BE751790A - N-oxydes de benzyl-pyrimidines - Google Patents

N-oxydes de benzyl-pyrimidines

Info

Publication number
BE751790A
BE751790A BE751790DA BE751790A BE 751790 A BE751790 A BE 751790A BE 751790D A BE751790D A BE 751790DA BE 751790 A BE751790 A BE 751790A
Authority
BE
Belgium
Prior art keywords
pyrimidine
benzyl
oxides
Prior art date
Application number
Other languages
English (en)
French (fr)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BE751790A publication Critical patent/BE751790A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Structures Of Non-Positive Displacement Pumps (AREA)
BE751790D 1969-06-12 1970-06-11 N-oxydes de benzyl-pyrimidines BE751790A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH897069A CH513181A (de) 1969-06-12 1969-06-12 Verfahren zur Herstellung von N-Oxyden von Benzylpyrimidinen

Publications (1)

Publication Number Publication Date
BE751790A true BE751790A (fr) 1970-12-11

Family

ID=4346865

Family Applications (1)

Application Number Title Priority Date Filing Date
BE751790D BE751790A (fr) 1969-06-12 1970-06-11 N-oxydes de benzyl-pyrimidines

Country Status (18)

Country Link
US (1) US3715357A (pl)
AT (1) AT294843B (pl)
BE (1) BE751790A (pl)
BR (1) BR6915095D0 (pl)
CA (1) CA955944A (pl)
CH (1) CH513181A (pl)
DE (1) DE2026997A1 (pl)
DK (1) DK124682B (pl)
ES (1) ES380642A1 (pl)
FR (1) FR2052954B1 (pl)
GB (1) GB1256849A (pl)
IE (1) IE34683B1 (pl)
IL (1) IL34632A (pl)
NL (1) NL7008610A (pl)
NO (1) NO127237B (pl)
SE (1) SE367412B (pl)
YU (1) YU33390B (pl)
ZA (1) ZA703569B (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993761A (en) * 1971-12-01 1976-11-23 Hoffmann-La Roche Inc. Antibacterial compositions
BE792096A (fr) * 1971-12-01 1973-05-30 Hoffmann La Roche Nouvelles benzylpyrimidines
AR204082A1 (es) * 1972-06-26 1975-11-20 Hoffmann La Roche Procedimiento para preparar derivados de n-oxidos de 2,4-diamino-5-(3-metoxi-4,5-metilendioxibencil)pirimidina
US4515948A (en) * 1973-09-12 1985-05-07 Hoffmann-La Roche Inc. 2,4-Diamino-5-(4-amino and 4-dimethylamino-3,5-dimethoxy benzyl)pyrimidines
US4076810A (en) * 1973-11-08 1978-02-28 Hoffmann-La Roche Inc. Benzylpyrimidine antibacterial composition
CH591457A5 (pl) * 1973-11-08 1977-09-15 Hoffmann La Roche
WO2003043979A2 (en) * 2001-11-20 2003-05-30 Dana Farber Cancer Institute Pharmaceutically active compounds and methods of use thereof
KR100822530B1 (ko) 2004-03-05 2008-04-16 에프. 호프만-라 로슈 아게 Ｐ2ｘ3 및 ｐ2ｘ2/3 길항물질로서의 다이아미노피리미딘
JP4850913B2 (ja) * 2005-09-01 2012-01-11 エフ．ホフマン−ラ ロシュ アーゲー Ｐ２ｘ３及びｐ２ｘ２／３調節因子としてのジアミノピリジン
CN101253159B (zh) * 2005-09-01 2011-12-07 弗·哈夫曼-拉罗切有限公司 作为p2x3和p2x2/3调节剂的二氨基嘧啶类化合物
EP1924564B1 (en) * 2005-09-01 2016-11-09 F.Hoffmann-La Roche Ag Diaminopyrimidines as p2x3 and p2x2/3 modulators

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2518130A (en) * 1945-04-26 1950-08-08 Evans N-oxides of tertiary amines and process of preparing same
US2500131A (en) * 1945-06-27 1950-03-07 Ralph L Evans Di-nu-oxides of amino-substituted acridines and quinolines
US3159628A (en) * 1962-05-28 1964-12-01 Smith Kline French Lab Pteridine-5-oxide derivatives
FR1453056A (fr) * 1964-11-12 1966-04-15 Hoffmann La Roche Procédé pour la préparation de dérivés de pyrimidine
US3485840A (en) * 1964-11-12 1969-12-23 Hoffmann La Roche 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes
US3382247A (en) * 1965-11-01 1968-05-07 Upjohn Co 6-amino-1, 2-dihydro-1-hydroxy-2-imino-4-phenoxypyrimidines
US3464987A (en) * 1966-02-21 1969-09-02 Upjohn Co 1,2-dihydro-1-hydroxy-2-imino-6-(lower alkyl)pyrimidines

Also Published As

Publication number Publication date
FR2052954A1 (pl) 1971-04-16
NL7008610A (pl) 1970-12-15
ES380642A1 (es) 1972-10-16
FR2052954B1 (pl) 1973-08-10
SE367412B (pl) 1974-05-27
IL34632A (en) 1973-08-29
DK124682B (da) 1972-11-13
DE2026997A1 (pl) 1970-12-23
NO127237B (pl) 1973-05-28
CA955944A (en) 1974-10-08
IL34632A0 (en) 1970-08-19
GB1256849A (pl) 1971-12-15
AT294843B (de) 1971-12-10
IE34683L (en) 1970-12-12
IE34683B1 (en) 1975-07-23
YU33390B (en) 1976-12-31
YU132870A (en) 1976-06-30
US3715357A (en) 1973-02-06
CH513181A (de) 1971-09-30
BR6915095D0 (pt) 1973-03-08
ZA703569B (en) 1971-01-27

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