enExample) * 1973-03-14 1974-11-06
US3933806A (en) * 1973-07-17 1976-01-20 Eli Lilly And Company Cephalosporin michael adducts
US3907785A (en) * 1973-07-17 1975-09-23 Lilly Co Eli Tricyclic cephalosporins
US3941779A (en) * 1973-11-12 1976-03-02 E. R. Squibb & Sons, Inc. Method for producing 2-(substituted thio)-3-cephem derivatives
US3968109A (en) * 1973-11-23 1976-07-06 E. R. Squibb & Sons, Inc. Production of 2-(thio substituted)cephalosporin sulfoxides and 2-(thio substituted)cephalosporins
US4049806A (en) * 1975-08-15 1977-09-20 Syntex (U.S.A.) Inc. Cephalosporin type antibacterials
US3983113A (en) * 1975-08-15 1976-09-28 Syntex (U.S.A.) Inc. Cephalosporin type antibacterials
US4145538A (en) * 1976-05-06 1979-03-20 Eli Lilly And Company 3-Carbamyloxymethyl-cephalosporins
US5037975A (en) * 1988-09-16 1991-08-06 Eli Lilly And Company Cephalosporin free radical compounds
US4939249A (en) * 1988-09-16 1990-07-03 Eli Lilly And Company Process for 1-carba(dethia) cephalosporins

Also Published As

Publication number Publication date
US3660395A (en) 1972-05-02
DE2110387C3 (de) 1979-12-13
FR2128096A1 (enExample) 1972-10-20
CH585759A5 (enExample) 1977-03-15
FR2128096B1 (enExample) 1974-09-06
DE2110387B2 (de) 1979-04-26
JPS55162792A (en) 1980-12-18
NL7102928A (enExample) 1971-09-07
GB1300718A (en) 1972-12-20
ES388866A1 (es) 1973-06-01
DE2110387A1 (de) 1971-09-16

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